Patents Assigned to DSM
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Patent number: 8772230Abstract: This invention relates to the use of niacin and/or trigonelline compounds to increase muscle weight during periods of activity or to inhibit muscle loss during periods of inactivity.Type: GrantFiled: June 10, 2010Date of Patent: July 8, 2014Assignee: DSM IP Assets B.V.Inventors: Angelika Friedel, Karin Kuratli, Christof Wehrli, Karin Wertz, Swen Wolfram, Ying Wang-Schmidt
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Patent number: 8772397Abstract: Non-fibrous-reinforced thermoplastic moulding compositions comprising a metal powder as a heat stabilizer are provided. The metal powder has a weight average particle size (dm) of at most 1 mm and the metal in the metal powder is selected from the group consisting of elementary metals from Group VB, VIB, VIIB and VIIIB of the Periodic Table, and mixtures thereof. A thermoplastic polyamide is also provided with an Mw of at most 50,000 g/mol, or a blend of at least two thermoplastic polymers with Tmelt or Tg differing by at least 20° C., or a second thermostabilizer. The invention also relates to the use of these compositions in high temperature applications.Type: GrantFiled: January 9, 2006Date of Patent: July 8, 2014Assignee: DSM IP Assets B.V.Inventors: Pieter Gijsman, Wilhelmus J. M. Sour, Rudy Rulkens, Robert H. C. Janssen
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Patent number: 8772373Abstract: A process for producing a coating composition includes separately chemically grafting particles with compounds having reactive groups and compounds having hydrophilic polymer chains. The hydrophilic polymer chains dissolve in water at least one temperature between 0 and 100° C. The reactive groups may react with the substrate and or react with one another to form a cross-linked coating, comprising the particles. A process for forming a coating on a substrate is also provided.Type: GrantFiled: September 10, 2013Date of Patent: July 8, 2014Assignee: DSM IP Assets B.V.Inventors: Edwin Currie, Jens Thies, Paul Holmes
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Publication number: 20140186118Abstract: The invention relates to a barrier system comprising a barrier wall for stopping a flow of a substance to one side of said wall, wherein said barrier wall comprises a fabric impervious to the flow of said substance and containing high strength polyolefin fibers.Type: ApplicationFiled: April 10, 2012Publication date: July 3, 2014Applicant: DSM IP ASSETS B.V.Inventors: Roelof Marissen, Dietrich Wienke
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Publication number: 20140187709Abstract: The invention relates to a polyamide composition with an improved resistance against yellowing. The invention also relates to a shaped article made from the composition and to a method of forming such a shaped article. The polyamide composition comprises: a. 90 to 40 wt % of one or more semi-aromatic polyamides and b.10 to 60 wt % of one or more of aliphatic polyamides and c.1 at least one white pigment as secondary component and c.2 optionally one or more other secondary components, wherein the sum of the amount of semi-aromatic and aliphatic polyamide is 100 wt % and wherein: i. the semi-aromatic polyamide is derived from one or more aliphatic diamine monomers containing 4 to 12 carbon atoms and one or more benzene dicarboxylic acid monomers and ii.Type: ApplicationFiled: May 30, 2012Publication date: July 3, 2014Applicant: DSM IP ASSETS B.V.Inventors: Hans Klaas Van Dijk, Konraad Dullaert
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Publication number: 20140186503Abstract: Disclosed are food articles comprising microcapsules as delivery devices. Methods of preparing such food articles are also disclosed.Type: ApplicationFiled: March 5, 2014Publication date: July 3, 2014Applicant: DSM Nutritional ProductsInventors: Peter H. Mattson, Richard A. Gorski, Brenda Y. Fong, Laura M. Tringale, Deepa Mathew, Peter C. Dea, Sharon Ann Spurvey, Suzelle Rejeanne Robert, Michelle M. Boyden
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Publication number: 20140187749Abstract: The present invention relates to a method for the purification of antibodies from a protein mixture produced in a bioreactor, at least comprising the steps of intermediate purification and polishing, wherein the intermediate and polishing step comprises in-line anion exchange chromatography (AEX) treatment and mixed mode chromatography (MiMo) treatment in flow through mode. The present invention further relates to a single operational unit comprising both an anion exchange chromatography part and a mixed mode chromatography part, which are serially connected, wherein the unit comprises an inlet at the upstream end of the anion exchange chromatography part and an outlet at the downstream end of the mixed mode chromatography part and wherein the unit also comprises an inlet between the anion exchange chromatography part and the mixed mode chromatography part.Type: ApplicationFiled: June 8, 2012Publication date: July 3, 2014Applicant: DSM IP ASSETS B.V.Inventors: Maria Perlasca Islas, Diderik Reinder Kremer, Mark K. Doeven, Henderik E. Veenstra
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Publication number: 20140186494Abstract: The present invention relates to novel lipase polynucleotide sequences, their corresponding proteins as well as ways of manufacturing said sequences and said proteins and use of the proteins in the preparation of food compositions. The invention further relates to methods for releasing proteins from the exterior of a host cell as well as to a method for killing micro-organisms.Type: ApplicationFiled: January 30, 2014Publication date: July 3, 2014Applicant: DSM IP ASSETS B.V.Inventors: Lucie PARENICOVA, Ronald BUSINK, JAN Metske VAN DER LAAN
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Patent number: 8765422Abstract: Disclosed are methods and compositions related to ONC-T18, D4-desaturases, D5 elongases, their isolation, characterization, production, identification, and use for fatty acid production, as well as organisms containing these compositions and organisms expressing them.Type: GrantFiled: October 31, 2007Date of Patent: July 1, 2014Assignee: DSM Nutritional Products AGInventors: Adam Burja, Gabrielle S. Chafe, Helia Radianingtyas
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Patent number: 8765186Abstract: The present invention relates to a process for the manufacture of an emulsion or dispersion containing one or more carotenoids, in a preferred embodiment it relates to the manufacture of a powder containing one or more carotenoids, furthermore to the powder obtainable by said process and a food composition, especially a beverage, containing said powder.Type: GrantFiled: March 4, 2008Date of Patent: July 1, 2014Assignee: DSM IP Assets B.V.Inventors: Christian Schäfer, David Schaffner
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Patent number: 8765967Abstract: The invention provides a process for producing microcapsules with UV filter activity, wherein at least one type of crosslinkable chromophore with UV-A and/or UV-B and/or UV-C filter activity and optionally at least one type of crosslinkable monomer which does not have UV-A and/or UV-B and/or UV-C filter activity are subjected to a crosslinking reaction in the absence of non-crosslinkable chromophores with UV-A and/or UV-B and/or UV-C filter activity and microcapsules obtainable by this process.Type: GrantFiled: August 2, 2011Date of Patent: July 1, 2014Assignee: DSM IP Assets B.V.Inventor: Katja Berg-Schultz
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Publication number: 20140178318Abstract: Methods of making polyglycerol based UV-filters, topical compositions comprising such polyglycerol based UV-filters and the use of such novel polyglycerol based UV-filters to enhance the solubility of butyl methoxydibenzoylmethane or bis-ethylhexyloxyphenol methoxyphenyl triazine in cosmetic oils are provided.Type: ApplicationFiled: February 26, 2014Publication date: June 26, 2014Applicant: DSM IP ASSETS B.V.Inventors: Anne JANSSEN, Christine MENDROK-EDINGER, Alexander SCHLIFKE-POSCHALKO
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Publication number: 20140178949Abstract: The present invention relates to a method for preparing an adipate ester or thioester. The invention further relates to a method for preparing adipic acid from said ester or thioester. Further the invention provides a number of methods for preparing an intermediate for said ester or thioester. Further the invention relates to a method for preparing 6-amino caproic acid (6-ACA), a method for preparing 5-formyl valeric acid (5-FVA), and a method for preparing caprolactam. Further, the invention relates to a host cell for use in a method according to the invention.Type: ApplicationFiled: November 15, 2013Publication date: June 26, 2014Applicant: DSM IP ASSETS B.V.Inventors: LIANG WU, AXEL CHRISTOPH TREFZER, STEFAAN MARIE ANDRE DE WILDEMAN, MARCO ALEXANDER VAN DEN BERG
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Publication number: 20140178932Abstract: The present invention provides a method for the transfection of filamentous fungal cells, comprising providing a multitude of containers, filling into each container an amount of polymer needed for the transfection, filling the cells to be transfected as well as an aqueous solution of transfection reagent into each of the containers, incubating the resulting mixture, removing the transfection reagent from the incubated mixture; and selecting the cells which have been transformed, characterized in that the total volume of the incubating mixture is less than 1 ml per container. Furthermore, the present invention provides the use of transformed filamentous fungal cells for the production of proteins or metabolites.Type: ApplicationFiled: February 27, 2014Publication date: June 26, 2014Applicant: DSM IP ASSETS B.V.Inventors: Marco Alexander Van Den Berg, Bianca Elisabeth Maria Gielesen, Adriana Marina Riemens
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Publication number: 20140179802Abstract: The present invention relates to a fiber comprising a biodegradable polymer which undergoes dimensional change upon injection in the human or animal body wherein the dimensional change is a reduction of the surface area to volume ratio of a factor 2 to 10. The fiber is sized for injection via a pharmaceutical syringe needle having a bore of at least 25 Gauge. The biodegradable polymer is an amorphous biodegradable polymer selected from the group of poly-hexamethylene carbonates or polyesteramides. The amorphous biodegradable polymer is a preferably a polyesteramide comprising alpha-amino acids, diols and dicarboxylic acids as building blocks. The invention further relates to the use of the fiber for the manufacturing of a medicament for the treatment of ophthalmic diseases. The invention also relates to a process for the manufacturing of the fiber comprising the following process steps; a. extruding a biodegradable polymer into a fiber fitting in a needle of at least 25 Gauge b.Type: ApplicationFiled: May 2, 2012Publication date: June 26, 2014Applicant: DSM IP ASSETS B.V.Inventors: Astrid Franken, George Mihov, Jens Christoph Thies
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Publication number: 20140174822Abstract: A waterproof seal for electrical assemblies having conductive wires attached to a metal contact and inserted into a connector body. The conductive wires and metal contact are coated with solder to fill the gaps. The space between the soldered wires and the connector body are filled with an epoxy. The wire insulation and connector body are continuously sealed with a bonding agent. A section of wire insulation and the connector body are encased within an outer plastic jacket overmold.Type: ApplicationFiled: December 9, 2013Publication date: June 26, 2014Applicant: DSM&T Company, Inc.Inventor: Sergio Corona
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Publication number: 20140180221Abstract: The invention relates to an article comprising a coating, which coating comprises at least two layers, of which the inner layer is a primer layer, comprising a supporting network comprising a supporting polymer, and the outer layer is a functional layer comprising a multifunctional polymerizable compound.Type: ApplicationFiled: December 13, 2013Publication date: June 26, 2014Applicant: DSM IP ASSETS B.V.Inventors: Aylvin Jorge Angelo Athanasius DIAS, Edith Elisabeth M. VAN DEN BOSCH, Peter BRUIN, Marnix ROOIJMANS, Rudolfus Antonius Theodorus Maria VAN BENTHEM
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Patent number: 8759405Abstract: Methods of enhancing the appearance of a mammal's hair/fur are provided by the administration of an oral nutraceutical or food composition comprising steviol or a steviol precursor, without chromene, for a time sufficient and in an amount effective to enhance the overall appearance of the mammal's hair/fur. The enhancement of the appearance of the mammal's hair/fur includes restoring hair/fur color, lessening hair loss, increasing the thickness of hair, counteracting age-associated hair thinning, and delaying the onset or severity of age-associated hair loss and thinning. A nutraceutical or food which includes steviol or a steviol precursor in an amount sufficient to enhance the overall appearance of a mammal's hair/fur is also provided.Type: GrantFiled: July 20, 2010Date of Patent: June 24, 2014Assignee: DSM IP Assets B.V.Inventors: Regina Goralczyk, Annis O. Mayne-Mechan, Jenny Piussi, Henry Rieger, Hasan Mohajeri
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Patent number: 8759024Abstract: The invention relates to processes and means for the biotechnologically fermentative production of riboflavin (hereinafter also referred to as vitamin B2) and means for the implementation of this process, in particular a modified microbial host cell with increased riboflavin yield. The invention thus provides new processes and means for the regulation of the expression of enzyme activities involved in the riboflavin production of the host cell.Type: GrantFiled: December 15, 2009Date of Patent: June 24, 2014Assignee: DSM IP Assets B.V.Inventors: Florian Kirchner, Klaus Mauch, Joachim Schmid
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Publication number: 20140170428Abstract: An aqueous, metal, coating composition (and process for obtaining it) comprising a block copolymer and a polymer P; wherein the block copolymer comprises at least blocks [A]x[B]y, where at least block [A] is obtained by a controlled radical polymerisation of at least one ethylenically unsaturated monomer via a reversible addition-fragmentation chain transfer (RAFT) mechanism in solution in the presence of a control agent and a source of free radicals; and where (a) block [A] comprises (i) 0 to 80 mol % of metal adhering ethylenically unsaturated monomers; (ii) 0 to 100 mol % of water dispersible ethylenically unsaturated monomers; (iii) 0 to 70 mol % of C1 to C30 hydrocarbo (meth)acrylate and/or styrenic monomers; (iv) 0 to 35 mol % of ethylenically unsaturated monomer different from i), ii)+iii); where the amount of at least one of i), ii), iii)+iv) is >0 mol %; block [A] has a Hansch parameter <1.Type: ApplicationFiled: February 24, 2014Publication date: June 19, 2014Applicant: DSM IP ASSETS B.V.Inventors: Michael Arnoldus Jacobus SCHELLEKENS, Tijs NABUURS, John GEURTS, Gerardus Cornelis OVERBEEK