Abstract: A motor vehicle exhaust line includes a hot pipe, and a cold pipe for exhaust gases. A mechanical decoupling element connects a downstream end of the hot pipe to an upstream end of the cold pipe. The exhaust line also includes a nitrogen oxide treatment device and an injector intended to reinject a reagent into, or to produce a reagent in the exhaust line upstream of the nitrogen oxide treatment device. The exhaust line includes a mixer intended to mix the exhaust gases and the reagent injected or produced by the injector. The mixer is positioned upstream of the nitrogen oxide treatment device. The nitrogen oxide treatment device is disposed in the cold pipe downstream of the mechanical decoupling element. The injector and the mixer form an assembly connected directly to the mechanical decoupling element.

Abstract: A process for drilling cavities in subterranean formations includes a step of removal of the drill cuttings using an aqueous fluid in the form of a foam, obtained by mixing: an aqueous composition (Ci) including, per 100% by weight: from 0.5% by weight to 25% by weight of a compound of formula (I): R1—C(O)—NH—CH(COOM)-(CH2)n—COOM? (I) in which n represents an integer equal to 1 or 2, R1 represents a linear or branched, saturated or unsaturated aliphatic hydrocarbon-based radical including from eight to eighteen carbon atoms, M represents a monovalent cation and M?, which is identical to or different from M, represents a hydrogen atom or a monovalent cation; or of a mixture of compounds of formula (I), and from 75% to 99.5% by weight of water, with a gas or a mixture of gases, chosen from air, nitrogen or carbon dioxide.

Abstract: The invention provides a method for selecting pharmaceutical compounds that enhance inhibition of mevalonate synthesis in which mesodermal stem cells (MSC type) that are derived from human pluripotent cells or from induced stem cell are contacted with pharmaceutical compounds to be tested in the presence of an inhibitor of mevalonate synthesis. Pharmaceutical compounds are then identified which enhance cell toxicity in the presence of the inhibitors.

Abstract: The invention provides crystalline forms of biphenyl-2-ylcarbamic acid 1-(2-{[4-(4-carbamoylpiperidin-1-ylmethyl)benzoyl]methylamino}ethyl)piperidin-4-yl ester, and pharmaceutically acceptable solvates thereof. The crystalline form can be a freebase, or a salt such as a diphosphate, monosulfate or dioxalate salt. The invention also provides pharmaceutical compositions comprising these crystalline compounds or prepared using these compounds; processes and intermediates for preparing the crystalline compounds; and methods of using these compounds to treat a pulmonary disorder.

Abstract: The present invention relates to anti-Axl antibodies and uses thereof in diagnostic and therapeutic methods. More particularly, the present invention relates to a monoclonal antibody having specificity for Axl comprising an heavy chain variable region comprising SEQ ID NO:2 in the H-CDR1 region, SEQ ID NO:3 in the H-CDR2 region and SEQ ID NO:4 in the H-CDR3 region; and a light chain variable region comprising SEQ ID NO: 6 in the L-CDR1 region, SEQ ID NO:7 in the L-CDR2 region and SEQ ID NO:8 in the L-CDR3 region. Said monoclonal antibody binds to the extracellular domain of Axl via, SEQ ID NO:9, SEQ ID NO: 10 and SEQ ID NO: 11.

Abstract: A naphthopyran compound represented by the formula (I): wherein: n1, n2, p, q is an integer comprised from 0 to 5 inclusive; m is an integer comprised from 0 to 4 inclusive; R1 and R2 represent a group selected from halogen, —Ra, —OH, —ORa, —SH, —SRa, —NH2, —NRaRa1, —NRbRc, —CO—Ra, and —CO2Ra1, wherein Ra, Ra1, Rb and Rc, are as defined in the description; R3 represents a group selected from halogen, —Ra, —OH, —ORa, —SH, —SRa, —NH2, and —NRaRa1; R4 represents a group selected from halogen, —Ra, —OH, —ORa, —SH, —SRa, —NH2, —NRaRa1, —CO—Ra, and —CO2Ra1; R5 represents a group selected from: halogen, —Ra, —OH, —ORa, —SH, —SRa, —NH2, and —NRaRa1, wherein Ra and Ra1 are as defined hereinbefore, or when q is equal to 2, then two R5 together represent further a group —O—(CH2)q1—O— wherein q1 represents an integer comprised from 1 to 3 inclusive.

Abstract: The present invention pertains to a method for producing a colloidal suspension of zirconia particles, including successively subjecting a mixture of zirconium oxychloride and an alkali metal halide in an aqueous solvent to hydrothermal treatment at a temperature above 150° C, separating the slurry obtained from the supernatant, and peptizing said slurry by adding a strong acid thereto, and desalting said slurry, for example by ultrafiltration, so as to form a colloidal suspension of zirconia. The present invention also pertains to the transparent colloidal suspension obtainable by this method, and to an optical article, such as an ophthalmic lens, comprising a transparent polymer substrate and at least one coating prepared from a composition comprising said colloidal suspension.

Abstract: The invention provides crystalline salt forms of 4?-{2-ethoxy-4-ethyl-5-[((S)-2-mercapto-4-methylpentanoylamino)methyl]-imidazol-1-ylmethyl}-3?-fluorobiphenyl-2-carboxylic acid. This invention also provides pharmaceutical compositions comprising the crystalline compounds, processes and intermediates for preparing the crystalline compounds, and methods of using the crystalline compounds to treat diseases such as hypertension.

Abstract: The present invention relates to recombinant microorganisms comprising an isobutanol producing metabolic pathway and methods of using said recombinant microorganisms to produce isobutanol. In various aspects of the invention, the recombinant microorganisms may comprise one or more modifications resulting in the reduction in the expression and/or activity of an endogenous transporter protein. In various embodiments described herein, the recombinant microorganisms may be microorganisms of the Saccharomyces clade, Crabtree-negative yeast microorganisms, Crabtree-positive yeast microorganisms, post-WGD (whole genome duplication) yeast microorganisms, pre-WGD (whole genome duplication) yeast microorganisms, and non-fermenting yeast microorganisms.

Abstract: The present invention relates to a high-voltage battery charging simulation system that includes a simulation high-voltage battery pack, a simulation battery management system, a multi-party communication device, and a charging station. The voltage of the simulation high-voltage battery pack can be calculated and updated immediately by the simulation battery management system to simulate the feature of real battery pack, so that it can detect the operation of the multi-party communication device and the charging station.

Abstract: A method is provided for demodulating a signal carrying a message transmitted by a terrestrial beacon, executed by a system comprising a constellation of satellites suitable for detecting said signal and for repeating it towards receiving stations on the ground, and an analysis module suitable for receiving signals from said stations. Each receiving station transmits the signals that it receives from the satellite to the analysis module, said module realigning said signals in frequency and/or in time relative to one another, combining the realigned signals to generate a synthetic signal having an enhanced signal-to-noise ratio, and determining the content of said message and/or the modulation parameters of said synthetic signal. The method applies notably to the accurate and reliable location of distress beacons by a satellite system.

Abstract: A boring and facing head, rotatively driven by the mandrel of a machine tool, with a turning tool mounted on a mounting slide, which may be controllably driven transversely of the axis (X) of the head body by a threaded shaft (12) operatively connected to a cylinder body (11), integral with a mandrel (4) and rotatably housing a ring gear (17), operatively connected to a gear wheel (19), driven by a controllable motor (8) and wherein the ring gear (17) comprises a circumferential tooth arrangement engaging with a gear wheel (52), integral with the driving shaft (12).

Abstract: A computer system for accessing confidential data via at least one remote unit (4), the data being stored in a secured centralized computer system (3) including elements for processing data intended for producing results, a computer connection (2) being established between the unit and the computer element, the unit being a microcomputer operating under the dependency of a local operating system. The computer connection is an encrypted tunnel connection over a public network, the unit only supporting remote administration, the unit not being operable if the computer connection is not established and, during the access thereof to the data, the unit only receiving display information associated with the process performed on the data and produced by the centralized computer system, the microcomputer of the remote unit also including an electronic encryption circuit, the operating system and the information required for the operation of the unit being stored in encrypted form.

Abstract: The invention provides a crystalline hydrochloride salt of 4-[2-(2,4,6-trifluorophenoxymethyl)phenyl]piperidine. This invention also provides pharmaceutical compositions comprising the crystalline salt, processes and intermediates for preparing the crystalline salt, and methods of using the crystalline salt to treat diseases.

Abstract: A formulation for the preparation of a wiping blade element for a vehicle windscreen wiper blade is disclosed. The formulation has an elastomer material based on chloroprene rubber in which plasticizing additives are incorporated, where the plasticizing additives include a combination of at least a first additive, the pour point of which is less than ?50° C., and at least a second additive, the pour point of which is greater than ?50° C. The first additive is octyl sebacate in a proportion of 4 phr and the second is a naphthalic oil plasticizer or a C18-C30 tricarboxylic ester in a proportion of 10 phr.

Abstract: A method for preparing a vaccine composition to be implemented in a locally administered treatment for avian viral disease, includes at least the step of: a) extemporaneously mixing a vaccine, including at least one live virus selected from a virus belonging to one or more strains of the avian disease, with an adjuvant diluent (DA), characterized in that the adjuvant diluent is a continuous aqueous phase oil-in-water emulsion or oil-in-water microemulsion.

Abstract: A shockwave generator pre-treats one or more production zones within a well to facilitate recovery of liquid and gaseous hydrocarbons from the well. The well may be heated to a particular temperature, where after a cooling agent is introduced through the shockwave generator which effects a cooling action in the walls of the well and induces cracking which is propagated by the tremors or shocks of the cooling agent as it exits the generator. The initiated cracks may be further propagated using one or more additional stimulation methods, including a freeze-thaw method which is implemented through a subsystem having overlapping components with the shockwave generator subsystem.

Abstract: A copolymer that includes for 100 mol %: a) more than 70 mol % and up to 99.9 mol % of hydrophobic monomer units (A) from stearyl methacrylate; and b) 0.1 mol % to 30 mol % of monomer units (B) from at least one monomer of a compound of formula (I) where R1 is a linear or branched alkyl radical comprising 12 to 22 carbon atoms, R2 is a hydrogen atom or a methyl radical, and n is an integer greater than or equal to 0 and lower than or equal to 30, wherein it is understood that said compound of formula (I) is not stearyl methacrylate. The invention also relates to a method for preparing and using same as a modifier of the rheology of the oil phase of a topical cosmetic, dermopharmaceutical, or pharmaceutical composition.

Abstract: A propulsion system of a spacecraft comprises a main tank adapted to contain a volume of propellant and a pressurizing gas which applies pressure to the propellant. The main tank comprises a membrane delimiting an upper volume to contain the pressurizing gas and an inferior volume to contain the propellant, the gas applying the pressure to the propellant by means of the membrane. A pressurization circuit is connected directly to the main tank. The propulsion system further comprises an auxiliary tank adapted to contain pressurizing gas. The auxiliary tank is connected directly to the main tank by means of the pressurization circuit. When in operation, gas contained in the auxiliary tank expands continuously with the gas contained in the upper volume of the main tank, the pressures prevailing in the upper volume of the main tank, in the pressurization circuit and in the auxiliary tank being identical.

Abstract: The invention relates to a windscreen wiper system, particularly for a motor vehicle. The system comprises a wiper blade (4) hinged to a drive arm (1) via an adaptor (2) connected to the arm (1) and to a hydraulic connector (3), which in turn is connected to the blade (4) and comprises at least one inlet coupling (6) designed to be coupled to a cleaning and de-icing fluid feed (5). The system also comprises a rigid joining part (7, 8), one end of which is coupled to the inlet coupling (6), and the other end of which is intended to be coupled to the fluid feed (5). In this way, the connection between the fluid feed (5) and the connector is made secure and reliable. In addition, the joining part provides an offset which makes connecting and disconnecting easier for the user, particularly when the user wishes to change a worn blade, and enables the whole of the connection to be concealed more easily and then given a more attractive appearance.