Abstract: A wiper of a wiper system for a vehicle is disclosed. The wiper includes at least one wiper blade carried by a support and configured to wipe a glazed surface of a vehicle. The wiper includes a spoiler configured to be connected to a cleaning system distributing cleaning liquid. The spoiler includes a body in which a spray manifold for the cleaning fluid is provided. The spray manifold is configured to be connected to the cleaning system. The spray manifold extends in a main direction of extension of the spoiler and the spray manifold includes at least one row of spray holes. The number of spray holes per row is between 1 and 60 over a portion of the spoiler measuring 10 mm in the main direction of extension of the spoiler.

Abstract: The present invention is directed to a system for testing printed circuit boards. The system is configured to test the simultaneously test a multiplicity of printed circuit boards. The system examines the electrical characteristics of a printed circuit board and is operable to identify if a printed circuit board meets a desired characteristic.

Abstract: A method for manufacturing a detector of a first and a second incident ionizing radiation including determining the abscissa em of a point of intersection between a first and a second curve, with the first and second curves representing the evolution of the number of photons or electrical charges generated per second by a transducing material as a function of the total thickness of an amplifying material when the transducing material is irradiated, through this thickness of transducing material, by the first and second incident ionizing radiation, respectively; then selecting the total thickness of amplifying material between 0.9 em and 1.1 em and producing the detector with the selected thickness of amplifying material.

Abstract: The method of identifying a potentially surgically operable target zone in an epileptic patient's brain includes: providing a computerized platform modelling various zones of a primate brain and connectivity between said zones; providing a model of an epileptogenic zone and a model of the propagation of an epileptic discharge from an epileptic zone to a propagation zone; obtaining a patient's personalized computerized platform; deriving the potential target zones based on modularity analysis; evaluating the target zones' effectiveness by simulating epileptic seizures propagation in the personalized patient's computerized platform; evaluating the target zones' safety by simulating spatiotemporal brain activation patterns in a defined state condition and comparing the simulated spatiotemporal brain activation patterns obtained before removal of the target zone with the spatiotemporal brain activation patterns obtained after removal of the target zone; identifying the target zones which satisfy both effectivenes

Abstract: Computational systems implement problem solving using hybrid digital/quantum computing approaches. A problem may be represented as a problem graph which is larger and/or has higher connectivity than a working and/or hardware graph of a quantum processor. A quantum processor may be used determine approximate solutions, which solutions are provided as initial states to one or more digital processors which may implement classical post-processing to generate improved solutions. Techniques for solving problems on extended, more-connected, and/or “virtual full yield” variations of the processor's actual working and/or hardware graphs are provided. A method of operation in a computational system comprising a quantum processor includes partitioning a problem graph into sub-problem graphs, and embedding a sub-problem graph onto the working graph of the quantum processor. The quantum processor and a non-quantum processor-based device generate partial samples.

Abstract: The present invention relates to a system for cleaning at least two sensors/transmitters for a motor vehicle, the system comprising at least one first device for projecting a cleaning fluid onto at least one first sensor/transmitter, at least one second device for projecting a cleaning fluid onto at least one second sensor/transmitter, at least one reservoir, at least one circuit for distribution of the cleaning fluid, connecting the reservoir to the first and second projection devices, at least one electronic pump, and at least one control unit, characterized in that the control unit is configured to receive information on a request for activation of the first and/or second projection device(s) in order to determine a theoretical value of at least one operating parameter of a pump.

Abstract: This disclosure provides various TcBuster transposases and transposons, systems, and methods of use.

Abstract: An Fc-binding polypeptide of improved alkali stability, comprising a mutant of a parental Fc-binding domain of Staphylococcus Protein A (SpA), as defined by SEQ ID NO: 1, SEQ ID NO: 2, SEQ ID NO: 3, SEQ ID NO: 4, SEQ ID NO: 5, SEQ ID NO: 6, SEQ ID NO: 7, SEQ ID NO: 22, SEQ ID NO: 51 or SEQ ID NO: 52, wherein at least the asparagine or serine residue at the position corresponding to position 11 in SEQ ID NO: 4-7 has been mutated to an amino acid selected from the group consisting of glutamic acid, lysine, tyrosine, threonine, phenylalanine, leucine, isoleucine, tryptophan, methionine, valine, alanine, histidine and arginine.

Abstract: A combined administration of a liposomal composition comprising Eribulin or a pharmaceutically acceptable salt thereof and a PD-1 antagonist exhibits unexpected antitumor effect.

Abstract: The invention relates to a recombinant adeno-associated virus (AAV) capsid protein, which is a hybrid between AAV serotype 9 (AAV9) and AAV serotype 74 (AAVrh74) capsid proteins, wherein said recombinant hybrid AAV capsid protein has a reduced liver tropism compared to the parent AAV9 and AAVrh74 capsid proteins. The invention relates also to the derived hybrid AAV serotype vector particles packaging a gene of interest and their use in gene therapy, in particular for treating neuromuscular genetic diseases.

Abstract: A sintered ceramic foam that has a total porosity of greater than 60% by volume and the following phase composition, in mass percent based on the crystallized phases: 25 to 55% mullite, 20 to 65% corundum, 10 to 40% zirconia, mullite, corundum and zirconia together representing more than 80% of the mass of the crystallized phases. Also, a furnace that has a thermal insulator such ceramic foam.

Abstract: A wind farm/park having a plurality of spatially distributed wind turbines, including at least one upstream wind turbine and at least one downstream wind turbine. Each wind turbine includes a rotor with at least two blades. At least one downstream wind turbine is affected under certain wind conditions by a wake region generated by the upstream wind turbine and containing helical vortex structures formed at the tip of the blades of the upstream wind turbine. A geometry or configuration of one or more of the rotor blades of the upstream wind turbine is different from a geometry or configuration of the other blade(s) of the upstream wind turbine thereby creating a fixed asymmetry in the blade configuration so as to accelerate destruction of vortices in the wake of the rotor of the upstream wind turbine by exciting a natural instability of the blade tip vortices.

Abstract: Calibration techniques for devices of analog processors to remove time-dependent biases are described. Devices in an analog processor exhibit a noise spectrum that spans a wide range of frequencies, characterized by 1/f spectrum. Offset parameters are determined assuming only a given power spectral density. The algorithm determines a model for a measurable quantity of a device in an analog processor associated with a noise process and an offset parameter, determines the form of the spectral density of the noise process, approximates the noise spectrum by a discrete distribution via the digital processor, constructs a probability distribution of the noise process based on the discrete distribution and evaluates the probability distribution to determine optimized parameter settings to enhance computational efficiency.

Abstract: The invention relates to a method of operating a node of a power distribution system in an optimised manner so as to minimise transmission losses on an external power bus. A power generator feeds in electrical energy via an inverter capable of carrying out Volt/VAR control under the command of an optimiser associated with a supervised learning model such as a support vector machine. This optimisation takes place in two distinct training phases, one in which the supervised learning model is trained, another in which optimal control parameters for the inverter are obtained.

Abstract: Orthopedic device caddies and kits including orthopedic device caddies. In one example, the orthopedic device caddy includes a caddy body, an elongated opening extending into the caddy body including an alignment portion and an orthopedic device retention portion. The orthopedic device retention portion of the elongated opening holds an orthopedic device having an orthopedic device engagement feature. The alignment portion of the elongated opening aligns an instrument engagement feature of an orthopedic instrument relative to the orthopedic device engagement feature.

Abstract: Systems, methods, and computer-readable storage media for protecting data. One system includes one or more processing circuits comprising memory and processors configured to receive a portion of entity data from a user device via an application programming interface (API). The processors further configured to tokenize and extract content of the portion of the entity data into a plurality of tokens. The processors further configured to generate a unique identifier for each of the plurality of tokens. The processors further configured to store a mapping between the unique identifier and each of the plurality of tokens. The processors further configured to populate, from each of the plurality of tokens, a plurality of fields of a data object associated with a security posture based on the extracted content of the portion of entity data stored in each of the plurality of tokens.

Abstract: Activity-inducible fusion proteins whose activity is post-translationally regulated utilizing a hsp90 binding domain and a drug molecule are described. In the absence of the drug molecule, the activity-inducible fusion proteins are inactivated but can be activated by a relevant physiological parameter in the presence of the drug molecule. Examples of the activity-inducible fusion proteins include chimeric antigen receptors (CAR) wherein the relevant physiological parameter is antigen binding.