Abstract: A key-based interleaver for enhancement the security of wireless communication includes a physical layer communication channel key to provide security even when the software encryption key is compromised. A method of creating a secure communication link using a physical layer interleaving system includes implementing a key policy implementation that utilizes temporal dependency and interleaving bits using a flexible inter and intra-block data interleaver.
Type:
Grant
Filed:
June 5, 2019
Date of Patent:
December 27, 2022
Assignee:
Drexel University
Inventors:
Kapil R. Dandekar, James J. Chacko, Kyle Joseph Juretus, Marko Jacovic, Cem Sahin, Nagarajan Kandasamy, Ioannis Savidis
Abstract: This invention relates to a method for synthesizing polyoxymethylene on a substrate. The method includes depositing monomer capable of forming polyoxymethylene by an initiated polymerization reaction and an initiator, via initiated chemical vapor deposition (iCVD) onto a surface of a substrate in an initiated chemical vapor deposition reactor.
Abstract: A multi-site probe for interfacing with the central nervous system includes one more structures disposed perpendicularly on a backing layer, where each structure includes a braided sleeve over a flexible or rigid core, and a delivery-vehicle. The structures may include optrodes and electrodes. The location of the probe may be determined through the application of combinatorics.
Abstract: An incremental author disambiguation framework may create new clusters to accommodate new data based on the existing cluster results and newly added data. The proposed system may provide frequent update of taxonomic classification, name disambiguation and many other applications because it takes less time to generate new results. In addition, the proposed methods may reduce the time needed for updating the model and help improve the performance with the limited computational resource.
Abstract: The present invention is directed to methods of making a nanofiber-nanoparticle network to be used as electrodes of fuel cells. The method comprises electrospinning a polymer-containing material on a substrate to form nanofibers and electrospraying a catalyst-containing material on the nanofibers on the same substrate. The nanofiber-nanoparticle network made by the methods is suitable for use as electrodes in fuel cells.
Type:
Grant
Filed:
May 19, 2020
Date of Patent:
October 11, 2022
Assignee:
Drexel University
Inventors:
Yossef A. Elabd, Francis W. Richey, Kevin H. Wujcik
Abstract: The present disclosure is directed to electroacoustical devices comprising patterned MXene compositions on biaxially oriented polymer substrates and methods of making and using the same.
Type:
Grant
Filed:
June 4, 2019
Date of Patent:
October 11, 2022
Assignee:
Drexel University
Inventors:
Devon J. Spinelli, Thomas Heng, Asia Sarycheva, Pavel S. Lelyukh, Yury Gogotsi
Abstract: A system, device and methods for quantitatively monitoring and evaluating changes in water and hemoglobin content in the brain in a non-invasive manner are provided. The system may be used for real-time detection and monitoring of brain edema and/or for an assessment of cerebral autoregulation.
Type:
Grant
Filed:
October 23, 2019
Date of Patent:
October 4, 2022
Assignee:
Drexel University
Inventors:
Meltem Izzetoglu, Juan Du, Baruch Ben Dor, Shadi Malaeb
Abstract: The present disclosure is directed to antennas for transmitting and/or receiving electrical signals comprising a MXene composition, devices comprising these antennas, and methods of transmitting and receiving signals using these antennas.
Abstract: The present invention relates to a method for assembling particles having a long axis, a short axis and an average aspect ratio of 10-10,000. The method includes agitating a combination of a first solution, a second solution and the particles in any order to form a mixture wherein one of the first solution and the second solution is in the form of droplets dispersed in the other of the first solution and the second solution and the long axis of the particles is longer than a diameter of the droplets in the mixture, and continuing the agitation until the particles assemble into aggregates of particles with at least 30% of the particles aligned in parallel along the long axis. Aggregate or aggregate composites form by the method are also described.
Type:
Application
Filed:
August 28, 2020
Publication date:
September 22, 2022
Applicant:
Drexel University
Inventors:
Joy Rene BAXTER, Nicolas Javier ALVAREZ, Giuseppe Rafaello PALMESE
Abstract: The increasing power density and, therefore, current consumption of high performance integrated circuits (ICs) results in increased challenges in the design of a reliable and efficient on-chip power delivery network. In particular, meeting the stringent on-chip impedance of the IC requires circuit and system techniques to mitigate high frequency noise that results due to resonance between the package inductance and the onchip capacitance. In this paper, a novel circuit technique is proposed to suppress high frequency noise through the use of a hyperabrupt junction tuning varactor diode as a decoupling capacitor for noise critical functional blocks. With the proposed circuit technique, the voltage droops and overshoots on the onchip power distribution network are suppressed by up to 60% as compared to MIM or deep trench decoupling capacitors of the same capacitance.
Abstract: A real-time workload scheduling heuristic assigns tasks to the cores such that the total load current consumption of the cores is always less than the total current capability of the under-provisioned on-chip voltage regulators. In addition, the energy-efficient scheduling of the tasks on to the cores ensures that the reconfiguration of the power delivery network is minimized. The heuristic includes DVFS management based on the unique constraints of the under provisioned voltage regulators.
Type:
Grant
Filed:
May 1, 2018
Date of Patent:
September 6, 2022
Assignee:
Drexel University
Inventors:
Ioannis Savidis, Divya Pathak, Houman Homayoun
Abstract: The present invention is an apparatus and method of using the apparatus for separating individual particles from a collection of clumps (or bundles or aggregates) of particles. The apparatus has n number of separation columns, wherein each separation column is connected at an upper portion thereof to at least one fluid connection, and a particle collector. A pressurized fluid flows through the apparatus and 1) suspends a portion of the clumps within the separation column and/or the at least one fluid connection thereby separating at least some clumps into smaller clumps and/or individual particles; and 2) conveys a portion of the clumps and/or individual particles to the next separation column in the series of separation columns, or, in the case of the nth separation column conveys individual particles to the particle collector.
Type:
Application
Filed:
July 31, 2020
Publication date:
September 1, 2022
Applicant:
Drexel University
Inventors:
Maria Mercedes DIAZ ACEVEDO, Simge UZUN, Nicolas Javier ALVAREZ, Giuseppe Rafaello PALMESE
Abstract: Groups of architecturally connected files may incur and accumulate high maintenance costs as architectural debts. To quantify such debts, architectural debt, which is a term used herein, may be identified, quantified, measured, and modeled. A history coupling probability matrix for this purpose may search for architecture debts through the lens of 4 patterns of prototypical architectural flaws shown to correlate with reduced software quality. Further, a new architecture maintainability metric—Decoupling Level (DL)—measures how well the software can be decoupled into small and independently replaceable modules. The DL metric opens the possibility of quantitatively comparing maintainability between different projects, as well as monitoring architecture decay throughout software evolution.
Type:
Grant
Filed:
December 19, 2016
Date of Patent:
August 23, 2022
Assignee:
Drexel University
Inventors:
Yuanfang Cai, Lu Xiao, Frederick Kazman, Ran Mo
Abstract: This invention outlines a method for synthesizing a blended resin system in a one pot reaction that may utilize, for example, bio-based anhydrosugars such as isosorbide as a principle component to produce isosorbide dimethacrylate and other monomeric materials for thermosetting applications. This invention establishes a one-pot procedure for reacting a hydroxy group containing compound with methacrylic anhydride in the first step and using the by-product methacrylic acid to react with glycidyl ethers to form additional methacrylate compounds in the second step. This methodology can be formulated to produce a wide array of resin systems that have controlled ratios of hydroxy group containing compound/cross-linker/reactive diluent. Additionally, the novel resin systems may be partially to fully bio-based, promoting global sustainability and reducing costs, and when free radically polymerized have properties that meet or exceed their petroleum derived counterparts.
Type:
Application
Filed:
November 18, 2021
Publication date:
August 18, 2022
Applicants:
DREXEL UNIVERSITY, The Government of the United States of America as Represented by the Secretary of the Army
Inventors:
Joshua Matthew Sadler, John Joseph La Scala, Giuseppe R. Palmese
Abstract: Applications of dielectric barrier discharge (DBD) based atmospheric pressure plasma jets are often limited by the relatively small area of treatment due to their 1D configuration. This system generates 2D plasma jets permitting fast treatment of larger targets. DBD evolution starts with formation of transient anode glow, and continues with development of cathode-directed streamers. The anode glow can propagate as an ionization wave along the dielectric surface through and outside of the discharge gap. Plasma propagation is not limited to 1D geometry such as tubes, and can be organized in a form of a rectangular plasma jet, or other 2D or 3D shapes. Also described are a method for generating 2D plasma jets and use of the 2D plasma jets for cancer therapy.
Type:
Application
Filed:
January 3, 2022
Publication date:
August 11, 2022
Applicants:
Drexel University, Thomas Jefferson University
Inventors:
Danil V. DOBRYNIN, Alexander FRIDMAN, Abraham LIN, Vandana MILLER, Adam Snook
Abstract: The present invention provides methods for preparing acoustically-sensitive microbubbles. The method includes the steps of: i) preparing a first surfactant solution comprising a first micelle-forming surfactant at a concentration above the critical micelle concentration (CMC); ii) adding one or more pharmaceutical compounds in a solvent to the first surfactant solution, thereby loading the micelles with the one or more pharmaceutical compounds; iii) preparing a second surfactant solution comprising a second surfactant, wherein the second surfactant comprises one or more matrix forming surfactants; iv) adding heat to the second surfactant solution to melt the surfactant and allowing the mixture to cool under rapid stirring; v) combining the second surfactant solution with the loaded micelles; vi) purging the surfactant mixture with a purging gas; vii) agitating the purged mixture under a constant stream of the purging gas; and, viii) separating the formed microbubbles by size.
Type:
Application
Filed:
May 29, 2020
Publication date:
August 11, 2022
Applicants:
Drexel University, Thomas Jefferson University
Inventors:
Margaret A. Wheatley, John Robert Eisenbrey, Brian E. Oeffinger, Purva Vaidya
Abstract: Provided are methods, assays, and kits for detecting hepatocellular carcinoma, as well as methods for stratifying subjects among higher and lower risk categories for having hepatocellular carcinoma, and methods of treating and managing treatment of subjects that are suspected or at risk of having hepatocellular carcinoma. Although previous work has attempted to address the need for a highly sensitive, early predictor of hepatocellular carcinoma by assessment of one or more biological factors, none have approached the degree of sensitivity that is required for clinically relevant determination of whether a subject, especially a non-symptomatic subject, has that condition. The present inventors have discovered that certain combinations of factors fulfill this need by conferring a high level of accuracy that was not previously attainable.
Type:
Grant
Filed:
February 16, 2017
Date of Patent:
August 9, 2022
Assignee:
Drexel University
Inventors:
Timothy M. Block, Mengjun Wang, Anand Mehta, Mary Ann Comunale
Abstract: The present disclosure is directed to compositions comprising at least one layer having first and second surfaces, each layer comprising: a substantially two-dimensional array of crystal cells, each crystal cell having an empirical formula of M?2M?nXn+1, such that each X is positioned within an octahedral array of M? and M?; wherein M? and M? each comprise different Group 11113, WE, VB, or VIB metals; each X is C, N, or a combination thereof; n=1 or 2; and wherein the M? atoms are substantially present as two-dimensional outer arrays of atoms within the two-dimensional array of crystal cells; the M? atoms are substantially present as two-dimensional inner arrays of atoms within the two-dimensional array of crystal cells; and the two dimensional inner arrays of M? atoms are sandwiched between the two-dimensional outer arrays of M? atoms within the two-dimensional army of crystal cells.
Type:
Grant
Filed:
June 5, 2020
Date of Patent:
August 9, 2022
Assignee:
Drexel University
Inventors:
Michel W Barsoum, Babak Anasori, Yury Gogotsi
Abstract: One aspect of the invention provides a method for freeze-drying surfactant-stabilized microbubbles. The method includes: preparing vials comprising a mixture comprising microbubbles; partially submerging the vials in a chilled water bath, wherein the water bath has a sub-freezing temperature; placing the vials on a cooled shelf of a lyophilizer; freeze-drying the vials in the lyophilizer; and capping the freeze-dried vials. Another aspect of the invention provides a method for annealing surfactant-stabilized microbubbles. The method includes: preparing vials comprising a mixture comprising microbubbles; passing the vials in and out of liquid nitrogen (LN2) until the mixture is frozen; holding the vials at ?20° C.; placing the vials on a cooled shelf of a lyophilizer; freeze-drying the vials in the lyophilizer; and capping the freeze-dried vials.
Type:
Grant
Filed:
March 13, 2020
Date of Patent:
July 19, 2022
Assignees:
Thomas Jefferson University, Drexel University
Inventors:
Brian Edward Oeffinger, Margaret A. Wheatley, Rawan Shraim, Purva Vaidya, John Robert Eisenbrey
Abstract: The present invention includes a construct that comprises at least one microbubble encapsulated within the aqueous core of a microcapsule. The present invention also includes a pharmaceutical composition comprising a construct comprising at least one microbubble encapsulated within the aqueous core of a microcapsule. The present invention further includes a method of imaging a tissue or organ in a subject, a method of delivering a therapeutic cargo to a tissue or organ in a subject, and a method of treating a disease or disorder in a subject.