Abstract: Systems and methods are disclosed for treatment of metabolic disorders such as type 2 diabetes and obesity by stimulation of the small intestine to modulate hormone production. Methods include applying an appropriate signal to a region of the small intestine to modulate hormone production. The method may involve applying a signal to the nerves that innervate the small intestine. Devices for delivering the signal are disclosed.

Abstract: Devices, systems and methods for treating bronchial constriction related to asthma, anaphylaxis or chronic obstructive pulmonary disease wherein the treatment includes stimulating selected nerve fibers responsible for smooth muscle dilation at a selected region within a patient's neck, thereby reducing the magnitude of constriction of bronchial smooth muscle.

Abstract: A method of treating a temporary arrest of intestinal peristalsis includes inducing at least one of an electric current, an electric field and an electromagnetic field in a sympathetic nerve chain of a mammal to block and/or modulate inhibitory nerve signals thereof such that intestinal peristalsis function is at least partially improved.

Abstract: A method of treating a temporary arrest of intestinal peristalsis includes inducing at least one of an electric current, an electric field and an electromagnetic field in a sympathetic nerve chain of a mammal to block and/or modulate inhibitory nerve signals thereof such that intestinal peristalsis function is at least partially improved.

Abstract: Devices and methods for treating patients suffering from an eating disorder, such as obesity and/or pathologies resulting in obesity, by regulating sensations affecting food consumption. The devices and methods may facilitate appropriate caloric intake, thereby inducing weight loss, by simulating, stimulating, amplifying, blocking and/or modulating signals in the gastrointestinal (GI) tract and/or nerves innervating the GI tract, to manage sensations of hunger and satiety, such as controlling hunger by signaling the gastrointestinal tract and/or gastrointestinal nerves when different hunger sensations are detected.

Abstract: Methods and devices for treating hypotension, such as in cases of shock, including septic shock and anaphylactic shock, wherein the treatment includes providing an electrical impulse to a selected region of the vagus nerve of a patient suffering from hypotension to block and/or modulate nerve signals that regulate blood pressure.

Abstract: Methods and devices for treating anaphylaxis, anaphylactic shock, bronchial constriction, and/or asthma include providing an electrical impulse to a selected region of the vagus nerve of a patient suffering from anaphylaxis to block and/or modulate nerve signals that would regulate the function of, for example, myocardial tissue, vasodilation/constriction and/or pulmonary tissue.

Abstract: Methods and devices for treating bronchial constriction related to asthma and anaphylaxis wherein the treatment includes providing an electrical impulse to a selected region of the vagus nerve and/or the lungs of a patient suffering from bronchial constriction.

Abstract: Methods for treating various health ailments that arise from dysfunction of smooth muscle associated with organ function caused by neurological malfunction wherein an appropriate signal fails to properly drive the smooth muscle wherein the treatment includes reproducing an appropriate signal and applying same either directly to the smooth muscle exhibiting the failure to respond properly, or by applying the signal to the nerves that innervate the muscles. The various treatments contemplated by this invention include, but are not limited to: acid reflux (lower esophageal sphincter), gallbladder pain, post-cholecystectomy pain, obesity, and high cholesterol (the sphincter of Oddi), pancreatic function and pancreatic pain associated with cancer (sphincter of Oddi), and asthma (the anterior and posterior pulmonary plexuses and the bronchial plexuses).

Abstract: Methods and apparatus proved for: simultaneously monitoring at least one of nerve and muscle electrical activity on respective sides of a target plexus of a patient; identifying desired electrical activity of at least one of nerves and muscles on both sides of the target plexus based on the monitored activity; and modulating the electrical activity of the at least one of nerves and muscles on both sides of the target plexus to achieve a therapeutic result.