Patents Assigned to DSM
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Publication number: 20140106914Abstract: The invention relates to a chain guide, respectively a chain tensioner for use in a lubricated sliding system, comprising a surface layer or bearing or comprising a sliding element comprising a surface layer, the surface layer being mainly made of a polymeric material containing a matrix polymer and optionally other components dispersed in said matrix polymer, wherein the matrix polymer consists of a semi-crystalline polyamide (SCPA) having a tensile modulus at 140° C. of at least 800 MPa (measured by the method according to ISO 527-1A). The invention also relates to a power train drive system comprising an engine, a transmission differential and a drive shaft system, a drive chain and a plastic component comprising a sliding element in contact with the lubricated drive chain, wherein the chain guide, the chain tensioner, respectively the sliding element has a coefficient of friction (Co F), measured in lubrication oil at 140° C. at a nominal contact pressure of 1 MPa and a speed of 1 m/s, of at most 0.07.Type: ApplicationFiled: December 21, 2011Publication date: April 17, 2014Applicant: DSM IP ASSETS B.V.Inventors: Roy Antoine Hendrikus Wilhelmus Proost, Michael Hubertus Helena Meuwissen, Zhujuan Wang
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Publication number: 20140107290Abstract: A process for obtaining an aqueous emulsion comprising a block copolymer by the solution polymerisation of vinyl monomers to obtain block [B] in the presence of a) a radical precursor; and b) an iodine atom containing block [A]; where block [A] and [B] together comprise 0 to 2 wt % of methacrylic acid; where block [A] and block [B] together comprise ?2.5 wt % of vinyl monomers bearing ionic or potentially ionic water-dispersing groups not including methacrylic acid; and performing a post polymerisation reaction on the block copolymer emulsion obtained in step II; and wherein said aqueous emulsion has a free vinyl monomer level <1000 ppm when having a solids content of ?20 wt %.Type: ApplicationFiled: December 24, 2013Publication date: April 17, 2014Applicant: DSM IP ASSETS B.V.Inventors: Tijs NABUURS, Gerardus Cornelis OVERBEEK, Michael Arnoldus Jacobus SCHELLEKENS, Danny VISSER, Frank VAES
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Publication number: 20140106402Abstract: The present invention relates to recombinant cells and microorganisms of the phylum Labyrinthulomycota and their use in heterologous protein production. Novel promoter, terminator, and signal sequences for efficient production and, optionally, secretion of polypeptides from recombinant host cells and microorganisms are also encompassed by the present invention.Type: ApplicationFiled: December 17, 2013Publication date: April 17, 2014Applicant: DSM IP Assets B.V.Inventors: Kirk E. APT, James Casey LIPPMEIER, David SIMPSON, Jun WANG, James P. WYNN, Ross ZIRKLE
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Publication number: 20140105555Abstract: Radiation curable coatings for use as a Primary Coating for optical fibers, optical fibers coated with said coatings and processes to coat the optical fiber are described and claimed. The radiation curable coating is a radiation curable Primary Coating composition comprising: an oligomer; a first diluent monomer; a second diluent monomer, a photoinitiator; an antioxidant; and an adhesion promoter; wherein said oligomer is the reaction product of: a hydroxyethyl acrylate; an aromatic isocyanate; an aliphatic isocyanate; a polyol; a catalyst; and an inhibitor, and wherein said oligomer has a number average molecular weight of from at least about 4000 g/mol to less than or equal to about 15,000 g/mol; wherein a cured film of said radiation curable primary coating composition has a peak tan delta Tg of from about ?25° C. to about ?45° C. and a modulus of from about 0.50 MPa to about 1.2 MPa.Type: ApplicationFiled: December 13, 2013Publication date: April 17, 2014Applicant: DSM IP ASSETS B.V.Inventors: Xiaosong Dean WU, Steven R. SCHMID, Edward J MURPHY, John M ZIMMERMAN, Anthony Joseph TORTORELLO
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Patent number: 8697398Abstract: The invention relates to the field of recombinant DNA technology for the production of chondroitin, including the production of chondroitin sulfate via a combination of recombinant bacterial fermentation and post-fermentation sulfation.Type: GrantFiled: March 1, 2011Date of Patent: April 15, 2014Assignees: DSM IP Assets B.V., Seikagaku CorporationInventors: Daniel H. Doherty, Craig A. Weaver, Kentaro Miyamoto, Toshikazu Minamisawa
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Patent number: 8697364Abstract: The present invention provides a method for the transfection of filamentous fungal cells, comprising providing a multitude of containers, filling into each container an amount of polymer needed for the transfection, filling the cells to be transfected as well as an aqueous solution of transfection reagent into each of the containers, incubating the resulting mixture, removing the transfection reagent from the incubated mixture; and selecting the cells which have been transformed, characterized in that the total volume of the incubating mixture is less than 1 ml per container. Furthermore, the present invention provides the use of transformed filamentous fungal cells for the production of proteins or metabolites.Type: GrantFiled: June 25, 2007Date of Patent: April 15, 2014Assignee: DSM IP Assets B.V.Inventors: Marco Alexander Van Den Berg, Bianca Elisabeth Maria Gielesen, Adriana Marina Riemens
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Patent number: 8697170Abstract: The invention relates to a novel starch composition comprising: (a) amylomaltase-treated starch; (b) amylopectin starch; and (c) optionally, low DE maltodextrin. In addition, the invention relates to the use of the novel starch composition to produce a baked product, optionally thereby reducing the amount of fat needed for the recipe.Type: GrantFiled: July 29, 2009Date of Patent: April 15, 2014Assignee: DSM IP Assets B.V.Inventors: Pieter Lykle Buwalda, Vincentius Henrichus Johannes Melenhorst, José Mastenbroek
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Patent number: 8697126Abstract: The present invention describes a process for the manufacture of a solid composition comprising a microorganism, which process comprises a first step of blending and/or compacting the microorganism with a salt of a medium or long-chain fatty acid to prepare a powderous mixture or compacted granulate, and a second step of providing said powderous mixture or compacted granulate with a coating. The microorganisms are preferably probiotics. The invention also relates to the solid composition obtained by said process and to its use in food.Type: GrantFiled: May 18, 2006Date of Patent: April 15, 2014Assignee: DSM IP Assets B.V.Inventors: Chyi-Cheng Chen, Bruno H. Leuenberger, Loni Schweikert, Ernst Zedi
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Publication number: 20140100360Abstract: A process for producing a reaction product of a diazo compound, which process comprises: a. continuously supplying to a first reactor a precursor of a diazo compound; a water-miscible solvent; a base and water; b. mixing the precursor of a diazo compound; the water-miscible solvent; the base and water to generate a diazo compound; c. continuously removing from the first reactor, through a hydrophobic membrane, into a second reactor the formed diazo compound; d. continuously removing from the first reactor all reaction products that have not passed into the second reactor; e. continuously supplying to the second reactor a substrate in a non-water-miscible solvent; f. mixing the above components to generate a reaction product of a diazo compound; and g. continuously removing from the second reactor the non-water-miscible solvent and the reaction product of the diazo compound, and apparatus suitable for carrying out such a process.Type: ApplicationFiled: November 1, 2011Publication date: April 10, 2014Applicants: DSM FINE CHEMICALS AUSTRIA NFG. GMBH & CO KG, DSM IP ASSETS B.V.Inventors: Peter Poechlauer, Rafael Wilhelmus Elisabeth Ghislain Reintjens, Hubertus Johannes Adrianus Dielemans, Mehul Thathagar, Jeroen Hubertina Gerardus Konings
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Publication number: 20140099401Abstract: The present invention relates to newly identified asparaginase polypeptide variants of SEQ ID NO: 3 and to polynucleotide sequences that encode such novel asparaginase variants. Furthermore the invention relates to the use of these novel asparaginase variants in industrial processes.Type: ApplicationFiled: November 8, 2013Publication date: April 10, 2014Applicant: DSM IP ASSETS B.V.Inventors: Jan Metske VAN DER LAAN, Mark Cristiaan STOR, Ilse DE LANGE, Lisette MOHRMANN
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Publication number: 20140100380Abstract: The present invention relates to a process for obtaining lipid from a composition comprising cells and water, said process comprising contacting the composition with a desiccant, and recovering the lipid from the cells. The invention also relates to a lipid obtainable by this process. The process according to then invention enables lipid of high quality to be obtained with a high yield, and does not require a heating step.Type: ApplicationFiled: December 11, 2013Publication date: April 10, 2014Applicant: DSM IP ASSETS B.V.Inventors: Hendrik Louis BIJL, Daniel VERKOEIJEN, Heinz NIGGLI
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Publication number: 20140099063Abstract: Radiation curable coatings for use as a Primary Coating for optical fibers, optical fibers coated with said coatings and methods for the preparation of coated optical fibers. The radiation curable coating comprises at least one (meth)acrylate functional oligomer and a photoinitiator, wherein the urethane-(meth)acrylate oligomer CA/CR comprises (meth)acrylate groups, at least one polyol backbone and urethane groups, wherein about 15% or more of the urethane groups are derived from one or both of 2,4- and 2,6-toluene diisocyanate, wherein at least 15% of the urethane groups are derived from a cyclic or branched aliphatic isocyanate, and wherein said (meth)acrylate functional oligomer has a number average molecular weight of from at least about 4000 g/mol to less than or equal to about 15,000 g/mol; and wherein a cured film of the radiation curable Primary Coating composition has a modulus of less than or equal to about 1.2 MPa.Type: ApplicationFiled: December 12, 2013Publication date: April 10, 2014Applicant: DSM IP ASSETS B.V.Inventors: Paulus Antonius Maria STEEMAN, Xiaosong WU, Steven R. SCHMID, Edward J. MURPHY, John M. ZIMMERMAN, Anthony Joseph TORTORELLO
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Publication number: 20140098001Abstract: The invention relates to a geodesic radome comprising shaped panels containing a consolidated plurality of plies, the plies comprising polyolefin tapes, wherein the shaped panels have a compressive strength of between 10 MPa and 100 MPa, an interlaminar shear strength of between 3 MPa and 75 MPa and a thermal expansion of between 1e?6 1/K and 50e?6 1/K.Type: ApplicationFiled: March 5, 2012Publication date: April 10, 2014Applicant: DSM IP ASSETS B.V.Inventors: Eelco van Oosterbosch, Reimo Nickel, Chae Thompson, David Cunningham
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Patent number: 8691555Abstract: The present invention provides systems for producing engineered oleaginous yeast or fungi that express carotenoids.Type: GrantFiled: September 28, 2007Date of Patent: April 8, 2014Assignee: DSM IP Assests B.V.Inventors: Richard B. Bailey, Kevin T. Madden, Joshua Trueheart, Reed Doten, Maria Mayorga, Joshua Griffin Dunn, Dan Dueppen
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Publication number: 20140093459Abstract: Methods to to enhance solubility of butyl methoxydibenzoylmethane and/or bis-ethylhexyloxyphenol methoxyphenyl triazine in a cosmetic oil suitable as a solvent for butyl methoxydibenzoylmethane and/or bis-ethylhexyloxyphenol methoxyphenyl triazine are provided which include incorporating a solubility enhancing effective amount of a polyglycerol based UV filter in such cosmetic oil.Type: ApplicationFiled: December 3, 2013Publication date: April 3, 2014Applicant: DSM IP ASSETS B.V.Inventor: Alexander SCHLIFKE-POSCHALKO
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Patent number: 8685731Abstract: The invention relates to a process for the coloring of cells, preferably E1-immortalized HER cells, more preferably PER.C6 cells in a reactor in suspension in a cell culture medium, wherein the cells produce a biological substance, preferably an antibody, wherein at least one cell culture medium component is fed to the cell culture and wherein the cell culture comprising the cells, the biological substance and cell culture medium is circulated over a separation system and wherein the separation system separates the biological substance from substances having a lower molecular weight than the biological substance and wherein the biological substance is retained in or fed back into the reactor. Preferably part of the substances of lower molecular weight is continuously removed from the cell culture.Type: GrantFiled: December 6, 2012Date of Patent: April 1, 2014Assignee: DSM IP Assets B.V.Inventors: Gerben Meile Zijlstra, Robert Patrick Hoff, Jacob Schilder
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Patent number: 8685698Abstract: A yellow pigments generation deficient Sphingomonas strain (Sphingomonas sp. ZD001) and application thereof in preparing gellan gum by microbial fermentation are provided. The strain is preserved in China Center for Type Culture Collection (CCTCC) with the address of Wuhan University, Wuhan, 430072, China, the preservation date of the strain is 10 Sep. 2009, and the preservation serial number is CCTCC No: M 209298. The main beneficial effect of the present invention is that the fermented liquor contains no yellow pigments but is milky white, colorless superior gellan gum can be obtained by only depositing polysaccharide with a small quantity of ethanol or isopropanol, so that the post purification and de-coloration techniques of gellan gum production can be simplified, the yield can be enhanced, and the production cost can be reduced.Type: GrantFiled: August 13, 2010Date of Patent: April 1, 2014Assignees: Zhejiang University, Zhejiang DSM Zhongken Biotechnology Co., Ltd.Inventors: Xuechang Wu, Rongming Wu, Ou Li, Liang Zhu, Yamin Chen, Chaodong Qian, Mei Chen
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Patent number: 8685456Abstract: The present invention is directed to topical compositions, comprising isoflavone nanoparticle compositions. The isoflavone nanoparticle compositions contain isoflavone in the form of nanoparticles and preferably a carrier. In the topical compositions recrystallization of the isoflavone to bigger particles is avoided.Type: GrantFiled: January 31, 2006Date of Patent: April 1, 2014Assignee: DSM IP Assets B.V.Inventors: Raphael Beumer, Chyi-Cheng Chen, Heinz Gutzwiller, Philippe Emmanuel Maillan, Markus Nowotny, Bernd Schlegel, Juergen H. Vollhardt
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Patent number: 8685683Abstract: The present invention relates to newly identified genes that encode proteins that are involved in the synthesis of L-ascorbic acid (hereinafter also referred to as Vitamin C) and/or 2-keto-L-gulonic acid (hereinafter also referred to as 2-KGA). The invention also features polynucleotides comprising the full-length polynucleotide sequences of the novel genes and fragments thereof, the novel polypeptides encoded by the polynucleotides and fragments thereof, as well as their functional equivalents. The present invention also relates to the use of said polynucleotides and polypeptides as biotechno logical tools in the production of Vitamin C and/or 2-KGA from microorganisms, whereby a modification of said polynucleotides and/or encoded polypeptides has a direct or indirect impact on yield, production, and/or efficiency of production of the fermentation product in said microorganism.Type: GrantFiled: January 9, 2009Date of Patent: April 1, 2014Assignee: DSM IP Assets B.V.Inventors: Bastien Chevreux, Nigel John Mouncey
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Patent number: 8685949Abstract: The present invention relates to the use of 25-hydroxy-vitamin D3 to improve the general health status of female animals at least during gestation and/or lactation. The invention also relates to the use of 25-hydroxy-vitamin D3 in animal breeding. More particular, the invention relates to the use of 25-hydroxy-vitamin D3 for improving litter size and vitality of piglets in pig breeding and for providing better body frame and increasing gestation backfat gain, reducing lactation backfat loss and increasing lactation feed intake of sows and gilts.Type: GrantFiled: November 23, 2006Date of Patent: April 1, 2014Assignee: DSM IP Assets B.V.Inventors: Thau Kiong Chung, Francisco Feranil Penalba, Gilbert Weber