Abstract: The invention relates to a curable liquid resin composition comprising: (A) a urethane(meth)acrylate having a structure originating from a polyol and a number average molecular weight of 800 g/mol or more, but less than 6,000 g/mol, and (B) a urethane(meth)acrylate having a structure originating from a polyol and a number average molecular weight of 6,000 g/mol or more, but less than 20,000 g/mol, wherein the total amount of the component (A) and component (B) is 20-95 wt % of the curable liquid resin composition and the content of the component (B) is 0.1-30 wt % of the total of the component (A) and component (B).

Abstract: The present invention relates to novel sunscreens on the basis of polysiloxanes, to their preparation and to their use, especially in formulations for the protection against harmful effects of sunlight.

Abstract: Stable needle shaped crystals of natamycin having a mean length of between 0.1 and 20 ?m.

Abstract: Genes, SNP markers and haplotypes of susceptibility or predisposition to T2D and subdiagnosis of T2D and related medical conditions are disclosed. Methods for diagnosis, prediction of clinical course and efficacy of treatments for T2D, obesity and related phenotypes using polymorphisms in the risk genes are also disclosed. The genes, gene products and agents of the invention are also useful for monitoring the effectiveness of prevention and treatment of T2D and related traits. Kits are also provided for the diagnosis, selecting treatment and assessing prognosis of T2D. Novel methods for prevention and treatment of metabolic diseases such as T2D based on the disclosed T2D genes, polypeptides and related pathways are also disclosed.

Abstract: The pressure of an antibiotic in a fluid is determined by contacting a sample of the fluid suspected of containing an antibiotic with a test medium containing a microorganism, a substance that provides a solid state and an indicator, such as Bromothymol Blue, incubating to grow the microorganism if present in the sample and detecting growth of the microorganism indicating absence of an antibiotic or inhibition of the growth of microorganism indicating the presence of an antibiotic.

Abstract: The present invention is directed to the use of a compound selected from the group consisting of ?-carotene, lutein, lycopene and ?-cryptoxanthin, and mixtures thereof and combinations thereof with CoQ-10 for maintaining the energy metabolism, the energy flow and/or the energy production in skin or of skin of animals including humans, for maintaining the respiratory function of the skin of animals including humans, for energizing the skin, maintaining and supporting the radiance and natural glow of the skin of animals including humans and for promoting a healthy appearance of the skin of animals including humans for preventing UV-A radiation-induced mtDNA mutagenesis in skin of animals including humans, as well as for the manufacture of a composition, preferably an orally applicable composition, for these uses and the corresponding methods.

Abstract: The present invention relates to novel 1,4-dihydropyridine derivatives, to novel cosmetic or dermatological sunscreen compositions containing these derivatives and the use of these derivatives for photoprotecting human skin and/or hair against UV radiation, in particular solar radiation.

Abstract: A process for the preparation of terminally ethylenically unsaturated isopolyprenols characterized in that a carbonyl compound is reacted with ethine in the presence of ammonia and low amounts of an alkaline metal hydroxide and, if desired, the terminally acetylenically unsaturated isopolyprenol obtained is partially hydrogenated in the presence of a catalyst suitable for selective hydrogenation.

Abstract: The invention relates to new processes for the preparation of antireflective coatings and coated substrates, as well as articles produced by these processes. These coatings can include one or more layers made of materials which form nano-structured and/or nano-porous surfaces. The process can include applying a cross-linkable hard coat to a substrate, partially curing or cross-linking the hard coat, and then applying a second coat carried by a solvent or mixture of solvents capable of swelling the partially cured hard coat. The second coat is then cross-linked and grafted to the hard coat to produce a durable coated substrate with antireflective properties.

Abstract: The invention is directed to a thermosetting powder paint composition comprising a thermosetting amorphous polyamide. The amorphous polyamide has a glass transition temperature between 20° C. and 200° C. The polyamide may be a carboxyl-, a hydroxyl- or an amine functional polyamide. A carboxyl functional polyamide has an acid number between 10 and 150 mg of KOH/gram of resin. The invention also relates to a thermosetting powder paint composition comprising a thermosetting amorphous polyamide and an additive comprising a copper halogenide and another halogenide. The invention further relates to a process for coating a substrate at low temperature cure (LTC) conditions and a composition suitable for LTC.

Abstract: The present invention relates to newly identified genes that encode proteins that are involved in the synthesis of L-ascorbic acid (hereinafter also referred to as Vitamin C). The invention also features polynucleotides comprising the full-length polynucleotide sequences of the novel genes and fragments thereof, the novel polypeptides encoded by the polynucleotides and fragments thereof, as well as their functional equivalents. The present invention also relates to the use of the polynucleotides and polypeptides as biotechnological tools in the production of Vitamin C from microorganisms, whereby a modification of the polynucleotides and/or encoded polypeptides has a direct or indirect impact on yield, production, and/or efficiency of production of the fermentation product in the microorganism. Also included are methods/processes of using the polynucleotides and modified polynucleotide sequences to transform host microorganisms.

Abstract: The present invention relates to compositions, preferably in the form of a powder and/or granules, which contain resveratrol and pectin, and a process for the manufacture of such compositions.

Abstract: The invention relates to coated optical fibers comprising soft primary coatings and to such primary coatings for protecting glass optical fibers having a sufficient high resistance against cavitation. In particular, the primary coatings have a cavitation strength at which a tenth cavitation appears (?10cav) of at least about 1.0 MPa as measured at a deformation rate of 0.20% min?1 and of at least about 1.4 times their storage modulus at 23° C. The coating preferably shows strain hardening in a relative Mooney plot, preferably has a strain energy release rate Go of about 20 J/m2 or more, and preferably has a low volumetric thermal expansion coefficient. The invention furthermore provides a method and apparatus for measuring the cavitation strength of a primary coating.

Abstract: The invention relates to a nucleotide sequence comprising; a synonymous nucleotide coding sequence with optimized codon frequency such that a native codon has been exchanged with a synonymous codon, the synonymous codon encoding the same amino acid as the native codon and having a higher frequency in codon usage as defined in Table 1 than the native codon; and optionally the nucleotide sequence comprises control sequences such as; one translational termination sequence orientated in 5? towards 3? direction selected from the following list of sequences; TAAG, TAGA and TAAA, preferably TAAA, and/or one translational initiator coding sequence orientated in 5? towards 3? direction selected from the following list of sequences; gctnccyyc (SEQ ID NO:20), using ambiguity codes for nucleotides; v (A/C/G); n (A/C/G/T), preferably 5?-GCT TCC TTC-3? (SEQ ID NO:21).

Abstract: The invention relates to an enantiomerically enriched chiral compound comprising a transition metal M, which comprises four, five or six coordinating groups of which at least one pair is linked together to form a bidentate ligand, in which M is directly bound via one single ?-bond to a carbon atom of an optionally substituted and/or optionally fused (hetero)aromatic ring of said bidentate ligand and in which M is directly bound to a nitrogen atom of a primary or secondary amino group of said bidentate ligand, thereby forming a metallacycle between said bidentate ligand and the metal M, said metal M being selected from the metals of groups 8 and 9 of the Periodic Table of the Elements, in particular iron, ruthenium, osmium, cobalt, rhodium, or iridium. The chiral compound can be used as a catalyst, preferably in an asymmetric transfer hydrogenation process.

Abstract: Polymers whose surfaces are modified by endgroups that include amphipathic surface-modifying moieties. An amphipathic endgroup of a polymer molecule is an endgroup that contains at least two moieties of significantly differing composition, such that the amphipathic endgroup spontaneously rearranges its positioning in a polymer body to position the moiety on the surface of the body, depending upon the composition of the medium with which the body is in contact, when that re-positioning causes a reduction in interfacial energy. An example of an amphipathic surface-modifying endgroup is one that has both a hydrophobic moiety and a hydrophilic moiety in a single endgroup. For instance, a hydrophilic poly(ethylene oxide) terminated with a hydrophilic hydroxyl group is not surface active in air when the surface-modifying endgroup is bonded to a more hydrophobic base polymer.

Abstract: A process is described for making an aqueous coating composition comprising a cationic vinyl oligomer comprising the following steps: I. preparation of a cationic vinyl oligomer by solution or bulk polymerisation of components: i) 2 to 50 wt % of vinyl monomers bearing amine functional groups selected from the group consisting of non-ionic amine functional groups (a), permanent quaternary ammonium functional groups (b), neutralised amine functional groups (c) and mixtures thereof; and ii) 20 to 98 wt % of Ci to Ci8 alkyl (meth)acrylates; and II. dispersion of the cationic vinyl oligomer in an aqueous medium and neutralisation of non-ionic amine functional groups.

Abstract: A process to produce IPP and VPP from a protein source that comprises the -I-P-P- and -V-P-P- sequence in its protein sequence and whereby at least 40% of -I-P-P- sequence present in the protein source is converted into the peptide IPP and at least 40% of the -V-P-P- sequence present in the protein source is converted into the peptide VPP, which comprises the use of a proline specific endoprotease and an amino-peptidase preferably in a single enzymatic step.

Abstract: The invention relates to a process for producing a grafted rubber comprising: a) providing an ethylene propylene rubber having a weight average molecular weight (Mw) of at least 80 kg/mol in a continuous extrusion reactor by feeding the rubber in a slab/melt dosing unit and transporting the rubber to the continuous extrusion reactor by a melt pump; b) drying the rubber in the continuous extrusion reactor to a moisture content of between about 0.2 and about 0.5 wt %; c) providing the dried rubber to a first injection zone of the continuous extrusion reactor at a temperature of between 190 and 250° C.

Abstract: The invention relates to a process for the preparation of a polymer comprising monomeric units of ethylene, an ?-olefin and a vinyl norbornene applying as a catalyst system: a. a bridged or an group 4 metal containing an unbridged catalyst having a single cyclopentadienyl ligand and a mono substituted nitrogen ligand, wherein said catalyst is defined by the formula (I): b. an aluminoxane activating compound, c. 0-0.20 mol per mol of the catalyst of a further activating compound, wherein Y is a substituted carbon or nitrogen atom. The invention further relates to a polymer obtainable with the process of the invention.