Patents Assigned to DSM
  • Publication number: 20150112057
    Abstract: The present invention relates to a crystalline form of an intermediate for cefoperazone of formula (1) and to a process for the preparation thereof by enzymatic condensation of a 3?-thiosubstituted ?-lactam nucleus with a phenylglycine derivative.
    Type: Application
    Filed: June 21, 2012
    Publication date: April 23, 2015
    Applicant: DSM Sinochem Pharmaceuticals Netherlands B.V.
    Inventors: Harold Monro Moody, Claudia Cusan, Edwin Gerard Ijpeij
  • Publication number: 20150112091
    Abstract: The present invention relates to compounds of formula (I) wherein R1 signifies a C1-C15 alkyl moiety or a C2 to C18 alkenyl moiety, to their process of production as well as to their use in organic synthesis, especially as intermediates (building blocks) in the synthesis of vitamin A or ?-carotene or derivatives thereof, or other carotenoids, e.g. canthaxanthin, astaxanthin or zeaxanthin, preferably vitamin A.
    Type: Application
    Filed: June 14, 2012
    Publication date: April 23, 2015
    Applicant: DSM IP ASSETS
    Inventors: Werner Bonrath, Thomas Netscher, Jan Schütz, Bettina Wüstenberg
  • Patent number: 9011948
    Abstract: Process for producing a dairy product by adding a lactase to a dairy product which contains lactose, the lactase added having less than 40 units arylsulfatase activity per NLU of lactase activity.
    Type: Grant
    Filed: November 28, 2006
    Date of Patent: April 21, 2015
    Assignee: DSM IP Assets B.V.
    Inventors: Petrus Jacobus Theodorus Dekker, Luppo Edens, Maximiliaan Peter Marie De Swaaf, Albertus Alard Van Dijk
  • Patent number: 9012616
    Abstract: The present invention relates to recombinant cells and microorganisms of the phylum Labyrinthulomycota and their use in heterologous protein production. Novel promoter, terminator, and signal sequences for efficient production and, optionally, secretion of polypeptides from recombinant host cells and microorganisms are also encompassed by the present invention.
    Type: Grant
    Filed: December 17, 2013
    Date of Patent: April 21, 2015
    Assignee: DSM IP Assets B.V.
    Inventors: Kirk E. Apt, James Casey Lippmeier, David Simpson, Jun Wang, James P. Wynn, Ross Zirkle
  • Patent number: 9012187
    Abstract: The present invention relates to a process for the production of a dicarboxylic acid. The process comprises fermenting a yeast in the presence of a carbohydrate-containing substrate and low amounts of oxygen at a pH value at which at least 50% of the dicarboxylic acid is in the acid form. The process of the present invention allows for high yields of the dicarboxylic acid product and is more cost-effective than existing processes in which the salt is produced which during recovery has to be converted to the acid. It also leads to a simpler and more convenient downstream processing.
    Type: Grant
    Filed: May 20, 2009
    Date of Patent: April 21, 2015
    Assignee: DSM IP Assets B.V.
    Inventors: Mickel Leonardus August Jansen, René Verwaal
  • Patent number: 9012027
    Abstract: The invention relates to an aqueous emulsion comprising at least a vinyl polymer, said vinyl polymer comprising: a) 45 to 99 wt % of itaconate ester monomers having formula (I), wherein R and R? are independently an alkyl or an aryl group; b) 0.1 to 15 wt % of ionic or potentially ionic unsaturated monomers; c) 0 to 54 wt % of unsaturated monomers, different from a) and b); and 0.9 to 54.9 wt % by weight of total monomers of a chaser monomer composition added subsequently and polymerized after the polymerization of monomers a), b) and c); wherein a)+b)+c) and the chaser monomer composition add up to 100%; and wherein the aqueous emulsion contains less than 0.5 wt % free itaconate ester monomers of formula I based on the total weight of the aqueous emulsion.
    Type: Grant
    Filed: December 17, 2010
    Date of Patent: April 21, 2015
    Assignee: DSM IP Assets B.V.
    Inventors: Tijs Nabuurs, Gerardus Cornelis Overbeek, Jeffrey Stubbs
  • Patent number: 9006318
    Abstract: The present invention relates to a polyamide composition comprising (amounts are based on the total composition) (A) polyamide, (B) melamine cyanurate and (C) talcum as mineral filler wherein the amount of talcum is higher than 25 wt %, and the weight ratio melamine cyanurate/talcum is higher than ? and to articles made wholly or partly of this polyamide composition. The polyamide is preferably polyamide 6. The composition is commonly used in the industry of for instance electrical and electronic parts and preferably in miniature circuit breakers.
    Type: Grant
    Filed: July 8, 2009
    Date of Patent: April 14, 2015
    Assignee: DSM IP Assets B.V.
    Inventors: Johannes Hoekstra, Jeroen Joost Crevecoeur, Jin Ye
  • Patent number: 9006391
    Abstract: The present invention relates to a method for preparing cyclopeptides by means of protection with a substituted boronic acid. The present invention also discloses novel boronate esters of cyclopeptides of general formula (8).
    Type: Grant
    Filed: May 6, 2010
    Date of Patent: April 14, 2015
    Assignee: DSM Sinochem Pharmaceuticals Netherlands B.V.
    Inventors: Robertus Mattheus De Pater, Dhiredj Chandre Jagesar, Thomas Van Der Does
  • Patent number: 9005753
    Abstract: The invention relates to a process for producing gel-spun ultra high molecular weight polyethylene (UHMWPE) fibres having high tensile strengths and improved creep rates wherein the UHMWPE used in said process is characterized by a difference in the phase angle according to Formula (1) ??=?0.001??100 of at most 42°, wherein ?0.001 is the phase angle at an angular frequency of 0.001 rad/sec; and ?100 is the phase angle at an angular frequency of 100 rad/sec as measured with a frequency sweep dynamic rheological technique at 150° C. on a 10% solution of UHMWPE in paraffin oil, provided that ?100 is at most 18°. The invention further relates to gel-spun UHMWPE fibres produced thereof. The gel-spun UHMWPE fibres of the invention have a tensile strength of at least 4 GPa, and a creep rate of at most 5×10?7 sec?1 as measured at 70° C. under a load of 600 MPa.
    Type: Grant
    Filed: October 6, 2008
    Date of Patent: April 14, 2015
    Assignee: DSM IP Assets B.V.
    Inventors: Joseph Arnold Paul Maria Simmelink, Paulus Antonius Maria Steeman
  • Patent number: 8999680
    Abstract: The present invention relates to a novel method for the preparation of 1,4-diaminobutane [DAB]. The method according to the present invention involves at least one biocatalytic step which comprises the biocatalytic production of at least one N-protected precursor of DAB. The present invention also relates to a method for the preparation of DAB involving at least one biocatalytic step, and comprising the steps of a) biocatalytically preparing an N-protected precursor of DAB yielding a—biocatalytic reaction mixture containing the N-protected precursor of DAB, b) recovering the N-protected precursor from the biocatalytic reaction mixture and c) converting the N-protected precursor into DAB. More in particular, the present invention relates to a method for the preparation of DAB, wherein the at least N-protected precursor of DAB is selected from the group consisting of N5-protected ornithine, N-protected DAB, and N-protected 4-aminobutyraldehyde.
    Type: Grant
    Filed: July 20, 2010
    Date of Patent: April 7, 2015
    Assignee: DSM IP Assets B.V.
    Inventors: Liang Wu, Petronella Catharina Raemakers-Franken
  • Patent number: 8999494
    Abstract: The invention relates to a polyesteramide resin containing ester groups and at least one amide group in the back-bone characterized in that it has at least one hydroxyalkylamide endgroup, and a Tg<0° C.
    Type: Grant
    Filed: July 16, 2010
    Date of Patent: April 7, 2015
    Assignee: DSM IP Assets B.V.
    Inventors: Franciscus Johannes Marie Derks, Jelle Bernandas Otto Van der Werf
  • Patent number: 8999866
    Abstract: Ballistic-resistant assemblies include monolayers formed of high-performance polyethylene multi-filament yarns. The assemblies have an areal density of at least 1.5 kg/m2 and a specific energy absorption of at least 300 J·m2/kg as measured against a 9*19 mm FMJ Parabellum bullet according to a test procedure based on Stanag 2920.
    Type: Grant
    Filed: August 28, 2013
    Date of Patent: April 7, 2015
    Assignee: DSM IP Assets B.V.
    Inventors: Joseph Arnold Paul Maria Simmelink, Jacobus Johannes Mencke, Martinus Johannes Nicolaas Jacobs, Roeloef Marissen
  • Patent number: 8993037
    Abstract: The present invention relates to an improved process for the preparation of an extract enriched in dihydrochalcones, and more specifically enriched in phlorizin, starting from a dry polyphenolic fraction originating from industrial apple processing. The invention also relates to a dihydrochal-cone extract obtainable by this process, and to a food or a nutraceutical product comprising a dihydrochalcone extract of the present invention.
    Type: Grant
    Filed: January 19, 2012
    Date of Patent: March 31, 2015
    Assignee: DSM IP Assets B.V.
    Inventors: Bettina Boehlendorf, Hubert Hug, Judith Kammerer, Claus Kilpert, Reinhold Carle
  • Patent number: 8987480
    Abstract: The present invention relates to a process of separating chiral isomers of chroman compounds, particularly tocopherols and tocotrienols as well as the esters and intermediates thereof. It has been found that this process allows a separation of the desired isomer with a higher yield and enables the use of the non-desired isomers in a very efficient way. Said process is particularly useful when implemented in an industrial process. Furthermore, it has been found that this process allows using isomer mixtures as they result from traditional industrial synthesis.
    Type: Grant
    Filed: May 8, 2012
    Date of Patent: March 24, 2015
    Assignee: DSM IP Assets B.V.
    Inventors: Gerhard Schiefer, Thomas Netscher, Alexander Lucia Leonardus Duchateau
  • Patent number: 8987478
    Abstract: The present invention relates to a process for the preparation of a precursor for the synthesis of hexanoic acid derived statins and to the use of said precursor in the manufacture of a medicament.
    Type: Grant
    Filed: December 6, 2012
    Date of Patent: March 24, 2015
    Assignee: DSM Sinochem Pharmaceuticals Netherlands B.V.
    Inventors: Ben De Lange, Dennis Heemskerk, Karin Henderika Maria Bessembinder
  • Patent number: 8986773
    Abstract: A process to prepare packaged pasteurized or sterilized aqueous drinkable products which comprise casein micelles (e.g. from dairy protein) and peptide-fractions, which peptide fractions are rich in tryptophan, and the products so-obtained. The process requires a heat preservation at a specific pH.
    Type: Grant
    Filed: April 9, 2009
    Date of Patent: March 24, 2015
    Assignee: DSM IP Assets B.V.
    Inventors: Rudolf Beckhoven Van, Arjen Bot, Alexander Duchateau, Luppo Edens, Joris Kloek, Andre L Ross De
  • Patent number: 8986800
    Abstract: Cooking bag containing a copolymer containing monomer units of a dimerised fatty acid or a derivative thereof. Use the cooking bag for cooking food. A process for storing and cooking of food comprising the steps: a) filling the cooking with food, b) storing the filled cooking bag at a temperature below 0° C., c) cooking the food.
    Type: Grant
    Filed: September 7, 2010
    Date of Patent: March 24, 2015
    Assignee: DSM IP Assets B.V.
    Inventors: Atze Jan Nijenhuis, Paul Willem Jan Van Den Heuvel, Paul Alexander Moruzi
  • Publication number: 20150075465
    Abstract: The invention relates to rotor body for a variable valve timing system, comprising a main body comprising a front side, a back side and vanes tips, made from a fibrous reinforced polymeric material, a central part comprising an (axial) bore hole made of metal, and sealing elements made of a non-reinforced polymeric material at the vain tips and at the front side and back side. The invention also relates to a variable valve timing system comprising an assembly of a rotor and a stator receiving the rotor on a camshaft, wherein the rotor is a rotor body as described above, wherein an end part of the camshaft and/or a fixing element is received in the bore hole and the rotor is fixed at the end part of the camshaft with the fixing element.
    Type: Application
    Filed: April 26, 2013
    Publication date: March 19, 2015
    Applicant: DSM IP ASSETS B.V.
    Inventors: Jeff Harding, Carl Howarth, Bill Burnham
  • Patent number: 8980971
    Abstract: A photocurable resin composition for three-dimensional photofabrication operations, including stereolithography, comprising (A) a cationically polymerizable compound having two or more bisphenol structures and one or more hydroxyl groups, (B) a cationically polymerizable compound other than the component (A), (C) a cationic photoinitiator, (D) a radically polymerizable compound, (E) a radical photoinitiator, and (F) multilayer polymer particles having a core and a shell layer, the shell layer containing functional group-modified rubber polymer particles having at least one reactive functional group.
    Type: Grant
    Filed: May 21, 2013
    Date of Patent: March 17, 2015
    Assignee: DSM IP Assets B.V.
    Inventors: Masahiro Ueda, Katsuyuki Takase, Takahiko Kurosawa
  • Patent number: 8980335
    Abstract: The present invention relates to a novel feed composition for animals, for example poultry, comprising as active ingredient benzoic acid, derivatives or metabolites thereof, in combination with a mixture of at least two active compounds selected from the group consisting of thymol, eugenol and piperine. The inventors found that in addition to the well known function of benzoic acid, this compound can be used as a potential growth promoter when it is combined with a mixture of at least two active compounds selected from the group consisting of thymol, eugenol and piperine. In particular the inventors have been able to demonstrate that a mixture of these chemical compounds present in different parts of plants, used in synergy and in combination with an appropriate amount of benzoic acid, exhibits, in totally unexpected manner, the effects sought by the present invention of improving the digestibility of poultry feed, i.e. for improving feed conversion ratio and/or daily weight gain in animal.
    Type: Grant
    Filed: June 25, 2008
    Date of Patent: March 17, 2015
    Assignee: DSM IP Assets B.V.
    Inventors: Marco Frehner, Christophe Paulus, Petra Philipps, Martin Gadient