Abstract: There is described (pref. non-adhesive) coating compositions (which may be either water or solvent borne) that comprise an autoxidisable vinyl polymer, the autoxidisable polymer having a vinyl polymer backbone 25% to 75% by wt of the autoxidisable polymer; fatty acid residue 25% to 75% by wt of the autoxidisable polymer; Tg from ?60° C. to +20° C., Mw from 3500 to 50000 g/mol; and polydispersity from 2 to 10; the autoxidisable polymer obtained by a process of: (A) polymerising ethylenically unsaturated vinyl monomers comprising: at least one epoxy functional vinyl monomer 15% to 100% by wt total monomers in (A); 0 to 85% of at least one other ethylenically unsaturated vinyl monomer, (preferably other than styrenic monomers) by wt total monomers in (A); (B) reacting the epoxy functional polymer from (A) with fatty acids having an average iodine value from 30 to 250 g I2/100 g fatty acid; where composition has: a) a opt.
Type:
Grant
Filed:
April 16, 2013
Date of Patent:
February 3, 2015
Assignee:
DSM IP Assets B.V.
Inventors:
Gerardus Cornelis Overbeek, Ilse van Casteren, Ronald Tennebroek, Jelle Bernardus Otto van der Werf
Abstract: Disclosed are nucleic acid and amino acid sequences for acetolactate synthase, acetolactate synthase regulatory regions, ?-tubulin promoter, a promoter from a Thraustochytriales polyketide synthase (PKS) system, and fatty acid desaturase promoter, each from a Thraustochytriales microorganism. Also disclosed are recombinant vectors useful for transformation of Thraustochytriales microorganisms, as well as a method of transformation of Thraustochytriales microorganisms. The recombinant nucleic acid molecules of the present invention can be used for the expression of foreign nucleic acids in a Thraustochytriales microorganism as well as for the deletion, mutation, or inactivation of genes in Thraustochytriales microorganisms.
Type:
Grant
Filed:
June 21, 2013
Date of Patent:
February 3, 2015
Assignee:
DSM IP Assets B.V.
Inventors:
Paul G. Roessler, T. Dave Matthews, Tom M. Ramseier, James G. Metz
Abstract: The present invention relates to a method for the production of a compound of interest by microbial fermentation, wherein the microbial host cell used has been modified in its genome such that it results in a deficiency in the production of at least one non-ribosomal peptide synthase. The present invention further relates to a microbial host cell that has been modified in its genome such that it results in a deficiency in the production of at least one non-ribosomal peptide synthase. The invention further relates to a compound of interest.
Type:
Grant
Filed:
July 1, 2011
Date of Patent:
February 3, 2015
Assignee:
DSM IP Assets B.V.
Inventors:
Noel Nicolaas Maria Elisabeth Van Peij, Marcus Hans, Martina Beishuizen, Dick Schipper, Robertus Antonius Mijndert Van Der Hoeven, Olaf Leonardus Schouten
Abstract: Hydroxytyrosol or olive juice containing hydroxytyrosol in combination with at least one of the compounds selected from the group consisting of: creatine, coenzyme Q10, resveratrol, caffeine, carnitine, B vitamins (B1, B2, B3, B5, B6, and/or B12) and ginseng (preferably: root) extract. can be used to maintain or increase mitochondrial biogenesis in cardiac muscle, skeletal muscles, and liver tissue.
Type:
Application
Filed:
August 1, 2014
Publication date:
January 29, 2015
Applicant:
DSM IP ASSETS B.V.
Inventors:
Ann FOWLER, Angelika FRIEDEL, Darko KNUTTI, Karin KURATLI, Daniel RAEDERSTORFF, Ying WANG-SCHMIDT, Karin WERTZ
Abstract: The present invention relates to microorganisms genetically engineered to increase yield and/or efficiency of biomass production from a carbon source, such as e.g. glucose. Processes for generating such microorganisms are also provided by the present invention. The invention also relates to polynucleotide sequences comprising genes that encode proteins that are involved in the bioconversion of a carbon source such as e.g. glucose into biomass. The invention also features polynucleotides comprising the full-length polynucleotide sequences of the novel genes and fragments thereof, the novel polypeptides encoded by the polynucleotides and fragments thereof, as well as their functional equivalents. Also included are processes of using the polynucleotides and modified polynucleotide sequences to transform host microorganisms leading to a microorganism with reduced carbon source diversion, i.e. higher yield and/or efficiency of biomass production from a carbon source such as e.g. glucose.
Abstract: The present invention is directed to isolated nucleic acid molecules and polypeptides of thraustochytrid polyunsaturated fatty acid (PUFA) synthases involved in the production of PUFAs, including PUFAs enriched in docosahexaenoic acid (DHA), eicosapentaenoic acid (EPA), or a combination thereof. The present invention is directed to vectors and host cells comprising the nucleic acid molecules, polypeptides encoded by the nucleic acid molecules, compositions comprising the nucleic acid molecules or polypeptides, and methods of making and uses thereof.
Type:
Grant
Filed:
March 19, 2010
Date of Patent:
January 27, 2015
Assignee:
DSM IP Assets B.V.
Inventors:
Kirk E. Apt, Leslie Richter, David Simpson, Ross Zirkle
Abstract: A process for the isolation of desired compound(s) from a microbial biomass is disclosed, wherein the microbial biomass (which, if necessary, is pretreated to give a dry matter content of from 25 to 80%) is granulated (e.g. by extrusion) and then dried to a dry matter content of at least 80%. The granulation of the biomass to granules significantly eases subsequent drying of the biomass (which can be stored as dried granules) and gives higher yields on extraction of the compound(s).
Type:
Application
Filed:
March 28, 2014
Publication date:
January 22, 2015
Applicant:
DSM IP Assets B.V.
Inventors:
Hendrik Louis BIJL, Albert SCHAAP, Johannes Martinus Jacobus VISSER
Abstract: Die (1) for strand pelletizing a polymer composition, wherein the die surface (4) adjacent to the outflow opening (2) of the die is coated with a ceramic coating (5) or a polytetrafluorethylene containing coating.
Abstract: The present invention is related to a new metal powder catalytic system (catalyst) comprising a cobalt/chrome-alloy as a carrier, its production and its use in hydrogenation processes.
Abstract: Process for enhancing the color intensity of a colored molded UHMWPE article comprising the steps of a) providing an UHMWPE, a coloring agent and a color enhancer, b) molding the UHMWPE into a molded article, c) adding the color enhancer to the UHMWPE before or during the molding step and d) adding the coloring agent to the UHMWPE before, during or after the molding step, wherein the color enhancer is a material with a hardness higher than the hardness of the molded article measured in the absence of the color enhancer.
Type:
Application
Filed:
February 15, 2013
Publication date:
January 15, 2015
Applicant:
DSM IP ASSETS B.V.
Inventors:
Giovanni Joseph Ida Henssen, Peto Verdaasdonk
Abstract: The present invention relates to process for the maintaining of a ratio stereoisomers of carotenoid compounds, to specific formulations and to the use of such specific formulations.
Type:
Application
Filed:
July 6, 2012
Publication date:
January 8, 2015
Applicant:
DSM IP ASSETS B.V.
Inventors:
Dan Pertig, Christian Schäfer, Joachim Ulrich, Elodie Verdurand
Abstract: Compositions consisting of or comprising resveratrol and a protective colloid, particularly a gelatine, a modified food starch or a ligninsulfonate, their use for stably incorporating resveratrol into water-based foods, particularly beverages, and the foods thus obtained.
Type:
Grant
Filed:
February 3, 2010
Date of Patent:
January 6, 2015
Assignee:
DSM IP Assets B.V.
Inventors:
Sylvain Diguet, Nicolle Goetz, Bruno H. Leuenberger, Johann Ulm, Loni Schweikert
Abstract: There are described vinyl sequential copolymers (and processes for making them) comprising (a) at least 8. 5 wt-% preferably >=20 wt-% of a higher itaconate diester (preferably dibutyl itaconate—DBI); (b) less than 23 wt-% acid monomer but also sufficient to have an acid value less than 150 mg KOH/g of polymer, (c) optionally with less than 50 wt-% of other itaconate monomers, and (d) optionally less than 77 wt-% of other monomers not (a) to (c). The DBI may be biorenewable. One embodiment is an aqueous dispersion of the vinyl sequential polymer of two phases: A) 40 to 90 wt-% of a vinyl polymer A with Tg from ?50 to 30° C.; and B) 10 to 60 wt-% of a vinyl polymer B with Tg from 50 to 130° C.; where DBI is used to prepare A and/or B and polymer A has from 0.1 to 10 wt-% of at least one acid-functional olefinically unsaturated monomer.
Type:
Application
Filed:
February 4, 2013
Publication date:
January 1, 2015
Applicant:
DSM IP ASSETS B.V.
Inventors:
Tijs Nabuurs, Gerardus Cornelis Overbeek, Jeffrey Stubbs, Matthew Stewart Gebhard
Abstract: The present invention relates to a structured catalyst based on sintered metal fibers (SMF) coated by a non-acidic metal oxide layer impregnated with Pd and Agnanopartides, characterized in that the ratio of the Pd:Ag is 1:1 to 10:1, as well as the use of such a catalyst in selective catalytic hydrogenations of organic compounds.
Type:
Application
Filed:
October 26, 2012
Publication date:
January 1, 2015
Applicant:
DSM IP ASSETS B.V.
Inventors:
Werner Bonrath, Lioubov Kiwi-Minsker, Igor Iouranov
Abstract: The invention relates to a substantially laminary manufacture comprising 2 substantially laminary layers in contact, wherein the layers comprise a woven, hydrophilic material.
Type:
Application
Filed:
December 21, 2012
Publication date:
January 1, 2015
Applicant:
DSM IP ASSETS B.V.
Inventors:
Ynze Mengerink, Johannes Helena Michael Mommers, Jun Qiu
Abstract: The invention relates to anti-ballistic articles comprising a stack of sheets, each sheet having one or more mono-layers of polyethylene anti-ballistic fibers and a thermoplastic binder, wherein the specific energy absorption (SEA) of the anti-ballistic article is greater than 145 J/kg/m2 and the maximum % thickness increase, measured at about 90° C., is less than 8% after storing the article for 160 hours at 90° C.
Abstract: Use of pure lanthanum oxide which is obtained by calcination of oxygen-containing lanthanum salts at temperatures of at least 700° C. as heterogeneous catalyst in the aldol condensation of citral and acetone to give pseudoionone, and process for the preparation of pseudoionone by aldol condensation of citral and acetone in the liquid phase using pure lanthanum oxide.
Type:
Grant
Filed:
July 19, 2011
Date of Patent:
December 30, 2014
Assignee:
DSM IP Assets B.V.
Inventors:
Wolfgang Hölderich, Verena Ritzerfeld, Bernhard Markus Ernst Russbüldt, Erhard Henning Fleischhauer, Werner Bonrath, Reinhard Karge, Jan Schütz
Abstract: Disclosed are compositions and methods related to eukaryotic microorganisms that can produce unsaturated fatty acids which can be purified and used.
Type:
Grant
Filed:
March 22, 2012
Date of Patent:
December 30, 2014
Assignee:
DSM Nutritional Products AG
Inventors:
Adam M. Burja, Helia Radianingtyas, Colin James Barrow, Anthony James Windust
Abstract: The invention relates to an isolated polypeptide having esterase activity comprising an amino acid sequence shown in any one of SEQ ID NO's 2, 4, 6, 8, 10, 12 or 14 or a homologue thereof, comprising an amino acid substitution or deletion of one or more amino acids as shown in said SEQ ID NO's and resulting in a mutant polypeptide having an increased concentration of the fraction of the mutant polypeptide being present as an active and soluble protein in cleared lysate of the mutant polypeptide expressed in E. coli relative to the concentration of the fraction of the polypeptide without the mutation being present as an active and soluble protein in cleared lysate of the polypeptide without the one or more deletion or substitution expressed in E. coli under the same conditions. The invention also relates to nucleic acid encoding the polypeptides according to the invention, and the use of the polypeptides.
Type:
Grant
Filed:
April 26, 2010
Date of Patent:
December 30, 2014
Assignee:
DSM IP Assets B.V.
Inventors:
Martin Kietzmann, Harald Pichler, Helmut Schwab, Amin El-Heliebi, Christine Winkler, Andreas Braun