Abstract: Pharmaceutical compositions of the invention comprise triazolopyrimidines useful for the treatment of hepatitis virus in a patient.

Abstract: Disclosed herein are nanoscale devices comprising one or more ferroelectric nanoshells characterized as having an extreme curvature in at least one spatial dimension. Also disclosed are ferroelectric field effect transistors and metal ferroelectric metal capacitors comprising one or more ferroelectric nanoshells. Methods for controlling spontaneous ferroelectric polarization in nanoshell devices are also disclosed.

Abstract: A flow chamber and method for detecting the presence of one more cell produced analytes under flow conditions. The flow chamber includes two compartments separated by a permeable membrane on which a plurality of cells may be positioned. The permeable membrane shields one or more analyte sensors positioned one compartment from the convective transport forces of a fluid flow within the other compartment to allow reliable and accurate detection of cell-produced analytes and determination of the concentration of cell-produced analytes.

Abstract: A real-time capable, protocol-aware, reactive jammer using GNU Radio and the USRP N210 software-defined radio (SDR) platform detects in-flight packets of known wireless standards and reacts to jam them—within 80 ns of detecting the signal. A reactive jamming device is achieved using low-cost, readily available hardware. The real-time reactive jamming device includes a real-time signal detector that detects an event in received packets in the wireless network, a reactive jamming device that sends a triggering signal when the event is detected, and a jamming generator responsive to the triggering signal to generate a jamming signal that has a user-defined delay so as to enable jamming of specific locations in received packets in the wireless network. The effects of three types of jamming on WiFi (802.11g) and mobile WiMAX (802.16e) networks are demonstrated and jamming performances are quantified by measuring the network throughput using the iperf software tool.

Abstract: A piezoelectric plate sensor comprising a piezoelectric layer; two electrodes; and an insulation layer. The insulation layer is produced by soaking the piezoelectric layer and two electrodes in a mercaptopropyltrimethoxysilane solution with an amount of water from 0.1 v/v. % to about 1 v/v % and at pH from about 8 to about 150 for a period from about 8 to about 15 hours, and the mercaptopropyltrimethoxysilane solution has a concentration of mercaptopropyltrimethoxysilane from about 0.01 v/v % to about 0.5 v/v %. A method of detecting a biomolecule in a sample using the piezoelectric plate sensor in particular, that of detecting a genetic marker with PCR sensitivity and specificity without the need of DNA isolation or amplification is also provided. The piezoelectric plate sensor may be used to diagnose various diseases including breast cancer, myocardial infarction, diarrhea, Clostridium difficile infection, and hepatitis B infection.

Abstract: Disclosed herein are atmospheric pressure pin-to-hole pulsed spark discharge devices and methods for creating plasma. The devices include a conduit for fluidically communicating a gas, a plasma, or both, therethrough, portion of the conduit capable of being connected to a gas supply, and a second portion of the conduit capable of emitting a plasma; a positive electrode comprising a sharp tip; and a ground plate electrode. Disclosed are methods for treating a skin ulcer using non-thermal plasma include flowing a gas through a cold spark discharge zone simultaneously with the creation of a pulsed spark discharge to give rise to a non-thermal plasma emitted from a conduit, the non-thermal plasma comprising NO; and contacting a skin ulcer with said non-thermal plasma for sufficient time and intensity to give rise to treatment of the skin ulcer.

Abstract: An apparatus and method for determining the depth of an object below a surface or the thickness of the dermis. The apparatus and method use a plurality of piezoelectric fingers having probes with differently sized contact areas. A plurality of measurements is taken using each of the probes with differently sized contact areas in order to determine the depth of an object below a surface or the thickness of the dermis.

Abstract: The invention is directed to a cervical spine protection apparatus one or more composite bands attached to provide restraint of one or more motions of the cervical spine of a wearer. The apparatus is designed to protect a wearer from incurring cervical spinal injuries, and/or to reduce the severity of cervical spine injuries without substantially compromising the normal functional range of motion of the wearer's cervical spine.

Abstract: The inventions described herein are directed to technologies for reforming high temperature feedstreams into clean synthesis gas, more particularly, reactor configurations and methods for reforming pyrogas using non-thermal plasmas. One embodiment provides a plasma reactor comprising: (a) a substantially cylindrical reactor wall having a first closed proximal end and a second open distal end, wherein at least a portion of said wall is configured to comprise a first electrode; and (b) a second elongated electrode electrically separated from the first electrode by an electrical insulator, said electric insulator forming either part or all of the first closed end of the reactor or positioned proximate thereto; and configured to be capable of generating and maintaining a glid ing arc plasma discharge within a zone in said reactor.

Abstract: A method for enhancing the detection sensitivity of a piezoelectric microcantilever sensor. The method may involve providing a piezoelectric microcantilever and inducing a change in the Young's modulus during detection of a species of interest. The change in the Young's modulus may be induced or enhanced by the application of a DC bias electric field to the piezoelectric layer that enhances non-180° polarization domain switching of the piezoelectric layer. The change in the Young's modulus may also result from binding of the species of interest to the piezoelectric microcantilever sensor or a combination of binding and application of a DC bias electric field. Significantly enhanced detection sensitivity results from the changed Young's modulus of the piezoelectric layer.

Abstract: Disclosed herein are ferroelectric perovskites characterized as having a band gap, Egap, of less than 2.5 eV. Also disclosed are compounds comprising a solid solution of KNbO3 and BaNi1/2Nb1/2O3-delta, wherein delta is in the range of from 0 to about 1. The specification also discloses photovoltaic devices comprising one or more solar absorbing layers, wherein at least one of the solar absorbing layers comprises a semiconducting ferroelectric layer. Finally, this patent application provides solar cell, comprising: a heterojunction of n- and p-type semiconductors characterized as comprising an interface layer disposed between the n- and p-type semiconductors, the interface layer comprising a semiconducting ferroelectric absorber layer capable of enhancing light absorption and carrier separation.

Abstract: A dynamic rotary traveling wave oscillator circuit includes plurality of multi-output spot-advancing blocks (MOSABs) forming a main-loop and a plurality of multi-input spot-advancing blocks (MISABs) forming a sub-loop. Depending on a desired division ratio, a connection connects blocks on the MOSABs and MISABs to create the desired division ratio.

Abstract: A single sensing probe comprising multiple, spatially separate, sensing sites is utilized to sense neural activity. The sensing probe includes multiple conductors each with multiple sensing sites in a fixed geometric arrangement. The sensing probe is configured to comprise multiple combined sensing sites in polytrode configuration. By appropriately combining the wire groupings at each combined sensing site, activity sensed from a single wire with multiple sensing sites, can be coupled with other wires to unmix signals from the spatially separate sites and leverage the power of combinatorics to maximize total recording bandwidth and single neuron/unit yield per wire and per probe.

Abstract: Cooling systems and methods for cooling in a power plant using a phase change material. In one embodiment, a phase change material container includes at least one phase change material which may be in the form of a slurry; and at least one conduit for transporting the fluid through the phase change material when located in the phase change material container. The system may also comprise an air flow chamber; and a phase change material flow system including a pump for pumping phase change material from an outlet of phase change material container, to at least one phase change material spray nozzle. The phase change material flow system is configured to ensure that solidified phase change material is returned to the phase change material container.

Abstract: The present invention provides a method of producing fatty acid alkyl esters from a lipid, comprising steps of introducing a gas comprising vapor of an alcohol selected from methanol, ethanol, 1-propanol, iso-propanol and butanols, into the lipid in a form of bubbles to enable the bubbles to pass through the lipid and be discharged from the lipid. The product may then be subjected to a transesterification process catalyzed by a base catalyst. The present invention is robust with low quality feedstocks thus significantly reduce production cost for biodiesel.

Abstract: A soft magnetic composite comprising an iron or iron alloy ferromagnetic material coated with an oxide material. An interface between the ferromagnetic material and the layer of oxide contains antiphase domain boundaries. Two processes for producing a soft magnetic composite are also provided. One process includes depositing an oxide layer onto an iron or iron alloy ferromagnetic material by molecular beam epitaxy at a partial oxygen pressure of from 1×10?5 Torr to 1×10?7 Torr to form a coated composite. The other process includes milling an iron or iron alloy ferromagnetic material powder and an oxide powder by high-energy milling to form a mixture; compacting the mixture and curing in an inert gas atmosphere at a temperature from 500° C. to 1200° C. to form a soft magnetic composite.

Abstract: A novel quantum dot containing two different metals at non-toxic levels which is capable of narrow bandwidth near infrared emissions at wavelengths of 600-1100 nm. The quantum dot is fabricated via an aqueous method which forms a structure having an inner region of one composition and an outer region of a different composition, wherein the inner region contains at least a first metal and the outer region contains at least a second metal. The quantum dots may be enabled for bioconjugation and may be used in a method for tissue imaging and analyte detection.

Abstract: A modular lift system that can be mounted on a stairway is disclosed. The system includes forks located on a first floor onto which the user rolls their wheelchair. The forks are motor operated to traverse a toothed track between the first floor and a second floor with the wheelchair and the user riding the forks. When the forks reach the second floor, the user rolls the wheelchair off the forks.

Abstract: Multi-frequency Diffuse Photon Density Wave (DPDW) methodology at near infrared wavelengths is used to non-invasively measure the optical absorption and reduced scattering coefficients of tissue at depths of several millimeters to quantify the depth and degree of tissue damage. A digitally-controlled stepper motor and variable RF generator enable the user to select the distance between the light source and detector and the modulation frequency through software. This allows for the collection of virtually unlimited number of data points, enabling precise selection of the volume and depth of tissue that will be characterized.

Abstract: An aqueous approach to synthesize capped SnS quantum dots (QDs) followed by optional capping molecule extension by attaching one or more extending molecules to the capping molecule via peptide bond formation at elevated temperature. The capped SnS QDs may have a capping molecule:Sn:S molar ratio of 16:3:1 to 16:12:1. A suspension of SnS QDs was heat-treated at 200° C. for 0.5-4 hrs. The obtained SnS QDs showed an NIR emission peak at 820-835 nm with an excitation wavelength at 690 nm. The as synthesized SnS QDs were found to have high positive zeta potential of ˜30 mV and thus were toxic to cells. By neutralizing the SnS QDs the cytotoxicity was reduced to an accepted level. The heat-treatment step can be obviated by adding a glycerol solution containing S2? anions and capping molecule to a glycerol solution of Sn2+ ions.