Patents Assigned to ElectroCore, Inc.
  • Publication number: 20250134444
    Abstract: Systems and methods for non-invasive nerve stimulation are provided. A method for treating a patient with a medical condition comprises contacting an outer skin surface of a patient with a contact surface of a stimulator, generating an electrical impulse, and transmitting the electrical impulse from the stimulator transcutaneously through the outer skin surface to a nerve within the patient. The method further includes detecting a physiological parameter of the patient during the transmitting and modifying one or more parameters of the electrical impulse applied to the nerve based on the physiological parameter.
    Type: Application
    Filed: January 2, 2025
    Publication date: May 1, 2025
    Applicant: ElectroCore, Inc.
    Inventors: Bruce J. Simon, Joseph P. Errico
  • Publication number: 20250117545
    Abstract: Devices and methods are described to produce therapeutic effects in a patient by utilizing an energy source that transmits energy non-invasively to nervous tissue. A device for modulating a nerve within a body of a patient comprises a housing comprising a power supply and a signal generator for generating an electrical impulse. The electrical impulse comprises bursts of 2 to 20 pulses, wherein each of the bursts has a frequency of 15 to 50 Hz. The device further comprises first and second electrodes coupled to the housing and having a contact surface configured for contacting an outer skin surface of a neck of a user. The energy source is configured to transmit the electrical impulse from the first and second electrodes through the outer skin surface of the user to a vagus nerve.
    Type: Application
    Filed: December 17, 2024
    Publication date: April 10, 2025
    Applicant: ElectroCore, Inc.
    Inventors: Bruce J. Simon, Joseph P. Errico, John T. Raffle
  • Publication number: 20250099753
    Abstract: Systems, devices and methods are provided for delivering electrical impulses to bodily tissues for therapeutic purposes. A system for stimulating a nerve within a patient comprises a stimulator having an electrode configured for contacting the outer skin surface at, or near the target location and an energy source coupled to the stimulator, The energy source is configured to generate at least one electrical impulse and to transmit the electrical impulse transcutaneously from the electrode through the outer skin surface of the patient to a selected nerve in the patient adjacent to, or near, the target location. The system may include a wearable treatment device designed to optimize placement of the electrode at the target site.
    Type: Application
    Filed: September 20, 2024
    Publication date: March 27, 2025
    Applicant: ElectroCore, Inc.
    Inventors: Jeckin Shah, Jonathan Gardiner, Dan Goldberger, Manuel A. Marques
  • Publication number: 20250082924
    Abstract: Devices and methods for the non-invasive stimulation of nerves, such as the vagus nerve, include a housing and an electrode coupled to the housing. The electrode is configured to be positioned adjacent to, or in contact with, an outer skin surface of a patient. A source of energy is coupled to the housing and operably coupled to the electrode. The source of energy emits an electrical impulse to the electrode such that the electrical impulse passes through the outer skin surface of the patient to a nerve at a target region in the patient sufficient to modulate the nerve.
    Type: Application
    Filed: November 26, 2024
    Publication date: March 13, 2025
    Applicant: ElectroCore, Inc.
    Inventors: Bruce J. Simon, Joseph P. Errico, John T. Raffle
  • Publication number: 20250065120
    Abstract: A system is provided that includes a medical device comprising a power supply, a signal generator and an electrode. The signal generator is configured to apply one or more electrical impulses to the electrode for a period of time defined as a single dose. The system further comprises a downloadable software application coupled to the medical device. The software application is configured to switch the medical device from an activated mode to a deactivated mode after a specific number of single doses have been applied by the signal generator.
    Type: Application
    Filed: November 12, 2024
    Publication date: February 27, 2025
    Applicant: ElectroCore, Inc.
    Inventors: Joseph P. Errico, Arthur F. Ross, Muhammad Basit Qari
  • Publication number: 20250058106
    Abstract: Methods and devices are provided for the non-invasive treatment of diseases or disorders, such as Alzheimer's disease, Parkinson's disease, rheumatoid arthritis (RA), multiple sclerosis, postoperative cognitive dysfunction, or postoperative delirium. A device comprises a stimulator having an electrode configured for contacting an outer skin surface of a neck of the patient and an energy source configured to transmit, via the electrode, an electric current transcutaneously and non-invasively through the outer skin surface of the neck of the patient to generate an electrical impulse at or near a vagus nerve within the patient. The electrical impulse comprises bursts of 2 to 20 pulses with each of the bursts comprising a frequency from about 15 Hz to about 50 Hz and with each of the pulses comprising a duration from about 20 microseconds to about 1000 microseconds.
    Type: Application
    Filed: November 7, 2024
    Publication date: February 20, 2025
    Applicant: ElectroCore, Inc.
    Inventors: Bruce J. Simon, Joseph P. Errico, John T. Raffle
  • Patent number: 12208263
    Abstract: Devices and methods are described to produce therapeutic effects in a patient by utilizing an energy source that transmits energy non-invasively to nervous tissue. A device for modulating a nerve within a body of a patient comprises a housing comprising a power supply and a signal generator for generating an electrical impulse. The electrical impulse comprises bursts of 2 to 20 pulses, wherein each of the bursts has a frequency of 15 to 50 Hz. The device further comprises first and second electrodes coupled to the housing and having a contact surface configured for contacting an outer skin surface of a neck of a user. The energy source is configured to transmit the electrical impulse from the first and second electrodes through the outer skin surface of the user to a vagus nerve.
    Type: Grant
    Filed: May 2, 2024
    Date of Patent: January 28, 2025
    Assignee: ELECTROCORE, INC.
    Inventors: Bruce J. Simon, Joseph P. Errico, John T. Raffle
  • Patent number: 12179012
    Abstract: Devices and methods for the non-invasive stimulation of nerves, such as the vagus nerve, include a housing and an electrode coupled to the housing. The electrode is configured to be positioned adjacent to, or in contact with, an outer skin surface of a patient. A source of energy is coupled to the housing and operably coupled to the electrode. The source of energy emits an electrical impulse to the electrode such that the electrical impulse passes through the outer skin surface of the patient to a nerve at a target region in the patient sufficient to modulate the nerve. The electrical impulse comprises burst periods and constant periods, wherein each burst period includes 2 to 20 pulses and has a duration of less than 20,000 microseconds.
    Type: Grant
    Filed: April 5, 2022
    Date of Patent: December 31, 2024
    Assignee: ElectroCore, Inc.
    Inventors: Bruce J. Simon, Joseph P. Errico, John T. Raffle
  • Patent number: 12172016
    Abstract: A system is provided that includes a medical device comprising a power supply, a signal generator and an electrode. The signal generator is configured to apply one or more electrical impulses to the electrode for a period of time defined as a single dose. The system further comprises a processor coupled to the medical device. The processor is configured to switch the medical device from an activated mode to a deactivated mode after a specific number of single doses have been applied by the signal generator.
    Type: Grant
    Filed: May 12, 2023
    Date of Patent: December 24, 2024
    Assignee: ElectroCore, Inc.
    Inventors: Joseph P. Errico, Arthur F. Ross, Muhammad Basit Qari
  • Patent number: 12172015
    Abstract: Methods and devices are provided for the non-invasive treatment of diseases or disorders, such as Alzheimer's disease, Parkinson's disease, rheumatoid arthritis (RA), multiple sclerosis, postoperative cognitive dysfunction, or postoperative delirium. A method for comprises positioning an electrode in contact with an outer skin surface of a neck of the patient and transmitting, via the electrode, an electric current transcutaneously and non-invasively through the outer skin surface of the neck of the patient to generate an electrical impulse at or near a vagus nerve within the patient. The electrical impulse comprises bursts of 2 to 20 pulses with each of the bursts comprising a frequency from about 15 Hz to about 50 Hz and with each of the pulses comprising a duration from about 20 microseconds to about 1000 microseconds.
    Type: Grant
    Filed: January 5, 2024
    Date of Patent: December 24, 2024
    Assignee: ElectroCore, Inc.
    Inventors: Bruce J. Simon, Joseph P. Errico, John T. Raffle
  • Patent number: 12168121
    Abstract: Devices, systems and methods are disclosed for treating or preventing a developmental disorder, such as attention-deficit hyperactivity disorder (ADHD), an autism spectrum disorder, Asperger syndrome, childhood disintegrative disorder, overactive disorder, pervasive developmental disorder. A device comprises an electrode having a contact surface for contacting an outer skin surface of a patient and a power source coupled the electrode. The power source generates and transmits an electrical impulse having a frequency of about 1 kHz to about 20 kHz through the contact surface and the outer skin surface to a nerve within the patient. The electrical impulse is sufficient to modify the behavioral disorder in the patient.
    Type: Grant
    Filed: December 19, 2022
    Date of Patent: December 17, 2024
    Assignee: ELECTROCORE, INC.
    Inventors: Bruce J. Simon, Joseph P. Errico, John T. Raffle
  • Patent number: 12168128
    Abstract: Systems and methods are disclosed that allow a patient to self-treat a medical condition, such as migraine headache and trigeminal neuralgia and the like. The system comprises a stimulator configured for wireless coupling to a mobile device and comprising a signal generator that generates an electrical impulse and an energy source. The stimulator includes a contact surface configured to contact an outer skin surface of a head of a patient and a user interface for selecting a therapy regimen. The stimulator transmits the electrical impulse transcutaneously through the outer skin surface to a nerve at a target region of the head, wherein the electrical impulse is sufficient to modulate the nerve and modify the medical condition. The system further comprises a software program downloadable onto the mobile device and configured to communicate with the stimulator.
    Type: Grant
    Filed: November 1, 2023
    Date of Patent: December 17, 2024
    Assignee: ELECTROCORE, INC.
    Inventors: Joseph P. Errico, Steven Mendez, Bruce J. Simon
  • Publication number: 20240374889
    Abstract: Vagal nerve stimulation devices and methods are provided herein. A device comprises one or more electrodes having a contact surface for contacting an outer skin surface of a patient and an energy source coupled to the electrodes. The energy source generates one or more electrical impulses and transmits the electrical impulses to the electrodes and transcutaneously through the outer skin surface of the patient at or near a vagus nerve. The one or more electrical pulses comprise bursts of 2 to 20 pulses within each burst with each burst having a frequency of about 5 Hz to about 100 Hz.
    Type: Application
    Filed: July 22, 2024
    Publication date: November 14, 2024
    Applicant: ElectroCore, Inc.
    Inventors: Bruce J. Simon, Joseph P. Errico, John T. Raffle
  • Publication number: 20240350802
    Abstract: Methods for treating medical disorders, such as migraine or other primary headaches, or fibromyalgia, by electrical stimulation of a nerve. The method comprises applying a stimulus to a patient having a medical condition and measuring a baseline physiological response from the patient. An electrical impulse is applied to a nerve within the patient and the response evoked by the electrical impulse is measured and compared to the first baseline physiological response. The methods may be used to optimize the placement of a stimulator, to test whether a patient is a suitable candidate for treatment using nerve stimulation, and/or to select the stimulation parameters that optimize acute or chronic treatment.
    Type: Application
    Filed: June 26, 2024
    Publication date: October 24, 2024
    Applicant: Electrocore, Inc.
    Inventors: Bruce J. Simon, Joseph P. Errico
  • Publication number: 20240316342
    Abstract: Devices, systems, and methods are provided for treating various symptoms, disorders and medical conditions through noninvasive stimulation of a nerve. A system comprises a stimulator having an interface configured to contact an outer skin surface of a user and an energy source coupled to the interface. The energy source transmits an electrical signal comprising a plurality of electrical impulses through the interface transcutaneously through the outer skin surface of the user to a nerve of the user such that the nerve is modulated. The system further comprises a downloadable software application downloadable onto a mobile device configured for wireless coupling to the stimulator to transmit data from the software application to the stimulator. The downloadable software application controls a duration of time in which the stimulator generates the electrical signal.
    Type: Application
    Filed: March 4, 2024
    Publication date: September 26, 2024
    Applicant: ElectroCore, Inc.
    Inventors: Bruce J. Simon, Joseph P. Errico, John T. Raffle
  • Patent number: 12070593
    Abstract: Vagal nerve stimulation devices and methods are provided for treating medical conditions, such as conditions associated with insufficient dopamine and/or endogenous opioids in the brain. A device includes one or more electrodes having a contact surface for contacting an outer skin surface of a patient and an energy source coupled to the electrodes. The energy source generates one or more electrical impulses and transmits the electrical impulses to the electrodes and transcutaneously through the outer skin surface of the patient at or near a vagus nerve. The one or more electrical impulses is sufficient to modulate the vagus nerve and release dopamine and/or endogenous opioids in a brain of the patient.
    Type: Grant
    Filed: March 6, 2023
    Date of Patent: August 27, 2024
    Assignee: ELECTROCORE, INC
    Inventors: Bruce J. Simon, Joseph P. Errico, John T. Raffle
  • Publication number: 20240278012
    Abstract: Devices and methods are described to produce therapeutic effects in a patient by utilizing an energy source that transmits energy non-invasively to nervous tissue. A device for modulating a nerve within a body of a patient comprises a housing comprising a power supply and a signal generator for generating an electrical impulse. The electrical impulse comprises bursts of 2 to 20 pulses, wherein each of the bursts has a frequency of 15 to 50 Hz. The device further comprises first and second electrodes coupled to the housing and having a contact surface configured for contacting an outer skin surface of a neck of a user. The energy source is configured to transmit the electrical impulse from the first and second electrodes through the outer skin surface of the user to a vagus nerve.
    Type: Application
    Filed: May 2, 2024
    Publication date: August 22, 2024
    Applicant: ElectroCore, Inc.
    Inventors: Bruce J. Simon, Joseph P. Errico, John T. Raffle
  • Patent number: 12053631
    Abstract: Methods for treating medical disorders, such as migraine or other primary headaches, or fibromyalgia, by electrical stimulation of a nerve. The method comprises applying a first stimulus to a patient having a medical condition and measuring a first baseline physiological response from the patient. An electrical impulse is applied to a nerve within the patient and second stimulus is applied to the patient. A second physiological response evoked by the second stimulus is measured and compared to the first baseline physiological response. The methods may be used to optimize the placement of a stimulator, to test whether a patient is a suitable candidate for treatment using nerve stimulation, and/or to select the stimulation parameters that optimize acute or chronic treatment.
    Type: Grant
    Filed: May 12, 2021
    Date of Patent: August 6, 2024
    Assignee: ELECTROCORE, INC
    Inventors: Bruce J. Simon, Joseph P. Errico
  • Publication number: 20240216682
    Abstract: Systems, devices and methods are provided for delivering energy impulses (and/or fields) to bodily tissues for therapeutic purposes. A system for stimulating a nerve within a patient comprises a stimulator having an electrode configured for contacting the outer skin surface at, or near the target location and an energy source coupled to the stimulator, The energy source is configured to generate at least one electrical impulse and to transmit the electrical impulse transcutaneously from the electrode through the outer skin surface of the patient to a selected nerve in the patient adjacent to, or near, the target location. The system further comprises a software application configured for downloading onto a user interface. The software application controls parameters of the stimulator, which may be based on a physiological parameter of the patient and/or user status information related to the effectiveness of the therapy.
    Type: Application
    Filed: December 27, 2023
    Publication date: July 4, 2024
    Applicant: ElectroCore, Inc.
    Inventors: Jeckin Shah, Tanja Martin, Mike Romaniw, Muhammad Basit Qari
  • Publication number: 20240198086
    Abstract: Devices and methods are disclosed for treating one or more symptoms of a central nervous system disorder in a patient, such as fibromyalgia, anxiety, traumatic brain injury or post-traumatic stress disorder (PTSD). A device comprises one or more electrodes configured for contacting an outer skin surface of the patient and an energy source coupled to the electrodes. The energy source generates at least one electrical impulse and transmits the electrical impulse transcutaneously from the electrodes through the outer skin surface of the patient to a vagus nerve in the patient. The electrical impulse comprises a burst period and a constant period. Each burst period comprises 2 to 20 pulses that alternate between a positive and negative electric field charge and at least a portion of each constant period comprises zero pulses. The electrical impulse is sufficient to modify the vagus nerve such that the symptoms of the disorder are reduced.
    Type: Application
    Filed: March 1, 2024
    Publication date: June 20, 2024
    Applicant: ElectroCore, Inc.
    Inventors: Bruce J. Simon, Joseph P. Errico