Patents Assigned to DexCom, Inc.
  • Analyte sensors and methods of manufacturing same
    Patent number: 8828201
    Abstract: Analyte sensors and methods of manufacturing same are provided, including analyte sensors comprising multi-axis flexibility. For example, a multi-electrode sensor system 800 comprising two working electrodes and at least one reference/counter electrode is provided. The sensor system 800 comprises first and second elongated bodies E1, E2, each formed of a conductive core or of a core with a conductive layer deposited thereon, insulating layer 810 that separates the conductive layer 820 from the elongated body, a membrane layer deposited on top of the elongated bodies E1, E2, and working electrodes 802?, 802? formed by removing portions of the conductive layer 820 and the insulating layer 810, thereby exposing electroactive surface of the elongated bodies E1, E2.
    Type: Grant
    Filed: July 1, 2010
    Date of Patent: September 9, 2014
    Assignee: DexCom, Inc.
    Inventors: Peter C. Simpson, Robert Boock, Paul V. Neale, Sebastian Bohm, Matthew Wightlin, Jack Pryor, Jason Mitchell, Jeff Jackson, Kaushik Patel, Antonio C. Llevares
  • Transcutaneous analyte sensor
    Patent number: 8825127
    Abstract: The present invention relates generally to systems and methods for measuring an analyte in a host. More particularly, the present invention relates to systems and methods for transcutaneous measurement of glucose in a host.
    Type: Grant
    Filed: May 14, 2010
    Date of Patent: September 2, 2014
    Assignee: DexCom, Inc.
    Inventors: Apurv Ullas Kamath, James Brauker, J. Michael Dobbles
  • Systems and methods for replacing signal artifacts in a glucose sensor data stream
    Patent number: 8821400
    Abstract: Systems and methods for minimizing or eliminating transient non-glucose related signal noise due to non-glucose rate limiting phenomenon such as ischemia, pH changes, temperatures changes, and the like. The system monitors a data stream from a glucose sensor and detects signal artifacts that have higher amplitude than electronic or diffusion-related system noise. The system replaces some or the entire data stream continually or intermittently including signal estimation methods that particularly address transient signal artifacts. The system is also capable of detecting the severity of the signal artifacts and selectively applying one or more signal estimation algorithm factors responsive to the severity of the signal artifacts, which includes selectively applying distinct sets of parameters to a signal estimation algorithm or selectively applying distinct signal estimation algorithms.
    Type: Grant
    Filed: February 9, 2011
    Date of Patent: September 2, 2014
    Assignee: DexCom, Inc.
    Inventors: Paul V. Goode, Jr., James H. Brauker, Apurv U. Kamath, James Patrick Thrower, Victoria Carr-Brendel
  • Systems and methods for replacing signal artifacts in a glucose sensor data stream
    Patent number: 8812073
    Abstract: Systems and methods for minimizing or eliminating transient non-glucose related signal noise due to non-glucose rate limiting phenomenon such as ischemia, pH changes, temperatures changes, and the like. The system monitors a data stream from a glucose sensor and detects signal artifacts that have higher amplitude than electronic or diffusion-related system noise. The system replaces some or the entire data stream continually or intermittently including signal estimation methods that particularly address transient signal artifacts. The system is also capable of detecting the severity of the signal artifacts and selectively applying one or more signal estimation algorithm factors responsive to the severity of the signal artifacts, which includes selectively applying distinct sets of parameters to a signal estimation algorithm or selectively applying distinct signal estimation algorithms.
    Type: Grant
    Filed: June 1, 2010
    Date of Patent: August 19, 2014
    Assignee: DexCom, Inc.
    Inventors: Paul V. Goode, Jr., James H. Brauker, Apurv U. Kamath, James Patrick Thrower, Victoria Carr-Brendel
  • System and methods for processing analyte sensor data
    Patent number: 8808182
    Abstract: Systems and methods for processing sensor analyte data, including initiating calibration, updating calibration, evaluating clinical acceptability of reference and sensor analyte data, and evaluating the quality of sensor calibration. During initial calibration, the analyte sensor data is evaluated over a period of time to determine stability of the sensor. The sensor may be calibrated using a calibration set of one or more matched sensor and reference analyte data pairs. The calibration may be updated after evaluating the calibration set for best calibration based on inclusion criteria with newly received reference analyte data. Fail-safe mechanisms are provided based on clinical acceptability of reference and analyte data and quality of sensor calibration. Algorithms provide for optimized prospective and retrospective analysis of estimated blood analyte data from an analyte sensor.
    Type: Grant
    Filed: April 27, 2012
    Date of Patent: August 19, 2014
    Assignee: DexCom, Inc.
    Inventors: Paul V. Goode, James H. Brauker, Apurv Ullas Kamath, James Patrick Thrower
  • Integrated medicament delivery device for use with continuous analyte sensor
    Patent number: 8808228
    Abstract: An integrated system for the monitoring and treating diabetes is provided, including an integrated receiver/hand-held medicament injection pen, including electronics, for use with a continuous glucose sensor. In some embodiments, the receiver is configured to receive continuous glucose sensor data, to calculate a medicament therapy (e.g., via the integrated system electronics) and to automatically set a bolus dose of the integrated hand-held medicament injection pen, whereby the user can manually inject the bolus dose of medicament into the host. In some embodiments, the integrated receiver and hand-held medicament injection pen are integrally formed, while in other embodiments they are detachably connected and communicated via mutually engaging electrical contacts and/or via wireless communication.
    Type: Grant
    Filed: June 5, 2008
    Date of Patent: August 19, 2014
    Assignee: DexCom, Inc.
    Inventors: Mark C. Brister, Nelson Quintana, Antonio C. Llevares, John Michael Dobbles, Richard C. Yang, Michael Robert Mensinger
  • Transcutaneous medical device with variable stiffness
    Patent number: 8812072
    Abstract: The present invention relates generally to variable stiffness transcutaneous medical devices including a distal portion designed to be more flexible than a proximal portion. The variable stiffness can be provided by a variable pitch in one or more wires of the device, a variable cross-section in one or more wires of the device, and/or a variable hardening and/or softening in one or more wires of the device.
    Type: Grant
    Filed: April 17, 2008
    Date of Patent: August 19, 2014
    Assignee: DexCom, Inc.
    Inventors: Mark Brister, James H. Brauker
  • System and methods for processing analyte sensor data
    Patent number: 8801612
    Abstract: Systems and methods for processing sensor analyte data, including initiating calibration, updating calibration, evaluating clinical acceptability of reference and sensor analyte data, and evaluating the quality of sensor calibration. During initial calibration, the analyte sensor data is evaluated over a period of time to determine stability of the sensor. The sensor may be calibrated using a calibration set of one or more matched sensor and reference analyte data pairs. The calibration may be updated after evaluating the calibration set for best calibration based on inclusion criteria with newly received reference analyte data. Fail-safe mechanisms are provided based on clinical acceptability of reference and analyte data and quality of sensor calibration. Algorithms provide for optimized prospective and retrospective analysis of estimated blood analyte data from an analyte sensor.
    Type: Grant
    Filed: April 27, 2012
    Date of Patent: August 12, 2014
    Assignee: DexCom, Inc.
    Inventors: Paul V. Goode, James H. Brauker, Apurv Ullas Kamath, James Patrick Thrower
  • Transcutaneous analyte sensor
    Patent number: 8801611
    Abstract: The present invention relates generally to systems and methods for measuring an analyte in a host. More particularly, the present invention relates to systems and methods for transcutaneous measurement of glucose in a host.
    Type: Grant
    Filed: March 22, 2010
    Date of Patent: August 12, 2014
    Assignee: DexCom, Inc.
    Inventors: Mark Brister, Paul V. Neale, Sean Saint, James Patrick Thrower, Thomas F. McGee, Daniel Shawn Codd, David Michael Petersen, Daniel S. Kline
  • Signal processing for continuous analyte sensor
    Patent number: 8801610
    Abstract: Systems and methods for dynamically and intelligently estimating analyte data from a continuous analyte sensor, including receiving a data stream, selecting one of a plurality of algorithms, and employing the selected algorithm to estimate analyte values. Additional data processing includes evaluating the selected estimative algorithms, analyzing a variation of the estimated analyte values based on statistical, clinical, or physiological parameters, comparing the estimated analyte values with corresponding measure analyte values, and providing output to a user. Estimation can be used to compensate for time lag, match sensor data with corresponding reference data, warn of upcoming clinical risk, replace erroneous sensor data signals, and provide more timely analyte information encourage proactive behavior and preempt clinical risk.
    Type: Grant
    Filed: July 24, 2009
    Date of Patent: August 12, 2014
    Assignee: DexCom, Inc.
    Inventors: James H. Brauker, Victoria Carr-Brendel, Paul V. Goode, Apurv U. Kamath, James P. Thrower, Ben Xavier
  • Systems and methods for replacing signal artifacts in a glucose sensor data stream
    Patent number: 8795177
    Abstract: Systems and methods for minimizing or eliminating transient non-glucose related signal noise due to non-glucose rate limiting phenomenon such as ischemia, pH changes, temperatures changes, and the like. The system monitors a data stream from a glucose sensor and detects signal artifacts that have higher amplitude than electronic or diffusion-related system noise. The system replaces some or the entire data stream continually or intermittently including signal estimation methods that particularly address transient signal artifacts. The system is also capable of detecting the severity of the signal artifacts and selectively applying one or more signal estimation algorithm factors responsive to the severity of the signal artifacts, which includes selectively applying distinct sets of parameters to a signal estimation algorithm or selectively applying distinct signal estimation algorithms.
    Type: Grant
    Filed: January 14, 2009
    Date of Patent: August 5, 2014
    Assignee: DexCom, Inc.
    Inventors: Paul V. Goode, Jr., James H. Brauker, Apurv U. Kamath, James Patrick Thrower, Victoria Carr-Brendel
  • ANALYTE SENSOR
    Publication number: 20140213869
    Abstract: Systems and methods of use for continuous analyte measurement of a host's vascular system are provided. In some embodiments, a continuous glucose measurement system includes a vascular access device, a sensor and sensor electronics, the system being configured for insertion into a host's peripheral vein or artery.
    Type: Application
    Filed: April 18, 2014
    Publication date: July 31, 2014
    Applicant: DexCom, Inc.
    Inventors: Mark Brister, Sean Saint, Vance Swanson, Nelson Quintana
  • Systems and methods for replacing signal artifacts in a glucose sensor data stream
    Patent number: 8790260
    Abstract: Systems and methods for minimizing or eliminating transient non-glucose related signal noise due to non-glucose rate limiting phenomenon such as ischemia, pH changes, temperatures changes, and the like. The system monitors a data stream from a glucose sensor and detects signal artifacts that have higher amplitude than electronic or diffusion-related system noise. The system replaces some or the entire data stream continually or intermittently including signal estimation methods that particularly address transient signal artifacts. The system is also capable of detecting the severity of the signal artifacts and selectively applying one or more signal estimation algorithm factors responsive to the severity of the signal artifacts, which includes selectively applying distinct sets of parameters to a signal estimation algorithm or selectively applying distinct signal estimation algorithms.
    Type: Grant
    Filed: October 14, 2009
    Date of Patent: July 29, 2014
    Assignee: DexCom, Inc.
    Inventors: Paul V. Goode, Jr., James H. Brauker, Apurv U. Kamath, James Patrick Thrower, Victoria Carr-Brendel
  • Transcutaneous analyte sensor
    Patent number: 8792953
    Abstract: The present invention relates generally to systems and methods for measuring an analyte in a host. More particularly, the present invention relates to systems and methods for transcutaneous measurement of glucose in a host.
    Type: Grant
    Filed: March 19, 2010
    Date of Patent: July 29, 2014
    Assignee: DexCom, Inc.
    Inventors: Mark Brister, Paul V. Neale, James Brauker, James Patrick Thrower
  • Transcutaneous analyte sensor
    Patent number: 8792954
    Abstract: The present invention relates generally to systems and methods for measuring an analyte in a host. More particularly, the present invention relates to systems and methods for transcutaneous measurement of glucose in a host.
    Type: Grant
    Filed: March 19, 2010
    Date of Patent: July 29, 2014
    Assignee: DexCom, Inc.
    Inventors: Mark Brister, Paul V. Neale, James Brauker
  • Transcutaneous analyte sensor
    Patent number: 8792955
    Abstract: The present invention relates generally to systems and methods for measuring an analyte in a host. More particularly, the present invention relates to systems and methods for transcutaneous measurement of glucose in a host.
    Type: Grant
    Filed: June 9, 2011
    Date of Patent: July 29, 2014
    Assignee: DexCom, Inc.
    Inventors: Mark Brister, Paul V. Neale, Peter C. Simpson, James H. Brauker, James Patrick Thrower, Mark Shults, Rathburn K. Rhodes, Paul V. Goode, Jr., Arnold L. Holmquist
  • System and methods for processing analyte sensor data
    Patent number: 8788008
    Abstract: Systems and methods for processing sensor analyte data, including initiating calibration, updating calibration, evaluating clinical acceptability of reference and sensor analyte data, and evaluating the quality of sensor calibration. During initial calibration, the analyte sensor data is evaluated over a period of time to determine stability of the sensor. The sensor may be calibrated using a calibration set of one or more matched sensor and reference analyte data pairs. The calibration may be updated after evaluating the calibration set for best calibration based on inclusion criteria with newly received reference analyte data. Fail-safe mechanisms are provided based on clinical acceptability of reference and analyte data and quality of sensor calibration. Algorithms provide for optimized prospective and retrospective analysis of estimated blood analyte data from an analyte sensor.
    Type: Grant
    Filed: May 31, 2011
    Date of Patent: July 22, 2014
    Assignee: DexCom, Inc.
    Inventors: Paul V. Goode, Jr., James H. Brauker, Apurv U. Kamath, James P. Thrower
  • Transcutaneous analyte sensor
    Patent number: 8788007
    Abstract: The present invention relates generally to systems and methods for measuring an analyte in a host. More particularly, the present invention relates to systems and methods for transcutaneous measurement of glucose in a host.
    Type: Grant
    Filed: March 8, 2012
    Date of Patent: July 22, 2014
    Assignee: DexCom, Inc.
    Inventors: James H. Brauker, Apurv Ullas Kamath, Paul V. Goode, Mark Brister
  • System and methods for processing analyte sensor data
    Patent number: 8788006
    Abstract: Systems and methods for processing sensor analyte data, including initiating calibration, updating calibration, evaluating clinical acceptability of reference and sensor analyte data, and evaluating the quality of sensor calibration. During initial calibration, the analyte sensor data is evaluated over a period of time to determine stability of the sensor. The sensor may be calibrated using a calibration set of one or more matched sensor and reference analyte data pairs. The calibration may be updated after evaluating the calibration set for best calibration based on inclusion criteria with newly received reference analyte data. Fail-safe mechanisms are provided based on clinical acceptability of reference and analyte data and quality of sensor calibration. Algorithms provide for optimized prospective and retrospective analysis of estimated blood analyte data from an analyte sensor.
    Type: Grant
    Filed: December 11, 2009
    Date of Patent: July 22, 2014
    Assignee: DexCom, Inc.
    Inventors: Apurv Ullas Kamath, Paul V. Goode, Jr., James H. Brauker
  • Systems and methods for replacing signal artifacts in a glucose sensor data stream
    Patent number: 8777853
    Abstract: Systems and methods for minimizing or eliminating transient non-glucose related signal noise due to non-glucose rate limiting phenomenon such as interfering species, ischemia, pH changes, temperatures changes, known or unknown sources of mechanical, electrical and/or biochemical noise, and the like. The system monitors a data stream from a glucose sensor and detects signal artifacts that have higher amplitude than electronic or diffusion-related system noise. The system processes some or the entire data stream continually or intermittently based at least in part on whether the signal artifact event has occurred.
    Type: Grant
    Filed: April 4, 2012
    Date of Patent: July 15, 2014
    Assignee: DexCom, Inc.
    Inventors: Apurv Ullas Kamath, James H. Brauker, Aarthi Mahalingam, Ying Li