Patents Assigned to Drexel University
  • Patent number: 10538431
    Abstract: The present invention is directed to crystalline solids having an empirical formula of M2A2X, wherein M is at least one Group IIIB, IVB, VB, or VIB metal, preferably Cr, Hf, Sc, Ti, Mo, Nb, Ta, V, Zr, or a combination thereof; wherein A is Al, Ga, Ge, In, Pb, or Sn, or a combination thereof; and each X is CxNy, where x+y=1. In some particular embodiments, the crystalline composition has a unit cell stoichiometry of Mo2Ga2C.
    Type: Grant
    Filed: March 1, 2016
    Date of Patent: January 21, 2020
    Assignee: Drexel University
    Inventors: Michel W. Barsoum, Chunfeng Hu
  • Patent number: 10537403
    Abstract: A wearable, wireless and battery-free continuous health monitor includes an RFID tag used as an On-Off Keying Device to measure the heart rate. The tag's returned signal strength variations are used to calculate the respiration rate. Machine learning algorithms are employed to determine the health parameters.
    Type: Grant
    Filed: May 23, 2016
    Date of Patent: January 21, 2020
    Assignee: Drexel University
    Inventors: Shrenik Vora, Timothy Kurzweg
  • Patent number: 10532134
    Abstract: In described embodiments, the present invention includes a magnesium-based composite material formed from a plurality of ?-phase magnesium grains; and a ?-alloy phase comprising magnesium and nano-diamond and/or and phosphate containing nanoparticles, the ?-alloy phase surrounding each of the plurality of magnesium grains. A method of manufacturing a composite material is also disclosed.
    Type: Grant
    Filed: April 18, 2013
    Date of Patent: January 14, 2020
    Assignee: Drexel University
    Inventors: Gongyao Zhou, Haibo Gong, Donggang Yao
  • Patent number: 10527625
    Abstract: One or more aqueous, near infrared emitting, high yield, highly photoluminescent, stable quantum dots conjugated to one or more biomarkers specific moieties. The conjugated quantum dots have an enhanced detection sensitivity and selectivity and may be formed using a novel and efficient method for conjugating one or more biomarker specific moieties to the quantum dots. The invention is further directed to a method for using the conjugated quantum dots for cancer detection in the margin of excised tissue.
    Type: Grant
    Filed: July 6, 2016
    Date of Patent: January 7, 2020
    Assignee: Drexel University
    Inventors: Wei-Heng Shih, Wan Y. Shih, Giang Au, Ari D. Brooks, Vanlila K. Swami
  • Patent number: 10517967
    Abstract: An aqueous approach to synthesize capped SnS quantum dots (QDs) followed by optional capping molecule extension by attaching one or more extending molecules to the capping molecule via peptide bond formation at elevated temperature. The capped SnS QDs may have a capping molecule:Sn:S molar ratio of 16:3:1 to 16:12:1. A suspension of SnS QDs was heat-treated at 200° C. for 0.5-4 hrs. The obtained SnS QDs showed an NIR emission peak at 820-835 nm with an excitation wavelength at 690 nm. The as synthesized SnS QDs were found to have high positive zeta potential of ˜30 mV and thus were toxic to cells. By neutralizing the SnS QDs the cytotoxicity was reduced to an accepted level. The heat-treatment step can be obviated by adding a glycerol solution containing S2? anions and capping molecule to a glycerol solution of Sn2+ ions.
    Type: Grant
    Filed: December 22, 2017
    Date of Patent: December 31, 2019
    Assignee: Drexel University
    Inventors: Wei-Heng Shih, Wan Y. Shih, Song Han, Xiaomin Niu, Shi Fang
  • Patent number: 10517933
    Abstract: The invention includes a method of preventing or treating metastasis in a subject diagnosed with prostate cancer. In certain embodiments, the metastasis comprises bone cancer. In other embodiments, the subject suffers from castration-resistant prostate cancer.
    Type: Grant
    Filed: May 11, 2016
    Date of Patent: December 31, 2019
    Assignee: Drexel University
    Inventors: Alessandro Fatatis, Danielle Jernigan, Kristina Susan Shahriari, Fei Shen
  • Publication number: 20190392094
    Abstract: The constrained watershed boundary (CWB), defined as a polygon containing all the flow direction grid cells with a surface flow distance less than a user prescribed threshold uses an algorithm that builds upon the HSM algorithm proposed and augments the data structure with a flow distance grid calculated directly from the original flow direction grid.
    Type: Application
    Filed: June 24, 2019
    Publication date: December 26, 2019
    Applicant: Drexel University
    Inventors: Scott Haag, Ali Shokoufandeh
  • Publication number: 20190393360
    Abstract: The increasing power density and, therefore, current consumption of high performance integrated circuits (ICs) results in increased challenges in the design of a reliable and efficient on-chip power delivery network. In particular, meeting the stringent on-chip impedance of the IC requires circuit and system techniques to mitigate high frequency noise that results due to resonance between the package inductance and the onchip capacitance. In this paper, a novel circuit technique is proposed to suppress high frequency noise through the use of a hyperabrupt junction tuning varactor diode as a decoupling capacitor for noise critical functional blocks. With the proposed circuit technique, the voltage droops and overshoots on the onchip power distribution network are suppressed by up to 60% as compared to MIM or deep trench decoupling capacitors of the same capacitance.
    Type: Application
    Filed: June 21, 2019
    Publication date: December 26, 2019
    Applicant: Drexel University
    Inventors: Divya Pathak, Ioannis Savidis
  • Patent number: 10515483
    Abstract: Presenting a visualization of antenna radiation patterns may include sending a request to a server for up-to-date information regarding an antenna mode; receiving the request at the server and reading a register value for the antenna mode; responding, by the server, with updated antenna mode information; and overlaying antenna radiation patterns on an image based on the mode information.
    Type: Grant
    Filed: December 1, 2016
    Date of Patent: December 24, 2019
    Assignee: Drexel University
    Inventors: Kapil R. Dandekar, Cem Sahin, Logan J. Henderson, Danh H. Nguyen, James J. Chacko, Xaime Rivas Rey
  • Publication number: 20190375761
    Abstract: The present invention includes novel RAD52 inhibitors for preventing or treating cancers in a subject in need thereof. The present invention further includes a method of preventing or treating cancers in a subject in need thereof, the method comprising administering to the subject an effective amount of a compound of the invention. In certain embodiments, the subject is further administered at least one additional therapeutic agent.
    Type: Application
    Filed: August 21, 2019
    Publication date: December 12, 2019
    Applicant: DREXEL UNIVERSITY
    Inventor: Alexander V. MAZIN
  • Patent number: 10499838
    Abstract: A system, device and methods for quantitatively monitoring and evaluating changes in water and hemoglobin content in the brain in a non-invasive manner are provided. The system may be used for real-time detection and monitoring of brain edema and/or for an assessment of cerebral autoregulation.
    Type: Grant
    Filed: April 23, 2016
    Date of Patent: December 10, 2019
    Assignee: Drexel University
    Inventors: Meltem Izzetoglu, Juan Du, Baruch Ben Dor
  • Patent number: 10500407
    Abstract: Disclosed herein are atmospheric pressure pin-to-hole pulsed spark discharge devices and methods for creating plasma. The devices include a conduit for fluidically communicating a gas, a plasma, or both, therethrough, portion of the conduit capable of being connected to a gas supply, and a second portion of the conduit capable of emitting a plasma; a positive electrode comprising a sharp tip; and a ground plate electrode. Disclosed are methods for treating a skin ulcer using non-thermal plasma include flowing a gas through a cold spark discharge zone simultaneously with the creation of a pulsed spark discharge to give rise to a non-thermal plasma emitted from a conduit, the non-thermal plasma comprising NO; and contacting a skin ulcer with said non-thermal plasma for sufficient time and intensity to give rise to treatment of the skin ulcer.
    Type: Grant
    Filed: October 25, 2016
    Date of Patent: December 10, 2019
    Assignee: Drexel University
    Inventors: Danil V. Dobrynin, Alexander Fridman, Young I. Cho, Gregory Fridman, Gennady Friedman
  • Publication number: 20190373463
    Abstract: A physical layer based technique secures wireless communication between a transmitter and receiver. The technique involves obfuscating the preamble data of the baseband signal through unique keys that are generated at the transmitter and the receiver based on channel characteristics known only to them.
    Type: Application
    Filed: January 15, 2018
    Publication date: December 5, 2019
    Applicant: Drexel University
    Inventors: James J. Chacko, Kapil R. Dandekar, Marko Jacovic, Kyle Joseph Juretus, Nagarajan Kandasamy, Cem Sahin, Ioannis Savidis
  • Publication number: 20190371114
    Abstract: A system for delivering physical therapy to a user includes an active video gaming system that has a motion detector capable of detecting the physical motions of a user. The system includes parameters related to movement restrictions that a user may have and the system creates a gaming environment based on the parameters.
    Type: Application
    Filed: February 12, 2018
    Publication date: December 5, 2019
    Applicant: Drexel University
    Inventors: Paul J. Diefenbach, Robert C. Gray, Timothy J. Day, Margaret E. O'Neil
  • Publication number: 20190373458
    Abstract: A key-based interleaver for enhancement the security of wireless communication includes a physical layer communication channel key to provide security even when the software encryption key is compromised. A method of creating a secure communication link using a physical layer interleaving system includes implementing a key policy implementation that utilizes temporal dependency and interleaving bits using a flexible inter and intra-block data interleaver.
    Type: Application
    Filed: June 5, 2019
    Publication date: December 5, 2019
    Applicant: Drexel University
    Inventors: Kapil R. Dandekar, James J. Chacko, Kyle Joseph Juretus, Marko Jacovic, Cem Sahin, Nagarajan Kandasamy, Ioannis Savidis
  • Patent number: 10488368
    Abstract: An inventive approach is disclosed to integrate Digital Image Correlation (DIC) with the Acoustic Emission method that may be used for structural health monitoring and assessment of critical structural components in civil, mechanical, and aerospace industries. The inventive approach relies on passively recording acoustic emission across the specimen being tested and activating the DIC cameras automatically to measure deformation on the specimen's surface. The resulting acousto-optic system can be used to determine damage initiation, progressive damage development, identify critical regions and make lifetime predictions of the tested specimen.
    Type: Grant
    Filed: October 17, 2014
    Date of Patent: November 26, 2019
    Assignee: Drexel University
    Inventors: Antonios Kontsos, Ivan Bartoli, Prashanth Abraham Vanniamparambil
  • Patent number: 10466096
    Abstract: A sensing method is based on using a special fiberoptic probe for detection of acoustic/ultrasound pressure in an immersion medium. The developed system is highly sensitive in detecting ultrasound waves up to 100 MHz, for imaging of micro structures and more. For applications up to 100 MHz, without spatial averaging corrections, the probe tip is modified by reducing the fiber diameter to 7 um or less. Also, to maximize acousto-optic interaction, the probe tip, not just its end face, may be coated with a thin layer of metallic material. This thin film coating satisfies partial transparency of the metallic coating. The coating thickness may range from 2 nm to 10 nm or others depending on the type of the coating material. The probe detects the pressure of acoustic and/or ultrasound waves propagating within an immersion medium, whenever the probe tip is immersed inside the medium, and having a reasonable immersion contact surface.
    Type: Grant
    Filed: April 3, 2017
    Date of Patent: November 5, 2019
    Assignee: Drexel University
    Inventors: Mahmoud A. El-Sherif, Afshin S. Daryoush, Peter A. Lewin, Rupa Gopinath Minasamudram
  • Patent number: 10466194
    Abstract: One embodiment is a biochip having an array of biosensors for quantitative determination of protein-protein and/or antibody-antigen interactions. The array comprises at least two biosensors formed on a substrate. The biosensors can be used to detect either the same or different analytes. The biosensors may be acoustical transducers operated in the thickness shear mode of vibration, wherein the density, viscosity, and elasticity at the sensor interface can be ascertained. Additionally, a series of fluidic channels are etched to the same depth as the biosensors. The fluidic channels serve to efficiently deliver the sample to the biosensors. One or more biochips can be housed within an enclosure.
    Type: Grant
    Filed: February 11, 2016
    Date of Patent: November 5, 2019
    Assignee: Drexel University
    Inventors: Johann deSa, Qiliang Zhang, Ryszard Lec, Ertan Ergezen
  • Patent number: 10466784
    Abstract: A wearable device includes: at least one compliant region adapted and configured to be placed over a joint of a subject and at least two flexible but less compliant regions coupled to opposite ends of the compliant region. The device provides a wearable robotic device including a wearable and at least one actuator adapted and configured to move the flexible but less compliant regions relative to each other.
    Type: Grant
    Filed: November 13, 2018
    Date of Patent: November 5, 2019
    Assignee: Drexel University
    Inventors: Andrew Cohen, Genevieve Dion, Mark Winter, Eric Wait, Michael Koerner
  • Patent number: 10460881
    Abstract: A method of making a supercapacitor from waste tires, includes the steps of providing rubber pieces and contacting the rubber pieces with a sulfonation bath to produce sulfonated rubber; pyrolyzing the sulfonated rubber to produce a tire-derived carbon composite comprising carbon black embedded in rubber-derived carbon matrix comprising graphitized interface portions; activating the tire-derived carbon composite by contacting the tire-derived carbon composite with a specific surface area-increasing composition to increase the specific surface area of the carbon composite to provide an activated tire-derived carbon composite; and, mixing the activated tire-derived carbon composite with a monomer and polymerizing the monomer to produce a redox-active polymer coated, activated tire-derived carbon composite. The redox-active polymer coated, activated tire-derived carbon composite can be formed into a film. An electrode and a supercapacitor are also disclosed.
    Type: Grant
    Filed: March 16, 2018
    Date of Patent: October 29, 2019
    Assignees: UT-Battelle, LLC, Drexel University
    Inventors: Amit K Naskar, Mariappan Parans Paranthaman, Muhammad Boota, Yury Gogotsi