Patents Assigned to Drexel University
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Patent number: 11282414Abstract: There are several approaches to encrypting circuits: combination logic encryption, encrypted gate topologies, transmission gate topologies, and key expansion of gate topologies. One of the approaches provides a circuit having a gate topology comprising a logic gate with integrated key transistors, where the key transistors comprise at least a PMOS stack and an NMOS stack. The PMOS stack comprises a first PMOS switch and a second PMOS switch, where the first and the second PMOS switches have sources to a voltage source and drains that serve as a source to a third PMOS switch. The NMOS stack comprises a first NMOS switch and a second NMOS switch, where the first and the second NMOS switches have sources to ground and drains that serve as a source to a third NMOS switch. Each of the above approaches may encrypt a circuit with certain advantages in delay and power consumption.Type: GrantFiled: October 24, 2016Date of Patent: March 22, 2022Assignee: Drexel UniversityInventors: Ioannis Savidis, Kyle Juretus
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Patent number: 11278862Abstract: The present disclosure is directed to methods for scrubbing low levels of urea from aqueous solutions such as a dialysate from dialysis, and including blood and blood products, and devices capable of employing these methods.Type: GrantFiled: July 12, 2018Date of Patent: March 22, 2022Assignees: Drexel University, University of BrightonInventors: Yury Gogotsi, Sergey Mikhalovsky, Susan R. Sandeman, Babak Anasori, Fayan Meng
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Patent number: 11266752Abstract: The present disclosure provides imaging agents that are useful for the detection and evaluation of heart conditions, such as myocardial infarction. Upon activation, the imaging agents of the present disclosure may be detected using an ultrasound imaging device.Type: GrantFiled: August 16, 2021Date of Patent: March 8, 2022Assignee: Drexel UniversityInventors: Steven Wrenn, Brett Angel, Andrew Kohut, Aaron Fafarman, Michael Cimorelli
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Patent number: 11267817Abstract: The disclosure provides compounds of formula (I) having the structure: Compounds of formula (I) are fractalkine receptor agonists and useful in treating, preventing or minimizing metastasis in a subject diagnosed with cancer. The compounds of the invention are further useful in treating central nervous system diseases (such as, but not limited to, HIV Associated Neurocognitive Disorders (HAND), and/or Alzheimer's disease), pain, inflammation (such as, but not limited to, arthritis), cardiovascular disease (such as, but not limited to, undesired vascular smooth muscle proliferation, atherosclerosis, coronary vascular endothelial dysfunction, and/or coronary artery disease), and/or multiple sclerosis.Type: GrantFiled: May 1, 2018Date of Patent: March 8, 2022Assignee: Drexel UniversityInventors: Joseph M. Salvino, Xin Feng, Alessandro Fatatis, Fei Shen, Olimpia Meucci
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Patent number: 11266751Abstract: The present disclosure provides imaging agents that are useful for the detection and evaluation of heart conditions, such as myocardial infarction. Upon activation, the imaging agents of the present disclosure may be detected using an ultrasound imaging device.Type: GrantFiled: March 17, 2021Date of Patent: March 8, 2022Assignee: Drexel UniversityInventors: Steven Wrenn, Brett Angel, Andrew Kohut, Aaron Fafarman, Michael Cimorelli
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Patent number: 11269425Abstract: A planar (two-dimensional, XY location) touch sensor may include a knitted structure and supplementary method of sensing detects human touch on a fabric surface. This sensor may be fully knitted and detect the continuous planar location and contact force of human touch along the surface of the structure. The fabric may conform to any arbitrary surface and may be a rectangle for touch pad applications. This sensor may be used for applications that include robotics and human-machine interaction, smart garments and wearables, as well as medical textiles and flexible embedded sensors. This touch sensor may require as few as only two electrode connections from the fabric to sense both planar touch and pressure, which allows it to work in areas with limited space that allow for limited complexity for wiring.Type: GrantFiled: October 30, 2020Date of Patent: March 8, 2022Assignee: Drexel UniversityInventors: Richard James Vallett, Ryan David Young, Robert Wallace Lehrich, Christina Dickinson Kara, Genevieve Dion, Youngmoo Edmund Kim
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Patent number: 11266612Abstract: The present invention provides a method of inhibiting, suppressing or preventing levodopa-induced dyskinesia in a patient suffering from Parkinson's Disease, comprising the step of administering to the patient a pharmaceutical composition comprising at least one compound of the invention. The present invention further provides a method of inhibiting, suppressing or preventing Parkinson's Disease in a patient, comprising the step of administering to the patient a pharmaceutical composition comprising at least one compound of the invention.Type: GrantFiled: January 24, 2020Date of Patent: March 8, 2022Assignees: Drexel University, Rutgers, The State University of New JerseyInventors: Sandhya Kortagere, Eldo V. Kuzhikandahil
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Patent number: 11270031Abstract: The transition to a horizontal integrated circuit (IC) design flow has raised concerns regarding the security and protection of IC intellectual property (IP). Obfuscation of an IC has been explored as a potential methodology to protect IP in both the digital and analog domains in isolation. However, novel methods are required for analog mixed-signal circuits that both enhance the current disjoint implementations of analog and digital security measures and prevent an independent adversarial attack of each domain. A methodology generates functional and behavioral dependencies between the analog and digital domains that results in an increase in the adversarial key search space. The dependencies between the analog and digital keys result in a 3× increase in the number of iterations required to complete the SAT attack.Type: GrantFiled: April 29, 2020Date of Patent: March 8, 2022Assignee: Drexel UniversityInventors: Ioannis Savidis, Vaibhav Venugopal Rao, Kyle Joseph Juretus
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Patent number: 11243200Abstract: A piezoelectric plate sensor comprising a piezoelectric layer; two electrodes; and an insulation layer. The insulation layer is produced by soaking the piezoelectric layer and two electrodes in a mercaptopropyltrimethoxysilane solution with an amount of water from 0.1 v/v. % to about 1 v/v % and at pH from about 8 to about 150 for a period from about 8 to about 15 hours, and the mercaptopropyltrimethoxysilane solution has a concentration of mercaptopropyltrimethoxysilane from about 0.01 v/v % to about 0.5 v/v %. A method of detecting a biomolecule in a sample using the piezoelectric plate sensor in particular, that of detecting a genetic marker with PCR sensitivity and specificity without the need of DNA isolation or amplification is also provided. The piezoelectric plate sensor may be used to diagnose various diseases including breast cancer, myocardial infarction, diarrhea, Clostridium difficile infection, and hepatitis B infection.Type: GrantFiled: December 11, 2018Date of Patent: February 8, 2022Assignee: Drexel UniversityInventors: Wan Y. Shih, Wei Wu, Wei-Heng Shih, Mehmet Cagri Soylu, Haitao Guo, Suresh G. Joshi, Ceyhun Ekrim Kirimli, Ying-Hsiu Su
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Patent number: 11243559Abstract: Modern integrated circuits have an increasing need for various levels of both supply voltage (V) and operating frequency (f) available at fine spatial and temporal granularity. This work introduces a solution that provides a number and quality of locally distributed V/f domains through FOPAC. Opportunistically sharing design resources and features between multi-phase voltage regulators (MPVRs) and resonant rotary clocks (ReRoCs) enabling i) the scalability to hundreds of domains, ii) fast switching times for both voltage and frequency, leading to temporal flexibility, and iii) locally distributed designs, leading to spatial flexibility.Type: GrantFiled: May 29, 2020Date of Patent: February 8, 2022Assignee: Drexel UniversityInventors: Baris Taskin, Ragh Kuttappa, Selcuk Kose
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Publication number: 20220029457Abstract: A dynamic capacitive power transfer system for an elevator that can realize the real-time powering of the elevator when it is in the moving status. It includes a metal track along the building side as the power transmitter and a piece of metal at the elevator side as the power receiver. There is a gap between the transmitter and receiver, and up to kW power can be transferred wirelessly and efficiently to serve the air conditioner, lightning, and other electronic devices in the moving car. The steel wheels and ropes may be used to connect the moving car to the earth ground, which contributes to form the current returning loop. It eliminates the electric cables and the corresponding flexible cable carrier system for the linear movement.Type: ApplicationFiled: May 26, 2021Publication date: January 27, 2022Applicant: Drexel UniversityInventors: Fei Lu, Hua Zhang
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Patent number: 11219118Abstract: Applications of dielectric barrier discharge (DBD) based atmospheric pressure plasma jets are often limited by the relatively small area of treatment due to their 1D configuration. This system generates 2D plasma jets permitting fast treatment of larger targets. DBD evolution starts with formation of transient anode glow, and continues with development of cathode-directed streamers. The anode glow can propagate as an ionization wave along the dielectric surface through and outside of the discharge gap. Plasma propagation is not limited to 1D geometry such as tubes, and can be organized in a form of a rectangular plasma jet, or other 2D or 3D shapes. Also described are a method for generating 2D plasma jets and use of the 2D plasma jets for cancer therapy.Type: GrantFiled: February 20, 2019Date of Patent: January 4, 2022Assignees: Drexel University, Thomas Jefferson UniversityInventors: Danil V. Dobrynin, Alexander Fridman, Abraham Lin, Vandana Miller, Adam Snook
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Publication number: 20210400891Abstract: An indoor hydroponic device uses cyanobacteria as fertilizer, examining the media composition and nutrient delivery to this hydroponic unit. Due to the use of this fertilizer and the hydroponic setup, the device requires minimal space and maintenance. The device focuses on a) optimizing cyanobacteria and plant growth, b) increasing the efficacy of cyanobacteria as fertilizer, and c) evaluating and enhancing the user's experience with the hydroponic unit.Type: ApplicationFiled: July 31, 2019Publication date: December 30, 2021Applicant: Drexel UniversityInventors: Shivanthi Andandan, Diana Susan Nicholas
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Publication number: 20210403378Abstract: Manufacturing lightweight aggregate (LWA) by a sintering technique requires a delicate balance among three conditions: forming sufficient amount of molten liquid phase during sintering; reaching an appropriate viscosity for solid-liquid suspension; and emitting sufficient amount of gas that can be entrapped by the liquid phase to form pores. LWAs were made from low-calcium and high-calcium Waste Coal Combustion Ash (W-CCA) including fly ash and bottom ash. A mass fraction of at least 40% liquid phase for fly ash and 50% for bottom ash is required for a successful entrapment of emitted gaseous phases during sintering. Larger pores were observed in the microstructure of LWA samples made using high-calcium W-CCA in comparison to low-calcium W-CCA. This result was mainly attributed to the high-calcium samples forming liquid phases with lower viscosity values and emitting higher amounts of gaseous phase during sintering than did the low-calcium samples.Type: ApplicationFiled: September 9, 2021Publication date: December 30, 2021Applicant: Drexel UniversityInventors: Mohammad Balapour, Yaghoob Farnam, Yick Grace Hsuan
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Patent number: 11210396Abstract: A behavioral malware detection involves extracting features from prefetch files, wherein prefetch files; classifying and detecting benign applications from malicious applications using the features of the prefetch files; and quarantining malicious applications based on the detection.Type: GrantFiled: August 27, 2018Date of Patent: December 28, 2021Assignees: Drexel University, Temple UniversityInventors: Bander Mohamed Alsulami, Spiros Mancoridis, Avinash Srinivasan
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Patent number: 11208420Abstract: This invention outlines a method for synthesizing a blended resin system in a one pot reaction that may utilize, for example, bio-based anhydrosugars such as isosorbide as a principle component to produce isosorbide dimethacrylate and other monomeric materials for thermosetting applications. This invention establishes a one-pot procedure for reacting a hydroxy group containing compound with methacrylic anhydride in the first step and using the by-product methacrylic acid to react with glycidyl ethers to form additional methacrylate compounds in the second step. This methodology can be formulated to produce a wide array of resin systems that have controlled ratios of hydroxy group containing compound/crosslinker/reactive diluent. Additionally, the novel resin systems may be partially to fully biobased, promoting global sustainability and reducing costs, and when free radically polymerized have properties that meet or exceed their petroleum derived counterparts.Type: GrantFiled: November 16, 2017Date of Patent: December 28, 2021Assignees: Drexel University, THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMYInventors: Joshua Matthew Sadler, John Joseph La Scala, Giuseppe R. Palmese
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Patent number: 11202645Abstract: A cardioprotective patch with an integrated cutting guide includes a membrane having a top edge, a bottom edge distal from the top edge, a right side edge connecting the top edge and the bottom edge; and a left side edge, distal from the right side edge and connecting the top edge and the bottom edge. A fold extends parallel to the top edge about half way between the top edge and the bottom edge. The crease is slit from the right side edge, forming a right slit. An elongate frame is fixedly connected to the membrane. The frame includes a tubular member and a plurality of arms extending outwardly from the tubular member and connected to the membrane.Type: GrantFiled: July 10, 2018Date of Patent: December 21, 2021Assignee: Drexel UniversityInventors: Randy Stevens, Achintya Moulick, Vicki Mahan, Amy Throckmorton
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Patent number: 11202398Abstract: An electromagnetic shielding material that includes a plurality of layers, each layer having a crystal lattice represented by: Mn+1Xn (wherein M is at least one metal of Group 3, 4, 5, 6, or 7; X is a carbon atom, a nitrogen atom, or a combination thereof; and n is 1, 2, or 3), each X is positioned within an octahedral array of M, and at least one of two opposing surfaces of said each layer has at least one modifier or terminal T selected from a hydroxy group, a fluorine atom, an oxygen atom, and a hydrogen atom; and dielectric and/or magnetic nanoparticles carried on a layer surface and/or between two adjacent layers of the plurality of layers.Type: GrantFiled: September 25, 2018Date of Patent: December 14, 2021Assignees: MURATA MANUFACTURING CO., LTD., DREXEL UNIVERSITYInventors: Yoshito Soda, Takeshi Torita, Yury Gogotsi, Babak Anasori, Christine B. Hatter
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Publication number: 20210380567Abstract: A composition of matter including two optionally substituted phenol or optionally substituted aniline units separated by a furan spacer has been prepared. In particular, the chemical structure has a novolac bridge between the central furan ring and the two attached optionally substituted phenol and/or optionally substituted aniline units. These compounds can be modified to be used in various polymer resins. This new structure reduces toxicity relative to BPA/F, makes use of renewable chemicals, and produces certain beneficial polymer properties.Type: ApplicationFiled: October 10, 2019Publication date: December 9, 2021Applicants: Drexel University, The Government of the United States, as represented by the Secretary of the Army, Rowan UniversityInventors: Craig Michael PAQUETTE, John Joseph LA SCALA, Joshua Matthew SADLER, Giuseppe Rafaello PALMESE, Alexander William BASSETT, Joseph Francis STANZIONE
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Publication number: 20210361825Abstract: One aspect of the invention provides a method of treating a chronic wound including administering to the wound at least one agent from a delivery system wherein the agent induces sequential conversion of a first population of wound macrophages in the wound to M2A macrophages and a second population of wound macrophages to M2C macrophages. The sequential conversion of the wound macrophages promotes tissue remodeling.Type: ApplicationFiled: August 6, 2021Publication date: November 25, 2021Applicant: Drexel UniversityInventors: Kara L. Spiller, Sina Nassiri