Abstract: A collagen matrix material is charged with a cell growth-promoting derived nucleic acid sequence. The nucleic acid sequence-charged collagen matrix material may be utilized in a method of promoting regeneration of surface cartilage of a joint. In the method, an area of injury is covered with the nucleic acid sequence-charged collagen matrix material, the collagen matrix material is fixed over the area to be treated, and the area is allowed to heal.
Type:
Application
Filed:
August 7, 2002
Publication date:
February 27, 2003
Applicant:
ED. GEISTLICH SOEHNE AG FUER CHEMISCHE INDUSTRIE
Abstract: A method of therapeutic treatment of an area of severe infection of soft tissue within or surrounding a tooth of a patient involves administering Taurolidine, Taurultam or mixtures thereof to the area of severe infection.
Type:
Grant
Filed:
July 1, 1999
Date of Patent:
December 3, 2002
Assignee:
Ed. Geistlich Soehne AG fuer Chemische Industrie
Inventors:
Rolf Wilhelm Pfirrmann, Peter Geistlich
Abstract: A method of promoting regeneration of surface cartilage of a joint includes the steps of forming punctures in a subchondral plate of an area of the joint to be treated, covering the puncture and the area to be treated with a chondrocyte-free patch made of a sheet of collagen membrane material without adding chondrocytes to the area to be treated, fixing the patch over the area to be treated, and allowing the area to be treated to regenerate cartilage without adding chondrocytes to the area to be treated.
Type:
Grant
Filed:
December 29, 1999
Date of Patent:
March 5, 2002
Assignee:
Ed. Geistlich Soehne AG fuer Chemische Industrie
Abstract: A resorbable extracellular matrix for reconstruction of cartilage tissue, the matrix being substantially free from non-native collagen, and including a purified collagen II material formed form natural cartilage and having fibers of native collagen II which are physiologically acceptable for implant into a mammalian body.
Type:
Grant
Filed:
November 10, 1997
Date of Patent:
December 4, 2001
Assignee:
Ed Geistlich Soehne AG fuer Chemische Industrie
Inventors:
Peter Geistlich, Myron Spector, Zdenek Eckmayer
Abstract: The use of taurolidine or taurultam in a method of combatting infection or sepsis in delivery systems is disclosed. In the method, taurolidine or taurultam solutions are used as a temporary seal or flush to prevent or reduce sepsis in delivery systems, such as port systems and/or catheters by which liquids are delivered into a patient.
Type:
Grant
Filed:
June 21, 1999
Date of Patent:
July 10, 2001
Assignee:
Ed. Geistlich Soehne AG fuer Chemische Industrie