Abstract: Peptides that specifically bind erythrocytes are described. These are provided as peptidic ligands having sequences that specifically bind, or as antibodies or fragments thereof that provide specific binding, to erythrocytes. The peptides may be prepared as molecular fusions with therapeutic agents, tolerizing antigens, or targeting peptides. Immunotolerance may be created by use of the fusions and choice of an antigen on a substance for which tolerance is desired.

Abstract: A recommender system for determining multimedia items to be presented in an online interface of a multimedia content provider. The recommender system continuously observes the user's behavior in order to define a context for the user which on the basis of which recommendations are computed. The recommender system observes a variety of events so as to improve the level of pertinence of the recommendations which are presented to the user in the online interface. The recommender system further observes the collection of multimedia items which are hosted by an online multimedia content provider system.

Abstract: A method for chemically passivating a surface of a product made of a III-V semiconductor material in which a) a P(N) polymer film is formed by deposition in a solvent comprising liquid ammonia. The film is formed by deposition, without electrochemical assistance, in the solvent, in the presence of an oxidizing chemical additive comprising phosphorous and generating electrical charge carriers in said surface.

Abstract: The invention relates to a method for generating a focused charged-particle beam, comprising at least the steps of: a) generating a charged-particle beam (10); b) emitting a laser pulse (40); c) generating a focusing magnetic field structure in a target (50) by means of an interaction between the laser pulse and the target; and d) making the charged-particle beam penetrate the focusing magnetic field structure at least partially.

Abstract: A single field effect transistor capacitor-less memory device, and method of operating the same, including a drain region, a source region, an intrinsic channel region between the drain region and the source region forming the single field effect transistor and a base. The device further includes a fin structure comprising the source region, the intrinsic channel and the drain region, the fin structure extending outwardly from the base, and a double gate comprising a first gate connected to a first exposed lateral face of the intrinsic channel region for transistor control, and a second gate connected to a second exposed lateral face of the intrinsic channel region to generate a potential well for storing mobile charge carriers permitting memory operation, the first gate and the second gate being asymmetric for asymmetric electrostatic control of the device.

Abstract: A system for the treatment of Alzheimer's disease is provided by moving cerebrospinal fluid containing particles know to contribute to onset of Alzheimer's disease from a source of cerebrospinal fluid to the stomach or bladder, where the particles are safely digested by gastric acid or excreted, the system including an implantable pump, an inlet catheter, an outlet catheter, and a one-way valve. The system further includes at least one filter to filter harmful particles from the cerebrospinal fluid and return the filtered cerebrospinal fluid back to the source of cerebrospinal fluid, where the harmful particles blocked by the filter may be rinsed off the filter and transported to the stomach or bladder.

Abstract: We propose new methods for creating color or achromatic images that are printed with classical cyan, magenta, yellow and a white diffusing ink on a metallic substrate. We optimize the surface coverages of the cyan, magenta, yellow and white inks in order to create color prints on a metallic surface that look bright and colorful under specular reflection and also look good under non-specular observation conditions. We also provide new means for the prevention of counterfeits. A first effect enables viewing on the same metallic print one achromatic image in specular viewing mode and a second independent achromatic image in non-specular viewing mode. The second effect enables hiding a pattern such as text, graphics or a grayscale image within the printed color image in one viewing mode, specular or non-specular and showing that pattern in the second viewing mode, non-specular or specular, respectively.

Abstract: The invention substantially relates to an imaging system for the chemical, biological or biochemical analysis of a sample (10), comprising a device (40) for holding the sample (10), a device (20) for optical detection, a lighting device (30), liable to emit a monochromatic light beam, and a wide aperture objective (f1), It is substantially characterized in that the objective (f1) is configured for, downstream of the sample (10): focusing the excitation light beam reflected at a point (C) located in the focal plane (FF) of said objective (f1), and transforming the retransmitted or scattered light beam into a quasi-parallel beam, and in that the system further comprises a device (70) for selectively blocking the collected light beam by said objective (f1).

Abstract: The present invention relates to compounds of formula (I) based on a porphyrin core and a ?-conjugated linker or acceptor introduced between the porphyrin core and an anchoring group having a high absorption coefficient covering the whole UV-Visible and near-infrared spectral response, and their use as sensitizer or dye and an electrochemical or optoelectronic device including a compound of the invention.

Abstract: A method for the preparation of a hyperpolarized solution of molecules comprises the steps: 1) suspending or coating of a micro-particulate matrix, which is comprising or consisting of the molecules, with a glass-forming solution or suspension comprising a DNP-suitable polarizing agent at a first temperature at which the micro-particulate matrix is not dissolving; 2) lowering the temperature leading to a frozen glassy DNP sample; 3) transferring the electron spin polarization of the polarizing agent in the glassy sample in a magnetic field to abundant nuclear spins of the glass-forming solution or suspension and/or the polarizing agent as well as to abundant nuclear spins of the molecules and cross-polarization from the abundant nuclear spins in the molecules to one different nuclear spin type in the molecules; and 4) increasing the temperature and dissolving the molecules which are hyperpolarized with respect of the different nuclear spins.

Abstract: A method for classification of ECG beats into normal and different categories of abnormal beats. The method comprises the following steps, performed on a computing platform: a. performing a training phase comprising taking as an input one or more ECG beats that are pre-classified into the different categories, with each ECG beat decomposed into multiple features and defining membership functions for each beat category for each feature; b.

Abstract: A time reversal process for determining a fault location in an electrical power network comprising multi-conductor lines, comprises measuring at an observation point located anywhere along one of the multi-conductor lines, for each of the conductors of the multi-conductor line, respectively a fault-originated electromagnetic transient signal; defining a set of guessed fault locations each having a different determined location in the electrical power network, and each of the guessed fault locations is attributed a same arbitrary fault impedance; defining a network model for the electrical power network, based on its topology and multi-conductor lines electrical parameters capable of reproducing in the network model the electromagnetic traveling waves; and computing for each conductor a time inversion of the measured fault-originated electromagnetic transients signal.

Abstract: The device comprises at least an inlet tube for the passage of fluid to be drained, said tube being connected to a chamber wherein said chamber comprises rotating means for adjusting the flow rate in said tube.

Abstract: The present invention relates to modified surfaces. The surfaces comprise an inorganic material on which a phosphinic acid derivative is adsorbed. The phosphinic acid thus turns out to be a new anchoring group useful for surface derivatization. The invention has many applications for photoelectric conversion devices, batteries, capacitors, electrochromic displays, chemical sensors, biological sensors, light emitting diodes, electrodes, semiconductors, separation membranes, selective adsorbents, adsorbents for HPLC, catalysts, implants, nanoparticles, antiadhesives, and anticorrosion coatings, for example.

Abstract: The present invention provides a closed-loop system for real-time control of epidural and/or subdural electrical stimulation comprising: means for applying to a subject neuromodulation with adjustable stimulation parameters, said means being operatively connected with a real-time monitoring component comprising sensors continuously acquiring feedback signals from said subject, said signals being neural signals and/or signals providing features of motion of said subject, said system being operatively connected with a signal processing device receiving said feedback signals and operating real-time automatic control algorithms, said signal processing device being operatively connected with said means and providing said means with new stimulation parameters, with minimum delay. The system of the invention improves consistency of walking in a subject with a neuromotor impairment.

Abstract: The invention relates to a microfluidic circuit including at least one microchannel for the flow of a first fluid conveying drops or bubbles of at least one second fluid, characterized in that the height of the microchannel is sized so as to crush the drops or bubbles during the movement thereof, and in that the microchannel comprises at least one trough, extending at least partially in the direction of flow of the first fluid or an area for trapping drops or bubbles, said area or the trough having a height that is greater than the height of the microchannel, such that at least some of the drops or bubbles of the second fluid in the microchannel are drawn and guided into the trough or into the trapping area.

Abstract: A method and device for the rapid detection of biomolecules (320) diffusing in a nanometer-confined slit (204) is claimed. In particular, the present invention relates to a novel concept of fluidic side apertures (205) that facilitates the filling of the device, the surface coating with biomolecules and that measures the affinity between fluorescently labeled biomolecules in aqueous solution with other biomolecules immobilized on surfaces.

Abstract: An aerial vehicle including self-autonomous deployable arms and methods of deploying the vehicle are disclosed. The arms may include patterns located thereon that allow the arms to transition between wrapped, flat, and deployed configurations autonomously without the need for direct intervention by a user.

Abstract: A system and method for local multiplayer gaming are disclosed. According to one embodiment, a system comprises a plurality of mobile client devices including a mobile client device designated as a server device. Each mobile client device comprises a display, at least one local network interface for communication with said server device and a processor. The processor is programmed for playing a multiplayer game with other mobile client devices and rendering on said display a game situation depending on commands sent by a plurality of mobile client devices to said server device over said at least local network interface. At least one of said mobile client devices is configured for overhearing commands sent by at least one other mobile client device to said server device or another mobile client device and for rendering on its display a game situation depending on said overheard command.

Abstract: Described herein are microelectrode array devices, and methods of fabrication and use of the same, to provide highly localized and efficient electrical stimulation of a neurological target. The device includes multiple microelectrode elements arranged along an elongated probe shaft. The microelectrode elements are dimensioned and shaped so as to target individual neurons, groups of neurons, and neural tissue as may be located in an animal nervous system, such as deep within a human brain. Beneficially, the neurological probe can be used to facilitate location of the neurological target and remain implanted for long-term monitoring and/or stimulation.