Abstract: The present invention provides a process for preparing a vegetarian burger comprising the step of mixing hydrated TVP pieces with methyl cellulose, plant protein concentrate, fat, water and defibrillated hydrated texturized fibrous vegetable protein material to produce a vegetarian dough.

Abstract: The techniques described herein relate to methods and apparatuses for firearm fire control mechanisms. The firearm includes a safety bar configured to engage with a safety selector and with a trigger and to transition between a first safety configuration and a second safety configuration, and a sear configured to engage with the trigger and to transition between a first sear configuration and a second sear configuration, wherein in the first sear configuration, the sear or trigger is engaged with a hammer to prevent the hammer from being released to fire the firearm, and in the second sear configuration, the sear does not prevent the hammer from being released to fire the firearm.

Abstract: [Problem] To improve operator convenience in controlling the ON/OFF states of a plurality of wireless speakers. [Solution] A wireless speaker 1, when instructed through a power button or by a controller 2 to transition to an ON state, causes said wireless speaker 1 itself to transition to an ON state and also transmits a command for ON state transition to each of other wireless speakers 1 belonging to the same group as said wireless speaker 1. When instructed to transition to an OFF state, said wireless speaker 1 transmits a command for OFF state transition to each of the other wireless speakers 1 belonging to the same group as said wireless speaker 1, and also transitions to the OFF state. If an ON state transition command has been received from another wireless speaker 1, then the wireless speaker 1 transitions to the ON state, and if an OFF state transition command has been received, then the wireless speaker 1 transitions to the OFF state.

Abstract: Aspects of the invention described herein relate to methods of making and using inducible promoters for transgene expression. The inducible promoters are derived from the NFAT-RE inducible system and are used to improve or enhance T cell survival and proliferation.

Abstract: The invention concerns a process to convert di-rhamnolipid to mono-rhamnolipid, using an ?-L-rhamnosidase enzyme which has a sequence identity of at least 70% with either SEQ ID. 1 or SEQ. ID 2.

Abstract: Provided herein are bifunctional compounds that bind tau protein and/or promote targeted ubiquitination for the degradation of tau protein. In particular, provided are compounds that can bind tau protein, a protein whose aggregation is implicated in a variety of neurodegenerative disease (e.g., tauopathies), and can promote its degradation by recruiting an E3 ubiquitin ligase (e.g., Cereblon), which can ubiquitinate tau protein, marking it for proteasomal degradation. Also provided are radiolabeled forms of the bifunctional compounds, pharmaceutical compositions comprising the bifunctional compounds, methods of detecting and/or diagnosing neurological disorders, methods of detecting and/or diagnosing pathological aggregation of tau protein (e.g., in the central nervous system), methods of treating and/or preventing neurological disorders, and methods of promoting the degradation of tau protein by E3 ubiquitin ligase activity in a subject by administering a compound or composition described herein.

Abstract: A lost circulation detection device includes a first detection member and a second detection member, a first signal transmitter and a first signal receiver are disposed on the first detection member, and the first signal transmitter transmits a signal along an axial direction of a rockshaft so that the first signal receiver acquires data information of drilling fluid in the axial direction of the rockshaft; a fluid channel penetrating through the second detection member is disposed in the second detection member, and the fluid channel is configurable to be in communication with the rockshaft; a second signal transmitter and a second signal receiver are disposed oppositely on two sides of the fluid channel, and the second signal transmitter transmits a signal along a center line of a second accommodating groove, so that the second signal receiver acquires data information of drilling fluid in a circumferential direction of the rockshaft.

Abstract: An orthopedic walker is disclosed that improves comfort and shock absorption during use by incorporating a flexure zone that deflects to ease the forces caused by the heel strike portion of a patient's gait. The flexure zone is created by cutting around the heel on the bottom of the sole to allow for the heel portion to flex. The exterior shell of the walker is may be made of a formable resilient material that when combined with an attached tongue structure reduces a volume of encapsulation of the lower limb. The shell encloses a padding on the inner side that may take the form of air/bladders and/or foam, and tabs on each side selectively engage receiving tabs on the inside lateral and medial side of the base upright portions. A separate tongue structure is used to enclose the foot and is made adjustable using various methods such as slits and novel connectors.

Abstract: The present invention concerns a compound of following general formula (I): where: either R is an R1 group and R? is an -A1-Cy1 group, or R is an -A1-Cy1 group and R? is an R1 group, R1 particularly being H or (C1-C6)alkyl group; A1 being an —NH— radical or —NH—CH2— radical; Cy1 particularly being a phenyl group, A is a fused (hetero)aromatic ring having 5 to 7 atoms, for use for treating cancer.

Abstract: A device fastens a tank for pressurized gas, such as hydrogen, to a frame. The tank comprises a base including a cylindrical seat. The device comprises a fastener able to clamp the cylindrical seat of the base, where the device also comprises at least one mechanical fuse that is able to break in case of impact experienced by the frame, so that the device releases the base from the frame.

Abstract: The present invention relates to the technical field of medicine, and particularly to a lycorine derivative of Formula (I), and a pharmaceutically acceptable salt, a preparation method, a pharmaceutical composition and use thereof. The lycorine derivative has obvious antiviral activity and is useful in the treatment of viral diseases such as hand-foot-mouth disease.

Abstract: A pressurized gas tank comprises at least two cylinders and a rail capable of fluidly connecting the at least two cylinders. At least one cylinder includes a base for connection to the rail. The rail includes at least one reception area of a shape substantially complementary to a shape of the base. The base has a shape substantially revolutionary about a first axis and comprises a number at least equal to n of angularly equidistant tapped holes. The at least one reception area comprises a number equal to n of ports, in the form of an arc of a circle, angularly equidistant, of width substantially equal, by greater value, to a diameter of a tapped hole and of angular extent substantially equal to 360°/n.

Abstract: The invention provides substituted pyrazolo[1,5-a]pyrimidine and related organic compounds, compositions containing such compounds, medical kits, and methods for using such compounds and compositions to treat medical disorders, e.g., Gaucher disease, Parkinson's disease, Lewy body disease, dementia, or multiple system atrophy, in a patient. Exemplary substituted pyrazolo[1,5-a]pyrimidine compounds described herein include 5,7-dimethyl-N-phenylpyrazolo[1,5-a]pyrimidine-3-carboxamide compounds and variants thereof.

Abstract: An insulated tuckstone that includes a basic tuckstone and an insulating layer exhibiting a thermal conductivity lower than 2.0 W·m 1·K?1 between 20° C. and 500° C., exhibiting enough rigidity to be self-supporting and covering an insulated surface of the basic tuckstone. The insulated surface is included in the lower surface of the basic tuckstone, extending into the lower transition surface and representing more than 20% of the lower transition surface. The insulating layer has a chemical composition, as a percentage by mass on the basis of the oxides, such that Al2O3+SiO2+ZrO2+CaO+Na2O+MgO+K2O+TiO2+Fe2O3+HfO2+P2O5+Y2O3>80%.

Abstract: Methods for management of encoding complexity for image and video encoding, for example for algorithms belonging to the JPEG 2000 family of standards, where the encoding process targets a given compressed size (i.e. a total coded length) for the image or for each frame of a video sequence. Described are a set of methods for complexity constrained encoding of HTJ2K code-streams, involving collection of local or global statistics for each sub-band (not for each code-block), generation of forecasts for the statistics of sub-band samples that have not yet been produced by spatial transformation and quantization processes, and the use of this information to generate a global quantization parameter, from which the coarsest bit-plane to generate in each code-block can be deduced. Coded length estimates can be generated in a manner that enables latency and memory to be separately optimized against encoded image quality, while maintaining low computational complexity.

Abstract: A cutting tool includes a base with a table surface and a cutting platform. The cutting platform is suspended above the table surface and includes a blade housing. The blade housing includes a blade holder with a linear blade. The blade holder is slidably connected through the base housing. A housing column is configured on the base of the cutting tool. A handle raises and lowers the blade. A guide rail is pivotally connected to the table surface by at least one releasable guide rail connector. The guide rail is releasably locked with respect to the blade at a plurality of angles.

Abstract: Optical assemblies having a barrel and one or more optical elements mounted therein are provided. The optical assembly includes a resilient spacer positioned between two consecutive ones of the components mounted in the barrel. In typical implementations, the contacting surface of either one of the components adjacent to the resilient spacer is precisely centered relative to the center axis of the cavity of the barrel. Furthermore, an outwardly-directed resulting force is applied to the resilient spacer by its engagements with the adjacent components.

Abstract: A method and a system for detection and synthetic aperture (SA) imaging of a target are disclosed. The method may include illuminating a scene with a search signal transmitted from a moving platform, receiving a search return signal from a target present in the scene, and estimating, from the search return signal, the range and the angular location of the target. The method may also include generating an SA transmission signal and a local oscillator (LO) signal with a time delay therebetween based on the estimated range, and illuminating the scene with the SA transmission signal pointed along an imaging direction based on the estimated angular location of the target. The method may further include receiving an SA return signal from the target, mixing the SA return signal with the LO signal to generate SA signal data, and generating an SA image of the target from the SA signal data.

Abstract: A rifle has a fixed main body, including a barrel, a receiver with an upper opening, and a breech element. A trigger group is at least partially housed in the receiver, including a trigger, a hammer device operable by the trigger, and a safety member positionable in a shooting position, disengaged from the hammer device and in a safety position, engaged with and blocking the hammer device. A carriage assembly with a shutter group is positioned on the receiver at the upper opening and axially movable by the user between an advanced shooting configuration and a retracted rearming configuration. The carriage assembly includes a safety group controllable by the user, with the carriage assembly in the advanced configuration, in a ready-to-shoot configuration, in which it is disengaged from the safety member, and a safety configuration, in which it engages and keeps the safety member in the safety position.

Abstract: The present invention is in the field of antiperspirant compositions, in particular, compositions comprising antiperspirant actives. Disclosed is an anhydrous antiperspirant composition comprising (i) 4 to 30% of one or more saturated fatty acid with 14-26 carbons by weight of the composition; (ii) an organic compound selected from alcohols with 8-24 carbons, alkanes with 7-20 carbons, alkyl or alkyl-aryl esters, glyceryl esters, sorbitan esters, ethoxylated sorbitan esters, and a mixture thereof; (iii) 5 to 80% of ethanol by weight of the composition; and (iv) a cosmetically acceptable carrier; wherein said saturated fatty acid is selected from myristic acid, palmitic acid, stearic acid, arachidic acid, behenic acid, lignoceric acid, cerotic acid and 12-Hydroxystearic acid. Also disclosed is a method of reducing perspiration comprising a step of topical application of the anhydrous antiperspirant composition.