Abstract: The present invention relates to pemetrexed disodium substantially free from specific process-related impurities, and processes for the preparation thereof.
Type:
Application
Filed:
February 13, 2012
Publication date:
June 27, 2013
Applicants:
DR. REDDY'S LABORATORIES, INC., DR. REDDY'S LABORATORIES LTD.
Abstract: The invention describes a method for protein purification. More particularly, the invention relates to a purification process comprising protein A chromatography and anion exchange chromatography wherein protein A chromatography eluate is further purified by anion exchange chromatography at similar pH or at a pH less than or equal to 6.
Type:
Application
Filed:
December 28, 2010
Publication date:
May 9, 2013
Applicants:
DR. REDDY'S LABORATORIES, INC., DR. REDDY'S LABORATORIES LTD.
Inventors:
Samir Kulkarni, Satyam Subrahmanyam, Y. Raghvendra, Prashant Kardekar
Abstract: Single phase pharmaceutical compositions for topical application, in addition to kits and methods of use and administration are provided. The compositions comprise a biologically active agent; a delivery vehicle comprising at least a non-polymeric crystallization inhibitor and a film-former; and a volatile solvent; wherein the biologically active agent is present in the composition in a subsaturated state, the biologically active agent is present in the delivery vehicle in a supersaturated state, and the crystallization inhibitor is capable of delaying crystallization of the biologically active agent in the delivery vehicle. Biologically active agents include terbinafine and acyclovir. Treatments for onychomycosis and Varicella zoster infection, HSV-I infection or HSV-2 infection are provided.
Type:
Grant
Filed:
June 14, 2007
Date of Patent:
April 30, 2013
Assignees:
Dr. Reddy's Laboratories, Inc., Dr. Reddy's Laboratories, Ltd.
Inventors:
Ake Lindahl, Birgitta Svensson, Anna Holmberg, Johan Engblom
Abstract: Sustained release formulations comprising donepezil, or its pharmaceutically acceptable salts, and methods of preparing the sustained release formulations.
Type:
Application
Filed:
December 3, 2010
Publication date:
March 7, 2013
Applicants:
DR. REDDY'S LABORATORIES, INC., DR. REDDY'S LABORATORIES LTD.
Abstract: The application provides formulations for the topical administration of an active agent comprising at least one steroid, in the form of topical sprays that are propellant-free, and/or substantially non-foaming, and/or alcohol-free. The present application also provides processes for preparing such compositions and methods of using them in management of skin diseases or disorders such as psoriasis, dermatoses, and other associated skin diseases or disorders.
Type:
Application
Filed:
August 31, 2010
Publication date:
August 23, 2012
Applicants:
DR. REDDY'S LABORATORIES, INC., DR. REDDY'S LABORATORIES LTD.
Abstract: Preparation and isolation of amino vinyl cyclopropane carboxylic acid derivatives and salts thereof, methods of resolving enantiomers, and methods of identifying compositions and/or enzymes that are capable of resolving racemic or partially enantiomerically enriched mixtures.
Type:
Application
Filed:
January 2, 2012
Publication date:
May 31, 2012
Applicants:
DR. REDDY'S LABORATORIES, INC., DR. REDDY'S LABORATORIES LTD.
Inventors:
Ian N. Taylor, Michael C. Lloyd, Adrian Heseltine
Abstract: The application relates to processes for preparing fipamezole and its pharmaceutically acceptable salts, and intermediates thereof. It also provides intermediate compounds of Formula III and Formula IV, and processes for their preparation.
Type:
Application
Filed:
January 31, 2012
Publication date:
May 24, 2012
Applicants:
DR. REDDY'S LABORATORIES, INC., DR. REDDY'S LABORATORIES LTD.
Inventors:
Ranjan Bhowmik Dipal, Lingam Yedugani, Raghavndra Rao Kamaraju, Subba Rao Jammula, Swapna Manikonda, Vilas H. Dahanukar
Abstract: Methods of producing compositions of trans-4-amino-2-cyclopentene-1-carboxylic acid derivatives are described. Also described is an amine salt of a compound having formula A, having components present in both cis and trans structures.
Type:
Application
Filed:
January 2, 2012
Publication date:
April 26, 2012
Applicants:
DR. REDDY'S LABORATORIES, INC., DR. REDDY'S LABORATORIES LTD.
Inventors:
Richard Lloyd, Justine Ann Peterson, Mark Jackson
Abstract: The present application relates to processes for the preparation and purification of decitabine structurally represented by formula (I): and to processes for the preparation of a crystalline form of decitabine.
Type:
Application
Filed:
October 27, 2011
Publication date:
February 23, 2012
Applicants:
DR. REDDY'S LABORATORIES, INC., DR. REDDY'S LABORATORIES LTD.
Abstract: Pharmaceutical formulations comprising multiple drugs, for treating or preventing cardiovascular disease. Embodiments are capsules containing individual drugs, or combinations of drugs, in the form of small tablets.
Type:
Application
Filed:
October 28, 2011
Publication date:
February 23, 2012
Applicants:
Dr. Reddy's Laboratories, Inc., Dr. Reddy's Laboratories Ltd.
Abstract: Compounds of formula (I) are agonists of PPAR?, useful for the treatment of respiratory disease; formula (I): wherein R1, R2 or R3 each independently represents halo, cyano, nitro, amino, alkyl, haloalkyl, alkoxy, haloalkoxy, carboxylic acid or an ester or amide thereof; R4 represents hydrogen or alkyl; m, n or p independently represents 0, 1, 2 or 3.
Type:
Application
Filed:
December 23, 2009
Publication date:
February 16, 2012
Applicants:
Pulmagen Therapeutics (Inflammation) Limited, Dr. Reddy's Laboratories LTD
Abstract: The present invention relates to docetaxel and processes for preparing docetaxel, including process-related intermediates. The present invention also relates to processes for preparing substantially pure docetaxel and intermediates.
Type:
Application
Filed:
May 20, 2011
Publication date:
November 10, 2011
Applicants:
DR. REDDY'S LABORATORIES, INC., DR. REDDY'S LABORATORIES LTD.
Abstract: Pharmaceutical compositions comprising a plurality of formulated particles containing at least one active ingredient and at least one pharmaceutically acceptable excipient, granulated with a granulating composition containing at least one pharmaceutical excipient.
Type:
Application
Filed:
June 10, 2011
Publication date:
September 29, 2011
Applicants:
DR. REDDY'S LABORATORIES LTD., DR. REDDY'S LABORATORIES, INC.