Abstract: The constrained watershed boundary (CWB), defined as a polygon containing all the flow direction grid cells with a surface flow distance less than a user prescribed threshold uses an algorithm that builds upon the HSM algorithm proposed and augments the data structure with a flow distance grid calculated directly from the original flow direction grid.

Abstract: The increasing power density and, therefore, current consumption of high performance integrated circuits (ICs) results in increased challenges in the design of a reliable and efficient on-chip power delivery network. In particular, meeting the stringent on-chip impedance of the IC requires circuit and system techniques to mitigate high frequency noise that results due to resonance between the package inductance and the onchip capacitance. In this paper, a novel circuit technique is proposed to suppress high frequency noise through the use of a hyperabrupt junction tuning varactor diode as a decoupling capacitor for noise critical functional blocks. With the proposed circuit technique, the voltage droops and overshoots on the onchip power distribution network are suppressed by up to 60% as compared to MIM or deep trench decoupling capacitors of the same capacitance.

Abstract: Organometallic compounds comprising a chloroquinoline moiety for use in the prophylaxis and treatment of malaria. The compounds can be manganese or rhenium complexes of a ligand comprising a chloroquinoline moiety.

Abstract: Presenting a visualization of antenna radiation patterns may include sending a request to a server for up-to-date information regarding an antenna mode; receiving the request at the server and reading a register value for the antenna mode; responding, by the server, with updated antenna mode information; and overlaying antenna radiation patterns on an image based on the mode information.

Abstract: Disclosed herein are atmospheric pressure pin-to-hole pulsed spark discharge devices and methods for creating plasma. The devices include a conduit for fluidically communicating a gas, a plasma, or both, therethrough, portion of the conduit capable of being connected to a gas supply, and a second portion of the conduit capable of emitting a plasma; a positive electrode comprising a sharp tip; and a ground plate electrode. Disclosed are methods for treating a skin ulcer using non-thermal plasma include flowing a gas through a cold spark discharge zone simultaneously with the creation of a pulsed spark discharge to give rise to a non-thermal plasma emitted from a conduit, the non-thermal plasma comprising NO; and contacting a skin ulcer with said non-thermal plasma for sufficient time and intensity to give rise to treatment of the skin ulcer.

Abstract: A system, device and methods for quantitatively monitoring and evaluating changes in water and hemoglobin content in the brain in a non-invasive manner are provided. The system may be used for real-time detection and monitoring of brain edema and/or for an assessment of cerebral autoregulation.

Abstract: A key-based interleaver for enhancement the security of wireless communication includes a physical layer communication channel key to provide security even when the software encryption key is compromised. A method of creating a secure communication link using a physical layer interleaving system includes implementing a key policy implementation that utilizes temporal dependency and interleaving bits using a flexible inter and intra-block data interleaver.

Abstract: A system for delivering physical therapy to a user includes an active video gaming system that has a motion detector capable of detecting the physical motions of a user. The system includes parameters related to movement restrictions that a user may have and the system creates a gaming environment based on the parameters.

Abstract: A physical layer based technique secures wireless communication between a transmitter and receiver. The technique involves obfuscating the preamble data of the baseband signal through unique keys that are generated at the transmitter and the receiver based on channel characteristics known only to them.

Abstract: An inventive approach is disclosed to integrate Digital Image Correlation (DIC) with the Acoustic Emission method that may be used for structural health monitoring and assessment of critical structural components in civil, mechanical, and aerospace industries. The inventive approach relies on passively recording acoustic emission across the specimen being tested and activating the DIC cameras automatically to measure deformation on the specimen's surface. The resulting acousto-optic system can be used to determine damage initiation, progressive damage development, identify critical regions and make lifetime predictions of the tested specimen.

Abstract: An implantable medical device having a sheath formed of a polymer material, wherein the sheath forms a reservoir attached to or around the implantable medical device, and wherein the reservoir is sealed with a biocompatible pressure responsive coating; wherein the biocompatible coating is stable for at least 7-day post implantation into a body, and can be mechanically ruptured by application of an exterior pressure generating force.

Abstract: A wearable device includes: at least one compliant region adapted and configured to be placed over a joint of a subject and at least two flexible but less compliant regions coupled to opposite ends of the compliant region. The device provides a wearable robotic device including a wearable and at least one actuator adapted and configured to move the flexible but less compliant regions relative to each other.

Abstract: A sensing method is based on using a special fiberoptic probe for detection of acoustic/ultrasound pressure in an immersion medium. The developed system is highly sensitive in detecting ultrasound waves up to 100 MHz, for imaging of micro structures and more. For applications up to 100 MHz, without spatial averaging corrections, the probe tip is modified by reducing the fiber diameter to 7 um or less. Also, to maximize acousto-optic interaction, the probe tip, not just its end face, may be coated with a thin layer of metallic material. This thin film coating satisfies partial transparency of the metallic coating. The coating thickness may range from 2 nm to 10 nm or others depending on the type of the coating material. The probe detects the pressure of acoustic and/or ultrasound waves propagating within an immersion medium, whenever the probe tip is immersed inside the medium, and having a reasonable immersion contact surface.

Abstract: One embodiment is a biochip having an array of biosensors for quantitative determination of protein-protein and/or antibody-antigen interactions. The array comprises at least two biosensors formed on a substrate. The biosensors can be used to detect either the same or different analytes. The biosensors may be acoustical transducers operated in the thickness shear mode of vibration, wherein the density, viscosity, and elasticity at the sensor interface can be ascertained. Additionally, a series of fluidic channels are etched to the same depth as the biosensors. The fluidic channels serve to efficiently deliver the sample to the biosensors. One or more biochips can be housed within an enclosure.

Abstract: A method of making a supercapacitor from waste tires, includes the steps of providing rubber pieces and contacting the rubber pieces with a sulfonation bath to produce sulfonated rubber; pyrolyzing the sulfonated rubber to produce a tire-derived carbon composite comprising carbon black embedded in rubber-derived carbon matrix comprising graphitized interface portions; activating the tire-derived carbon composite by contacting the tire-derived carbon composite with a specific surface area-increasing composition to increase the specific surface area of the carbon composite to provide an activated tire-derived carbon composite; and, mixing the activated tire-derived carbon composite with a monomer and polymerizing the monomer to produce a redox-active polymer coated, activated tire-derived carbon composite. The redox-active polymer coated, activated tire-derived carbon composite can be formed into a film. An electrode and a supercapacitor are also disclosed.

Abstract: The present invention includes novel RAD52 inhibitors for preventing or treating cancers in a subject in need thereof. The present invention further includes a method of preventing or treating cancers in a subject in need thereof, the method comprising administering to the subject an effective amount of a compound of the invention. In certain embodiments, the subject is further administered at least one additional therapeutic agent.

Abstract: Grafted triglycerides comprising a triglyceride grafted with a fatty acid residue containing 4 to 30 carbon atoms are reacted with an epoxide resin and an amine curing agent to yield an epoxy thermoset. The grafted triglyceride is prepared by reaction of an epoxidized triglyceride with a fatty acid. By varying the length of the fatty residue, the number of fatty residues per triglyceride, the identity of the epoxy resin and the amine curing agent, it is possible to prepare epoxy thermosets that exhibit superior physical properties compared to the properties of epoxy thermosets prepared without the grafted triglyceride, or as compared to epoxy thermosets wherein the epoxidized triglyceride is used in place of the grafted triglyceride.

Abstract: The present invention provides compounds useful for treating or preventing an IL-1R-mediated disease or disorder. In certain embodiments, the disease or disorder comprises scleroderma.

Abstract: The present invention includes compositions that are useful in preventing or treating metastasis in a subject diagnosed with cancer. The present invention also includes methods of preventing or treating metastasis in a subject diagnosed with cancer, wherein the method comprises administering to the subject in need thereof an effective amount of a pharmaceutical formulation comprising at least one pharmaceutically acceptable carrier and at least one CX3CR1 or fractalkine antagonist.

Abstract: A reactive jamming software defined radio (SDR) apparatus to target Frequency Hopping Spread-Spectrum (FHSS) signals includes a peripheral module for SDR processing; a reactive jamming hardware IP core that implements time-sensitive operations on a field programmable gate array (FGPA); and a host computer that implements non-time-critical operations, such as jammer configuration, logging, and strategy composition.