Abstract: The invention relates to biomarker Allergin-1 specifically expressed by leukemia stem cells and use thereof. Specifically, the invention relates to methods for identification of LSCs, diagnosis, disease course monitoring and prognosis of leukemia (especially AML), or determination of risk of developing leukemia (especially AML), or determination of the presence of severe leukemia (especially AML) by detecting expression or activity of the biomarker Allergin-1 in a subject or a sample from the subject, in which Allergin-1 is specifically and abnormally highly expressed in LSCs. The invention also provides methods for treating leukemia (especially AML) in a subject by inhibiting/antagonizing expression/activity of Allergin-1.

Abstract: A device for improving quality of aluminum alloy horizontal continuous casting billet by applying ultrasonic treatment is provided, including an ultrasonic generator, an ultrasonic transducer, an amplitude transformer, a holding furnace, an ultrasonic probe and a traction device. The ultrasonic generator is electrically connected with the ultrasonic transducer; the ultrasonic transducer is threadedly connected with the ultrasonic probe through the amplitude transformer, and the ultrasonic probe is placed in the holding furnace; a communication opening is formed at a bottom of the holding furnace, and the traction device is installed at the communication opening; the holding furnace is further poured with metal liquid.

Abstract: An in-situ observation device for gas hydrates includes a reactor, which includes a visual tube, a pulling rod, a temperature-controlled seed crystal rod and a spiral adjuster. An upper end and a lower end of the visual tube are respectively equipped with an upper end cap and a lower end cap. The upper end cap defines an air inlet, and the lower end cap defines a liquid inlet. An upper end of the temperature-controlled seed crystal rod is connected to an adjusting flange. The adjusting flange is connected to the spiral adjuster. A lower end of the temperature-controlled seed crystal rod hermetically passes through the upper end cap and is located in the visual tube. The temperature-controlled seed crystal rod defines a cooling liquid channel, and a cooling liquid inlet and a cooling liquid outlet, a seed crystal rod liquid inlet and a seed crystal rod outlet.

Abstract: The present disclosure provides a reservoir scheduling method considering power generation, an ecological flow, and a surface water temperature. A plurality of optimization objectives of power generation, an ecological flow, and a surface water temperature of a reservoir are determined through analysis, and a multi-objective optimization model is constructed. A non-dominated sorting genetic algorithm III (NSGAII) algorithm is used to obtain an optimal value of a to-be-optimized parameter through solving. Scheduling control is performed on the reservoir based on the optimal value of the to-be-optimized parameter. The present disclosure quantifies a competitive and cooperative relationship among the power generation, the ecological flow, and the surface water temperature of the reservoir by using a multi-objective optimization method, and a reservoir scheduling rule that can balance the power generation, the ecological flow, and the surface water temperature of the reservoir is selected through analysis.

Abstract: An overlapping and progressive forming method for a high-performance multi-element NiAl-based alloy tubular part, including: winding continuously flexible substrates of Ni and Al, and alloying coating continuously or selectively along a width direction or a rolling direction to obtain coated flexible substrates; winding continuously the coated flexible substrates on an outer surface of a core roller according to a sequence of Ni above and Al below to form a Ni/Al laminated structure having a plurality of layers with an outermost layer being a Ni layer, and consolidating with ultrasonic with assistance of a pulse current to combine the continuously wound flexible substrates into a laminated tube blank; and placing the laminated tube blank into a mold, applying a pulse current to both ends of the laminated tube blank for hot fluid high-pressure forming, and synthesizing in-situ to prepare the tubular part with assistance of the pulse current.

Abstract: Provided are a P-type ZrCoSb-based half-Heusler single crystal alloy and a preparation method thereof. The method for preparing the P-type ZrCoSb-based half-Heusler single crystal alloy includes: subjecting alloy raw materials to smelting under a first protective atmosphere to obtain a half-Heusler polycrystalline alloy ingot, the alloy raw materials corresponding to a chemical composition of the P-type ZrCoSb-based half-Heusler single crystal alloy; and subjecting the half-Heusler polycrystalline alloy ingot to vertical Bridgman directional crystallization under a second protective atmosphere to obtain the P-type ZrCoSb-based half-Heusler single crystal alloy. The P-type ZrCoSb-based half-Heusler single crystal alloy has the chemical composition of ZrCoSb1-xSnx, x in the ZrCoSb1-xSnx being in a range of 0.1?x?0.3; and the P-type ZrCoSb-based half-Heusler single crystal alloy has an MgAgAs-type crystal structure.

Abstract: A wireless charging heating system, a wireless charging system, a wireless charging heating method and a wireless charging method are provided.

Abstract: The present application provides a thin-walled shell model updating method and system. The method includes converting an influence of fine feature structures in a space shell structure on stiffness and mass equivalently onto a skin and a stiffener, so as to simulate the influence of the fine feature structures on a bearing capacity of a whole structure.

Abstract: A submicron-sized Pickering miniemulsion system stabilized by carbon quantum dots solid nanoparticles for biphasic catalysis is disclosed, which breaks the existing limits for homogenization of the immiscible biphasic system and overcomes the issues for big size of solid particles-stabilized emulsion droplets. A method for producing the carbon quantum dot-based catalysts and a process of establishing the Pickering miniemulsion system for biphasic reaction with enhanced catalytic efficiency are also disclosed. The carbon quantum dot-stabilized Pickering miniemulsion features a pH-responsive behavior, with a reversible transition between the emulsification and demulsification, triggering the easy & facile product separation and emulsifier/catalyst recycling in one reaction vessel.

Abstract: Solution heat treatment is performed on a blank to dissolve initial coarse secondary phases, to obtain a uniform solid solution microstructure. The blank subjected to the solution heat treatment is transferred into the temperature-controllable forming die to be stamped and quenched. During forming, the temperature and the pressure are further maintained for a period of time. The temperature of the forming die is adjusted to a second-step aging temperature for the second-step aging treatment. In a two-step aging temperature range, stress relaxation occurs while strengthening precipitates are rapidly precipitated, thereby improving strength and dimensional accuracy of the formed part. On the premise of ensuring quality of the formed part, employing stepped aging treatment shortens the aging cycle and reduces energy consumption in the production and manufacturing process.

Abstract: The present disclosure refers to a method and a system of sudden water pollutant source detection by forward-inverse coupling, including: building an one-dimensional forward water quality simulation model of a river way according to acquired mechanical parameters and water quality parameters; according to the one-dimensional forward water quality simulation model of the river way, measuring and calculating each monitoring index by using an inverse optimization source-detection model; by constructing the one-dimensional forward water quality simulation model of the river way, using the inverse optimization source-detection model for measurement and calculation; and performing the Bayesian updating, in order to realize multi-information fusion.

Abstract: The present disclosure belongs to the technical field of walking mechanisms, and provides a smooth obstacle-crossing walking mechanism, which can provide strong smooth obstacle crossing capability, meanwhile, maintains lower friction loss and higher efficiency, and is suitable for most daily use situations. A smooth obstacle-crossing walking mechanism includes a driving wheel and a contact wheel. The driving wheel has a wheel diameter lower than that of the contact wheel. The driving wheel compresses an inner edge of the contact wheel under gravity. The contact wheel is in contact with the ground surface. When the driving wheel rotates actively, it walks along the inner edge of the contact wheel under the frictional force with the contact wheel. The contact wheel rolls forwards under a pressure and the frictional force of the driving wheel, so as to enable the smooth obstacle-crossing walking mechanism to walk.

Abstract: An interface interconnect structure is provided for efficient heat dissipation of a power electronic device. The structure includes a first low temperature solder layer and a second low temperature solder layer, a metal-foam metal composite material is placed between the first low temperature solder layer and the second low temperature solder layer. The metal-foam metal composite material has designability in structure and performance. The thermal conductivity and coefficient of thermal expansion (CTE) of the thermal interface interconnect structure can be configured according to the selected encapsulating materials for a power electronic device, thereby achieving bisynchronous improvement in the heat dissipation efficiency and the CTE matching degree between the encapsulating materials.

Abstract: A main frame structure having box-section bearing beams of a launch vehicle engine includes a body. The body includes upper bearing table tops, lower bearing table tops, a cross gasket, a connecting ring and the box-section bearing beams. The box-section bearing beam includes an upper surface, a lower surface and two side beam walls, and has a cavity structure. Penetrating transverse ribs penetrating the two side beam walls are arranged on the box-section bearing beams, and one ends of the box-section bearing beams are circumferentially distributed at an outer side of the connecting ring. The lower bearing table tops are arranged at the outer side of the connecting ring, the lower bearing table tops are connected to the cross gasket, and the other ends of the upper surfaces and the lower surfaces are connected by means of arc chamfers and are connected to the upper bearing table tops.

Abstract: A metal tin cyclized perylene diimide derivative, having a structure formula of: where R1 and R2 are each independently selected from a hydrogen atom or a group containing or not containing a substituent. The group containing or not containing a substituent is an alkyl having between 1 and 60 carbon atoms, an alkoxy having between 1 and 60 carbon atoms, a cycloalkyl having between 3 and 60 carbon atoms, an aryl having between 5 and 60 atoms, an alkylaryl having between 1 and 60 carbon atoms, an alkylheteroaryl having between 1 and 60 carbon atoms, an alkylheterocyclyl having between 1 and 60 carbon atoms, an alkyleneoxyalkyl having between 1 and 60 carbon atoms, an alkyleneoxyaryl having between 1 and 60 carbon atoms, an alkyleneoxyheteroaryl having between 1 and 60 carbon atoms, or an alkyleneoxyheterocyclyl having between 1 and 60 carbon atoms.

Abstract: A method for reconstructing the crack profiles based on the composite-mode total focusing method (CTFM), including: selecting the parameters for phased array ultrasonic testing; acquiring the A-scan signal matrix; establishing the coordinate system and grid division of the region of interest (ROI); determining the wave modes; solving the positions of the refracted points; reconstructing the image by CTFM; and realizing the quantification, positioning, and orientation of cracks. The A-scan signal matrix including 21 views is acquired. Based on Fermat's principle, the refracted points at the interface between wedge and sample for the 21 views are calculated, to obtain the corresponding amplitude for each view in the ROI. For each reconstruction point, the strongest response is selected from the 21 views. The profiles of the cracks with different orientation angles are reconstructed by CTFM.

Abstract: A method for request scheduling in an unmanned aerial vehicle-assisted mobile edge computing network: determining multiple feasible UAV deployment points based on obstruction information in a target area; randomly selecting U feasible UAV deployment points from the multiple feasible UAV deployment points as UAV deployment points; dividing each UAV into multiple virtual UAVs; allocating user requests in a central queue of a UAV-assisted MEC to the virtual UAVs; using a round-robin policy to schedule the user requests allocated to each virtual UAV; after a specified time period t, if a network pressure mitigation condition isn't met, inputting historical user request data of each feasible UAV deployment point into a trained MT-LSTM neural network model, obtaining a to-be-processed data volume of each feasible UAV deployment point in a next specified time period t; re-determining UAV deployment points; redeploying UAVs carrying small cell base stations based on the new UAV deployment points.

Abstract: A CaTiO3-based oxide thermoelectric material and a preparation method thereof are disclosed. The CaTiO3-based oxide thermoelectric material has a chemical formula of Ca1-xLaxTiO3, where 0<x?0.4. The present disclosure makes it possible to prepare a CaTiO3-based thermoelectric material with properties comparable to n-type ZnO, CaTiO3, SrTiO3 and other oxide thermoelectric materials. Among them, the La15 sample has a power factor reaching up to 8.2 ?Wcm?1K?2 (at about 1000 K), and a power factor reaching up to 9.2 ?Wcm?1K?2 at room temperature (about 300 K); and a conductivity reaching up to 2015 Scm?1 (at 300 K). The CaTiO3-based oxide thermoelectric material exhibits the best thermoelectric performance among calcium titanate ceramics. The method for preparing the CaTiO3-based oxide thermoelectric material of the present disclosure is simple in process, convenient in operation, low in cost, and makes it possible to prepare a CaTiO3-based ceramic sheet with high thermoelectric performance.

Abstract: The present disclosure relates to the technical field of fiber-optic gas sensing and laser photoacoustic spectroscopy, and reliability of a gas detection system is improved by actively selecting a working frequency of low noise interference combined with an optical fiber photoacoustic sensing probe capable of isolating high-frequency noise. A gas enters a photoacoustic microcavity through gaps on a sound-sensitive diaphragm after diffusing into a miniature air chamber through a plurality of micropores. Photoacoustic excitation light is incident into the photoacoustic microcavity through a fiber-optic collimator and then excited to generate a photoacoustic pressure wave to cause the sound-sensitive diaphragm to vibrate periodically. An end face of a single-mode optical fiber and the sound-sensitive diaphragm constitutes a fiber-optic Fabry-Perot interferometer. The interferometer measures a deflection of the diaphragm and inverts a concentration of the to-be-measured gas.

Abstract: The present invention provides a method for forming an aluminum alloy thin-walled curved part by ultra-low temperature gradient drawing. This method includes: placing the aluminum alloy sheet on a die, and closing a blank holder to hold the aluminum alloy sheet in a flange zone; filling a cavity of a die with an ultra-low temperature medium to cool a die cavity zone of the aluminum alloy sheet to a set low temperature, and forming an ultra-low temperature gradient in which the temperature of the die cavity zone is lower than the temperature in the flange zone; applying a set blank holder force to the blank holder, and controlling a punch to move downwards to form a deep-cavity thin-walled curved part; and controlling the punch to move upwards, opening the blank holder, and taking out the formed deep-cavity thin-walled curved part.