Abstract: A method for determining a predicted lesion size formed in a tissue by receiving or calculating a measure of contact force between the electrode and the tissue, determining a tissue characterization, and calculating the predicted lesion size using both the measure of contact force and the tissue characterization. A system comprising an electronic control unit configured to receive or determine a measure of contact force between the electrode and the tissue, characterize the tissue based on both the measure of impedance and the measure of contact force, and cause the tissue characterization to be either (a) presented to a user, or (b) applied to calculate a metric and cause the metric to be presented to the user.

Abstract: A loudspeaker arrangement for a seat within a motor vehicle utilizes one or more localized sound output ports for low frequency sound reproduction. A housing, such as an enclosure, substantially surrounds a loudspeaker. One or more audio transmission line channels acoustically interconnect the interior of the enclosure to one or more sound output ports. The enclosure is situated below, behind, or in some fixed location around or within a vehicle seat. The sound outputs ports are situated at or near a headrest such that the output ports are located substantially less than a wavelength of sound at the highest operating frequency from either ear of the seat's occupant. The acoustic response and resonances of a 1) rear enclosure, 2) a front vented enclosure, 3) a loudspeaker, and 4) an audio transmission path from the enclosure to one or more output ports are used to provide localized low frequency sound reproduction.

Abstract: A prosthetic heart valve includes a support structure and a valve assembly disposed within the support structure, the valve assembly including a plurality of leaflets. Each leaflet is formed from a predetermined leaflet material. Some leaflet materials include a metal body with a plurality of openings. The metal body may be coated with a polymer. Other leaflet materials include natural mammalian tissue subjected to a plastination preservation process.

Abstract: A medical device including a removable frame and biomaterial cover, methods of assembling and using the same, and a delivery system including the same are described herein. The medical device includes a frame having proximal and distal ends, the frame including a proximal disc at the proximal end, a distal disc at the distal end, and a connecting segment having a proximal end and a distal end connecting the proximal and distal discs. Each of the proximal and distal discs includes a respective plurality of prongs and has a maximum cross-sectional dimension larger than the connecting segment. The medical device further includes at least one biomaterial cover including an outer section and an inner section defining a cavity therebetween, wherein at least one of the proximal and distal discs of the frame is positioned in the cavity.

Abstract: The invention pertains to the field of computer implemented or computer aided methods for systematic search (contrary to trial and error) for materials (material science, material informatics) in relation to structural/mechanical properties and preferably a both radiation shielding and structural/mechanical properties.

Abstract: The invention relates to ablation catheter electrodes that solve in part the problem of tissue charring during radiofrequency ablation. The electrode assemblies of the invention include passageways that lead from the inner lumen of the assemblies to the surface of the assemblies, wherein the passageways have a smooth conjunction with the outer surface. These smooth conjunctions comprise rounded edges or are chamfered. In the case of rounded edges, the rounded edges can have fixed radii of about 0.002? to about 0.008?.

Abstract: A delivery device for delivering a pacing lead to the His bundle of a patient's heart includes an elongated sheath having a distal end, and a plurality of mapping electrodes positioned at the distal end. The distal end of the sheath may have a distal tip, and the mapping electrodes may include two electrodes that diametrically oppose one another at a position spaced from the distal tip of the sheath. The sheath includes a plurality of flexible sections spaced apart from one another, and a pull wire that causes the sheath to deflect from a straight configuration to a dual hinged curved configuration that positions the electrodes in the vicinity of the bundle of His.

Abstract: A printed sign that includes a material printed with visual content. The material is rectangular and folded along an x-axis forming a first part and a second part. Prior to the folding, the x-axis divides the material horizontally and a y-axis divides the material vertically. A u-stake is oriented at the x-axis of the material in contact with an inner surface of the first part and an inner surface of the second part. The visual content appears on an outer surface of the first part and on an outer surface of the second part. Either the first part or the second part comprises an even number of sets of holes and a u-stake is threaded through each hole of the even number of the sets of holes and the third portion is oriented adjacent to the x-axis of the material.

Abstract: Techniques are provided for candidate screening for a target therapy. A plurality of medical codes corresponding to patient billing data are identified. A candidate classification model for a target therapy is generated by selecting a set of medical codes from the plurality of medical codes and assigning a weight to each medical code selected. The candidate classification model is applied to patient billing data for a plurality of patients to generate a set of target therapy scores. The patient billing data includes associations between one or more patients of the plurality of patients and one or more medical codes of the plurality of medical codes. Each target therapy score corresponds to a patient of the plurality of patients, and is calculated based on weights for one or more medical codes associated with the patient.

Abstract: A head up display mirror holder arrangement for a motor vehicle includes a picture generation unit producing a light field. A mirror reflects the light field such that the light field is visible to the driver as a virtual image. A mirror holder has two opposite ends and an activation feature. The two opposite ends are aligned along a rotational axis of the mirror. The mirror holder retains the mirror. Each of two bushings is coupled to a respective opposite end of the mirror holder. A calibration switch has minimum proximity to the activation feature of the mirror holder.

Abstract: Examples of the disclosure relate to example systems and methods for operating wireless headset system for a vehicle. An example system includes a first wireless chipset to handle communication with a smartphone, and a second wireless chipset to handle communication with a headset. The example system also includes a processor configured to execute a first virtual machine to control the first wireless chipset and a second virtual machine to control the second wireless chipset.

Abstract: A catheter including a loop member adjustment mechanism for adjusting a diameter of a loop member is provided. The catheter further includes a longitudinally-extending catheter shaft including a proximal end portion and a distal end deflectable portion, wherein the distal end deflectable portion includes the loop member. The loop adjustment mechanism includes a loop member pull wire, wherein a distal end of the loop member pull wire is attached to the loop member, and a sliding member, located within the handle, wherein the sliding member is configured to translate within the handle, and wherein a proximal end of the pull wire is attached to the sliding member.

Abstract: In various embodiments, the beam parameter product and/or beam shape of a laser beam is adjusted by coupling the laser beam into an optical fiber of a fiber bundle and directing the laser beam onto one or more in-coupling locations on the input end of the optical fiber. The beam emitted at the output end of the optical fiber may be utilized to process a workpiece.

Abstract: In various embodiments, laser delivery systems feature variable polarizers and beam shapers for altering the polarization and/or shape of the output beam for processing of various materials. The polarization and/or shape of the beam may be varied based on one or more characteristics of the workpiece.

Abstract: According to one aspect of the disclosure, a prosthetic heart valve includes a collapsible and expandable frame that includes a central portion, and atrial and ventricular portions flaring outwardly from the central portion. A prosthetic valve is housed within the frame. An outer skirt is disposed on an outer surface of the frame, the outer skirt having a first end portion having a first attachment to the atrial portion or the ventricular portion, a second intermediate portion having a second attachment to the frame adjacent the central portion, and a third intermediate portion having a third attachment to the frame adjacent the central portion. Upon transition of the frame from the expanded condition to the collapsed condition, the first attachment does not translate relative to the frame, while the second and third attachments do translate relative to the frame.

Abstract: Unidirectional transparent projectile penetration resistant panel assemblies and bidirectional opaque projectile penetration resistant assemblies and systems and methods of forming and mounting the same relative to underlying support structures.

Abstract: A deflectable catheter shaft section is disclosed comprising an elongated body extending along a longitudinal axis with a distal end and a proximal end. First and second pull wires can extend along the elongated body and can have a proximal end and a distal end. First and second pull wire liners can be disposed over a portion of one of the first and second pull wires, respectively. Each of the first and second pull wires can have a proximal end and a distal end. A first gap can exist between the proximal end of the first pull wire liner and the proximal end of the elongated body and a second gap can exist between the proximal end of the second pull wire liner and the proximal end of the elongated body.

Abstract: A prosthetic heart valve system may include a collapsible anchor frame which may include a support frame that has a central portion, and atrial and ventricular portions flared radially outwardly from the central portion. The atrial and ventricular portions may be sized to sandwich or clamp an annulus of the heart valve. An atrial sheet may be coupled to the atrial portion of the support frame and may extend radially inwardly to a central aperture in the atrial sheet, the atrial sheet being formed of a material that is substantially impermeable to blood. The system may include a leaflet support structure, an inflow end of the leaflet support structure coupled to the atrial sheet. The atrial sheet may define an opening positioned radially outside of the leaflet support structure so that blood flowing around an exterior of the leaflet support structure passes through the opening.

Abstract: A monitoring, managing and protecting system is provided that includes a monitoring probe working in conjunction with an ablating device. The probe is configured to be positioned in close proximity to a region of non-targeted tissue proximate an ablation site of targeted tissue and to be operatively connected to an electrical response assessment system or component. The probe includes an elongate shaft having proximal and distal ends, with a handle disposed at the proximal end thereof and a tissue monitoring and protecting apparatus disposed at the distal end thereof. The ablating device includes an elongate shaft having proximal and distal ends, with a handle mounted at the proximal end thereof and an ablation element mounted at the distal end thereof. The monitoring probe measures electrical characteristics of the non-targeted tissue and/or of the tissue between the monitoring electrode and the ablation electrode.

Abstract: Braided occluding devices having an access passage and methods including the same are described herein. The occluding device includes a braided frame which includes. The braided frame includes an annular distal disc portion, a waist member, and an annular proximal disc portion defining a passageway through the braided frame. The braided frame is formed with a closed end braid.