Abstract: An apparatus for treating tissue in a tissue treatment region. The apparatus can comprise an electrode ring having an interior perimeter and an electrode probe having a proximal end and a distal end. The distal end of the electrode probe can be structured to axially translate relative to the interior perimeter of the electrode ring. The electrode ring and the electrode probe can be operably structured to conduct current therebetween when at least one of the electrode ring and the electrode probe is energized by an energy source. Further, the energy source can be a Radio Frequency (RF) energy source, a pulsed energy source, an irreversible electroporation energy source, or a pulsed irreversible electroporation energy source. A current from the energy source can be selected to non-thermally ablate tissue in the tissue treatment region.

Abstract: A system for stimulating the release of satiety hormone in a subject comprises a stimulus device (1) having a tissue engaging portion (2) intended to be placed in contact with a target tissue (3) of a gastrointestinal system of the subject, a movement device (15) linked with the tissue engaging portion (2) and operable to move the tissue engaging portion (2), thereby mechanically stimulating the target tissue (3), and an anchoring device for permanently fastening the stimulus device (1) in a target location at the gastrointestinal system such that the tissue engaging portion (2) engages the target tissue (3).

Abstract: An apparatus for regulating the functioning of a patient's organ or duct includes an elongated member having a first end and a second end. A fastener is disposed on the first end of the elongated member. The fastener is configured to engage the second end of the elongated member so that the elongated member forms a loop around the organ or duct. A tension element is disposed for movement within the elongated member. A drive element is associated with and engages the tension element for causing the tension element to control the tension applied by the elongated member against a patient's body organ or duct. A tension release mechanism is associated with the tension element.

Abstract: A surgical instrument comprises an articulable end effector; a drive shaft connected to the end effector that drives the end effector; an electric motor connected to the drive shaft that drives the drive shaft; a battery unit for supplying power to the electric motor; at least one sensor for sensing a status of the instrument; and an alphanumeric display located on the instrument and in communication with the at least one sensor. The alphanumeric display is for displaying alphanumeric characters that display visually to a user of the instrument a status of the instrument based on an input from the at least one sensor.

Abstract: A switch comprising an interior cavity and a switching element movably disposed within the interior cavity to define a first position and a second position, the second position being different from the first position. A biasing element imparts a biasing force to the switching element to place the switching element in either the first or the second position until an external force imparted to the switching element exceeds the biasing force, thereby causing the switching element to move to the other one of the first or the second position. A biasing force-adjusting element is cooperatively engaged with the biasing element, wherein a magnitude of the biasing force is adjustable using the biasing force-adjusting element. An electrically-conductive contact, coupled to the switching element, defines a first switching state when the switching element is in the first position and a second switching state when the switching element is in the second position.

Abstract: Provided herein are medical apparatuses and methods and more particularly devices and methods for positioning and anchoring a lining to a hollow body organ, such as a stomach, intestine or gastrointestinal tract. For example, in one embodiment, an endoluminal applier includes a fastening assembly configured to receive tissue and lining, a suction device configured to acquire tissue and lining, and a stitching mechanism configured to stitch into the fastening cavity and to apply a running suture to the tissue portion and lining.

Abstract: A surgical fastener applier having a handle and a fastener housing extending from the handle. The housing contains at least one anvil movable within the staple housing, the anvil has a proximal position and a distal position. When in the distal position a distal end of the anvil extends distal to the distal end of the staple housing. The housing contains a plurality of surgical fasteners each of which in the shape of a loop. At least one of the fasteners is placed around a portion of the anvil when in the distal position. The applier has a first mechanism for moving the anvil distally after a fastener has been deployed, and a second mechanism for moving the anvil distally after a fastener has been deployed. The second means is independent of the first means.

Abstract: A method of deploying a surgical fastener into a patient by introducing the fastener into a body of a patient while the fastener is in a first shape having a first loop with a back span and an original size and shape. The method then involves moving end segments of the fastener away from each other substantially along an entire length thereof while keeping the back span in substantially its original size and shape. The method then involves forming the fastener into a second loop having a width greater than a width of the first loop.

Abstract: A surgical instrument includes an end effector, an actuator coupled to the end effector and actuating it, a handle coupled to the end effector and having an electric motor disposed therein actuating the actuator when supplied with power, and a post-termination braking circuit including a power supply switch at the handle. The switch has a break-before-make configuration, a power-supplying state in which power is supplied to the motor, and a power-removed state in which power is not supplied to the motor. The braking circuit short-circuits power to the motor when the switch is in the power-removed state. A method for post-termination braking of the motor utilizes the permanent magnetic field to counteract inertia-induced over-stroke of the motor, drive train, and/or actuation assembly after powered operation by short-circuiting the still-spinning motor to create an electrically generated magnetic field in opposition to the permanent magnetic field upon ceasing supply of power.

Abstract: A staple cartridge comprising a cartridge body is disclosed. The cartridge body may comprise a deck and a plurality of staple cavities. The cartridge body further comprises a plurality of staples removably positioned within the staple cavities, wherein each staple is movable between an unfired position and a fired position. Each staple comprises a base, a first leg extending from the base, and a second leg extending from the base, wherein the first leg and the second leg define a plane. The base comprises an offset portion which is offset with respect to the plane when the staple is in the unfired position.

Abstract: An ultrasonic surgical instrument that has a waveguide that protrudes distally from the handpiece and a surgical tool that is configured to be coupled to the waveguide. The waveguide may have a distal end that is sized to be inserted into a cavity in a proximal end of the surgical tool and then selectively expanded to retain the distal end within the cavity to couple the surgical tool to the waveguide.

Abstract: A powered surgical instrument for cutting and fastening tissue comprises an end effector having first and second jaw members that move relatively between open and closed positions. A control circuit comprises a relay, a firing switch having first and second firing switch positions, and a clamp device that can take first and second states. The clamp device takes a second state when the jaw members are in the closed position such that the clamp device activates the relay. Upon activation of the relay, the firing switch is connected to provide power from a power supply to drive a drive system of the instrument when the firing switch is in a second firing switch position.

Abstract: Methods and devices are provided for performing various procedures using interchangeable end effectors. In general, the methods and devices allow a surgeon to remotely and selectively attach various interchangeable surgical end effectors to a shaft located within a patient's body, thus allowing the surgeon to perform various procedures without the need to remove the shaft from the patient's body. In an exemplary embodiment, multiple end effectors can be introduced into a body cavity. The end effectors can be disassociated or separate from one another such that they float within the body cavity. A distal end of a shaft can be positioned within the body cavity and it can be used to selectively engage one of the end effectors. In particular, the device can be configured to allow each end effector to be remotely attached and detached from the distal end of the shaft.

Abstract: A switch comprising a switching element, a hollow body defining an interior cavity in which the switching element is movably disposed along a longitudinal device axis to define a first and second positions along the longitudinal device axis, the second position being different from the first position, a biasing element imparting an adjustable biasing force to the switching element to place the switching element in one of the first position and the second position until an external force imparted to the switching element along the longitudinal device axis exceeds the biasing force thereby causing the switching element to move to the other one of the first position and the second position, and an electrically-conductive contact coupled to the switching element and defining a first switching state when the switching element is in the first position and a second switching state when the switching element is in the second position.

Abstract: Methods and devices are provided for activating brown adipose tissue (BAT). Generally, the methods and devices can activate BAT to increase thermogenesis, e.g., increase heat production in the patient, which over time can lead to weight loss. In one embodiment, a medical device is provided that activates BAT by electrically stimulating nerves that activate the BAT and/or electrically stimulating brown adipocytes directly, thereby increasing thermogenesis in the BAT and inducing weight loss through energy expenditure.

Abstract: The present invention relates to a surgical stapler comprising: a support base; a trigger; a handle; a retaining pin operatively connected to and extending distally from a support base, the support base being operable in the surgical stapler to cause the stapler to position staples near tissue; and a unit lockout rotatable about a pivot fixed to the handle. The unit lockout comprises an upper end near and under at least one blocking plate in the stapler; and another end facing the trigger to prevent it from firing when the upper end is blocked from upward movement by the at least one blocking plate. Whereas the upper end of the unit lockout is moved relative to the at least one blocking plate so that the upper end of unit lockout is no longer under the at least one blocking plate to permit the unit lockout to rotate about the pivot.

Abstract: An apparatus for regulating the functioning of a patient's organ or duct. The apparatus includes an elongated member having first end and second ends. A fastener is disposed on the first end of the elongated member. The fastener is configured to engage the second end of the elongated member so that the elongated member forms a ring around the organ or duct. A tension element is slidably disposed within the elongated member. A drive element is associated with and engaging the tension element for causing the tension element to control the tension applied by the elongated member against a patient's body organ or duct. An antenna/controller pod is releasably coupled to the elongated member for control of the drive element.

Abstract: Methods and devices are provided for activating brown adipose tissue with targeted substance delivery. Generally, the methods and devices can activate BAT to increase thermogenesis, e.g., increase heat production in the patient, which over time can lead to weight loss and/or improved metabolic function. In one embodiment, a chemical configured to stimulate nerves that activate the BAT and/or to stimulate brown adipocytes directly can be delivered to a patient, thereby increasing thermogenesis in the BAT and inducing weight loss and/or improved metabolic function through energy expenditure. The chemical can be delivered to the patient locally and/or systemically to stimulate the nerves and/or the brown adipocytes.

Abstract: In various embodiments, a surgical instrument is disclosed comprising a firing member, an anvil shaft assembly operably supported within an elongated shaft, and an anvil removably attachable to a distal connection portion of an anvil shaft assembly. The instrument further comprises a tissue acquisition shaft rotatably supported within the elongated shaft, tissue acquisition members pivotally attached to a distal end portion of the tissue acquisition shaft and being selectively pivotable between a retracted position to deployed positions, and at least one tissue acquisition pin corresponding to each one of the tissue acquisition members, each tissue acquisition pin radially protruding outward from the distal end portion of the tissue acquisition shaft to impale tissue drawn in towards the tissue acquisition shaft by the tissue acquisition members when the tissue acquisition members are moved from the deployed positions to the retracted position.

Abstract: A surgical instrument, such as an electrical ablation device, including a first elongate body having an insert and a second elongate body having an electrically insulative sheath that defines a bore. A mating element mates the elongate bodies when at least a portion of the insert is received within the bore. The second elongate body is configured to receive electrical energy from the first elongate body and transmit the electrical energy to an electrode. In certain embodiments, the electrical ablation device may include first and second elongate bodies. The first includes an electrically conductive insert configured to electrically couple to an energy source and apply the electrical energy to tissue, and the second includes an electrically insulative sheath defining a bore configured to receive the insert therethrough and move proximally or distally relative to the insert.