Abstract: The invention relates to antigen peptide derived from the Nectin4 and its use for preventing and treating cancer.

Abstract: A connecting adjustment assembly for a fall protection assembly including a back plate assembly and a sliding engagement member is provided. The back plate assembly includes a body and a roller. The body has a first side and an opposed second side. The body further has a first edge and an opposed second edge that defines the length of the body. The body also has a third edge and an opposed fourth edge that defines a width of the body. The body still further has a groove in the second side that passes along the width of the body. The roller is rotationally coupled proximate the second edge of the body. The sliding engagement member includes a first portion with a first post and a second portion with a connection head. The first post is configured and arranged to be at least partially received within the groove of the body.

Abstract: A cable connector assembly comprises a first stop, a second stop, and a connector. The first stop is configured and arranged to receive a first end of a cable, and the second stop is configured and arranged to receive a second end of the cable. The connector is configured and arranged to pivotally interconnect the first stop and the second stop.

Abstract: This invention provides novel compounds and the novel compounds for use as a medicine, more in particular for the prevention or treatment of neurodegenerative disorders, more specifically certain neurological disorders, such as disorders collectively known as tauopathies, and disorders characterised by cytotoxic ?-synuclein amyloidogenesis. The present invention also relates to the use of said novel compounds for the manufacture of medicaments useful for treating such neurodegenerative disorders. The present invention further relates to pharmaceutical compositions including said novel compounds and to methods for the preparation of said novel compounds. The compounds have the formula (A1) wherein R1, R2, R4, R6, E, n, Y1, Y2, Y3, Y4, Y5, L, B, R8, and m are as defined in the claims.

Abstract: A temperature-regulating valve comprises a valve body, two circlips, two small O-rings and a valve core, wherein the valve core is located in the chamber of the valve body and comprises a big retainer ring, an end cap, medium retainer ring, a big O-ring, a restraint block, a thermal component, a compression spring, small retainer ring, a slide block, a return spring and a release pressure plate.

Abstract: A personal care photoprotective composition is provided having a UV-A and UV-B sunscreen in conjunction with a tricyclodecane amide. The tricyclodecane amide functions to boost UV-A, UV-B and SPF performance when the personal care composition is applied to skin or hair of the human body.

Abstract: A method of manufacture of an anhydrous cosmetic composition comprising the mixing of dried calcium chloride with liquid carrier material and fragrance comprising a solvent to give a give a base composition, followed by the gassing of the base composition with a propellant to give an aerosol composition, wherein the fragrance and the solvent therein are pre-mixed and this mixture comprises one or more components having a log P of greater than 5.5 and a vapour pressure at 25° C. of less than 0.001 mm Hg (0.1333 Pa) and does not comprise dipropyleneglycol at 3% or greater of this mixture; the method enhancing the homogeneity and stability of the composition.

Abstract: The present invention provides a process for the manufacture of a frozen confection with a peelable coating comprising the steps of: a) Providing a frozen confection core; and b) Dipping the frozen confection core in liquid nitrogen and then applying a coating material comprising a chemically setting gelling biopolymer to the frozen confection core, wherein a second material comprising a source of divalent cations is applied to the product between steps a) and b) or after step b).

Abstract: A capsule for use in a brewing device is provided, the capsule comprising: a body part, which defines a cavity, a lid which is attached to the body part and which closes the cavity, the lid having lines of weakness which define an opening region having an area of from 75 mm2 to 300 mm2; and tea material enclosed within the cavity, wherein at least 75% by weight of the tea material particles have a size of from 2 to 10 mm. A method of preparing a tea-based beverage in a brewing device using the capsule is also provided.

Abstract: An electric vehicle and a power system and a motor controller for an electric vehicle are provided. The power system includes a power battery; a charging-discharging socket; a bidirectional DC/DC module connected with the power battery; a driving control switch connected with the power battery and the bidirectional DC/DC module; a bidirectional DC/AC module connected with the driving control switch and the power battery; a motor control switch connected with the bidirectional DC/AC module and a motor; a charging-discharging control module connected with the bidirectional DC/AC module and the charging-discharging socket; and a controller module connected with and configured to control the driving control switch, the motor control switch and the charging-discharging control module according to a current operation mode of the power system.

Abstract: A plasmonic structure comprises a substrate and an electro conductor provided in or on the substrate. The electro conductor comprises a first part configured to provide a first series of plasmon resonance modes (for incident radiation of a first wavelength) and a second part configured to provide a second series of plasmon resonance modes (for incident radiation of a second wavelength). The first and second parts are functionally connected in a linkage region, wherein the electro conductor is shaped such as to form a capacitive gap. The electro conductor is further configured to direct radiation incident on the plasmonic structure of the first wavelength predominantly toward a first direction and to direct radiation incident on the plasmonic structure of the second wavelength predominantly toward a second direction, in which the first direction and the second direction are separated by an angle of at least 60°.

Abstract: A machining method for machining a surface of a spectacle lens at a fixed rotation speed, includes a step of determining the rotation speed from geometric characteristics of the surface, characterized in that the step of determining the rotation speed includes the following steps: a value (Maxdiff) representative of the largest difference in geometric value of the mean sphere on the surface is determined; and the rotation speed is deduced from the value (Maxdiff) of the largest difference in geometric values of the mean sphere on the surface and from a geometric value of the cylinder (FV torus) at a predetermined far-vision control point.

Abstract: The invention provides compounds of formula (I): wherein the variables are defined in the specification, or a pharmaceutically-acceptable salt thereof, that are inhibitors of replication of the hepatitis C virus. The invention also provides pharmaceutical compositions comprising such compounds, methods of using such compounds to treat hepatitis C viral infections, and processes and intermediates useful for preparing such compounds.

Abstract: A method of manufacturing a high-voltage electrical insulator (1), having at least one metal insulator element (4, 6) cemented to a dielectric insulator element (2) by a cement mortar (5), includes at least one of the following steps: preparing the cement mortar (5) from aluminous cement and sand that are mixed with at least water; assembling the dielectric element (2) with the metal element (4, 6), the mortar (5) being placed between the dielectric insulator element (2) and the metal element (4, 6); and vibrating the dielectric element (2) and the metal element (4, 6) as assembled together, so as to distribute the mortar (5) between the dielectric element and the metal element (2, 4, 6). In order to prepare the mortar (5), an active ingredient of the polymer superplasticizer type based on polyglycol methacrylic acid ester is added, and the vibrating is performed for a duration lying in the range 2 seconds to 20 seconds, and preferably in the range 4 seconds to 15 seconds.

Abstract: A binocular multiplexing device for a single-channel ophthalmological instrument for objective measurement of at least one vision parameter of a subject, the ophthalmological instrument including elements for generating a single light beam, elements for collecting a measurement beam by reflecting and/or refracting the light beam against the subject's eye and a sensor associated with the single measurement channel.

Abstract: There is provided a System and method of wavefront compensation in a synthetic aperture imaging system. A return signal data representative of a signal reflected by a target area to be imaged is received. A compensation phase figure corresponding to a wavefront compensation to be applied is provided. The compensation phase figure is added or otherwise applied to the phase pattern of the return signal data in order to obtain a compensated phase pattern. An optical beam is spatially modulated according to the compensated phase pattern to produce a modulated optical beam such that the compensation phase figure produces a wavefront compensation on the optical beam. An image of the target area is optically generated using the modulated optical beam.

Abstract: An electric vehicle running control system is provided. The electric vehicle running control system comprises a heating circuit coupled with an in-vehicle battery and configured to heat the in-vehicle battery. The vehicle running control system further comprises a load capacitor and a first current storage element. The first current storage element may be coupled with the load capacitor and the heating circuit respectively configured to reduce interference between the heating circuit and the load capacitor.

Abstract: A modular lavatory monument assembly configured to be positioned in the interior of an aircraft. The modular lavatory monument assembly includes first, second, third and fourth walls that cooperate to form an outer shell that defines a lavatory interior. The fourth wall includes an alcove extending outwardly therefrom. The assembly also includes a sink module positioned in the alcove, a mirror module positioned above the sink module in the alcove, and a door positioned on one of the second or third walls.

Abstract: An uncooled microbolometer detector that includes a substrate, a platform held above the substrate by a support structure, at least one thermistor provided on the platform, and an optical absorber. The optical absorber includes at least one electrically conductive layer extending on the platform over and in thermal contact with the at least one thermistor and patterned to form a resonant structure defining an absorption spectrum of the uncooled microbolometer detector. The optical absorber is exposed to electromagnetic radiation and absorbs the electromagnetic radiation according to the absorption spectrum. A microbolometer array including a plurality of uncooled microbolometer detectors arranged in a two-dimensional array is also provided. Advantageously, these embodiments allow extending the absorption spectrum of conventional infrared uncooled microbolometer detectors to the terahertz region of the electromagnetic spectrum.