Patents Assigned to D
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Patent number: 12012077Abstract: The present invention relates to an adapter (1) for a wiper system (6), comprising at least a side wall (10) and an upper wall (12) having at least one common edge between them, the side wall (10) and the upper wall (12) helping to define an inner volume of the adapter (1), the adapter (1) comprising a first inner wall (20) and a second inner wall (66) helping to delimit, at least partially, a receiving area (26) intended to receive the connector (8), the adapter (1) comprising at least one receiving housing (32) which is intended to receive the arm and which has a rectangular cross section defined by two major sides (33) and two minor sides (31), characterized in that a straight line (D) passing through one of the major sides (33) cuts the receiving area (26) intended to receive the connector (8).Type: GrantFiled: September 1, 2022Date of Patent: June 18, 2024Assignee: VALEO SYSTÈMES D'ESSUYAGEInventors: Vincent Gaucher, Stephane Houssat, Eric Poton, Olivier Jomard
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Patent number: 12012065Abstract: The present disclosure relates to a protective device (10, 110) for the protection of a user. The protective device (10) comprises a mesh structure (11, 111) comprising a first mesh portion (18, 118) and a second mesh portion (19, 119) and a plurality of tie elements (5), wherein said first mesh portion (18, 118) and said second mesh portion (19, 119) are opposite one another and are connected one another by the plurality of tie elements (5); wherein the first mesh portion, the second mesh portion and the tie elements define one or more inner housings of the mesh structure (11, 111). The protective device (10, 110) includes a casing body (40, 42, 43) disposed in one or more of said inner housings, wherein said casing body is configured to assume a deflated condition and an inflated condition in the one or more inner housings of the mesh structure (11, 111).Type: GrantFiled: December 9, 2020Date of Patent: June 18, 2024Assignee: D-AIR LAB S.R.L.Inventor: Lino Dainese
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Patent number: 12015933Abstract: A wireless networking system is disclosed. The wireless networking system includes an application layer associated with one or more applications having a wireless bandwidth requirement. A first wireless transceiver resource associated with an actual MAC layer and PHY layer is employed. The first wireless transceiver resource has a first bandwidth availability up to a first actual bandwidth. A second wireless transceiver resource associated with the actual MAC layer and the PHY layer is employed. The second wireless transceiver resource has a second bandwidth availability up to a second actual bandwidth. A processing layer evaluates the wireless bandwidth requirement and the first and second bandwidth availabilities of the wireless transceiver resources. The processing layer includes a bandwidth allocator to allocate at least a portion of each of the first and second actual bandwidths to virtual MAC and virtual PHY layers, and to satisfy the application layer wireless bandwidth requirement.Type: GrantFiled: March 4, 2024Date of Patent: June 18, 2024Assignee: XiFi Networks R&D Inc.Inventor: Sai C. Manapragada
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Patent number: 12012939Abstract: A lightning protection subsystem for a wind blade is presented. The lightning protection subsystem includes one or more conductive segments, where each of the one or more conductive segments include a conductor and a coupling portion, where the coupling portion is configured to secure the one or more conductive segments to an edge of the wind blade. Further, the one or more conductive segments form an elongated lightning conducting path along at least a portion of the length of the edge, at an outer surface of the wind blade.Type: GrantFiled: June 1, 2021Date of Patent: June 18, 2024Assignee: LM Wind Power R&D (Holland) B.V.Inventor: Laszlo Bartha
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Publication number: 20240189212Abstract: The present invention is in the field of antiperspirant compositions, in particular, compositions comprising antiperspirant actives. Disclosed is an antiperspirant composition comprising (i) at least one hydrophobic sorbitan ester having HLB value between 1 and 7.0; (ii) at least one hydrophilic sorbitan ester having HLB value between 7.0 and 20; (iii) at least one organic compound selected from C7-C24 fatty acid, or C7-C24 fatty alcohol; and (iv) a cosmetically acceptable carrier; wherein said composition comprises less than 50% of water; wherein said composition comprises at least 2% said hydrophobic sorbitan ester by weight of the composition; wherein the weight ratio of organic compound to the combination of the hydrophobic sorbitan ester and the hydrophilic sorbitan ester is from 1:10 to 5:1; wherein the composition is free from antiperspirant active which comprises aluminium or zirconium.Type: ApplicationFiled: April 18, 2022Publication date: June 13, 2024Applicant: Conopco, Inc., d/b/a UNILEVERInventors: Xiaoke LI, Weining LIU, Weichong WANG
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Publication number: 20240189202Abstract: The invention is directed to a hydratable concentrated surfactant composition. The composition is pourable, easy to dilute, substantially free of sulfate and oil, comprises a C6-C14 acid, alcohol, amide or mixture thereof, anionic surfactant and an amphoteric surfactant, zwitterionic surfactant or both. The composition is in lamellar phase and thickens and transforms to an isotropic phase upon dilution. The composition is substantially free of isethionates, can be used as a concentrate in small volumes and diluted as used and needed or can be diluted with water in refill packaging to ensure a reduction in plastic waste.Type: ApplicationFiled: April 25, 2022Publication date: June 13, 2024Applicant: CONOPCO, INC., D/B/A UNILEVERInventors: Douglas John Hiban, Teanoosh Moaddel, Tirucherai Varahan Vasudevan
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Publication number: 20240191044Abstract: An ultra-thin elastomer sheet has a maximum film thickness of 3 ?m and composed of a crosslinked silicone polymer in which a silicone polymer configured from unit portions having reactive organic groups and unit portions not having reactive organic groups is crosslinked by a crosslinking agent having a reaction group reacting with the reactive organic groups, the crosslinked silicone polymer is defined by the following mathematical formula: U=(Um+Un)/Ua??(I) where, U is a number of monomer unit portions between crosslinking points of the crosslinked silicone polymer, Um is a number of monomer unit portions of the silicone polymer not having reactive organic groups, Un is a number of monomer unit portions of the silicone polymer having reactive organic groups, and Ua is a number of reaction groups of the crosslinking agent used in crosslinking and the number of monomer unit portions between crosslinking points of the crosslinked silicone polymer is 348-2090.Type: ApplicationFiled: October 27, 2021Publication date: June 13, 2024Applicant: ASAHI FR R&D CO., LTD.Inventors: Shinji TAKEOKA, Syo MIHARA, Nobuyoshi WATANABE
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Publication number: 20240189188Abstract: Medical devices and methods of use thereof are described. The device may include a body having a housing that defines a lumen, a piston within the housing, and an actuator operably coupled to the piston, wherein the piston is movable along the lumen by operating the actuator. The device also may include a cartridge insertable into the body and/or a flexible fitting configured for direct application to an eye of a subject.Type: ApplicationFiled: February 16, 2024Publication date: June 13, 2024Applicant: D&D Biopharmaceuticals, Inc.Inventors: Bruce H. DeWOOLFSON, Dale P. DeVORE, Michael LUTTRELL, Chris L. DAVIS
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Patent number: 12006525Abstract: The application relates to the production of RNA of interest, more specifically of messenger RNA of interest or of long non-coding RNA of interest, by yeasts with recombinant pseudo-viral particles. The recombinant yeasts have been genetically modified in order to produce the RNA of interest in the form of a complex, particularly in the form of recombinant pseudo-viral particles. These recombinant pseudo-viral particles are produced from certain elements of yeast Ty retrotransposon, but do not retrotranscribe the RNA that they contain. Thus, the application relates to the components that are thus capable of being implemented or produced, and particularly to the nucleic acid constructs, kits, bacteria cells, yeast cells, culture or transfection media containing them, as well as to a method for producing a pharmaceutical composition, particularly for medical applications, more specifically for vaccines, anti-tumour and pro-regenerative applications.Type: GrantFiled: March 21, 2018Date of Patent: June 11, 2024Assignees: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, UNIVERSITE D'ORLEANSInventors: Lucie Pigeon, Rachid A. Rahmouni, Harivony Chantal Pichon-Rabenandrasana, Patrick Midoux
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Patent number: 12005424Abstract: The invention discloses a separation matrix comprising polysaccharide gel beads, wherein said polysaccharide gel beads comprise embedded fibers. The invention further discloses a method of preparing the separation matrix and use of the matrix for separation purposes.Type: GrantFiled: April 24, 2019Date of Patent: June 11, 2024Assignee: Cytiva BioProcess R&D ABInventors: Jonas Bengtsson, Linn Carlsson, Andreas Axen, Ronnie Palmgren
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Patent number: 12007393Abstract: The invention provides a method allowing to determine whether a subject diagnosed with cancer is sensitive or resistant to an anti-cancer treatment, based on the level of cells with RAD51 foci in a sample containing tumor cells isolated from said subject, wherein the subject has not received at 24 hours prior to the isolation of the sample, a chemotherapy selected from the group consisting of AC, FEC, ECF and navelbine/epirubicin, and wherein the sample has not been treated with a method that induces DNA damage before determining the level of cells with RAD51 foci.Type: GrantFiled: December 21, 2018Date of Patent: June 11, 2024Assignees: FUNDACIÓ PRIVADA INSTITUT D'INVESTIGACIÓ ONCÒLOGICA DE VALL HEBRON, ASTRAZENECA UK LIMITED, XENTECH SASInventors: Violeta Serra Elizalde, Judith Balmaña Gelpi, Cristina Cruz Zambrano, Alba Llop Guevara, Marta Castroviejo Bermejo, Mark J. O'Connor, Gemma Nicole Jones
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Patent number: 12006085Abstract: The enclosed disclosure describes, among other things, a method including the steps of a first deaerating step in which a mixture comprising peptides is deaerated by lowering the pressure, filtering the mixture through a sterilizing filter; and a second deaerating step, in which the filtrate is deaerated by vibration and lowering the pressure.Type: GrantFiled: June 4, 2022Date of Patent: June 11, 2024Assignee: 3-D Matrix, Ltd.Inventors: Masahiro Nohara, Yuya Hasegawa
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Patent number: 12006311Abstract: The present invention relates to compounds of formula (I) for use in preventing and/or treating cancer.Type: GrantFiled: July 1, 2019Date of Patent: June 11, 2024Assignees: FUNDACIÓ HOSPITAL UNIVERSITARI VALL D'HEBRONINSTITUT DE RECERCA, INSTITUT UNIV. DE CIÈNCIA I TECNOLOGIA, S. A.Inventors: Josep Roma Castanyer, Marta Pascual Gilabert, José Sánchez De Toledo Codina, Soledad Gallego Melcón, Patricia Zarzosa Martínez, Javier Alonso Fernández, Sergio Pérez Ozcáriz, Cristina López Gómez, Josep Castells Boliart
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Patent number: 12007719Abstract: Device for displaying phases of the moon with a fist display member (80) bearing a plurality of first images (81-86) at least partially representing the moon, a display zone, driving means (22, 23, 25, 40, 41, 43, 63, 71, 72, 61, 62) arranged to displace, by successive jumps, the first display member (80) relative to the display zone, to display a succession of representations of the moon. An original feature of the invention is that the periods of display of the first images are not all equal.Type: GrantFiled: June 18, 2019Date of Patent: June 11, 2024Assignee: Manufacture D'Horlogerie Audemars Piguet SAInventors: Giulio Papi, Julien Martel
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Patent number: 12006343Abstract: Compounds for use in the prevention and/or treatment of immunological diseases, particularly rheumatoid arthritis, systemic lupus erythematosus and lupus nephritis, are described, characterized by the subcutaneous administration of isoforms of C4BP lacking the beta chain or polypeptides comprising the CCP6 region of the alpha chain of C4BP no more than once a week or at a dose ranging from 0.24 mg/m2 to 9.99 mg/m2. Pharmaceutical compositions comprising from 0.45 mg to 18.90 mg of these compounds for the prevention and/or treatment of these diseases are also described.Type: GrantFiled: April 5, 2018Date of Patent: June 11, 2024Assignee: FUNDACIO INSTITUT D'INVESTIGACIO BIOMEDICA DE BELLVITGE (IDIBELL)Inventors: Josep M. Aran Perramon, Luis Antonio Ruiz Avila, Jordi Ortiz Sagrista, Nuria Lluch Lafuente
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Publication number: 20240182838Abstract: A method for porating cells for loading with a substance, preferably nuclides for radiotherapy, performs porating in a porating device with cells to be porated in a liquid with the substance. The cell membranes are permeabilized by sonoporation or laser poration, then the cells are incubated in a porating device incubation section. Moreover, a device for porating cells, in particular by sonoporation or laser porating, and for loading cells, particularly immunocompetent cells, in particular ?? T cells, includes inlet and outlet openings for a cell solution with cells to be porated and a substance to be taken up by the cells as a load and preferably microbubbles. A poration arrangement extending between the openings has a collector at the inlet opening for collecting cell solution and a reactor in flow connection with the collector. Inside the reactor the cell membranes may be porated and the cells may uptake the load.Type: ApplicationFiled: November 30, 2023Publication date: June 6, 2024Applicant: Horia Hulubei National Institute for R & D in Physics and Nuclear Engineering (IFIN-HH)Inventor: Klaus SPOHR
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Publication number: 20240181995Abstract: The invention relates to a device (5) comprising an optical surface (10) and a cleaning device (15) for cleaning the optical surface comprising:— a wave transducer (25) acoustically coupled with the optical surface and configured to synthesize an ultrasound wave (W) propagating within the optical surface, and— a spraying unit (20) for dispensing a washing liquid (L) onto the optical surface, the device being shaped so that the ultrasound wave displaces the washing liquid on the optical surface.Type: ApplicationFiled: March 29, 2022Publication date: June 6, 2024Applicants: UNIVERSITE DE LILLE, CENTRALE LILLE INSTITUT, UNIVERSITE POLYTECHNIQUE HAUTS-DE-FRANCE, Centre National de la Recherche Scientifique, Valeo Systèmes d'EssuyageInventors: Michaël Baudoin, Ravinder Chutani, Olivier Bou Matar-Lacaze, Frederic Bretagnol, Vincent Izabel, Gérald Caillot, Alexandre Filloux
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Publication number: 20240181096Abstract: A method for loading immunocompetent cells with nanoparticles and/or a cytotoxic substance is for use in the theranostic treatment of patient-specific genetically modified cells. The method includes the steps: (a) providing immunocompetent cells; and (b) loading the immunocompetent cells with the nanoparticles and/or the cytotoxic substance, wherein the nanoparticles and/or the cytotoxic substance are nuclides for radiotherapy. The loading step includes (i) applying the nanoparticles and/or the cytotoxic substance to the immunocompetent cells or mixing the nanoparticles and/or the cytotoxic substance with the immunocompetent cells in a liquid carrier; and (ii) poration of the immunocompetent cells in order to increase the permeability of the cell membranes of the immunocompetent cells for the nanoparticles and/or the cytotoxic substance and thereby loading the immunocompetent cells with the nanoparticles and/or the cytotoxic substance.Type: ApplicationFiled: November 30, 2023Publication date: June 6, 2024Applicant: Horia Hulubei National Institute for R & D in Physics and Nuclear Engineering (IFIN-HH)Inventor: Klaus SPOHR
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Publication number: 20240181075Abstract: The present invention relates to an antibody-drug conjugate comprising a monoclonal antibody or an antigen-binding fragment thereof wherein the monoclonal antibody or the antigen-binding fragment thereof binds to Nectin-4 and wherein the drug is an amatoxin, particularly ?-amanitin.Type: ApplicationFiled: March 31, 2022Publication date: June 6, 2024Applicants: EMERGENCE THERAPEUTICS AG, UNIVERSITE D’AIX-MARSEILLE, INSERM (INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE), INSTITUT JEAN PAOLI & IRENE CALMETTES, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE – CNRSInventors: Jack ELANDS, Florence LHOSPPICE, Xavier PRÉVILLE, Daniel OLIVE, Marc LOPEZ
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Patent number: D1031443Type: GrantFiled: October 9, 2020Date of Patent: June 18, 2024Assignee: SOCIETE ANONYME DES EAUX MINERALES D'EVIANInventors: Jean-Baptiste Tanchette, Alain Colloud