Patents Assigned to D
  • Well cementing method for improving well cementing quality by controlling hydration heat of cement slurry
    Patent number: 11926787
    Abstract: A well cementing method is described for improving cementing quality by controlling the hydration heat of cement slurry. By controlling the degree and/or rate of hydration heat release from cement slurry, the method improves the hydration heat release during formation of cement with curing of cement slurry, improves the binding quality between the cement and the interfaces, and in turn improves the cementing quality at the open hole section and/or the overlap section. The cementing method improves cementing quality of oil and gas wells and reduces the risk of annular pressure.
    Type: Grant
    Filed: April 21, 2020
    Date of Patent: March 12, 2024
    Assignees: PetroChina Company Limited, CNPC Engineering Technology R&D Company Limited
    Inventors: Shuoqiong Liu, Hua Zhang, Jianzhou Jin, Ming Xu, Yongjin Yu, Fengzhong Qi, Congfeng Qu, Hong Yue, Youcheng Zheng, Wei Li, Yong Ma, Youzhi Zheng, Zhao Huang, Jinping Yuan, Zhiwei Ding, Chongfeng Zhou, Chi Zhang, Zishuai Liu, Hongfei Ji, Yuchao Guo, Xiujian Xia, Yong Li, Jiyun Shen, Huiting Liu, Yusi Feng, Bin Lyu
  • Devices and methods for the characterization of the 3D orientation of light emitting dipoles
    Patent number: 11927737
    Abstract: The disclosure may relate to a method for the characterization of the 3D orientation of an emitting dipole within a specimen. The method comprises splitting a light beam emitted by the emitting dipole and exiting an objective lens into a first and a second beams; spatially filtering said first beam by using a spatial frequency filter; splitting each of said filtered first beam and said second beam into two beams linearly polarized using polarizing beam splitters; detecting with an optical detection unit four beams linearly polarized in a detection plane optically conjugated with the front focal plane of said microscope objective lens; determining, from four intensity images, in a predefined frame of the specimen, the mean orientation and the angular aperture of the distribution of the 3D orientation of the emitting dipole, during an acquisition time of said four intensity images.
    Type: Grant
    Filed: September 28, 2020
    Date of Patent: March 12, 2024
    Assignees: Université d'Aix-Marseille, Centre National de la Recherche Scientifique, CENTRALE MARSEILLE
    Inventors: Sophie Brasselet, Valentina Curcio
  • Trochoidal display mechanism
    Patent number: 11927918
    Abstract: The invention relates to a mechanism for displaying an information for a timepiece, comprising a mobile (10) intended to be driven in rotation by the movement of the timepiece about a display axis (17), a satellite (20) pivoted on the mobile (10) about a satellite axis (27) parallel to the display axis (17) and remote from a non-zero distance d1 thereof, a display area (80), an indicator (50) secured to the satellite (20) and the position of which relative to the display area (80) provides the information, and a crown (30) centered on the display axis (17) and kinematically connected to the satellite (20). The mechanism is particular in that the indicator (50) is located at a distance d2 from the satellite axis (27), which is greater than or equal to the distance d1.
    Type: Grant
    Filed: June 18, 2019
    Date of Patent: March 12, 2024
    Assignee: Manufacture D'Horlogerie Audemars Piguet SA
    Inventors: Gilles Rey-Mermet, Sylvain Cornibé
  • Chromatography columns, systems and methods
    Patent number: 11927573
    Abstract: The present invention relates to axial flow chromatography columns, methods for separating one or more analytes in a liquid by the use of such columns, and systems employing such columns. The column comprises a first port and a second port, the first port and said second port being at essentially the same level or elevation above the level of the bed space on the chromatography column.
    Type: Grant
    Filed: January 25, 2021
    Date of Patent: March 12, 2024
    Assignee: CYTIVA BIOPROCESS R&D AB
    Inventor: Klaus Gebauer
  • Housing for mechanical device, mechanical assembly, gear motor and associated attachment method
    Patent number: 11927259
    Abstract: A method for attaching a plastic barrel configured to guide an output shaft of a mechanical device to a housing for the mechanical device is disclosed. The housing includes a chimney delimited by an upper edge and a base, the chimney being arranged to partially surround the output shaft, the plastic barrel having a lateral protuberance. The method involves at least the following steps: inserting a first end of the plastic barrel into the chimney of the housing until the lateral protuberance axially abuts against the upper edge of the chimney, and at least partially deforming the first end of the plastic barrel in order to form an axial counter-abutment.
    Type: Grant
    Filed: March 29, 2021
    Date of Patent: March 12, 2024
    Assignee: VALEO SYSTÈMES D'ESSUYAGE
    Inventors: Alain Servin, Jean-Michel Berthome, Quentin Aubugeau
  • Certain pladienolide compounds and methods of use
    Patent number: 11926619
    Abstract: The present disclosure provides novel pladienolide compounds, pharmaceutical compositions containing such compounds, and methods for using the compounds as therapeutic agents. These compounds may be useful in the treatment of cancers, particularly cancers in which agents that target the spliceosome and mutations therein are known to be useful. Also provided herein are methods of treating cancers by administering at least one compound disclosed herein and at least one additional therapy.
    Type: Grant
    Filed: April 8, 2019
    Date of Patent: March 12, 2024
    Assignee: Eisai R & D Management Co., Ltd.
    Inventors: Gregg F. Keaney, John Wang, Baudouin Gerard, Kenzo Arai, Xiang Liu, Guo Zhu Zheng, Kazunobu Kira, Lisa A. Marcaurelle, Marta Nevalainen, Ming-Hong Hao, Morgan Welzel O'Shea, Parcharee Tivitmahaisoon, Sudeep Prajapati, Tuoping Luo, Nicholas C. Gearhart, Jason T. Lowe, Yoshihiko Kotake, Satoshi Nagao, Regina Mikie Kanada Sonobe, Masayuki Miyano, Norio Murai, Andrew Cook, Shelby Ellery, Atsushi Endo, James Palacino, Dominic Reynolds
  • Tumor-treating pharmaceutical composition
    Patent number: 11925639
    Abstract: Provided is a pharmaceutical composition for treating a tumor, which is used in combination therapy of lenvatinib and (6S,9aS)—N-benzyl-8-({6-[3-(4-ethylpiperazin-1-yl)azetidin-1-yl]pyridin-2-yl}methyl)-6-(2-fluoro-4-hydroxybenzyl)-4,7-dioxo-2-(prop-2-en-1-yl)hexahydro-2H-pyrazino[2,1-c][1,2,4]triazine-1(6H)-carboxamide.
    Type: Grant
    Filed: February 6, 2018
    Date of Patent: March 12, 2024
    Assignee: Eisai R&D Management Co., Ltd.
    Inventors: Yoichi Ozawa, Yusaku Hori, Kazuhiko Yamada, Hiroshi Kamiyama, Masahiro Matsuki
  • HYBRID AND TRUNCATED IMMUNE CELL PROTEINS
    Publication number: 20240076351
    Abstract: In Hybrid and truncated immune cell proteins are described. Hybrid proteins are stimulatory and include an extracellular domain of one stimulatory immune cell protein, an intracellular domain of a different stimulatory immune cell protein, and a transmembrane domain linking the extracellular domain to the intracellular domain. Truncated proteins include an immune cell receptor ligand and a transmembrane domain but lack a functional intracellular domain. The hybrid and truncated proteins can be used to modulate and/or diversify immune cell activation in the fight against cancers and infectious diseases, among other uses.
    Type: Application
    Filed: January 14, 2022
    Publication date: March 7, 2024
    Applicant: Seattle Children's Hospital d/b/a Seattle Children's Research Institute
    Inventor: Shannon Oda
  • Adjustable Mobile Loading Dock
    Publication number: 20240076145
    Abstract: An apparatus and related method for a dock housing for a pre-existing loading dock. The dock housing includes a base with top and bottom surfaces and front, back and opposed sidewalls. The front wall has integral fork pockets for interaction with forks on a fork truck for movement of the base into a desired location and the top surface has an opening to receive a dock leveler into such opening. Also included is a modular frame mounted onto the base in sections, the sections including a frame-front wall, opposed frame-sidewalls and a frame-top wall, the frame-front wall having a trailer-receiving opening to receive a trailer, the frame-sidewalls including a slotted-base attachment for securement of the base and sidewalls together. The dock housing is formed by securing the frame-sidewalls to a wall of a pre-existing building as well as securing the base, the frame-front wall and the frame-top wall together.
    Type: Application
    Filed: September 2, 2022
    Publication date: March 7, 2024
    Applicant: Leum Engineering, Inc. d/b/a Dockzilla Co.
    Inventors: Grant Leum, Eric Demerath, Nick Benz
  • Loading Dock with Integrated Leveler
    Publication number: 20240076147
    Abstract: A modular loading dock with a mobile base which includes two, opposing, adjustable leg members and top and bottom surfaces, the top surface having an opening to receive a dock leveler into such opening, the dock leveler includes a lower end and an upper end, the upper end abuts a preexisting structure and the lower end includes a lower edge having a lip, the lip is able to be activated between an extended/engaged position to contact a truck bed and a retracted/disengaged position. The mobile base also includes a housing with a modular frame mounted onto the base in sections, the sections include a frame-front wall, opposed frame-sidewalls and a frame-top wall, the frame-front wall has a vehicle-receiving opening to receive a back end of a vehicle.
    Type: Application
    Filed: September 2, 2022
    Publication date: March 7, 2024
    Applicant: Leum Engineering, Inc. d/b/a Dockzilla Co.
    Inventors: Grant Leum, Eric Demerath
  • Loading Dock with Integrated Leveler
    Publication number: 20240076146
    Abstract: A modular loading dock with a mobile base which includes two, opposing, adjustable leg members and top and bottom surfaces, the top surface having an opening to receive a dock leveler into such opening, the dock leveler includes a lower end and an upper end, the upper end abuts a preexisting structure and the lower end includes a lower edge having a lip, the lip is able to be activated between an extended/engaged position to contact a truck bed and a retracted/disengaged position. The mobile base also includes a housing with a modular frame mounted onto the base in sections and can receive a back end of a vehicle. The modular frame has a tensioned vinyl covering. The modular loading dock can also include an extension portion with a covering.
    Type: Application
    Filed: April 4, 2023
    Publication date: March 7, 2024
    Applicant: Leum Engineering, Inc. d/b/a Dockzilla Co.
    Inventors: Grant Leum, Eric Demerath
  • P2RX7 modulators in therapy
    Patent number: 11919854
    Abstract: The present invention relates to compounds of formula (I), their enantiomers and their pharmaceutically acceptable salts, and their use in therapy, particularly for the treatment of cancer or inflammatory diseases.
    Type: Grant
    Filed: March 29, 2019
    Date of Patent: March 5, 2024
    Assignees: CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE, CHRU DE LILLE, UNIVERSITE COTE D'AZUR, INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM), UNIVERSITE DE LILLE, JUNIA
    Inventors: Valérie Vouret, Laetitia Douguet, Alina Ghinet, Germain Homerin, Benoît Guy Marie Rigo, Davy Jérémy Baudelet, Xavier Dezitter, Régis Millet, Christophe Furman
  • Dipeptidyl peptidase-4 inhibitors for topical eye treatment of retinal neurodegenerative diseases
    Patent number: 11918577
    Abstract: The invention relates to dipeptidyl peptidase-4 inhibitors, including saxagliptin and sitagliptin, for use in the topical eye treatment and/or prevention of retinal neurodegenerative diseases, in particular diabetic retinopathy and its associated microvascular impairment. The invention also encompasses pharmaceutical topical eye compositions for use in the topical treatment and/or prevention of these diseases.
    Type: Grant
    Filed: April 29, 2021
    Date of Patent: March 5, 2024
    Assignee: FUNDACIÓ HOSPITAL UNIVERSITARI VALL D'HEBRON—INSTITUT DE RECERCA
    Inventors: Rafael Simó Canonge, Cristina Hernández Pascual
  • Resistless patterning mask
    Patent number: 11923198
    Abstract: In a first aspect, the present disclosure relates to a method for forming a patterning mask over a layer to be patterned, the method comprising: (a) providing a first layer over a substrate, the substrate comprising the layer to be patterned, the first layer being capable to bond with a monolayer comprising a compound comprising a functional group for bonding to the first layer and a removable organic group, (b) bonding the monolayer to the first layer, (c) exposing the monolayer to an energy beam, thereby forming a pattern comprising a first area comprising the compound with the removable organic group and a second area comprising the compound not having the removable organic group, and (d) selectively depositing an amorphous carbon layer on top of the first area.
    Type: Grant
    Filed: April 12, 2021
    Date of Patent: March 5, 2024
    Assignees: IMEC VZW, Katholieke Universiteit Leuven, KU LEUVEN R&D
    Inventors: Mikhail Krishtab, Silvia Armini
  • Neprilysin inhibitors
    Patent number: 11919888
    Abstract: In one aspect, the invention relates to compounds having the formula: where X, Ra, Rb, R2, and R7 are as defined in the specification, or a pharmaceutically acceptable salt thereof. These compounds are prodrugs of compounds having neprilysin inhibition activity. In another aspect, the invention relates to pharmaceutical compositions comprising these compounds; methods of using these compounds; and processes and intermediates for preparing these compounds.
    Type: Grant
    Filed: February 23, 2023
    Date of Patent: March 5, 2024
    Assignee: THERAVANCE BIOPHARMA R&D IP, LLC
    Inventors: Melissa Fleury, Adam D. Hughes
  • Method for cleaning a glazed surface of a motor vehicle
    Patent number: 11919486
    Abstract: System for cleaning a glazed surface of a motor vehicle, including at least one wiper and a drive device for driving at least the wiper along an axis of translation, substantially perpendicular to said wiper, where the glazed surface is a detection surface of a sensor/emitter of a detection assembly and in that the drive device includes at least one drive motor driving in rotation about an axis of rotation substantially perpendicular to the axis of translation, and at least a conversion device converting a rotational movement of the drive motor into a rectilinear movement along the axis of translation.
    Type: Grant
    Filed: November 12, 2020
    Date of Patent: March 5, 2024
    Assignee: Valeo Systemes d'Essuyage
    Inventors: Gerald Caillot, Frederic Giraud, Jean-Michel Jarasson, Vincent Izabel
  • Rubber composition for tyre rim cushion
    Patent number: 11920032
    Abstract: The present invention relates to a cross-linkable rubber composition, the cross-linkable rubber composition comprising a natural rubber (NR), a filler, and a resin. The resin is a terpolymer of ethylene, acrylic ester and maleic anhydride and is present in an amount ranging from ?5 to ?20 phr.
    Type: Grant
    Filed: September 26, 2019
    Date of Patent: March 5, 2024
    Assignee: Apollo Tyres Global R & D B.V.
    Inventors: Anup Mondal, Henrik Stevens, Louis Reuvekamp
  • PERSONAL CARE COMPOSITION
    Publication number: 20240065964
    Abstract: Disclosed is a personal care composition comprising a moringa seed oil and a moringa extract, wherein the amount of the moringa seed oil is less than 0.8% by weight of the composition, the amount of the moringa extract is less than 0.3% by weight of the composition, the weight ratio of the moringa seed oil to the moringa extract is in the range of 9:1 to 55:1 and the moringa seed oil is different from the moringa extract.
    Type: Application
    Filed: December 6, 2021
    Publication date: February 29, 2024
    Applicant: Conopco, Inc., d/b/a UNILEVER
    Inventors: Xuelan GU, Tingyan MI
  • METHODS AND DEVICES FOR IDENTIFYING A SPEAKER
    Publication number: 20240071393
    Abstract: Methods and devices identify a speaker by extracting speech features from at least one keyword. A speaker vector is produced by feeding the extracted speech features to a pre-trained neural network. The pre-trained neural network includes a convolutional neural network. The convolutional neural network serves as a backbone and provides a backbone embedding. The pre-trained neural network also includes a neural subnetwork. The produced speaker vector is compared with at least one of registered speaker vectors corresponding to known speakers to identify the speaker.
    Type: Application
    Filed: August 22, 2022
    Publication date: February 29, 2024
    Applicant: ID R&D INC.
    Inventors: Konstantin Konstantinovich SIMONCHIK, Rostislav Nikolaevich MAKAROV
  • Bottle for water dispensers
    Patent number: D1016611
    Type: Grant
    Filed: October 9, 2020
    Date of Patent: March 5, 2024
    Assignee: SOCIETE ANONYME DES EAUX MINERALS D'EVIAN
    Inventors: Jean-Baptiste Tanchette, Alain Colloud