Patents Assigned to ElectroCore, Inc.
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Publication number: 20240108880Abstract: Devices, systems and methods are disclosed for treating one or more symptoms of a central nervous system disorder in a patient, such as fibromyalgia, anxiety, traumatic brain injury or post-traumatic stress disorder (PTSD). A device comprises one or more electrodes configured for contacting an outer skin surface of the patient and an energy source coupled to the electrodes. The energy source generates at least one electrical impulse and transmits the at least one electrical impulse transcutaneously from the electrodes through the outer skin surface of the patient to a vagus nerve in the patient for about ninety seconds to about 3 minutes. The electrical impulse is sufficient to modify the vagus nerve such that the symptoms of the disorder are reduced.Type: ApplicationFiled: December 1, 2023Publication date: April 4, 2024Applicant: ElectroCore, Inc.Inventors: Bruce J. Simon, Joseph P. Errico
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Patent number: 11944807Abstract: Devices, systems and methods are disclosed for treating one or more symptoms of central nervous system disorders in a patient, such as anxiety disorders, fibromyalgia, traumatic brain injury, PTSD, and others. A method includes positioning a contact surface of a device in contact with an outer skin surface of patient and applying an electrical impulse transcutaneously from the device through the outer skin surface of the patient to a vagus nerve in the patient for about 90 seconds to about 3 minutes. The electrical impulse is sufficient to modify the vagus nerve such that the symptoms of the central nervous system disorder are reduced. For chronic treatment of such disorders, a stimulation protocol is provided that includes two or more doses administered per day for a period of time sufficient to relieve the symptoms.Type: GrantFiled: September 22, 2021Date of Patent: April 2, 2024Assignee: Electrocore, Inc.Inventors: Bruce J. Simon, Joseph P. Errico
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Patent number: 11944815Abstract: Devices, systems and methods are disclosed that allow a patient to self-treat a medical condition, such as headache, by noninvasive stimulation of a nerve. A system comprises a stimulator having an interface configured to contact an outer skin surface of a patient and an energy source coupled to the interface. The energy source transmits an electrical impulse through the interface transcutaneously through the outer skin surface of the patient to a nerve of the patient such that the nerve is modulated. The system further comprises a mobile device coupled to the stimulator to transmit data to the stimulator. The data includes a therapy regimen to reduce one or more symptoms of a headache in the patient.Type: GrantFiled: November 9, 2021Date of Patent: April 2, 2024Assignee: ELECTROCORE, INC.Inventors: Bruce J. Simon, Joseph P. Errico, John T. Raffle
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Publication number: 20240090821Abstract: Systems and methods for remote therapy and patient monitoring are provided. A method comprises contacting an outer skin surface of a patient with a contact surface of a stimulator and transmitting an electrical impulse from the stimulator transcutaneously through the outer skin surface to a nerve within the patient. Data related to parameters of the electrical impulse applied to the nerve is stored and transmitted to a remote source. The data may include duration of treatment, amplitude of the electrical impulse, compliance with a prescribed therapy regimen or other relevant data related to the therapy. The method may further include collecting patient status data, such as symptoms of a medical condition (e.g., severity of a headache) before, during and/or after stimulation. The patient status data is correlated with the treatment data to monitor compliance and/or the effectiveness of the therapy.Type: ApplicationFiled: November 13, 2023Publication date: March 21, 2024Applicant: ElectroCore, Inc.Inventors: Bruce J. Simon, Joseph P. Errico
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Publication number: 20240087736Abstract: A medical device, such as a neurostimulator, is provided that includes a housing, a power supply, a signal generator and one or more electrodes coupled to the housing. The signal generator is configured to apply one or more electrical impulses to the one or more electrodes for a period of time, the period of time being defined as a single dose. The device is configured to switch from an activated mode and a deactivated mode after specific number of single doses have been emitted by the signal generator.Type: ApplicationFiled: November 15, 2023Publication date: March 14, 2024Applicant: ElectroCore, Inc.Inventors: Joseph P. Errico, Francis R. Amato, Steven M. Mendez, Hecheng Hu
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Publication number: 20240058605Abstract: Systems and methods are disclosed that allow a patient to self-treat a medical condition, such as migraine headache and trigeminal neuralgia and the like. The system comprises a stimulator configured for wireless coupling to a mobile device and comprising a signal generator that generates an electrical impulse and an energy source. The stimulator includes a contact surface configured to contact an outer skin surface of a head of a patient and a user interface for selecting a therapy regimen. The stimulator transmits the electrical impulse transcutaneously through the outer skin surface to a nerve at a target region of the head, wherein the electrical impulse is sufficient to modulate the nerve and modify the medical condition. The system further comprises a software program downloadable onto the mobile device and configured to communicate with the stimulator.Type: ApplicationFiled: November 1, 2023Publication date: February 22, 2024Applicant: ElectroCore, Inc.Inventors: Joseph P. Errico, Steven Mendez, Bruce J. Simon
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Publication number: 20240050733Abstract: Systems and methods are provided for delivering energy impulses (and/or fields) to bodily tissues. In certain aspects, the systems and methods are particularly useful for temporarily or permanently improving intelligence, learning capacity, memory retention, recall, mood, alertness and/or sleep efficiency in human beings. In certain embodiments, the methods and devices enhance neurostructural development over a period of time by increasing neurogenesis, neuronal plasticity and/or neural connectivity efficiency, and/or by improving the chemical microenvironment of the evolving neural network. In some embodiments, these enhancements may provide temporary improvement to enable an individual to, for example, accomplish a particular task while under duress, sleep deprivation, stress, anxiety or the like. In other embodiments, these changes permanently enhance the intelligence, emotional stability, and overall brain health of the treated individual.Type: ApplicationFiled: October 23, 2023Publication date: February 15, 2024Applicant: ElectroCore, Inc.Inventors: Bruce J. Simon, Joseph P. Errico
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Patent number: 11865329Abstract: Devices, systems and methods are disclosed for treating one or more symptoms of post-traumatic stress disorder (PTSD) in a patient. A method includes positioning a contact surface of a device in contact with an outer skin surface of patient and applying an electrical impulse transcutaneously from the device through the outer skin surface of the patient to a vagus nerve in the patient for about 90 seconds to about 3 minutes. The electrical impulse is sufficient to modify the vagus nerve such that the symptoms of PTSD are reduced. For chronic treatment of PTSD, a stimulation protocol is provided that includes two or more doses administered per day for a period of time sufficient to relieve the symptoms.Type: GrantFiled: August 30, 2021Date of Patent: January 9, 2024Assignee: ElectroCore, Inc.Inventors: Bruce J. Simon, Joseph P. Errico
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Patent number: 11854695Abstract: A medical device, such as a neurostimulator, is provided that includes a housing, a power supply, a signal generator and one or more electrodes coupled to the housing. The signal generator is configured to apply one or more electrical impulses to the one or more electrodes for a period of time, the period of time being defined as a single dose. A memory is coupled to the housing and stores a first content corresponding to a time period that has elapsed and a second content corresponding to a number of single doses that have been emitted by the signal generator. The device is configured to switch from an activated mode and a deactivated mode upon a first occurrence of either a specific number of single doses have been emitted by the signal generator or a specific time period has elapsed.Type: GrantFiled: January 19, 2023Date of Patent: December 26, 2023Assignee: ELECTROCORE, INCInventors: Joseph P. Errico, Francis R. Amato, Steven M. Mendez, Hecheng Hu
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Patent number: 11850056Abstract: Systems and methods for remote therapy and patient monitoring are provided. A method comprises contacting an outer skin surface of a patient with a contact surface of a stimulator and transmitting an electrical impulse from the stimulator transcutaneously through the outer skin surface to a nerve within the patient. Data related to parameters of the electrical impulse applied to the nerve is stored and transmitted to a remote source. The data may include duration of treatment, amplitude of the electrical impulse, compliance with a prescribed therapy regimen or other relevant data related to the therapy. The method may further include collecting patient status data, such as symptoms of a medical condition (e.g., severity of a headache) before, during and/or after stimulation. The patient status data is correlated with the treatment data to monitor compliance and/or the effectiveness of the therapy.Type: GrantFiled: July 27, 2022Date of Patent: December 26, 2023Assignee: ElectroCore, Inc.Inventors: Bruce J. Simon, Joseph P. Errico
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Publication number: 20230405319Abstract: Devices, systems and methods are provided for treating various symptoms, disorders and medical conditions through noninvasive stimulation of a nerve. A system comprises a stimulator including an electrode configured to contact an outer skin surface of a patient and a user interface for turning the stimulator ON to enable the stimulator to operate. An energy source is coupled to the stimulator to generate an electrical impulse, wherein the stimulator transmits the electrical impulse from the electrode transcutaneously through an outer skin surface of an individual to a selected nerve within the individual. The system further comprises a software application coupled to the stimulator and configured to transmit data to the stimulator. The data may include authorization for the stimulator to transmit the electrical impulse.Type: ApplicationFiled: June 6, 2023Publication date: December 21, 2023Applicant: ElectroCore, Inc.Inventors: Bruce J. Simon, Joseph P. Errico, John T. Raffle
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Publication number: 20230405306Abstract: Systems and methods are provided for delivering energy impulses (and/or fields) to bodily tissues. In certain aspects, the systems and methods are particularly useful for temporarily or permanently improving intelligence, learning capacity, memory retention, recall, mood, alertness and/or sleep efficiency in human beings. In certain embodiments, the methods and devices enhance neurostructural development over a period of time by increasing neurogenesis, neuronal plasticity and/or neural connectivity efficiency, and/or by improving the chemical microenvironment of the evolving neural network. In some embodiments, these enhancements may provide temporary improvement to enable an individual to, for example, accomplish a particular task while under duress, sleep deprivation, stress, anxiety or the like. In other embodiments, these changes permanently enhance the intelligence, emotional stability, and overall brain health of the treated individual.Type: ApplicationFiled: June 20, 2022Publication date: December 21, 2023Applicant: ElectroCore, Inc.Inventors: Bruce J. Simon, Joseph P. Errico
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Publication number: 20230398352Abstract: Devices, systems and methods are disclosed for treating symptoms of a user, such as anxiety, depression and/or epileptic seizures, by electrical non-invasive stimulation of a nerve, such as the vagus nerve. A stimulator has a contact surface for contacting an outer skin surface of a patient. The stimulator is configured to wirelessly receive a signal from the software application that includes an electrical stimulation signal comprising at least one electrical impulse sufficient to modulate a nerve within a patient and to ameliorate one or more symptoms in the patient. The stimulator is configured to transmit the electrical impulse through the contact surface and the outer skin surface of the user.Type: ApplicationFiled: August 15, 2023Publication date: December 14, 2023Applicant: ElectroCore, Inc.Inventors: Joseph P. Errico, Steven Mendez, Bruce J. Simon
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Patent number: 11839764Abstract: Systems and methods are disclosed that allow a patient to self-treat a medical condition, such as migraine headache and trigeminal neuralgia and the like, by noninvasive electrical stimulation of nerves of the head, particularly supraorbital, supratrochlear, infraorbital, and mental nerves in the vicinity of their foramen or notch. The system comprises a stimulator having one or more electrodes that apply electrical impulses transcutaneously through the patient's skin to the targeted nerve. The stimulator may be coupled to a handheld mobile device, such as a smartphone, for receiving a treatment regimen to treat the medical condition. The system is designed to address problems that arise particularly during self-treatment, when a medical professional is not present.Type: GrantFiled: June 13, 2021Date of Patent: December 12, 2023Assignee: ElectroCore, Inc.Inventors: Joseph P. Errico, Steven Mendez, Bruce J. Simon
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Publication number: 20230381499Abstract: Devices, systems and methods are disclosed for electrical stimulation of nerves to treat one or more symptoms in a user. The methods comprise transcutaneously transmitting electrical impulses to the nerve according to a treatment paradigm. The treatment paradigm may include generating and transmitting the electrical impulse as a single dose from about 30 seconds to about 5 minutes. The treatment paradigm may comprise a treatment session of 2 to 4 times within an hour time period and/or as a single dose from 2 to 5 times during a day.Type: ApplicationFiled: August 1, 2023Publication date: November 30, 2023Applicant: ElectroCore, Inc.Inventors: Bruce J. Simon, Joseph P. Errico
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Publication number: 20230381507Abstract: Devices, systems and methods are disclosed that allow a patient to self-treat a medical condition, such as migraine headache, by electrical non-invasive stimulation of a nerve, such as the trigeminal nerve. A system comprises one or more electrodes configured for contacting an outer skin surface of a patient and a stimulator coupled to the one or more electrodes. The stimulator is configured to transmit an electrical impulse from the electrodes through the outer skin surface to a target site within a patient. A software application coupled to the stimulator. The software application may, for example, be downloadable onto a mobile device and may allow the user to transmit data to and from the stimulator and/or control operation of the stimulator.Type: ApplicationFiled: May 25, 2023Publication date: November 30, 2023Applicant: ElectroCore, Inc.Inventors: Joseph P. Errico, Steven Mendez, Bruce J. Simon
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Patent number: 11779756Abstract: Devices, systems and methods are disclosed for electrical stimulation of the vagus nerve to treat or prevent disorders in a patient. The methods comprise transmitting impulses of energy to the vagus nerve according to a treatment paradigm. The treatment paradigm may include generating and transmitting the electrical impulse as a single dose from about 30 seconds to about 5 minutes. The treatment paradigm may comprise a treatment session of 2 to 4 times within an hour time period and/or as a single dose from 2 to 5 times during a day.Type: GrantFiled: June 17, 2022Date of Patent: October 10, 2023Assignee: ElectroCore, Inc.Inventors: Bruce J. Simon, Joseph P. Errico
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Patent number: 11766562Abstract: Devices, systems and methods are disclosed for treating seizures, such as epileptic seizures, by electrical non-invasive stimulation of a nerve, such as the vagus nerve. A stimulator comprises a contact surface, such as an electrode, for contacting an outer skin surface of a patient. The stimulator is configured for coupling to a mobile device configured to receive a wireless signal. The stimulator is configured to transmit the electrical impulse through the contact surface and the outer skin surface sufficient to modulate a nerve within a patient and to ameliorate one or more symptoms of a seizure in the patient.Type: GrantFiled: December 4, 2021Date of Patent: September 26, 2023Assignee: ElectroCore, Inc.Inventors: Joseph P. Errico, Steven Mendez, Bruce J. Simon
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Publication number: 20230277844Abstract: A system is provided that includes a medical device comprising a power supply, a signal generator and an electrode. The signal generator is configured to apply one or more electrical impulses to the electrode for a period of time defined as a single dose. The system further comprises a processor coupled to the medical device. The processor is configured to switch the medical device from an activated mode to a deactivated mode after a specific number of single doses have been applied by the signal generator.Type: ApplicationFiled: May 12, 2023Publication date: September 7, 2023Applicant: ElectroCore, Inc.Inventors: Joseph P. Errico, Arthur F. Ross, Muhammad Basit Qari
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Publication number: 20230277838Abstract: Devices, systems and methods are provided for symptoms in patients, such as postoperative symptoms following major surgery and/or for treating patients in critical or intensive care. A device includes a patch having an adhesive surface for adhering to an outer skin surface of the patient and comprising one or more electrodes. An energy source is wirelessly coupled to the electrodes and configured to generate at least one electrical impulse and to wirelessly transmit the at least one electrical impulse transcutaneously from the electrodes through the outer skin surface of the patient to a selected nerve in the patient according to a stimulation protocol. The stimulation protocol includes administering at least one dose of about sixty seconds to about 5 minutes each day for a plurality of days. The doses may be administered before and after the patient’s surgery, or while the patient is being treating in intensive care.Type: ApplicationFiled: January 2, 2023Publication date: September 7, 2023Applicant: ELECTROCORE, INCInventors: J. P. Errico, Bruce J. Simon, Peter Staats