Abstract: An apparatus for metered supply of a liquid medicament having a power supply which not only allows the primary battery to be replaced without interrupting the insulin supply, but also makes it possible to bridge uncontrolled short-term interruptions in the current supply or voltage supply resulting from bouncing of the battery contacts, while also providing an adequate emergency power reserve is disclosed.

Abstract: An insertion aid for inserting a cannula of a catheter head into organic tissue, in particular a catheter head for administering a liquid active substance, wherein the insertion aid includes a guide needle that is fixed to a grip section for removably inserting and stabilising the cannula during insertion into the organic tissue and a needle shield, having at least two sections, which is secured in a pivotable manner to the grip section and which encases and shields the guide needle when the insertion aid is separated from the catheter head.

Abstract: A system for recommending insulin bolus quantities to an insulin user includes a display unit and memory unit coupled to a control circuit with a user blood glucose target stored in the memory unit. The control circuit is programmed to receive the user's current blood glucose value, to determine and display via the display unit a recommended correction insulin bolus quantity if the current blood glucose value exceeds the blood glucose target, to compute a difference value as the current blood glucose value less the blood glucose target, and to produce a modified blood glucose target as a sum of the blood glucose target and the difference value for a lock-out time period if the difference value is positive. Additional correction insulin bolus quantities may be recommended during the lock-out time period if the user's current blood glucose value exceeds the modified blood glucose target.

Abstract: A membrane with at least one passage extending through an elastic material of the membrane, wherein when a cannula is inserted in the passage, the passage is expanded and the elastic material presses against the cannula and surrounds the cannula in a seal, wherein the membrane can be compressed relative to the passage, and wherein, in one embodiment, the passage exhibits a cross-sectional area having a long main axis and a short main axis perpendicular to the long main axis. The invention encompasses a membrane-cannula combination for biological and medical uses, and a membrane-connecting device combination for connecting a fluid guide and a catheter.

Abstract: A cannula, for introduction into a body tissue, the cannula flexible after introduction, and rigid below a critical temperature and flexible above the critical temperature. In a method for the introduction of the cannula into the body tissue, the cannula is cooled to a temperature below the critical temperature and introduced into the body tissue. After being introduced, the cannula is brought to a temperature above the critical temperature by warming and thus becomes flexible.

Abstract: A device for administering an injectable product in doses including a casing, a container for the product, accommodated by the casing, from which container product is delivered through an opening of the container by moving a piston accommodated in the container toward the opening, and a drive for causing the delivery of the product wherein the drive moves the container relative to the casing and the piston.

Abstract: A device for the dosed output of a substance, the device involving hydrogel-based osmotic drive, wherein output characteristics of the device, including a time profile, may be adjusted by a user. In some embodiments, the device may be used once and, in other embodiments, it may be used several times.

Abstract: A system for removing or tranferring a pharmaceutical product from a reservoir including an ampoule with a moveable piston therein and an adaptor which includes, generally along a longitudinal axis, a reservoir connector and an ampoule connector for coupling to the ampoule, wherein the ampoule connector includes at least one locking mechanism which, in a side wall, includes a resilient element generally corresponding to a portion of the side wall which extends along the periphery thereof and, at opposing ends, merges with the side wall.

Abstract: A system for positioning and inserting insertion means into tissue includes an insertion head and an inserter. The insertion head includes a base with a lower side positionable on tissue; and an insertion means movably mounted by the base, which is movable from a protective position where a free end of the insertion means is short of the lower side, into an insertion position where the free end protrudes beyond the lower side of the base. The inserter includes an inserter casing having a lower side with an opening for the insertion head; a holding means, coupled to the inserter casing for holding the insertion head in an initial position; a drive configured to move the insertion head out of the initial position in an advancing direction; and an activating member movable relative to the holding means and operable such that the insertion means is moved into the insertion position.

Abstract: An injection needle, for injection into a body tissue, is flexible in the introduced or post-inserted state and comprises a channel for the introduction of a fluid. The injection needle is at least partly made from at least one material which is rigid in one state and flexible in a second state. Alternatively or concurrently, the injection needle is rigid on application of a force to the needle along the longitudinal direction of a needle longitudinal axis and is flexible on application of a force in the radial direction relative to the needle longitudinal axis.

Abstract: A system for removing or transferring a pharmaceutical product from a reservoir including an ampoule with a moveable piston therein and an adaptor which includes, generally along a longitudinal axis, a reservoir connector and an ampoule connector for coupling to the ampoule, wherein the ampoule connector includes at least one locking mechanism which, in a side wall, includes a resilient element generally corresponding to a portion of the side wall which extends along the periphery thereof and, at opposing ends, merges with the side wall.

Abstract: A method for diabetes care, the method (which also may be referred to as, involve or incorporate at least one of a tool, device or program) allowing for the characterization of the relevance of errors of parameters affecting glucose concentration on a postprandial glucose concentration outcome for a person with diabetes mellitusm, wherein the method involves at least one of sensing, determining, calculating, predicting, describing and communicating the effects of potential errors of parameters affecting glucose concentration on postprandial glucose concentration values within a clinically relevant glucose range.

Abstract: An administering device with an osmotic drive for administering an injectable product includes a housing with a first chamber containing a solvent, a second chamber containing a solution and a product chamber for accommodating the product. A semi-permeable membrane is disposed between the first chamber and the second chamber. The second chamber is adjoined by a delivery means for delivering product out of the product chamber. A triggering device for triggering the osmotic drive includes an impermeable separating means between the first chamber and the second chamber. The delivery means is slidable relative to the housing along a longitudinal axis of the housing.

Abstract: An insertion head for medical or pharmaceutical applications includes a base having a lower side positionable on organic tissue; an insertion means movably mounted by the base and insertable into the tissue; where the insertion means is movable relative to the base from a protective position in which a free end of the insertion means is short of the lower side of the base, into an insertion position in which the free end protrudes beyond the lower side; and a receptacle that is open towards the lower side of the base and that can be detached from the base, and which accommodates at least the free end of the insertion means in its protective position.

Abstract: An insertion head for medical or pharmaceutical applications includes a base having a lower side which can be positioned on organic tissue; an insertion means movably mounted by the base and insertable into the tissue; where the insertion means is movable relative to the base from a protective position in which a free end of the insertion means is short of the lower side of the base, into an insertion position in which the free end protrudes beyond the lower side; a handle which projects from the base and includes a first handle component and a second handle component movable relative to the base and the first handle component; and a coupling that transmits a movement of the second handle component into a movement of the insertion means.

Abstract: An insertion device for inserting an injection needle into a tissue including a needle holder carrying the injection needle and a protection device for covering the injection needle after the removal thereof from the tissue wherein the needle holder is mounted to move along the needle axis in relation to the protection device and for insertion of the injection needle the needle holder and protection device are moved more closely together and wherein at least one catch is provided on at least one of the needle holder and protection device, which firmly engages the needle holder with the protection device in an extended relative position. The invention encompasses a catheter head having a base body, a flexible cannula extending from the base body and the insertion device with the protection device.

Abstract: A multi-layered plastic body for containing, storing or conducting a medical, diagnostic, pharmaceutical, cosmetic or other product, the plastic body including a first layer made of a stress fracture resistant plastic material, and at least a second layer adjacent to the first layer and made of a plastic material exhibiting a lower resistance to stress fractures than the first plastic material. The invention encompasses a suitable method of making the body.

Abstract: The invention relates to measuring the concentration of analytes with the aid of an oxidase in an immersion sensor situated in a fluid or in a matrix containing fluid. Oxygen diffuses into the enzyme layer from within, from a gas-filled space connected to the atmosphere and/or to an oxygen reservoir. This enables oxygen saturation of the oxidase in a low-oxygen or oxygen-free medium and/or at high analyte concentrations. The analyte diffuses into the enzyme layer in a channel or a number of channels which contain(s) water and limit(s) diffusion, wherein the channel/channels on the surface of the sensor is/are filled with a protein-impermeable, hydrophilic matrix. By increasing the channel cross-section on the surface of the sensor and/or by connecting the channel/channels to a protein-impermeable, porous, hydrophilic layer on the surface of the sensor, the effect of outer deposits on the diffusion resistance of the analyte is reduced.

Abstract: A catheter head for medical and pharmaceutical applications, including a base body which may be positioned on organic tissue and a connecting body, serving as fluid connector for the base body, which has a fluid channel to form the fluid connection. The base body and the connecting body are detachably connected to each other and the base body includes: a) a housing b) a cannula, extending from the housing for introduction into the tissue, c) a seal element, retained by the housing, which has a connector face on which or by means of which the fluid channel of the connecting body may be hydraulically connected to the cannula, and d) a closing element, mounted on the housing which may be displaced relative to the sealing element and seals the sealing face of the sealing element in a closed position and opens the connecting body for the fluid channel in an open position.

Abstract: A device for the metered administration of a fluid drug. The device has a container having a piston for administering the fluid drug through an outlet of the container, a catheter connected to the outlet of the container, the catheter having a front end facing away from the outlet and being connected to an injection needle, and a valve positioned between the outlet and the injection needle in a flow cross section of the fluid drug, the valve having an inlet end adjacent the outlet and an outlet end adjacent the injection needle, wherein the valve permits flow of the fluid drug through the valve from the outlet to the injection needle when a fluid pressure exerted on the inlet end of the valve exceeds a pressure on the inlet end caused by the dead weight of the fluid drug.