Abstract: The present invention relates to the field of radiation therapy and methods, software and systems for image registration. According to the present invention, methods for image registration of images of a patient comprising are provided. The method may include receiving a set of image data from the patient; selecting one or more tracking regions in the set of image data, each tracking region including a tracking point or set of tracking points; receiving sets of image data captured at different times from the patient; identifying corresponding tracking regions in the sets of image data captured at different times; estimating a displacement field describing displacement vectors for a number of points in the sets of image data including the tracking regions, each displacement vector specifying a position of a region in reference to a previous position.

Abstract: The present disclosure includes procedures to automate quality assurance testing for radiotherapy equipment that includes MR-Linac devices that are agnostic as to the manufacturer and vendor of the equipment. The present disclosure includes a process for performing a validation procedure for the linear accelerator of the MR-Linac device. The present disclosure includes a process for analyzing quality of the images produced by the MR imaging device of the MR-Linac device. The present disclosure includes a process for combining performance of a validation procedure for the linear accelerator of the MR-Linac device and the analysis of the quality of the images produced by the MR imaging device of the MR-Linac device.

Abstract: Systems and methods are provided for performing operations comprising: generating a radiotherapy treatment plan for treating an ablation volume comprising a myocardial scar based on a first image of a patient that is generated using contrast-enhanced magnetic resonance (MR) imaging information; identifying, based on the first image of the patient, the ablation volume comprising the myocardial scar in a second image of the patient that is generated using MR imaging information without contrast; adjusting the radiotherapy treatment plan based on the ablation volume identified in the second image of the patient; acquiring a cine image of the patient during delivery of a radiotherapy treatment fraction by a radiotherapy treatment device based on the adjusted radiotherapy treatment plan; and comparing the cine image to the second image of the patient to control delivery of a radiotherapy beam by the radiotherapy treatment device.

Abstract: Systems and methods can include a system for positioning an ultrasound probe proximal to anatomy of a patient on an overlay on a radiation couch including a substantially planar base including engagement features to directly or indirectly index the substantially planar base to the radiation couch and a centrally located guide extending longitudinally along a top side of the base, a probe holder, configured to be coupled to, to translate longitudinally, and to be user-accessed and user-controlled from within, a central region of the substantially planar base, a clamp, configured to localize the probe holder at a specified location along a translation path in the central region of the substantially planar base, leg supports shaped to accommodate a patient's legs from behind, the pair of leg supports being shaped and arranged to provide a space therebetween that can accommodate an ultrasound probe holder.

Abstract: Systems and methods are provided for registering images. The systems and methods perform operations comprising: receiving, at a first time point in a given radiation session, a first imaging slice corresponding to a first plane; encoding the first imaging slice to a lower dimensional representation; applying a trained machine learning model to the encoded first imaging slice to estimate an encoded version of a second imaging slice corresponding to a second plane at the first time point to provide a pair of imaging slices for the first time point; simultaneously spatially registering the pair of imaging slices to a volumetric image, received prior to the given radiation session, comprising a time-varying object to calculate displacement of the object; and generating an updated therapy protocol to control delivery of a therapy beam based on the calculated displacement of the object.

Abstract: In the field of radiotherapy, methods for dose or treatment planning for a radiation therapy system having a collimator, includes determining shots to be delivered during said treatment, each shot being associated with an isocenter and being modelled by a spatial dose volume distribution of radiation, the shape of said spatial distribution depending on the specific collimator setting and said selected dose level, including selecting isocenter positions within a target in a predetermined angle range; evaluating each isocenter based on predetermined conditions; selecting at least a specific collimator and sector setting for each isocenter based on the evaluation; calculating a dose for the selected isocenters; repeating the steps until at least one stopping criteria has been reached, wherein a final set of isocenters are provided; and using the final set of isocenters in treatment planning.

Abstract: Systems and methods can include a system for positioning an ultrasound probe proximal to anatomy of a patient on a radiation couch including a substantially planar base including engagement features to directly or indirectly index the substantially planar base to the radiation couch and a centrally located guide extending longitudinally along a top side of the base, a probe holder, configured to be coupled to, to translate longitudinally, and to be user-accessed and user-controlled from within, a central region of the substantially planar base, a clamp, configured to localize the probe holder at a specified location along a translation path in the central region of the substantially planar base, leg supports shaped to accommodate a patient's legs from behind, the pair of leg supports being shaped and arranged to provide a space therebetween that can accommodate an ultrasound probe holder.

Abstract: Systems and methods can include a system for positioning an ultrasound probe proximal to anatomy of a patient on a radiation couch including a substantially planar base including engagement features to directly or indirectly index the substantially planar base to the radiation couch and a centrally located guide extending longitudinally along a top side of the base, a probe holder, configured to be coupled to, to translate longitudinally, and to be user-accessed and user-controlled from within, a central region of the substantially planar base, a clamp, configured to localize the probe holder at a specified location along a translation path in the central region of the substantially planar base, leg supports shaped to accommodate a patient's legs from behind, the pair of leg supports being shaped and arranged to provide a space therebetween that can accommodate an ultrasound probe holder.

Abstract: Systems and methods for managing motions of an anatomical region of interest of a patient during image-guided radiotherapy are disclosed. An exemplary system may include an image acquisition device, a radiotherapy device, and a processor device. The processor device may be configured to control the image acquisition device to acquire at least one 2D image. Each 2D image may include a cross-sectional image of the anatomical region of interest. The processor device may also be configured to perform automatic contouring in each 2D image to extract a set of contour elements segmenting the cross-sectional image of the anatomical region of interest in that 2D image. The processor device may be further configured to match the set of contour elements to a 3D surface image of the anatomical region of interest to determine a motion of the anatomical region of interest and to control radiation delivery based on the determined motion.

Abstract: The present invention relates to the field of radiation therapy and methods, software and systems for image registration. According to the present invention, methods for image registration of images of a patient comprising are provided. The method may include receiving a set of image data from the patient; selecting one or more tracking regions in the set of image data, each tracking region including a tracking point or set of tracking points; receiving sets of image data captured at different times from the patient; identifying corresponding tracking regions in the sets of image data captured at different times; estimating a displacement field describing displacement vectors for a number of points in the sets of image data including the tracking regions, each displacement vector specifying a position of a region in reference to a previous position.

Abstract: Systems and methods are provided for registering images. The systems and methods perform operations comprising: receiving, at a first time point in a given radiation session, a first imaging slice corresponding to a first plane; encoding the first imaging slice to a lower dimensional representation; applying a trained machine learning model to the encoded first imaging slice to estimate an encoded version of a second imaging slice corresponding to a second plane at the first time point to provide a pair of imaging slices for the first time point; simultaneously spatially registering the pair of imaging slices to a volumetric image, received prior to the given radiation session, comprising a time-varying object to calculate displacement of the object; and generating an updated therapy protocol to control delivery of a therapy beam based on the calculated displacement of the object.

Abstract: Systems and methods are provided for registering images. The systems and methods perform operations comprising: receiving, at a first time point during a given radiation session, a first imaging slice comprising an object, the first imaging slice corresponding to a first plane; accessing, at the first time point during the given radiation session, a composite imaging slice corresponding to the first plane, the composite imaging slice being generated using a plurality of imaging slices obtained prior to the first time point; spatially registering the first imaging slice and the composite imaging slice; determining movement of the object using the spatially registered first imaging slice and the composite imaging slice; and generating an updated therapy protocol to control delivery of a therapy beam based on the determined movement.

Abstract: A system for moving a patient into and from a medical apparatus includes a patient support arranged outside a treatment space of a medical apparatus, a treatment table arranged inside the treatment space in the medical apparatus and a patient bed movable in a longitudinal direction from the patient support to the treatment table and back by means of activation of a transferring mechanism. The patient bed is provided with at least a first communication channel for transferring communication signals.

Abstract: Systems and methods can include a system for positioning an ultrasound probe proximal to anatomy of a patient on a radiation couch including a substantially planar base including engagement features to directly or indirectly index the substantially planar base to the radiation couch and a centrally located guide extending longitudinally along a top side of the base, a probe holder, configured to be coupled to, to translate longitudinally, and to be user-accessed and user-controlled from within, a central region of the substantially planar base, a clamp, configured to localize the probe holder at a specified location along a translation path in the central region of the substantially planar base, leg supports shaped to accommodate a patient's legs from behind, the pair of leg supports being shaped and arranged to provide a space therebetween that can accommodate an ultrasound probe holder.

Abstract: The invention relates to a position indicator for a system for moving a patient in a non-invasive therapy system, wherein the system for moving includes a patient support arranged outside a treatment space of a medical apparatus of the non-invasive therapy system, a treatment table arranged inside the treatment space in the medical apparatus, and a patient bed movable in a longitudinal direction from the patient support to the treatment table and back by means of activation of a transferring mechanism, wherein the position indicator comprises a number of light emitting elements arranged in the patient support and each being arranged to receive activation signals instructing a receiving light emitting element to emit light to indicate positions for treatment equipment.

Abstract: In the field of radiotherapy, methods for dose or treatment planning for a radiation therapy system having a collimator, includes determining shots to be delivered during said treatment, each shot being associated with an isocenter and being modelled by a spatial dose volume distribution of radiation, the shape of said spatial distribution depending on the specific collimator setting and said selected dose level, including selecting isocenter positions within a target in a predetermined angle range; evaluating each isocenter based on predetermined conditions; selecting at least a specific collimator and sector setting for each isocenter based on the evaluation; calculating a dose for the selected isocenters; repeating the steps until at least one stopping criteria has been reached, wherein a final set of isocenters are provided; and using the final set of isocenters in treatment planning.

Abstract: A structural element for use in a radiotherapy system or a magnetic resonance imaging system or a combination of a radiotherapy system and a magnetic resonance imaging system includes a plurality of fibers and a matrix, whereby the plurality of fibers are embedded in the matrix.