Abstract: A three-dimensional fibrin engineered tissue construct is provided selected from: (i) a fibrin gel matrix comprising a combination of tissue-specific cells and at least one type of vascular cells; and (ii) a hybrid scaffold of fibrin gel and a polymeric synthetic scaffold comprising at least one type of vascular cells or a combination of tissue-specific cells and at least one type of vascular cells.
Type:
Grant
Filed:
February 13, 2012
Date of Patent:
June 29, 2021
Assignee:
TECHNION RESEARCH DEVELOPMENT FOUNDATION LTD.
Abstract: A single-ended successive approximation register (SAR) analog-to-digital converter (ADC) includes a first digital-to-analog converter (DAC) having a first capacitor associated with a most significant bit (MSB) of the output code, and a second capacitor associated with other bit or bits of the output code; and a second DAC having a first capacitor associated with a MSB of the output code, and a second capacitor associated with other bit or bits of the output code. A bottom plate of the first capacitor of the second DAC is connected to a negative reference voltage in all phases.
Type:
Grant
Filed:
August 10, 2020
Date of Patent:
June 29, 2021
Assignees:
NCKU Research and Development Foundation, Himax Technologies Limited
Abstract: A chip includes a substrate; macros placed on the substrate, which has a placement region being divided into sub-regions according to locations of the macros; and one or more vertical power stripes (VPSs) disposed in each sub-region. At least one VPS is not aligned with the VPSs of an adjacent higher or lower sub-region.
Type:
Grant
Filed:
November 6, 2019
Date of Patent:
June 29, 2021
Assignees:
NCKU Research and Development Foundation, Himax Technologies Limited
Abstract: Provided herein are chimeric polypeptides that may be used, e.g., for the diagnosis of or vaccination against Ehrlichia chaffeensis and/or Ehrlichia canis.
Abstract: A method of expanding and maintaining human embryonic stem cells (ESCs) in an undifferentiated state by culturing the ESCs in a suspension culture under culturing conditions devoid of substrate adherence is provided. Also provided are a method of deriving ESC lines in the suspension culture and methods of generating lineage-specific cells from ESCs which were expanded in the suspension culture of the present invention.
Type:
Application
Filed:
February 18, 2021
Publication date:
June 24, 2021
Applicant:
Technion Research & Development Foundation Limited
Abstract: Provided is a superabsorbent structure based on a covalently crosslinked copolymer having a microstructure of a HIPE, and characterized by hydrophobic and hydrophilic segments of at least five residues; the unique chemical and structural properties of the copolymer afford a polymeric superabsorbent structure that is capable of swelling in polar as well as apolar media. Also provided are processes of manufacturing the superabsorbent structure, and uses thereof.
Type:
Application
Filed:
April 25, 2019
Publication date:
June 24, 2021
Applicant:
Technion Research & Development Foundation Limited
Abstract: A method tor the preparation of a highly polarized nuclear spins containing sample of an organic or inorganic material, containing H or OH groups or adsorbed water molecules. Such highly polarized nuclear spins containing samples can be subjected to nuclear magnetic resonance (NMR) measurement and/or can be thawed and immediately administered to an individual undergoing a magnetic resonance imaging (MRI) scan. The method is based on generating unstable radicals on the surface of the sample in the presence of ionized environment followed by cooling the sample to cryogenic temperatures. A device for carrying out a particular step of said method is also discloses.
Type:
Grant
Filed:
June 3, 2020
Date of Patent:
June 22, 2021
Assignees:
Technion Research & Development Foundation Limited, Yeda Research and Development Co. Ltd.
Abstract: A sensing device that may include a substrate; a single-ended SPAD; first electrical components; second electrical components; and capacitors. The SPAD, the first electrical components and the second electrical components are formed on the substrate. The SPAD and the first electrical components belong to a high voltage domain of the sensing device. The high voltage domain is configured to receive a high supply voltage that exceeds a breakdown voltage of the SPAD. The second electrical components belong to a low voltage domain of the sensing device. The capacitors are coupled between the low voltage domain and the high voltage domain. The first electrical components and the second electrical components belong to an electrical circuit that is configured to perform quenching of the SPAD.
Type:
Grant
Filed:
February 11, 2020
Date of Patent:
June 15, 2021
Assignee:
TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITED
Abstract: A system and method to measure blood oxygenation levels and total hemoglobin on individually selected blood vessels, to provide a representation of the subject condition and of tissue perfusion that may be used for diagnosing specific tissue conditions. Reflection spectra from individual blood vessels or a collection of vessels are measured by using wide-field imaging for selecting target vessels and a narrow-field confocal detection system to enable measuring local blood oxygenation and hemoglobin. Optical fibers may be used to illuminate the target vessel and to detect light diffusively reflected therefrom. The reflection spectra may be analyzed in a spectrometer to extract the ratio of the deoxy- to oxyhemoglobin and to determine their absolute concentration for computing total hemoglobin levels. An alternative implementation uses image processing on camera images of a blood vessel, generated at an isosbestic wavelength of the deoxy- and oxyhemoglobin, and optionally also at neighboring wavelengths.
Type:
Grant
Filed:
November 30, 2016
Date of Patent:
June 15, 2021
Assignee:
TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITED
Abstract: Provided is a ternary logic synthesis method at least temporarily performed by a computer, the ternary logic synthesis method including generating a switching table with respect to pull-up and pull-down circuits using a truth table corresponding to a ternary function, converting the switching table into a sum of products (SOP) using a Quine-McCluskey algorithm, minimizing the SOP, and mapping a transistor corresponding to the SOP.
Type:
Grant
Filed:
December 13, 2019
Date of Patent:
June 15, 2021
Assignee:
POSTECH RESEARCH AND BUSINESS DEVELOPMENT FOUNDATION
Inventors:
Seokhyeong Kang, Sunmean Kim, Sung-Yun Lee
Abstract: An atmospheric moisture harvesting system, in which water vapor is separated from the air using a liquid desiccant subsystem. The moisture charged liquid desiccant enters a desorber and condensation system, where the moisture is extracted. Cooling and condensation are performed on the extracted water vapor only, thereby saving the energy for cooling air containing the water vapor, as is done in direct cooling systems. The system thus operates as a single stage vapor separation system since the vapor concentration remains in the liquid desiccant which is circulated to the separation and condensation subsystems without air laden with the moisture. Low grade or solar heat can be used as the energy source for the vapor desorption. A heat exchanger utilizes unwanted heat from regenerated desiccant to heat up charged desiccant entering the regenerating stage. The system has substantial energy savings over prior art systems using direct cooling of air.
Type:
Grant
Filed:
June 26, 2017
Date of Patent:
June 1, 2021
Assignee:
TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LIMITED
Abstract: A composite comprised of: (i) at least one inverse freezing material, and (ii) an additive in the form of at least one solid particle. Articles made of the composites, and uses of the composites or the articles incorporating same, particularly for reducing incoming shockwaves, are also disclosed.
Type:
Grant
Filed:
June 4, 2018
Date of Patent:
June 1, 2021
Assignee:
TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITED
Inventors:
Galit Parvari, Daniel Rittel, Yonatan Rotbaum, Yoav Eichen
Abstract: A method for detecting a pattern of events, comprising: receiving a template defining the pattern of events to detect; producing a join query for a relational database from the template; selecting a cost function for the join query, wherein a computation cost of the join query is equivalent to a computation cost of matching between a plurality of events from a plurality of streams of events and the template; identifying a preferred plan for executing the join query according to a minimal value of the cost function; producing an ordered set of a plurality of patterns, according to the preferred plan, by converting a plurality of database operations of the preferred plan into the ordered set of the plurality of patterns; and using the ordered set as an input for detecting a plurality of matches between the plurality of patterns and the plurality of events.
Type:
Grant
Filed:
July 25, 2018
Date of Patent:
May 25, 2021
Assignee:
Technion Research & Development Foundation Limited
Abstract: The invention provides compositions, kits and methods for depositing a composition comprising a plurality of magnetic particles, to a target site of a subject by delivering the composition via controlled inhalation to a region of the subject's respiratory tract and applying a magnetic field to a target site within the region of the subject's respiratory tract to capture the particles in said target site.
Type:
Grant
Filed:
April 25, 2017
Date of Patent:
May 25, 2021
Assignee:
TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITED
Abstract: A system for generating cold plasma is presented, suitable for use in in-vivo treatment of biological tissue. The system comprising: a control unit connectable to an elongated member at a first proximal end of the elongated member. The elongated member comprises a plasma generating unit at a second distal end thereof and gas and electricity transmission channels extending from said first proximal end towards said plasma generating unit. The control unit comprises a gas supply unit configured to provide predetermined flow rate of selected gas composition through said gas transmission channel and a power supply unit configured to generate selected sequence of high-frequency electrical pulses, typically in mega Hertz range, directed through said electricity transmission channel, thereby providing power and gas of said selected composition to the plasma generating unit for generating cold plasma.
Type:
Grant
Filed:
November 19, 2015
Date of Patent:
May 18, 2021
Assignees:
Technion Research & Development Foundation Limited, Rambam Med-Tech Ltd.
Abstract: A digital to analog converter is constructed using a neural network layer. The converter has inputs for receiving parallel bits of a digital input signal and an output for outputting an analog signal which is based on the digital input. Connecting the input and the output is a neural network layer which is configured to convert the parallel bits into an output analog signal that is representative of the digital input signal. The neural network may be hardwired and the synapses may rely on memristors as programmable elements.
Type:
Application
Filed:
July 11, 2018
Publication date:
May 13, 2021
Applicant:
Technion Research & Development Foundation Limited
Abstract: An image processing apparatus is provided. The image processing apparatus includes a memory configured to store at least one instruction; and a processor configured to read the at least one instruction and configured to, according to the at least one instruction: apply a learning network model to an input image frame and acquire information on an area of interest; and acquire an output image frame by retargeting the input image frame based on the acquired information on the area of interest. The learning network model is a model that is trained to acquire the information on the area of interest in the input image frame.
Type:
Grant
Filed:
May 23, 2019
Date of Patent:
May 11, 2021
Assignees:
SAMSUNG ELECTRONICS CO., LTD., Sogang University Research & Business Development Foundation
Inventors:
Hyungjun Lim, Suk-Ju Kang, Seung Joon Lee, Youngsu Moon, Siyeong Lee, Sung In Cho
Abstract: A hybrid computer that comprises a sequential processor, a single instruction massively parallel (SIMD) processor, and shared memory module that is shared between the sequential processor and the SIMD processor.
Type:
Grant
Filed:
January 7, 2016
Date of Patent:
May 4, 2021
Assignee:
TECHNION RESEARCH AND DEVELOPMENT FOUNDATION LTD.
Inventors:
Amir Morad, Leonid Yavits, Shahar Kvatinsky, Ran Ginosar
Abstract: A method of manipulating a living cell is disclosed. The method comprises, directing a pulsed optical field to at least one conductive nanoparticle present in the vicinity of the cell, so as to generate cavitations at or near the conductive nanoparticle at sufficient amount to effect at least one cell modification selected from the group consisting of cell-damage and cell-fusion.
Type:
Grant
Filed:
January 19, 2012
Date of Patent:
May 4, 2021
Assignee:
Technion Research & Development Foundation Limited