Abstract: Systems and methods for processing sensor data are provided. In some embodiments, systems and methods are provided for calibration of a continuous analyte sensor. In some embodiments, systems and methods are provided for classification of a level of noise on a sensor signal. In some embodiments, systems and methods are provided for determining a rate of change for analyte concentration based on a continuous sensor signal. In some embodiments, systems and methods for alerting or alarming a patient based on prediction of glucose concentration are provided.
Type:
Grant
Filed:
October 24, 2008
Date of Patent:
April 16, 2013
Assignee:
DexCom, Inc.
Inventors:
Mohammad Ali Shariati, Apurv Ullas Kamath, J. Michael Dobbles, Aarthi Mahalingam
Abstract: Disclosed herein are systems and methods for a continuous analyte sensor, such as a continuous glucose sensor. One such system utilizes first and second working electrodes to measure additional analyte or non-analyte related signal. Such measurements may provide a background and/or sensitivity measurement(s) for use in processing sensor data and may be used to trigger events such as digital filtering of data or suspending display of data.
Type:
Grant
Filed:
October 1, 2007
Date of Patent:
April 16, 2013
Assignee:
DexCom, Inc.
Inventors:
Peter C. Simpson, Mark Brister, Matthew Wightlin, Jack Pryor
Abstract: Systems and methods for processing sensor data are provided. In some embodiments, systems and methods are provided for calibration of a continuous analyte sensor. In some embodiments, systems and methods are provided for classification of a level of noise on a sensor signal. In some embodiments, systems and methods are provided for determining a rate of change for analyte concentration based on a continuous sensor signal. In some embodiments, systems and methods for alerting or alarming a patient based on prediction of glucose concentration are provided.
Type:
Grant
Filed:
October 24, 2008
Date of Patent:
April 9, 2013
Assignee:
DexCom, Inc.
Inventors:
Apurv Ullas Kamath, J. Michael Dobbles, Aarthi Mahalingam
Abstract: Systems and methods for minimizing or eliminating transient non-glucose related signal noise due to non-glucose rate limiting phenomenon such as ischemia, pH changes, temperatures changes, and the like. The system monitors a data stream from a glucose sensor and detects signal artifacts that have higher amplitude than electronic or diffusion-related system noise. The system replaces some or the entire data stream continually or intermittently including signal estimation methods that particularly address transient signal artifacts. The system is also capable of detecting the severity of the signal artifacts and selectively applying one or more signal estimation algorithm factors responsive to the severity of the signal artifacts, which includes selectively applying distinct sets of parameters to a signal estimation algorithm or selectively applying distinct signal estimation algorithms.
Type:
Grant
Filed:
February 9, 2011
Date of Patent:
April 2, 2013
Assignee:
DexCom, Inc.
Inventors:
Paul V. Goode, Jr., James H. Brauker, Apurv U. Kamath, James Patrick Thrower, Victoria Carr-Brendel
Abstract: Systems and methods for processing, transmitting and displaying data received from an analyte sensor, such as a glucose sensor, are provided. The data can be displayed on a hand-held display device having a display such as a key fob device including a user interface, such as an LCD and one or more buttons 604 allows a user to view data, and a physical connector, such as USB port.
Abstract: Systems and methods for processing, transmitting and displaying data received from an analyte sensor, such as a glucose sensor, are provided. The data can be displayed on a hand-held display device having a display such as a key fob device including a user interface, such as an LCD and one or more buttons that allows a user to view data, and a physical connector, such as USB port.
Abstract: Systems and methods for processing, transmitting and displaying data received from an analyte sensor, such as a glucose sensor, are provided. The data can be displayed on a hand-held display device having a display such as a key fob device including a user interface, such as an LCD and one or more buttons that allows a user to view data, and a physical connector, such as USB port.
Abstract: Systems and methods of use for continuous analyte measurement of a host's vascular system are provided. In some embodiments, a continuous glucose measurement system includes a vascular access device, a sensor and sensor electronics, the system being configured for insertion into communication with a host's circulatory system.
Type:
Grant
Filed:
March 25, 2008
Date of Patent:
March 12, 2013
Assignee:
DEXCOM, Inc.
Inventors:
Apurv Ullas Kamath, Peter C. Simpson, Mark Brister
Abstract: Systems and methods for processing sensor analyte data, including initiating calibration, updating calibration, evaluating clinical acceptability of reference and sensor analyte data, and evaluating the quality of sensor calibration. During initial calibration, the analyte sensor data is evaluated over a period of time to determine stability of the sensor. The sensor may be calibrated using a calibration set of one or more matched sensor and reference analyte data pairs. The calibration may be updated after evaluating the calibration set for best calibration based on inclusion criteria with newly received reference analyte data. Fail-safe mechanisms are provided based on clinical acceptability of reference and analyte data and quality of sensor calibration. Algorithms provide for optimized prospective and retrospective analysis of estimated blood analyte data from an analyte sensor.
Type:
Grant
Filed:
October 1, 2007
Date of Patent:
March 12, 2013
Assignee:
DexCom, Inc.
Inventors:
Paul V. Goode, James H. Brauker, Apurv U. Kamath
Abstract: Systems and methods for processing sensor analyte data are disclosed, including initiating calibration, updating calibration, evaluating clinical acceptability of reference and sensor analyte data, and evaluating the quality of sensor calibration. The sensor can be calibrated using a calibration set of one or more matched sensor and reference analyte data pairs. Reference data resulting from benchtop testing an analyte sensor prior to its insertion can be used to provide initial calibration of the sensor data. Reference data from a short term continuous analyte sensor implanted in a user can be used to initially calibrate or update sensor data from a long term continuous analyte sensor.
Type:
Application
Filed:
September 7, 2012
Publication date:
March 7, 2013
Applicant:
DexCom, Inc.
Inventors:
Jack Pryor, Apurv Ullas Kamath, Paul V. Goode, James H. Brauker
Abstract: Devices and methods are described for providing continuous measurement of an analyte concentration. In some embodiments, the devices include a membrane that has an interference domain designed to reduce the permeation of one or more interferents.
Type:
Application
Filed:
August 24, 2012
Publication date:
February 28, 2013
Applicant:
DEXCOM, INC.
Inventors:
Jonathan Hughes, Robert J. Boock, Chris W. Dring
Abstract: Devices and methods are described for providing continuous measurement of an analyte concentration. In some embodiments, the devices include a membrane that has an interference domain designed to reduce the permeation of one or more interferents.
Type:
Application
Filed:
August 24, 2012
Publication date:
February 28, 2013
Applicant:
DEXCOM, INC.
Inventors:
Jonathan Hughes, Robert J. Boock, Chris W. Dring
Abstract: Disclosed herein are systems and methods for calibrating a continuous analyte sensor, such as a continuous glucose sensor. One such system utilizes one or more electrodes to measure an additional analyte. Such measurements may provide a baseline or sensitivity measurement for use in calibrating the sensor. Furthermore, baseline and/or sensitivity measurements may be used to trigger events such as digital filtering of data or suspending display of data.
Type:
Grant
Filed:
September 7, 2011
Date of Patent:
February 26, 2013
Assignee:
DexCom, Inc.
Inventors:
Apurv Ullas Kamath, Peter C. Simpson, James H. Brauker, Paul V. Goode, Jr.
Abstract: Systems and methods for dynamically and intelligently estimating analyte data from a continuous analyte sensor, including receiving a data stream, selecting one of a plurality of algorithms, and employing the selected algorithm to estimate analyte values. Additional data processing includes evaluating the selected estimative algorithms, analyzing a variation of the estimated analyte values based on statistical, clinical, or physiological parameters, comparing the estimated analyte values with corresponding measure analyte values, and providing output to a user. Estimation can be used to compensate for time lag, match sensor data with corresponding reference data, warn of upcoming clinical risk, replace erroneous sensor data signals, and provide more timely analyte information encourage proactive behavior and preempt clinical risk.
Type:
Grant
Filed:
October 16, 2008
Date of Patent:
February 12, 2013
Assignee:
DexCom, Inc.
Inventors:
James H. Brauker, Victoria E. Carr-Brendel, Paul V. Goode, Apurv Ullas Kamath, James Patrick Thrower, Ben Xavier
Abstract: Systems and methods for detecting and reporting patterns in analyte concentration data are provided. According to some implementations, an implantable device for continuous measurement of an analyte concentration is disclosed. The implantable device includes a sensor configured to generate a signal indicative of a concentration of an analyte in a host, a memory configured to store data corresponding at least one of the generated signal and user information, a processor configured to receive data from at least one of the memory and the sensor, wherein the processor is configured to generate pattern data based on the received information, and an output module configured to output the generated pattern data. The pattern data can be based on detecting frequency and severity of analyte data in clinically risky ranges.
Type:
Application
Filed:
August 3, 2012
Publication date:
February 7, 2013
Applicant:
DexCom, Inc.
Inventors:
Phil Mayou, Hari Hampapuram, David Price, Keri Weindel, Kostyantyn Snisarenko, Michael Robert Mensinger, Leif N. Bowman, Robert J. Boock, Apurv Ullas Kamath, Eli Reihman, Peter C. Simpson
Abstract: Systems and methods for detecting and reporting patterns in analyte concentration data are provided. According to some implementations, an implantable device for continuous measurement of an analyte concentration is disclosed. The implantable device includes a sensor configured to generate a signal indicative of a concentration of an analyte in a host, a memory configured to store data corresponding at least one of the generated signal and user information, a processor configured to receive data from at least one of the memory and the sensor, wherein the processor is configured to generate pattern data based on the received information, and an output module configured to output the generated pattern data. The pattern data can be based on detecting frequency and severity of analyte data in clinically risky ranges.
Type:
Application
Filed:
August 3, 2012
Publication date:
February 7, 2013
Applicant:
DexCom, Inc.
Inventors:
Phil Mayou, Hari Hampapuram, David Price, Keri Weindel, Kostyantyn Snisarenko, Michael Robert Mensinger, Leif N. Bowman, Robert J. Boock, Apurv Ullas Kamath, Eli Reihman, Peter C. Simpson
Abstract: Systems and methods for detecting and reporting patterns in analyte concentration data are provided. According to some implementations, an implantable device for continuous measurement of an analyte concentration is disclosed. The implantable device includes a sensor configured to generate a signal indicative of a concentration of an analyte in a host, a memory configured to store data corresponding at least one of the generated signal and user information, a processor configured to receive data from at least one of the memory and the sensor, wherein the processor is configured to generate pattern data based on the received information, and an output module configured to output the generated pattern data. The pattern data can be based on detecting frequency and severity of analyte data in clinically risky ranges.
Type:
Application
Filed:
August 3, 2012
Publication date:
February 7, 2013
Applicant:
DexCom, Inc.
Inventors:
Phil Mayou, Hari Hampapuram, David Price, Keri Weindel, Kostyantyn Snisarenko, Michael Robert Mensinger, Leif N. Bowman, Robert J. Boock, Apurv Ullas Kamath, Eli Reihman, Peter C. Simpson
Abstract: Systems and methods for processing sensor data are provided. In some embodiments, systems and methods are provided for calibration of a continuous analyte sensor. In some embodiments, systems and methods are provided for classification of a level of noise on a sensor signal. In some embodiments, systems and methods are provided for determining a rate of change for analyte concentration based on a continuous sensor signal. In some embodiments, systems and methods for alerting or alarming a patient based on prediction of glucose concentration are provided.
Type:
Grant
Filed:
October 24, 2008
Date of Patent:
February 5, 2013
Assignee:
DexCom, Inc.
Inventors:
Apurv Ullas Kamath, Paul V. Goode, James H. Brauker, James P. Thrower
Abstract: The invention provides an implantable membrane for regulating the transport of analytes therethrough that includes a matrix including a first polymer; and a second polymer dispersed throughout the matrix, wherein the second polymer forms a network of microdomains which when hydrated are not observable using photomicroscopy at 400× magnification or less. In one aspect, the homogeneous membrane of the present invention has hydrophilic domains dispersed substantially throughout a hydrophobic matrix to provide an optimum balance between oxygen and glucose transport to an electrochemical glucose sensor.
Abstract: Systems and methods of use for continuous analyte measurement of a host's vascular system are provided. In some embodiments, a continuous glucose measurement system includes a vascular access device, a sensor and sensor electronics, the system being configured for insertion into communication with a host's circulatory system.
Type:
Grant
Filed:
March 25, 2008
Date of Patent:
January 29, 2013
Assignee:
Dexcom, Inc.
Inventors:
Peter C. Simpson, Mark Brister, Jacob S. Leach