Abstract: The present invention relates to a synthesis of chromanones or chromanes in a stereospecific matter in view of the 2-position in the chromanone or chromane ring. It has been found that this synthesis is particularly possible in the presence of a chiral compound of formula of a specific.
Abstract: In the steam pelleting of feed components which include starch, the addition of an alpha-amylase to the raw material meal can reduce energy consumption (energy input) in the feed press, and increase the throughput (capacity per hour), and it may be possible to reduce the temperature in the pellet press.
Type:
Application
Filed:
June 24, 2014
Publication date:
June 2, 2016
Applicants:
Novozymes A/S, DSM IP Assets B.V.
Inventors:
Christel Thea Joergensen, Anders Viksoe-Nielsen, Dan Pettersson
Abstract: The present invention relates to a process for the production of a dicarboxylic acid and ethanol which comprises fermenting a genetically modified yeast in a suitable fermentation medium under anaerobic conditions at a pH value of between 1 and 5 and producing the dicarboxylic acid and ethanol. The invention also relates to a process for crystallizing succinic acid from an aqueous solution having a pH of between 1 and 5 and comprising succinic acid, comprising removing part of the aqueous solution by evaporation to obtain a concentrated solution, and bringing the temperature of the concentrated solution to a value of between 10 and 30 degrees Celsius, wherein succinic acid crystals are formed.
Type:
Grant
Filed:
March 23, 2010
Date of Patent:
May 31, 2016
Assignee:
DSM IP ASSETS B.V.
Inventors:
Mickel Leonardus August Jansen, Maarten Job Van de Graaf, René Verwaal
Abstract: The present invention relates to a yeast cell comprising one or more exogenous genes of a pentose metabolic pathway non-native to the yeast cell wherein the yeast cell has a disruption of the hxk1, hxk2 glk1 and gal1 native in the yeast cell. The invention further relates to pentose and glucose fermenting yeast cell that is capable of simultaneous pentose and glucose consumption.
Type:
Grant
Filed:
October 11, 2011
Date of Patent:
May 31, 2016
Assignee:
DSM IP ASSETS, B.V.
Inventors:
Hendrik Wouter Wisselink, Antonius Jeroen Adriaan Van Maris, Jacobus Thomas Pronk
Abstract: The present invention relates to a synthesis of chromanones or chromanes in a stereospecific matter in view of the 2-position in the chromanone or chromane ring. It has been found that this synthesis is particularly possible in the presence of a chiral compound of formula of a specific type and of at least one urea or thiourea.
Type:
Application
Filed:
July 3, 2014
Publication date:
May 26, 2016
Applicant:
DSM IP ASSETS B.V.
Inventors:
Ulla LETINOIS, Thomas NETSCHER, Stephan ACKERMANN
Abstract: A process for producing furfural and levulinic acid from lignocellulose-comprising biomass is disclosed. The biomass is slurried using water and optionally an acid, subjected to hydrolysis, and then subjected to a solid/liquid separation to yield at least an aqueous fraction comprising C5 and C6 sugars and a solid fraction comprising cellulose and lignin. Furfural is obtained by adding an organic solvent to the aqueous fraction, heating at 120-220° C. for a sufficient time to form furfural, cooling, and separating an organic phase comprising at least part of the furfural from an aqueous phase. Levulinic acid is obtained by suspending the solid fraction in water and optionally an acid, heating the suspension to 140-220° C., and separating an aqueous fraction comprising the levulinic acid from a solid fraction.
Type:
Grant
Filed:
July 12, 2013
Date of Patent:
May 24, 2016
Assignee:
DSM IP ASSETS B.V.
Inventors:
Johannes Gerardus De Vries, Johannes Augustinus Kroon, Rudy Francois Maria Jozef Parton, Pierre Louis Woestenborghs, Arie De Rijke
Abstract: The present invention relates to acrylic emulsion polymers as well as to their use in hair care preparations such as in particular in hair styling preparations.
Abstract: The invention relates to the use of hydroxytyrosol for inducing or enhancing cartilage repair or cartilage regeneration. Furthermore, the invention relates to nutraceutical and pharmaceutical compositions comprising hydroxytyrosol for regeneration and repair of cartilage injuries in joints, in particular of traumatic cartilage injuries.
Type:
Application
Filed:
January 21, 2016
Publication date:
May 19, 2016
Applicant:
DSM IP ASSETS B.V.
Inventors:
Daniel RAEDERSTORFF, Joseph SCHWAGER, Karin WERTZ
Abstract: The present invention is directed to a process for the manufacture of methyl limonitrile comprising a mixture of 3,7-dimethyl-2,6-nonadiene nitrile, 3,7-dimethyl-3,6-nonadiene nitrile and 7-methyl-3-methylene-6-nonene nitrile comprising the following steps: a) reacting 6-methyl-5-octen-2-one with cyano acetic acid and removing carbon dioxide and water, wherein the reaction and the removal of carbon dioxide and water are performed in the presence of a base and a co-base in an organic solvent, wherein the base is pyridine, wherein the co-base is 1,4-diamino butane, and wherein the organic solvent is a solvent which forms a heteroazeotrop with water; b) removing the solvent and pyridine of the reaction mixture obtained after having performed step a) or step c) by distillation to obtain a reaction mixture; c) isomerizing the reaction mixture obtained after having performed step a) or step b) to obtain an isomerized reaction mixture; whereby step b) can be performed before or after step c).
Type:
Grant
Filed:
February 11, 2013
Date of Patent:
May 17, 2016
Assignee:
DSM IP ASSETS B.V.
Inventors:
Raphael Beumer, Werner Bonrath, Silke Dorn, Angela Wildermann
Abstract: An aqueous emulsion comprising at least a covalently bound vinyl oligomer and vinyl polymer, wherein said vinyl oligomer comprises 5 to 85 mol % of vinyl monomers bearing quaternary ammonium ion functional groups or quaternisable amine functional groups and is obtained by a controlled radical polymerisation of at least one vinyl monomer via a reversible addition-fragmentation chain transfer mechanism in solution in the presence of a control agent and a source of free radicals; wherein said vinyl polymer is obtained by emulsion polymerisation of vinyl monomers in the presence of the vinyl oligomer; wherein the weight % ratio of vinyl oligomer to vinyl polymer is in the range of from 0.5:99.5 to 65:35.
Type:
Grant
Filed:
January 13, 2014
Date of Patent:
May 17, 2016
Assignee:
DSM IP ASSETS B.V.
Inventors:
Michael Arnoldus Jacobus Schellekens, John Geurts, Tijs Nabuurs, Gerardus Cornelis Overbeek
Abstract: The present invention relates to a process for the production of a dicarboxylic acid. The process comprises fermenting a yeast in the presence of a carbohydrate-containing substrate and low amounts of oxygen at a pH value at which at least 50% of the dicarboxylic acid is in the acid form. The process of the present invention allows for high yields of the dicarboxylic acid product and is more cost-effective than existing processes in which the salt is produced which during recovery has to be converted to the acid. It also leads to a simpler and more convenient downstream processing.
Type:
Grant
Filed:
March 19, 2015
Date of Patent:
May 17, 2016
Assignee:
DSM IP ASSETS B.V.
Inventors:
Mickel Leonardus August Jansen, Rene Verwaal
Abstract: The invention relates to aqueous compositions comprising an anionic surfactant and a hyperbranched polyesteramide having at least one quaternized amine endgroup. The compositions, in particular in the form of shampoo preparations are suited for increasing the volume of hair treated therewith. Furthermore, such compositions provide styling attributes and increase the wet-combability of hair.
Type:
Grant
Filed:
May 28, 2013
Date of Patent:
May 17, 2016
Assignee:
DSM IP ASSETS B.V.
Inventors:
Franciscus Johannes Marie Derks, Stephen Foster, Robert Lochhead, Adarsh Maini, Dirk Weber
Abstract: The present invention relates to a recombinant eukaryotic microbial cell comprising a nucleotide sequence encoding a heterologous enzyme catalyzing the conversion from phosphoenolpyruvate to oxaloacetate whereby ATP is generated. The invention further relates to a process for the preparation of a dicarboxylic acid such as succinic acid and fumaric acid, comprising fermenting the eukaryotic microbial cell according to the invention in a suitable fermentation medium.
Type:
Grant
Filed:
November 14, 2008
Date of Patent:
May 17, 2016
Assignee:
DSM IP ASSETS B.V.
Inventors:
René Verwaal, Liang Wu, Robbertus Antonius Damveld, Cornelis Maria Jacobus Sagt
Abstract: The present invention relates to novel compositions for enhancing plant growth and crop yield. Moreover, the present invention is directed to the production of these compositions and the uses of these compositions.
Abstract: Compositions containing modified gum acacia, less than 40% oil and carotenoids, where the gum acacia has been subjected to a heat-treatment at a temperature between 100° C. and 115° C. for 1 to 38 hours. These compositions allow preparation of emulsions having a very high color intensity and color stability and useful for the enrichment, fortification and/or coloration of food beverages, animal feed, cosmetics or pharmaceutical compositions.
Type:
Grant
Filed:
December 15, 2011
Date of Patent:
May 10, 2016
Assignee:
DSM IP ASSETS B.V.
Inventors:
Andrea Hitzfeld, Bruno H. Leuenberger, Olivia Vidoni
Abstract: The present invention relates to eukaryotic cells which have the ability to isomerize xylose directly into xylulose by transformation with nucleotide sequences encoding a xylose isomerase that has one or more specific sequence elements typical for isomerases which are functionally expressed in yeasts, such as xylose isomerases obtainable from bacteria of the genera Clostridium and Fusobacterium or a tunicate from the genus Ciona. The cell preferably is a yeast or a filamentous fungus capable of anaerobic alcoholic fermentation. The cells may further comprise one or more genetic modifications that increase the flux of the pentose phosphate pathway or, reduce unspecific aldose reductase activity. The cell preferably has the ability to produce a fermentation product such as ethanol, lactic acid, 3-hydroxy-propionic acid, ?-lactam antibiotics and cephalosporins. Also provided are processes for producing these fermentation products from xylose.
Type:
Grant
Filed:
December 24, 2009
Date of Patent:
May 10, 2016
Assignee:
DSM IP ASSETS B.V.
Inventors:
Aloysius Wilhelmus Rudolphus Hubertus Teunissen, Johannes Adrianus Maria De Bont
Abstract: The present invention provides a method for the transfection of filamentous fungal cells, comprising providing a multitude of containers, filling into each container an amount of polymer needed for the transfection, filling the cells to be transfected as well as an aqueous solution of transfection reagent into each of the containers, incubating the resulting mixture, removing the transfection reagent from the incubated mixture; and selecting the cells which have been transformed, characterized in that the total volume of the incubating mixture is less than 1 ml per container. Furthermore, the present invention provides the use of transformed filamentous fungal cells for the production of proteins or metabolites.
Type:
Grant
Filed:
February 27, 2014
Date of Patent:
May 10, 2016
Assignee:
DSM IP ASSETS B.V.
Inventors:
Marco Alexander Van Den Berg, Bianca Elisabeth Maria Gielesen, Adriana Marina Riemens
Abstract: The invention relates to an electrical circuit breaker comprising an arc formation chamber and an arc extinguishing chamber, the arc formation chamber being at least partially bounded by a side flange or at least a part of a side wall consisting of a polymeric composition comprising a thermoplastic polymer, a triazine based flame retardant, at most 0-5 wt. % of phosphorous or halogen containing flame retardants, and 0-15 wt. % of a reinforcing agent, wherein thermoplastic polymer comprises a polyamide with a melting temperature of at least 260° C. and the triazine based flame retardant comprises at least 20 wt. % of melam, wherein the weight percentages (wt. %) are relative to the total weight of the polymeric composition.
Type:
Grant
Filed:
June 17, 2011
Date of Patent:
May 10, 2016
Assignee:
DSM IP ASSETS B.V.
Inventors:
Rob Joseph Catharina Emiel Demandt, Johannes Hoekstra, Robert Hendrik Catharina Janssen
Abstract: This invention relates to a process for the preparation of alkenoic acid esters comprising contacting a lactone with an alcohol and an acidic catalyst in the gas phase, characterized in that the process is carried out in the presence of at least 0.26 wt. % water, relative to the amount of the lactone. The process may result in a good production yield and selectivity with respect to the production of alkenoic acid esters and may also result in less formation of dialkylethers. The improved yield advantageously allows energy conservation.
Type:
Grant
Filed:
September 21, 2012
Date of Patent:
May 10, 2016
Assignee:
DSM IP ASSETS B.V.
Inventor:
Anna Maria Cornelia Francisca Castelijns