Abstract: A hand-held, electrically powered and controlled surgical stapler/cutter includes a handle shaped to fit in one hand of a user and a surgical end effector connected to the handle. The handle contains therein a selectively actuated, self-contained electric power supply having at least one battery cell, at least part of an anvil control assembly, and at least part of an electrically-powered stapler/cutter control assembly electrically connected to the power supply. The surgical end effector is operatively connected to each of the anvil control assembly and the stapler/cutter control assembly. The stapler/cutter control assembly staples and cuts tissue disposed at the surgical end effector when powered by the power supply.

Abstract: A device for guiding electrodes relative to a tissue treatment region. The device can comprise a body have a plurality of passages therethrough. Each passage can axially restrain an electrode positioned therein. When each electrode is axially restrained in a passage, the distal ends of the electrodes can be spaced a predetermined distance apart. Further, the electrodes can be held in a parallel or substantially parallel alignment when axially retained in the passages. The predetermined distance between the electrodes can correspond to a treatment distance in a tissue treatment region and the distal ends of the electrodes can be operably structured to conduct current therebetween when at least one of electrodes is energized by an energy source.

Abstract: A method for suture lacing includes providing a suture with a needle attached thereto, inserting the needle and suture into an organ through a passageway, throwing a single stitch through a first tissue member, throwing a single stitch through an opposed and spaced apart second tissue member, repeating the preceding step at least once, bringing the first and second tissue members in contact by tensioning the suture, whereby suture drag is minimized during the tensioning and even tissue compression substantially achieved, and securing the suture.

Abstract: Various methods and devices are provided for allowing multiple surgical instruments to be inserted into sealing elements of a single surgical access device. The sealing elements can be movable along predefined pathways within the device to allow surgical instruments inserted through the sealing elements to be moved laterally, rotationally, angularly, and vertically relative to a central longitudinal axis of the device for ease of manipulation within a patient's body while maintaining insufflation.

Abstract: Electrical surgical device comprising a handle shaped to be held within one hand, the handle having a self-contained power source, at least part of an end effector control assembly connected to the power source, a switch connected to the power source and operable to selectively power the end effector control assembly with the power source, and an articulation control device, wherein both the switch and the articulation control device are operated with the one hand holding the handle; an articulating connection operated by the articulation control device; and a surgical end effector connected to the handle by the articulating connection such that articulation of the surgical end effector is controlled by operation of the articulation control device and operatively connected to the end effector control assembly such that, upon operation of the end effector control assembly, the surgical end effector is operable to carry out at least one surgical procedure.

Abstract: A surgical instrument comprising a surgical end effector having an actuation assembly operable to effect a surgical procedure when actuated, a part of the actuation assembly being movable between a first position and second position, and a handle connected to the end effector for actuating the actuation assembly, the handle having a power supply disposed within the handle, a motor disposed within the handle and electrically powered by the power supply, a transmission connecting the motor to the moving part and operational to displace the moving part anywhere between the first and second positions when the motor is operated, and a manual release mechanism that selectively interrupts the transmission and, during interruption, displaces the moving part towards the first position independent of operation of the motor.

Abstract: A modular end effector delivers a therapeutic agent onto tissue that has been severed and/or stapled. The end effector is removably attached to a device. The device applies force to a piston of the end effector. The force causes a distal movement of a piston along a wall disposed within the end effector. The piston engages with agents stored on opposite sides of the wall, moving the agents distally to a mixture space. The agents are mixed in the mixture space and expelled through a tip. Staples may be embedded in or disposed below a foam block, which is disposed within a staple cartridge. Via an endoscopic stapling device, coated staples are driven through tissue while interacting with another agent on the device or the cartridge. The interaction forms a tissue restoring material that is applied onto the tissue.

Abstract: A polydioxanone film comprising substantially cylindrical polydioxanone pillars on at least one side thereof, said pillars having diameters from about 0.2 ?m to about 3 ?m, and heights from about 2 ?m to about 20 ?m from the surface of the film, a process for adsorbing proteins using the film and medical devices incorporating the film.

Abstract: A medical device is described having a handle, a shaft coupled to the handle, an end effector coupled to the shaft and an ultrasonic transducer coupled to the end effector for delivering ultrasonic energy to tissue or a vessel to be treated. A drive circuit is provided for generating a drive signal that is applied to the ultrasonic transducer. In one embodiment, the drive circuit includes a resonant circuit and a controller that varies the period of the drive signal passed through the resonant circuit in order to control the power supplied to the ultrasonic transducer.

Abstract: Endoluminal sleeve device (1) for internally lining a section of the GI tract, comprising a sleeve (2) configured for deployment inside a GI tract, the sleeve (2) having walls of a flexible material defining a sleeve lumen (3), a proximal end (4) defining a proximal lumen opening (5), and a distal end (6) defining a distal lumen opening (7), a tubular anchoring portion (8) forming said proximal lumen end (4) and defining anchoring seats (9) delimited each one by an annular collar (11) forming an opening through which adjacent tissue portions (12) can be pulled into the anchoring seats (9), expansion means adapted to act on the tissue portions (12) arranged in the anchoring seats (9) such that the tissue portions (12) expand to a dimension greater than the opening of the annular collar (11).

Abstract: A drug delivery system includes drug containers, a pump assembly, a sensor, and a controller. The drug containers each contain a different predetermined drug co-formulation of predetermined first and second drugs, wherein the first drug has a sedative effect. The sensor is adapted to sense a variable associated with the drug containers and output a different drug co-formulation identification signal associated with each of the drug containers based on the sensed variable. The controller is programmed to identify the drug co-formulation for the drug container operatively connected to the pump assembly from the associated identification signal and to control the pump assembly to deliver the drug co-formulation of the one drug container to the patient during a medical procedure according to a corresponding drug delivery algorithm which is different for each of the drug containers. A method is also disclosed which uses the drug delivery system.

Abstract: Methods and devices are provided for performing minimally invasive surgical procedures. In one embodiment, a surgical device is provided that includes an elongate shaft having a distal portion configured to be movable between a first configuration in which the distal portion of the shaft is substantially straight or linear and a second configuration in which the distal portion of the shaft is bent at a compound angle. The shaft's distal portion can be configured to be articulated in a wide range of compound angles and can be configured to be selectively locked in a fixed position anywhere within that range.

Abstract: Surgical devices and methods are described herein that provide improved motor control and feedback, thereby combining advantages of manually-operated and powered surgical devices. In one embodiment, a surgical device includes a proximal handle portion that includes a motor, a distal end effector coupled to the handle portion, and a cutting element configured to cut tissue engaged by the end effector, wherein the motor is configured to supply power that moves the cutting element. The device also includes a motor control mechanism configured to cause the amount of the power to dynamically change in response to a manual user input when the cutting element is moving.

Abstract: Methods and devices are provided for performing minimally invasive surgical procedures. In one embodiment, a surgical device is provided that include an elongate shaft having a distal portion configured to be movable between a first configuration in which the distal portion of the shaft is substantially straight or linear and a second configuration in which the distal portion of the shaft is articulated at a compound angle. The shaft's distal portion can include two articulation joints to facilitate formation of the compound angle.

Abstract: A duodenal sleeve assembly comprises a sleeve, an expandable sealing member, a tether, and an expandable anchor. The sleeve is secured to the sealing member. The tether couples the anchor with the sealing member. A deployment instrument comprises a shaft assembly, a first retention member, and a second retention member. The first retention member selectively secures the sealing member to the shaft assembly. The second retention member selectively secures the anchor to the shaft assembly. When the first retention member is released, the sealing member expands outwardly to seal the proximal end of the sleeve against the mucosa of the patient's duodenum. When the second retention member is released, the anchor expands outwardly within the stomach to anchor the sleeve assembly relative to the stomach. The tether traverses the pylorus. The sleeve isolates chyme from enzymes in the duodenum; and the mucosa of the duodenum from nutrients in the chyme.

Abstract: The present invention relates to ultrasonic surgical clamping instruments and, more particularly, to a curved clamp arm for use with ultrasonic surgical instruments that have an ultrasonically actuated blade that, in one case, is ultrasonically actuated to have motion in substantially a single plane. The curved clamp arm opens and closes with respect to the blade and also has a plane of curvature that is parallel to the plane of motion of the blade when the clamp arm is in the closed position, and not parallel to the plane of motion of the blade when the clamp arm is in the open position.

Abstract: A tissue thickness compensator comprising a first compensation layer, a second compensation layer, and a pocket situated between the compensation layers can be positioned in the end effector of a surgical instrument. A fastener cartridge positioned in the end effector can comprise a fastener moveable between an initial position and a fired position. When the fastener is moved from the initial position to the fired position, the fastener can move through the pocket and can compress a portion of the tissue thickness compensator. A support can be positioned between the first and second compensation layers. When the fastener compresses the tissue thickness compensator, at least one of the support, first compensation layer and second compensation layer can be deformed. The tissue thickness compensator can also comprise a tab and/or a limiting plate to control deformation of the compensation layers and/or the support.

Abstract: The present invention relates to a surgical stapler comprising: a support base; a trigger; a handle; a retaining pin operatively connected to and extending distally from a support base, the support base being operable in the surgical stapler to cause the stapler to position staples near tissue; and a unit lockout rotatable about a pivot fixed to the handle. The unit lockout comprises an upper end near and under at least one blocking plate in the stapler; and another end facing the trigger to prevent it from firing when the upper end is blocked from upward movement by the at least one blocking plate. Whereas the upper end of the unit lockout is moved relative to the at least one blocking plate so that the upper end of unit lockout is no longer under the at least one blocking plate to permit the unit lockout to rotate about the pivot.

Abstract: A cannula assembly including a seal for an endoscopic internal magnetic camera tether. The seal may include stacked compliant membranes with an aperture in each membrane through which a camera tether may pass. The apertures may overlap. The at least one aperture may be arranged as a slit. Each of the apertures may comprise a wedge-shaped gap. The membranes may include engagement members that couple to engagement members on the cannula assembly. The cannula assembly may provide separate ports for the camera tethers and for a trocar or other endoscopic instrument passing through the cannula assembly. The cannula assembly also may include a rotating housing with two openings and a seal arranged in each opening. The cannula assembly may include a sleeve that encases a cannula tube. The sleeve may include a seal on its end and a channel on its periphery through which a camera tether may pass.

Abstract: Disclosed is an ultrasonic surgical instrument that combines blade end-effector geometry to best affect the multiple functions of a shears-type configuration. The shape of the blade is characterized by a radiused cut offset by some distance to form a curved geometry. The cut creates a curved surface with multiple asymmetries causing multiple imbalances within the blade. Imbalance due to the curve of the instrument is corrected by a non-functional asymmetry proximal to the functional asymmetry. Imbalance due to the asymmetric cross-section of the blade is corrected by the appropriate selection of the volume and location of material removed from a functional asymmetry. The shape of the blade in one embodiment of the present invention is characterized by two radiused cuts offset by some distance to form a curved and potentially tapered geometry. These two cuts create curved surfaces including a concave surface and a convex surface.