Patents Assigned to Ecole Polytechnique
  • Patent number: 11413459
    Abstract: The present invention relates to systems and methods for planning and/or providing neurostimulation for a patient. An example system includes a pathological spinal cord map storage module for storing at least one pathological spinal cord map describing activation of a spinal cord of a patient, a healthy spinal cord map storage module for storing at least one reference map describing physiological activation of the spinal cord of at least one healthy subject, an analysis module for generating a deviation map, the deviation map describing an activation difference between the pathological spinal cord map and the reference map, and a compensation module for calculating, based on the deviation map, a neurostimulation protocol for compensating the activation difference.
    Type: Grant
    Filed: November 29, 2018
    Date of Patent: August 16, 2022
    Assignees: ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL), ONWARD MEDICAL B.V.
    Inventors: Flavio Raschella, Silvestro Misera, Gregoire Courtine, Tomislav Milekovic, Fabien Wagner, Marco Capogrosso, Jurriaan Bakker, Robin Brouns, Vincent Delattre
  • Patent number: 11401463
    Abstract: The present invention concerns a luminescent particle comprising a nanoparticle of formula A1-xLnxVO4(1-y)(PO4)y??(I) in which A is selected from yttrium (Y), gadolinium (Gd), lanthanum (La), and mixtures thereof; Ln is selected from europium (Eu), dysprosium (Dy), samarium (Sm), neodymium (Nd), erbium (Er), ytterbium (Yb), and mixtures thereof; 0<x<1; and 0?y<1; characterized in that the nanoparticle on its surface has tetraalkylammonium cations in an amount such that said nanoparticle has a zeta potential, ?, of less than or equal to ?28 mV in an aqueous medium with a pH?5, more particularly with a pH?5.5, and with an ionic conductivity >100 ?S·cm?1. It also concerns a method for preparing such luminescent particles, a colloidal suspension of these particles, and the use thereof as a diagnostic agent, and also a diagnostic kit comprising such luminescent particles.
    Type: Grant
    Filed: May 18, 2018
    Date of Patent: August 2, 2022
    Assignees: ECOLE POLYTECHNIQUE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
    Inventors: Thierry Gacoin, Maximilian Richly, Pascal Preira, Antigoni Alexandrou, Cédric Bouzigues, Rabei Mohammedi
  • Patent number: 11401625
    Abstract: The invention relates to a method for making nanopores in thin layers or monolayers of transition metal dichalcogenides that enables accurate and controllable formation of pore within those thin layer(s) with sub-nanometer precision.
    Type: Grant
    Filed: February 11, 2021
    Date of Patent: August 2, 2022
    Assignees: Ecole Polytechnique Federale De Lausanne (EPFL), Roche Sequencing Solutions, Inc.
    Inventors: Jiandong Feng, Ke Liu, Aleksandra Radenovic, Yann Astier
  • Publication number: 20220228340
    Abstract: The present invention relates to a method for inducing ground consolidation. The method comprises providing a first chamber in a first hole in the ground, and a second chamber in a second hole in the ground, the first and second chambers being liquid-impermeable and electrically conductive; providing a first electrolytic fluid in the first chamber and a second electrolytic fluid in the second chamber; placing at least a first electrode in the first chamber, and at least a second electrode in the second chamber, the first and second electrodes being operatively connected to a power supply; feeding consolidation fluids into the ground for feeding reactants of a consolidation process, and catalysers for the reactants into the ground; and applying to the first and second electrodes an electric current.
    Type: Application
    Filed: May 31, 2019
    Publication date: July 21, 2022
    Applicant: ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL)
    Inventors: Dimitrios TERZIS, Lyesse LALOUI, Patrick HICHER
  • Patent number: 11389096
    Abstract: An on-body wearable bio-fluid collection and sensing device including an interface or interface surface comprising at least one biocompatible material for contacting a bodily part; at least one inlet for receiving the bio-fluid, at least one outlet for evacuating the bio-fluid, a plurality of semiconductor sensors configured to analyze the received bio-fluid, at least one reference electrode for biasing a bio-fluid gate of at least one of the semiconductor sensors, and at least one micro-fluidic or nano-fluidic channel in fluid communication with the at least one inlet, the at least one outlet and the at least one reference electrode; the at least one micro-fluidic or nano-fluidic channel includes the plurality of semiconductor sensors.
    Type: Grant
    Filed: March 9, 2017
    Date of Patent: July 19, 2022
    Assignee: ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL)
    Inventors: Mihai Adrian Ionescu, Hoël Guerin, Erick García Cordero, Francesco Bellando
  • Patent number: 11385719
    Abstract: The present disclosure relates to a device including electrostatic brakes providing haptic kinaesthetic feedback to a user in e.g. assistive, rehabilitation or virtual reality scenarios, as well as tele-manipulation.
    Type: Grant
    Filed: July 10, 2018
    Date of Patent: July 12, 2022
    Assignee: ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL)
    Inventors: Ronan Hinchet, Herbert Shea
  • Publication number: 20220206275
    Abstract: A light microscope has a light source for illuminating a specimen, a sensor array comprised of photon-counting detector elements for measuring detection light coming from the specimen, and a control device for controlling the sensor array. The control device is configured for flexibly binning the photon-counting detector elements into one or more super-pixels.
    Type: Application
    Filed: April 9, 2019
    Publication date: June 30, 2022
    Applicants: Carl Zeiss Microscopy GmbH, Ecole Polytechnique Federale de Lausanne
    Inventors: Tiemo ANHUT, Daniel SCHWEDT, Ivan Michel ANTOLOVIC, Claudio BRUSCHINI, Edoardo CHARBON
  • Publication number: 20220207864
    Abstract: A method of classifying a media includes receiving a media file and extracting therefrom first and second data streams including first and second media content, respectively, the media content being associated with the media item. First and second feature vectors describing the first and second media content, respectively, are generated. At least a first single feature vector representing the first sequence of first feature vectors and the second sequence of second feature vectors is generated, or at least a first single feature vector representing at least the first sequence of first feature vectors is generated. A second feature vector representing at least the second sequence of second feature vectors is generated. A probability vector from the first single feature vector, or from the first and second single feature vectors is generated. A user profile suitability class is assigned to the media item based on the probability vector.
    Type: Application
    Filed: April 29, 2019
    Publication date: June 30, 2022
    Applicant: ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL)
    Inventors: Gabriel AUTÈS, Sami ARPA, Sabine SÜSSTRUNK
  • Patent number: 11372481
    Abstract: A dielectric actuator including an enclosure forming a cavity having a dielectric fluid therein, the enclosure having a base, a flexible membrane and a reversibly-stretchable membrane, and a pair of electrodes, one electrode of the pair of electrodes arranged at the flexible membrane, the other electrode arranged at the base, the pair of electrodes arranged to generate an electric field to an area of the cavity that is filled with the dielectric fluid, wherein when the electric field is generated between the pair of electrodes, an electrostatic pressure in the dielectric fluid causes the flexible membrane to move towards the base, reducing an initial volume of the area of the cavity, increases a pressure of the dielectric fluid inside the cavity, and causes the reversibly-stretchable membrane to bump out to an expanded state.
    Type: Grant
    Filed: April 14, 2020
    Date of Patent: June 28, 2022
    Assignee: ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL)
    Inventors: Edouard Leroy, Herbert Shea, Min Gao
  • Publication number: 20220195489
    Abstract: Motion detector comprising a flexible support (1,5) adapted to hold at least one object (6-9), a sensor (4) for measuring the displacement of said support (1) and processing means for differentiating the fluctuations of said support (1) from those induced by said object (6-9).
    Type: Application
    Filed: March 14, 2022
    Publication date: June 23, 2022
    Applicant: ECOLE POLYTECHNIQUE FÉDÉRALE DE LAUSANNE (EPFL)
    Inventors: Sandor KASAS, Giovanni Longo, Giovanni Dietler, Livan Bladimir Alonso Sarduy
  • Patent number: 11364320
    Abstract: A radiopaque composition with low viscosity and increased photopolymerizability for application or filling of hollow structures is disclosed. Moreover, a method to apply and monitor the application and/or the photopolymerization of the composition are presented.
    Type: Grant
    Filed: July 7, 2017
    Date of Patent: June 21, 2022
    Assignee: Ecole Polytechnique Federale de Lausanne (EPFL)
    Inventor: Andreas Schmocker
  • Publication number: 20220178588
    Abstract: The invention provides in one embodiment a heat exchanger module (1) comprising a) a flexible support (100); b) at least one tubular member (200) having its main axis substantially parallel with the plane of the flexible support (100); c) a conductive flexible matrix (300) embedding the at least one tubular member (200); and d) a flexible case (400) enwrapping the flexible support (100), the at least one tubular member (200) and the conductive flexible matrix (300). A coating for a built environment comprising a plurality of heat exchanger modules (1) can be implemented, as well as a system further including pumping means (600). The invention also foresees a method for providing heat exchange processes between the heat exchanger module (1), the coating or the system of the invention and a built environment.
    Type: Application
    Filed: March 26, 2020
    Publication date: June 9, 2022
    Applicant: ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL)
    Inventors: Lyesse LALOUI, Alessandro ROTTA LORIA
  • Patent number: 11355720
    Abstract: The present invention relates to a method for producing a solid state solar cell, including the steps of providing a conductive support layer or current collector, applying a metal oxide layer on the conducting support layer, applying at least one sensitizer layer onto the metal oxide layer or onto a first optional layer covering the metal oxide layer, the first optional layer including a charge transporting layer, applying a second optional layer onto the sensitizer layer, the second optional layer being selected from a charge transporting layer, a protective layer, or a combination of both layers, and providing a counter electrode or a metal electrode onto the sensitizer layer or the second optional layer. The at least one sensitizer layer includes an organic-inorganic or metal halide perovskite and is treated by the application of a vacuum before the annealing of the sensitizer.
    Type: Grant
    Filed: March 16, 2017
    Date of Patent: June 7, 2022
    Assignee: Ecole Polytechnique Federale de Lausanne (EPFL)
    Inventors: Xiong Li, Chenyi Yi, Dongqin Bi, Shaik Mohammed Zakeeruddin, Michael Graetzel, Anders Hagfeldt
  • Patent number: 11351810
    Abstract: The present invention proposes a method for producing an authenticable moiré shape that simultaneously moves and shows a beating effect. The method relies on a combination of the 1D or the 2D moiré and the level line moiré. When tilting a compound showing such a moiré, the moiré shape moves, its intensity levels change significantly but its shape remains the same and is recognizable. Embodiments comprise a base layer made of patterned metallic tiny shapes and a revealing layer made of a 1D array of cylindrical lenslets or of a 2D array of spherical or aspherical lenslets.
    Type: Grant
    Filed: September 10, 2020
    Date of Patent: June 7, 2022
    Assignee: Ecole Polytechnique Fédérale de Lausanne (EPFL)
    Inventors: Thomas Walger, Roger D. Hersch, Jürgen Brugger
  • Publication number: 20220170920
    Abstract: One embodiment of the present invention concerns a biosensor for sensing stress hormone cortisol concentration in a biofluid. The biosensor comprises: an electrical transistor transducer comprising a transistor gate electrode; a sensing electrode element comprising a metal element having a biofluid facing surface, and a graphene layer on the biofluid facing surface of the metal element, the sensing electrode element being connected to the transistor gate electrode by an electrical connector to form an extended gate configuration with the transistor gate electrode; and a reference electrode configured to be in contact with the biofluid, and configured to electrically bias the transistor gate electrode through the biofluid. The sensing electrode element is functionalised by at least a layer of aptamers placed indirectly or directly on the graphene layer, and configured to catch cortisol hormones in the biofluid to thereby change a surface potential of the sensing electrode element.
    Type: Application
    Filed: December 1, 2021
    Publication date: June 2, 2022
    Applicant: ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL)
    Inventors: Mihai Adrian IONESCU, Sheibani SHOKOOFEH
  • Patent number: 11331009
    Abstract: Presented herein are devices for collecting and/or channeling a biofluid (e.g., sweat, tears, saliva) and detecting and/or quantifying one or more biomarkers in the biofluid. The one or more biomarkers may include, for example, ions, salts thereof, hormones and/or steroids, proteins, metabolites and organic compounds. In certain embodiments, the devices described herein include a specially designed interface and a zero-energy micro pump that allow the device to be comfortably affixed directly to the skin of a user while biofluid is efficiently and non-invasively collected from the skin of the user. In certain embodiments, the biofluid collection and sensing device is housed on or in another wearable device, such as a wrist band or a smart watch. In certain embodiments, the devices described herein are disposable (e.g., after a certain period of use and/or wear the device can be disposed and replaced with a low-cost replacement).
    Type: Grant
    Filed: March 6, 2018
    Date of Patent: May 17, 2022
    Assignees: Xsensio SA, ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL)
    Inventors: Mihai Adrian Ionescu, Johan Frédéric Longo, Fabien Patrick Wildhaber, Hoël Maxime Guérin, Francesco Bellando, Erick García Cordero
  • Patent number: 11333776
    Abstract: A system for characterising a beam of charged particles. The system includes a stack comprising an ultra-thin pattern formed from an electrically conductive material; a thin substrate bearing the pattern. The stack forms an emitting electrode able to emit secondary electrons in proximity to a surface of the pattern when the emitting electrode is passed through by the beam of charged particles.
    Type: Grant
    Filed: February 5, 2019
    Date of Patent: May 17, 2022
    Assignees: ECOLE POLYTECHNIQUE, CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE
    Inventors: Denis Bernard, Bruno Boyer, Pascal Manigot, Christophe Thiebaux, Marc Verderi
  • Patent number: 11329229
    Abstract: The present invention relates to a compound of formula (I) based on enamine derivatives and used as organic hole conductors or hole transporting material in an optoelectronic or photoelectrochemical device. The present invention relates to the hole transporting compounds based on enamine derivatives for efficiency perovskite or dye sensitized solar cells and optoelectronic devices, organic light-emitting diode (OLED), field-effect transistors (FET).
    Type: Grant
    Filed: September 15, 2017
    Date of Patent: May 10, 2022
    Assignees: KAUNO TECHNOLOGIES UNIVERSITETAS, ECOLE POLYTECHNIQUE FEDERALE DE LAUSAANE (EPFL)
    Inventors: Vytautas Getautis, Maryte Daskeviciene, Tadas Malinauskas, Mohammad Khaja Nazeeruddin, Sanghyun Paek, Kasparas Rakstys
  • Publication number: 20220127310
    Abstract: Aerolysin polypeptides and/or mutant aerolysin monomers include modified amino acid sequences that could have improved substrate analyte, such as (poly)nucleotide and peptide, improved reading properties such as enhanced substrate analyte capture and improved substrate analyte recognition and/or discrimination. Also, aerolysin pores may be derived from the mutant monomers as well as apparatuses and devices may include modified aerolysin polypeptides. Further, methods of using modified aerolysin proteins and pores derive therefrom may be used in characterizing and/or sequencing a polymeric molecule or may be for use as molecular sensors.
    Type: Application
    Filed: October 28, 2020
    Publication date: April 28, 2022
    Applicant: ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL)
    Inventors: Matteo DAL PERARO, Chan CAO
  • Patent number: 11309896
    Abstract: A reconfigurable logic circuit comprises first, second and third switching circuits arranged for receiving first, second and third input bits, respectively, and each arranged for being configured in a mode wherein the corresponding input bit is passed on or in a mode; a first exclusive OR logic block operable on the outputs of the first, second and third switching circuits and arranged to output a sum bit; fourth, fifth and sixth switching circuits arranged for receiving a fourth, fifth and sixth input bits and arranged for being configured in a mode; first, second and third AND logic blocks, each arranged for receiving a different pair of the outputs of certain switching circuits; a second exclusive OR logic block operable on the outputs of certain AND logic blocks and arranged to produce a carry output bit.
    Type: Grant
    Filed: November 19, 2018
    Date of Patent: April 19, 2022
    Assignees: KATHOLIEKE UNIVERSITEIT LEUVEN, UNIVERSITÀ DELLA SVIZZERA ITALIANA, ECOLE POLYTECHNIQUE FÉDÉRALE DE LAUSANNE (EPFL)
    Inventors: Nele Mentens, Francesco Regazzoni, Edoardo Charbon