Abstract: The invention provides a ghrelin molecule for use in the treatment and/or prophylaxis of Acute Heart Failure (AHF) in an individual, as well as corresponding methods and uses. The invention further provides associated compositions and kits of parts, for use in the treatment and/or prophylaxis of AHF in an individual.

Abstract: There is provided a bioabsorbable peptide tissue occluding agent that can be applied to large mammals including humans, the peptide tissue occluding agent being obtained by artificial synthesis to avoid concerns of infection by viruses and the like. The tissue occluding agent contains a peptide, wherein the peptide is an amphiphilic peptide having 8-200 amino acid residues with the hydrophilic amino acids and hydrophobic amino acids alternately bonded, and is a self-assembling peptide exhibiting a ?-structure in aqueous solution in the presence of physiological pH and/or a cation.

Abstract: Valve including a valve body with an inlet port and two outlet ports, a core capable of allowing or interrupting the flow of fluid between the inlet port and the outlet ports, the core being rotatably movable about a longitudinal axis and configured to assume two end angular positions, a gear motor comprising an output shaft driving the core, sensors for managing the electric motor mounted to a first, facing electronic board, an angular position sensor of the output shaft, mounted to a second electronic board, the first electronic board and the second electronic board being disposed in two distinct planes orthogonal to the longitudinal axis, a magnet rotatably attached to the output shaft, the position and angular extension of which are such that the magnet does not disturb the operation of the management sensors.

Abstract: Methods and systems are disclosed that enable the leveraging of financial instrument research at an individual financial instrument level but across multiple classifications of financial instruments to efficiently build an investment portfolio for an investor based on a desired portfolio objective through a plurality of graphical user interfaces (GUIs).

Abstract: A transition metal dichalcogenide transistor, comprising: a gate, a gate dielectric layer and a channel layer from bottom to top, a source/drain region are located on both the sides of the gate dielectric layer, wherein, in a plane paralleled to the channel layer, the length of the channel layer in each direction is greater than the length of the gate dielectric layer, and the length of the gate dielectric layer in each direction is greater than or equal to the length of the gate; wherein, the source/drain region are a first transition metal dichalcogenide with metallic properties, and the channel layer is a second transition metal dichalcogenide with semiconductor properties.

Abstract: A package opening knife has a body part, a blade part, a gripping part that extends in an elongated shape in a prescribed first direction, and a guide part provided with a guide surface that slides in a surface direction of the package in a state of contacting the package to guide movement of the blade part. When a surface direction of the guide is defined as a second direction, the first direction and the second direction become substantially parallel to each other.

Abstract: The present invention corresponds to the field of cancer and is related to predicting cancer detection, diagnosis, monitoring and prediction of response to treatment, in particular platelet derived-endothelial cell growth factor (PD-ECGF) levels for their use as a potential value in monitoring disease evolution and predicting response to anti-angiogenic treatment.

Abstract: A device for detecting the approach of a vortex ring state for a rotary wing aerodyne, the detection device including a set of vibration sensors configured to be distributed in or on the aerodyne, and a data processing unit configured to receive in real time measurement data from the sensors, process the data in order to calculate in real time the vibration spectrum of the aerodyne, detect in real time, by vibration analysis, the approach of a vortex ring state as a function of the calculated vibration spectrum, and issue an alarm in the event of detection of the approach of a vortex ring state.

Abstract: The use of UV-activated Copper Radical Oxidase (CRO) enzymes in the implementation of oxidation reactions. Also, a process for oxidizing organic compounds using enzymes which are activated by UV light. The process also leads to concomitant formation of hydrogen peroxide, that can optionally be used in hydrogen peroxide mediated processes. Further, the process relates to the oxidation of alcohols in aldehydes.

Abstract: Adapter (29) for a connection device (7) configured to connect a wiper blade (3) to a drive arm (5) in a wiper system (1) for a motor vehicle, comprising a first lateral wall (43) and a second lateral wall (45) distant from one another and connected to one another by an upper wall (46), the first lateral wall (4) and the second lateral wall (45) respectively comprising a first orifice (47) and a second orifice (49) which are suitable for receiving a pin (23) extending in a transverse direction (Oy) projecting from the drive arm (5), characterized in that the second lateral wall (45) comprises at least one attachment means (57) for attaching the pin (23) in the second orifice (49) configured to hold the adapter (29) secured to the drive arm (5) at least in the transverse direction (Oy).

Abstract: The present invention is directed to new stable immediate release tablet and capsule formulations for the Janus Kinase 3 (JAK3) inhibitor 1-((2S,5R)-5-((7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino)-2-methylpiperidin-1-yl)prop-2-en-1-one para-toluenesulfonate having structure

Abstract: Gamma ray and e-beam irradiation provided efficient sterilization of certain self-assembling peptides (including RADA16 in solution) without substantial degradation of the major peptide, while, e.g., another self-assembly peptide, QLEL12 was significantly degraded following irradiation. Irradiation sterilization enhances the rheological property of, for example, RADA16 hydrogel once applied to tissue at a physiological pH. The rheological property increase can result in higher efficacy in a variety of biomedical applications.

Abstract: An electrical cable connecting system includes a modular electrical or electronic wiring device assembly, in which an electrical or electronic wiring device and a connector may be electrically coupled via pig-tail jumper electrical wires. The connector may be coupled to cable electrical wires fitted with a cable protector to protect the electrical wire conductors therein. The connector may include internal electrical terminals for electrically coupling building electrical cable wires with corresponding jumper electrical wires. The connector may be mechanically and electrically coupled to and directly terminate one or more building electrical cables, which may provide power to or from one or more electrical or electronic wiring devices by establishing an electrical pathway from a source of electrical power, through the building electrical cable wires, the connector, the pig-tail jumper electrical wires and an electrical or electronic wiring device.

Abstract: The present invention relates to a device for forming a foam from a cleaning fluid for a wiping system for wiping at least one glazed surface of a vehicle, the device for forming a foam includes at least one cleaning liquid inlet, a chamber intended to receive the cleaning fluid and delimited by a housing, an agitator configured to turn in the chamber about an axis of rotation, a device for driving the agitator, and at least one foam outlet.

Abstract: A refractory lining in a combustion chamber operating in a reducing atmosphere. The lining includes at least one or more Zirconia (Zr)-based refractory lining members comprising one or more Zr-based parts. The Zr-based parts comprise at least 90 wt. %, preferably at least 95 wt. %, of monoclinic ZrO2 and/or partially stabilized ZrO2 and/or fully stabilized ZrO2, wherein the total content of tetragonal and cubic ZrO2 amounts to at least 20 wt. %, preferably more than 35 wt. %, as well as Zr based refractory lining members and methods for manufacturing the Zr based refractory lining members.

Abstract: The present disclosure relates to pharmaceutical compositions comprising (3-((1R,3s,5S)-3-((7-((5-methyl-1H-pyrazol-3-yl)amino)-1,6-naphthyridin-5-yl)amino)-8-azabicyclo[3.2.1]octan-8-yl)propanenitrile), methods of use thereof, and methods of preparation.

Abstract: The invention relates to an electrolysis device and method for producing molecular hydrogen, the device comprising a negative electrode compartment for reducing H2O into H2 and a positive electrode compartment comprising circulating supercapacitive particles in contact with a conductive substrate. Such a device or method advantageously comprises a power supply provided by one or more photovoltaic cells.