Abstract: An assembly for driving linear movement and roll movement of an elongate surgical tool, comprising: an elongate shaft comprising a central lumen extending along the shaft long axis; the elongate shaft comprising a plurality of apertures extending across walls of the elongate shaft and into the central lumen; a set of wheels positioned opposing each other and aligned on two sides of the central lumen, the set of wheels at least partially extending through the apertures beyond the walls of the elongate shaft and into the central lumen to contact an elongate surgical tool received therein; the set of wheels being coupled to the elongate shaft and configured to rotate with the elongate shaft as a single unit when the elongate shaft is rotated about the shaft long axis.

Abstract: There is provided an ultrasound device comprising: ultrasound transducer(s), memory storing code, hardware processor(s) coupled to the ultrasound transducer(s) and the memory for executing stored code comprising: activating the transducer(s) for simultaneously transmitting at least one line with a predefined focus width, and receiving an indication of a plurality of narrow-focused received lines, inputting the indication of the narrow-focused received lines into a convolutional neural network (CNN) trained on pairs of ultrasound imaging data capturing rapid motion of the certain tissue of sample patient(s), including a single-line ultrasound imaging data captured based on a single line in response to a transmitted single narrow-focused pulse, and a multiple-line ultrasound imaging data captured based on receiving narrow-focused lines in response to simultaneously transmitted at least one line, outputting adjusted narrow-focused received lines, and computing an adjusted ultrasound image according to the adjust

Abstract: A method of processing a query to a graph database using processors. The method comprises providing threads to be executed on processors, each the thread is associated with one of a plurality of unique thread identifiers, providing a graph database having a plurality of graph database nodes and a plurality of graph database edges, each the graph database edge represents a relationship between two of the plurality of graph database nodes, receiving a query tree that defines a tree comprising plurality of query nodes connected by a plurality of query tree edges, and searching at least part of the graph database for a match with the query tree, wherein the searching is executed by the processors, and wherein each processor searches one of a plurality of sub-graphs of the graph database, each the sub-graph is defined by one of the plurality of thread identifiers.

Abstract: The present invention provides a self-healing platform unit for pressure and analyte sensing, and a method for fabrication thereof, the platform unit comprising a self-healing substrate comprising a dynamically crosslinked polymer comprising polymeric chains and crosslinking bridges; at least one self-healing electrode comprising a non-crosslinked polymer and metal microparticles dispersed therein, wherein the at least one self-healing electrode is deposited on the substrate; and at least one sensor comprising metal nanoparticles capped with an organic coating, wherein the at least one sensor is deposited on the substrate and is in electric contact with the at least one self-healing electrode.

Abstract: A computing device, comprising at least one peripheral computing component, electrically connected to each of a plurality of hardware processors; wherein at least one of the plurality of hardware processors is adapted to executing a code for: configuring the at least one peripheral computing component to access at least one first memory location in a first memory component electrically coupled with a first hardware processor of the plurality of hardware processors via a first electrical connection between the peripheral computing component and the first hardware processor; and configuring the at least one peripheral computing component to access at least one second memory location in a second memory component electrically coupled with a second hardware processor of the plurality of hardware processors via a second electrical connection between the peripheral computing component and the second hardware processor; and wherein the first hardware processor is not the second hardware processor.

Abstract: A compact robotic device for driving movement of two or more elongate surgical tools configured for a telescopic arrangement when said two or more elongate surgical tools are at least partially received within said device, the device comprising: a housing comprising walls which define an inner volume including at least two inner pathways for accommodating the two or more elongate surgical tools; the housing encasing: a plurality of motors, and two or more tool actuation assemblies configured at a position of each of the two or more inner pathways; the actuation assemblies driven by the plurality of motors and configured to operably contact an elongate surgical tool at least partially received in the inner pathway to at least one of advance, retract and/or roll said elongate surgical tool.

Abstract: Methods and compositions for diagnosing and vaccinating against Ehrlichia chaffeensis are provided.

Abstract: A system for training a quantized neural network dataset, comprising at least one hardware processor adapted to: receive input data comprising a plurality of training input value sets and a plurality of target value sets; in each of a plurality of training iterations: for each layer, comprising a plurality of weight values, of one or more of a plurality of layers of a neural network: compute a set of transformed values by applying to a plurality of layer values one or more emulated non-uniformly quantized transformations by adding to each of the plurality of layer values one or more uniformly distributed random noise values; and compute a plurality of output values; compute a plurality of training output values; and update one or more of the plurality of weight values to decrease a value of a loss function; and output the updated plurality of weight values of the plurality of layers.

Abstract: The invention provides isolated peptides from the protein EMMPRIN (CD147/Basigin) and antibodies directed against antigenic determinants within said peptides. Pharmaceutical compositions comprising said peptides and antibodies are also disclosed as well as methods of their production and use in vaccination, immunotherapy and diagnosis of proliferative, hyperpermeability, inflammatory, and angiogenesis-related diseases and disorders.

Abstract: There is provided a gas sensing device for sensing a certain gas that is associated with a certain spectral band, the gas sensing device may include a passive gas sensor that is configured to generate passive gas sensor detection signals that are responsive to the certain spectral band; a passive dummy sensor that is configured to generate passive dummy sensor detection signals that are indifferent to the certain spectral hand; and at least one circuit that is configured to detect a presence or absence of the certain gas within a certain volume that is located within the fields of view of the passive gas sensor and the passive dummy sensor based on a comparison between the passive gas sensor detection signals and the passive dummy sensor detection signals.

Abstract: A reliability based keyframe switching system adaptable to iterative closest point (ICP) includes a camera that captures frames; a matching device that determines corresponding pairing between the frames for an ICP operation to form a set of plural point-pairs; a transformation device that performs transformation estimation to estimate transformation that minimizes distances of the point-pairs, and determines whether the estimated transformation converges; and a reliability device that determines whether the ICP operation is reliable, and replaces a current keyframe with a new keyframe if the ICP operation is determined to be unreliable.

Abstract: A new class of pseudo-trisaccharide aminoglycosides having an alkyl group at the 5? position, exhibiting efficient stop codon mutation readthrough activity, low cytotoxicity and high selectivity towards eukaryotic translation systems are provided. Also provided are pharmaceutical compositions containing the same, and uses thereof in the treatment of genetic disorders, as well as processes of preparing these aminoglycosides. The disclosed aminoglycosides can be represented by the general formula I: or a pharmaceutically acceptable salt thereof, wherein R1 is selected from the group consisting of alkyl, cycloalkyl and aryl; and all other variables and features are as described in the specification.

Abstract: Compositions comprising liposomes composed of whole cell membrane fraction are provided. The liposomes may be attached to, or encapsulate a pharmaceutical agent. Also provided are methods of generating and using these liposomes.

Abstract: In some aspects, mutant or variant Fc domains are provided that exhibit increased binding to FcRn and increased half-life after administration in vivo. The Fc domain may be comprised in a glycosylated or aglycosylated antibody. Methods for using the mutant or variant Fc domains or polypeptides comprising the mutant or variant Fc domains are also provided.

Abstract: A method comprising acquiring a first image of a scene inside a medium, under illumination from a first location or orientation. The method comprises an action of acquiring a second image of the scene inside the medium, under illumination from a second, different location or orientation. The method comprises an action of computing attenuation coefficients, one per color channel, based on backscatter in the first and second images.

Abstract: There is provided a method of representing a three dimensional (3D) object using univariate curves, comprising: receiving an initial definition of a 3D object representation, calculate a covering set of univariate curves, the covering set comprising at least one non-planar univariate curve, wherein the covering set of univariate curves represent the volume of the 3D object within a tolerance requirement, and generating a representation of the 3D object based on the set of univariate curves, wherein the set of univariate curves represent the volume of the 3D object.

Abstract: A method for dielectrophoresis includes applying an electric field across a micro-fluidic chamber with an alternating current (AC), trapping the target particles on the at least one carrier particle, transporting the target particles from a first location in the chamber to a second location in the chamber distanced from the first location with the at least one carrier particle and dynamically controlling the trapping and the transporting based on remotely applying forces on the at least one carrier particle. The trapping is based on localized gradients of the electric field induced by the carrier particle. The applied electric field is uniform absent a carrier particle present in the micro-fluidic chamber. The micro-fluidic chamber contains an electrolyte-solution with suspended target particles and at least one carrier particle freely floating on or in the electrolyte-solution.

Abstract: A pharmaceutical composition and a method of treating, reducing or preventing vascular, cardiovascular arterial or valve calcification in a subject in need comprising administering to the subject an effective amount of an agent that prevents or reduces the expression of HDAC4, an agent that modulates the location of HDAC4, an agent that binds to HDAC4 or an inhibitor of HDAC4 or any combination thereof is provided. In some embodiments, there is provided a pharmaceutical composition comprising: an agent that prevents or reduces the expression of HDAC4, an agent that modulates the location of HDAC4, an agent that binds to HDAC4 or an inhibitor of HDAC4 or any combination thereof; an agent that prevents or reduces the expression of SIK or is an inhibitor of SIK; and/or an agent that prevents or reduces the expression of ENIGMA (Pdlim7) or is an inhibitor of ENIGMA.

Abstract: A matrix data processing method performed by a computing device which performs a matrix multiplication operation includes, with respect to each of one or more elements included in a matrix, when a value of each element satisfies a designated condition, determining the element to be a don't-care element and determining an output value of the don't-care element, generating a bitstream based on the output value of the don't-care element and index values of valid elements included in the matrix, and equally dividing the bitstream into pieces of a designated number, and generating a Huffman code corresponding to each of a plurality of lower bitstreams that are generated as a result of the equal division.

Abstract: The present disclosure provides a quantum dot thin film that is formed by cross-linking ligands of quantum dots with a photo cross-linker containing two or more azide groups. According to still another aspect of the present disclosure, a method for forming a quantum dot pattern includes: forming a quantum dot layer on a substrate by coating the substrate with a solution including quantum dots and a photo cross-linker containing two or more azide groups; placing a mask having a pattern on the quantum dot layer and performing UV exposure on the quantum dot layer; and forming a quantum dot pattern by removing a non-exposed region of the quantum dot layer.