Abstract: Intravaginal drug delivery device comprising at least one pharmaceutically active substance, and a polyurethane copolymer, wherein the copolymer has the structure according to formula (I): Also, method comprising administering one or more pharmaceutically active substances to a patient in need thereof.

Abstract: The present invention is related to a novel and improved process for the production of dehydrolinalyl acetate (DLA), which 1UPAC name is acetic acid 1-ethynyl-1,5-dimethyl-hex-4-enyl ester, starting from dehydrolinalool (DLL), which 1UPAC name is 3,7-dimethyloct-6-en-1-yn-3-ol, by acetylation.

Abstract: The invention relates to a process for compacting a polymeric powder in a press, wherein the polymeric powder is supported during compaction by a powder carrier, characterized in that said powder carrier comprises a layer of thickness (T), said layer comprising a material with a static coefficient of friction (COF), and wherein T×COF is at least 10 ?m. The invention also relates to a compacted polymeric powder obtainable with the above process.

Abstract: This invention relates to a process for the preparation of alkenoic acid esters comprising contacting a lactone with an alcohol and an acidic heterogeneous catalyst, characterized in that the process is carried out in the presence of at least 20 ppm of an acid having a pKa of 5 or less, relative to the amount of the lactone. The presence of at least 20 ppm of an acid having a pKa of 5 or less may stabilize the catalyst during the reaction and may also be used for reactivating an acidic heterogeneous catalyst. The improved yield advantageously allows energy conservation.

Abstract: The present invention relates to a recombinant host cell for the production of a compound of interest. The invention further relates to a method for the production of such host cell. The invention further relates to the production of a compound of interest. The invention further relates to isolated polynucleotides and vectors and host cells comprising said polynucleotides.

Abstract: The present invention relates to improved powderous formulations of organic acids or esters having an aromatic ring system, as well as to the production of such formulations.

Abstract: A multistory modular production plant includes a vertical stack of production modules for supporting production equipment, and a vertical stack of operator access modules adjacently connected to the vertically stacked production modules to allow operator access to the production modules. The adjacently connected vertical stacks of production modules and operator access modules thereby establish multiple stories of the modular production plant. Stairs and/or an elevator may be provided in the vertical stack of operator access modules to allow an operator to ascent/descend between stories of the plant. In especially preferred embodiments, each production module and operator access module is in the form of a rectangular parallelepiped which is sized so as to be accommodated within a standard 20-foot shipping container. This configuration of modular units thus allows the plant to be more quickly shipped and constructed on site.

Abstract: The invention relates to a branched polyamide prepolymer obtained or obtainable by polymerization of a polyamide forming monomer mixture, comprising AA-BB repeat units and branching units derived from diamines (monomer A) dicarboxylic acids (monomer B), and/or a salt of A and B, and a higher functional monomer (monomer C) present in a molar amounts defined by formula I and formula II: MC=(Q/FC)*(MA+MB) (Formula I) and R=((MA*2)+(MC*FCA))/((MB*2)+(MC*FCB)) (Formula II) wherein—MA, MB and MC represent the molar amounts of repeat units derived from the monomers A, B and C, respectively; —FC represent the functionality of monomer C, and is equal to FC-A+FC-B; —FC-A is the number of the amino functional groups comprised by monomer C; —FC-B is the number of carboxyl functional groups or precursor groups thereof comprised by monomer C; —Q is a number in the range of 0.06-1.00; and —R is a number in the range of 0.7-1.

Abstract: The invention is directed to a macromer comprising unit derived from a siloxane diol, di-isocyanates and a diol comprising a pendant group comprising an oligomer or polymer derived from methyl oxazoline or ethyl oxazoline. The invention also relates to a process for the preparation of said macromers, and to that the use of said macromers. The macromers according to the invention may be used in lenses, such as ophthalmic lenses. Films comprising the macromers according to the invention provide a surprisingly low modulus in combination with a high water content and oxidative stability.

Abstract: The present invention relates to feed supplements comprising vitamins and canthaxanthin and the use of such supplements for improving performance and health in poultry, in particular in poultry pullets. It has been found surprisingly that feed additive compositions as hereinafter defined improves immune status, bone and skeletal development, flock uniformity, growth and feed conversion of pullets. The feed additive composition according to the present invention comprises canthaxanthin, at least one vitamin selected from the group consisting of vitamin C and vitamin E, a trace mineral, in particular selenium, and optionally a mixture of at least two compounds selected from the group consisting of thymol, eugenol, vanillin and ?-terpinene.

Abstract: The present invention relates to a improved process for the biotechnological production of compounds for which ribose-5-phosphate, ribulose-5-phosphate or xylulose-5-phosphate is biosynthetic precursor like riboflavin (vitamin B2), FAD, FMN, pyridoxal phosphate (vitamin B6), guanosine, GMP, adenosine, AMP. The invention further pertains to the generation of the organism producing those compounds. It furthermore relates to the generation of mutated transketolases that allow normal growth on glucose but reduced growth on gluconate when introduced into the production strains and to polynucleotides encoding them.

Abstract: The invention relates to a polyamide comprising units derived from: A. a diamine comprising in its structure at least one cyclohexane fragment according to Structure I, in which the substituents are in the 1,4-trans-position (Structure I), with n a positive integer of at least 1, and the proviso that when n is 2 or higher the cyclohexane rings are connected to each other through the 1,4-trans position, B. an aliphatic dicarboxylic acid with at least 13 carbon atoms and optionally comprising units derived from: C. one or more aliphatic dicarboxylic acids other than B, D. one or more diamines other than A, E. one or more monofunctional carboxylic acids or monofunctional amines, F. one or more polyfunctional monomers comprising carboxylic acid and/or amine groups, G. one or more lactams or corresponding amino acids. The invention further relates to a composition comprising such a polyamide and its uses.

Abstract: The invention relates to a method for producing a highly oriented, high molecular weight polymer tape. The method comprises forming and compression-molding a polymer powder bed at a temperature below the melting point of the polymer to form a sheet; at a temperature below the melting point of the polymer, rolling and stretching the sheet in a calendar unit to form a partially oriented polymer web; at a temperature below the melting point of the polymer, drawing the partially oriented polymer web in a drawing unit; and, optionally repeating step c) to form a more fully oriented non-fibrous high molecular weight polymer tape, the method being discontinuous in that the ingoing line speed of one of the method steps b) to d) differs from the outgoing line speed of the preceding method step.

Abstract: The process of the present invention comprises reacting an aldehyde or ketone with an alcohol in the presence of a solid acid, and removing water and methanol from the reaction product by pervaporation, characterized in that a membrane having a flux density for water of 0.04 to 2.8 kg/(hm2) is used to remove the water and another membrane having a flux density for methanol of 2.0 to 100 kg/(hm2) is used to remove the methanol.

Abstract: The present invention is concerned with a process for preparing acetals and ketals which comprises (i) reacting an aldehyde or ketone with an alcohol in the presence of a solid acid at a temperature of below ?40° C., and (ii) removing water and lower aliphatic alcohol and/or sugar alcohol from the reaction product by pervaporation.

Abstract: This invention relates to a fuel part, comprising a polymer composition comprising: i. a polyamide A in which the ratio of terminal carboxy group concentration over terminal amino group concentration of the polyamide A is equal to 1 or higher, and ii. micro talcum in an amount of 0.001 to 1 weight percent with respect to the total amount of the polymer composition, and iii. an impact modifier in an amount of at least 1.0 weight percent with respect to the total amount of the polymer composition. This invention also relates to a process for producing a fuel part.

Abstract: A pellet comprising glass fibers and a thermoplastic polyester matrix, wherein the glass fiber at least partially has been coated with a two-part sizing composition comprising: (C) A precursor comprising: (a) an aminosilane and (b) a polymer or copolymer containing carboxylic acid and/or anhydride, both having a functionality, F?3, and (D) A binder comprising a multifunctional epoxy resin of functionality, F?3, and wherein the pellet has been subjected to a solid state post condensation process (SSPC).

Abstract: The present invention relates to novel lipase polynucleotide sequences, their corresponding proteins as well as ways of manufacturing said sequences and said proteins and use of the proteins in the preparation of food compositions. The invention further relates to methods for releasing proteins from the exterior of a host cell as well as to a method for killing micro-organisms.

Abstract: The present invention relates to compounds of formula (I) wherein R1 signifies a C1-C15 alkyl moiety or a C2 to C18 alkenyl moiety, to their process of production as well as to their use in organic synthesis, especially as intermediates (building blocks) in the synthesis of vitamin A or ?-carotene or derivatives thereof, or other carotenoids, e.g. canthaxanthin, astaxanthin or zeaxanthin, preferably vitamin A.

Abstract: The invention relates to an eukaryotic cell expressing nucleotide sequences encoding the ara A, ara B and ara D enzymes whereby the expression of these nucleotide sequences confers on the cell the ability to use L-arabinose and/or convert L-arabinose into L-ribulose, and/or xylulose 5-phosphate and/or into a desired fermentation product such as ethanol. Optionally, the eukaryotic cell is also able to convert xylose into ethanol.