Abstract: A solid dosage form for oral administration comprising azithromycin in an amount below that which causes gastrointestinal side effects, which dosage form is a controlled release dosage form.
Type:
Application
Filed:
January 25, 2012
Publication date:
May 17, 2012
Applicant:
Dow Pharmaceutical Sciences, Inc.
Inventors:
Radhakrishnan Pillai, Pramod Sarpotdar, David W. Osborne, Gordon J. Dow
Abstract: Powder containing benzoyl peroxide is readily wetted by contacting the powder with a liquid containing one or more of a polyol, a polyol, ether, and a low-carbon organic alcohol.
Abstract: Azithromycin has increased efficacy in treating acne and other skin conditions when administered systemically at low doses, below those previously known to produce a clinical antibiotic effect.
Type:
Grant
Filed:
September 4, 2008
Date of Patent:
March 27, 2012
Assignee:
Dow Pharmaceutical Sciences, Inc.
Inventors:
Gordon Jay Dow, Bhaskar Chaudhuri, David Wade Osborne, Barry Calvarese
Abstract: A solid dosage form for oral administration comprising azithromycin in an amount below that which causes gastrointestinal side effects, which dosage form is a controlled release dosage form.
Type:
Grant
Filed:
December 17, 2007
Date of Patent:
February 28, 2012
Assignee:
Dow Pharmaceutical Sciences, Inc.
Inventors:
Radhakrishnan Pillai, Pramod Sarpotdar, David W. Osborne, Gordon J. Dow
Abstract: Methods and compositions for treating disorders of the nail and nail bed. Such compositions contain a vehicle in which all components of the composition are dissolved, suspended, dispersed, or emulsified, a non-volatile solvent, a wetting agent, and a pharmaceutically active ingredient that is soluble in the non-volatile solvent and/or a mixture of the vehicle and the non-volatile solvent, which composition has a surface tension of 40 dynes/cm or less and has continuing spreadability, and which composition is effective in treating a disorder of the nail or nail bed.
Abstract: Methods and compositions for treating disorders of the nail and nail bed. Such compositions contain a vehicle in which all components of the composition are dissolved, suspended, dispersed, or emulsified, a non-volatile solvent, a wetting agent, and a pharmaceutically active ingredient that is soluble in the non-volatile solvent and/or a mixture of the vehicle and the non-volatile solvent, which composition has a surface tension of 40 dynes/cm or less and has continuing spreadability, and which composition is effective in treating a disorder of the nail or nail bed.
Abstract: The combination of any two of a polyol, a polyol ether, and a low carbon organic alcohol provides a synergistic effect on the solubility of azole compounds, such as metronidazole, in aqueous fluid.