Abstract: A method for producing a hyperpolarized sample for use in a magnetic resonance investigation has the following steps: a) providing a solid sample (50), containing long T1 nuclei and short T1 nuclei in the same molecules (51); b) hyperpolarizing the short T1 nuclei in the solid sample (50); c) transforming the solid sample (50) into a liquid sample (52); and d) transferring the polarization of the short T1 nuclei to the long T1 nuclei within the molecules in the liquid sample (52) by Cross Polarization. The method can provide samples with hyperpolarized long T1 nuclei, in particular 13C or 15N, in a simple and efficient way.

Abstract: The invention relates to substituted ullazine and analogs of ullazine as sensitizers for dye-sensitized solar cells (DSSCs) and other photoelectrochemical and/or optoelectronic devices. The sensitizers may comprise donor substituents and/or acceptor substituents, besides an anchoring group suitable for attaching the sensitizer on a semiconductor surface. DSSCs based on this type of sensitizers exhibit high power conversion efficiencies.

Abstract: Systems and methods are provided for treating a sexual disorder such as erectile dysfunction (ED) or female sexual arousal disorder (FSAD). An electrical stimulation system may include an implantable stimulation unit, an external patient controller, and an external physician controller. The implantable stimulation unit has an array of electrodes disposed on one or more flexible substrates configured to conform to a patient's anatomy at the pelvic plexus. Post-implantation, the physician controller may direct the stimulation unit to stimulate with select electrode(s) of the array to determine which electrode configuration provides optimal sexual arousal. The patient controller may be used to cause the stimulation unit to stimulate using the optimal electrode configuration at desired times.

Abstract: The invention relates to a system and a method for assessment of walking and miming gait in human. The method is preferably based on the fusion of a portable device featuring inertial sensors and several new dedicated signal processing algorithms: the detection of specific temporal events and parameters, 5 optimized fusion and de-drifted integration of inertial signals, automatic and online virtual alignment of sensors module, 3D foot kinematics estimation, a kinematic model for automatic online heel and toe position estimation, and finally the extraction of relevant and clinically meaning-full outcome parameters. Advantageously including at least one wireless inertial module attached to foot, the system provides common spatio-temporal parameters (gait cycle time, stride length, and stride velocity), with the 10 advantage of being able to work in unconstrained condition such as during turning or running.

Abstract: The present invention relates to a method, such as a surgical method for assisting a surgeon for placing screws in the spine using a robot attached to a passive structure. The present invention also related to a method, such as a surgical method for assisting a surgeon for removing volumes in the body of a patient using a robot attached to a passive structure and to a device to carry out said methods. The present invention further concerns a device suitable to carry out the methods according to the present invention.

Abstract: The present invention relates to use of inhibitors of Notch signalling pathway selected from the group consisting of 6-(4-Tert-Butylphenoxy)Pyridin-3-Amine (I3), its derivatives, in treating and/or preventing cancers.

Abstract: A database system maintains a feature set of a modern database system while operating directly on raw data files. Systems may use an adaptive indexing mechanism that maintains positional information to provide efficient access to raw data files, a flexible caching structure, and techniques for selective parsing and selective tokenizing. In doing so, possible performance bottlenecks associated with repeated parsing, tokenizing, and expensive data type conversion costs can be overcome.

Abstract: Using a transformation based at least in part on a non-simple orthogonal or unitary matrix, data may be transmitted over a data bus in a manner that is resilient to one or more types of signal noise, that does not require a common reference at the transmission and acquisition points, and/or that has a pin-efficiency that is greater than 50% and may approach that of single-ended signaling. Such transformations may be implemented in hardware in an efficient manner. Hybrid transformers that apply such transformations to selected subsets of signals to be transmitted may be used to adapt to various signal set sizes and/or transmission environment properties including noise and physical space requirements of given transmission environments.

Abstract: An encoding/decoding apparatus and method using a low-density parity-check code (LDPC code) is disclosed. Basic column group information, serving as a set of information regarding positions of rows with weight 1, is extracted from a reference column in each column group of a predetermined parity-check matrix. Column group information transforms the positions of rows with weight 1 into positions whose lengths are within a required parity length. A parity-check matrix is generated according to the generated column group information. Data is encoded or decoded based on the generated parity-check matrix.

Abstract: In this invention, we propose privacy-enhancing technologies for medical tests and personalized medicine methods, which utilize patients' genomic data. Assuming the whole genome sequencing is done by a certified institution, we propose to store patients' genomic data encrypted by a patient's public keys at a Storage and Processing Unit (SPU). A part of the corresponding private key is also stored on the SPU. At the time of the test by a Medical Unit (MU), the patient provides the second part of the private key to the MU. A test with its associated markers is determined by the MU and sent to the SPU. The test is carried out on the encrypted values thanks to homomorphic operation and returned back to the MU. The latter uses the second part of the private key to access the result.

Abstract: A method for the preparation of a sample comprising highly polarized nuclear spins is proposed, comprising at least the following steps: a) provision of molecules with 1,2-dione structural units and/or molecules with 2,5-diene-1,4-dione structural units in the solid state; b) generation of radicals from these molecules by photo induced electron transfer by a first electromagnetic irradiation in the visible or ultraviolet frequency range in the solid state; c) dynamic nuclear polarization in the presence of a magnetic field in the solid state by applying a second electromagnetic irradiation with a frequency adapted to transfer spin polarization from the electrons to the nuclear spins leading to a highly polarized state thereof. Furthermore uses of correspondingly prepared samples for NMR, MRS and MRI experiments are proposed.

Abstract: This invention describes a novel electronic device consisting of one—or more—vertically stacked gate-all-around silicon nanowire field effect transistor (SNWFET) with two independent gate electrodes. One of the two gate electrodes, acting on the central section of the transistor channel, controls on/off behavior of the channel. The second gate, acting on the regions in proximity to the source and the drain of the transistor, defines the polarity of the devices, i.e. p or n type. The electric field of the second gate acts either at the interface of the nanowire-to-source/drain region or anywhere in close proximity to the depleted region of the SiNW body, modulating the bending of the Schottky barriers at the contacts, eventually screening one type of charge carrier to pass through the channel of the transistor. This is achieved by controlling the majority carriers passing through the transistor channel by regulating the Schottky barrier thicknesses at the source and drain contacts.

Abstract: A VTOL (vertical take-off and landing) aerial flying vehicle comprising an inner frame, a gimbal system and an outer frame, the inner frame comprising a propulsion system and a control system. The propulsion system being able to generate a lift force. The VTOL may also include a decoupling mechanism having either a linear or non-linear beam coupled to a ring. The beam may optionally include sliders at ends thereof that provide an additional rotation freedom to the inner frame.

Abstract: A new gas turbine-fuel cell Hybrid Cycle is proposed. The fuel cell advantageously operates close or under atmospheric pressure and is fully integrated with the gas turbine that is based on an Inverted Brayton-Joule Cycle. The idea of the invention is to capitalize on the intrinsic oxygen-nitrogen separation characteristic of the fuel cell electrolyte by sending to the Inverted Brayton-Joule Cycle only the anodic flow, which is the one free of nitrogen. In this way the flow that expands in the turbine consists only in steam and carbon dioxide. After the expansion the steam can be easily condensed, separated and pumped up. Therefore the compressor has mainly only to compress the separated carbon dioxide. This effect generates a substantial advantage in term of efficiency and enables separating the carbon dioxide.

Abstract: New logic blocks capable of replacing the use of Look-Up Tables (LUTs) in integrated circuits, such as Field-Programmable Gate Arrays (FPGAs), are disclosed herein. In one embodiment, the new logic block is a tree structure comprised of a number of levels of cells with each cell consisting of a logic gate or the functional equivalent of a logic gate, one or more selectable inverters, and wherein the inputs of the logic block consist of the inputs to the logic gate or functional equivalent of the logic gate and inputs to the selectable inverters. The new logic blocks can map circuits more efficiently than LUTs, because they include multi-output blocks and can cover more logic depth due to the higher input and output bandwidth.

Abstract: The present invention relates to an underwater propelling device (10) i a stator (20) comprising circumferential arrayed coils (35) and being adapted to generate a controlled electromagnetic field along an axial direction, a shaftless propellant rotor (30) comprising: at least two magnetized ring-shaped plates, respectively an upper magnetized plate (31) and a lower magnetized plate (32), coaxially spaced-apart along said axial direction and perpendicular thereto such that said circumferential arrayed coils (35) are positioned therebetween, each plate (31, 32) defining a central aperture (31a, 32a) and having a circumferential array of radially extended magnetized poles (34) embedded therein, said magnetized poles (34) generating a magnetic field which interacts with the electromagnetic field of the stator (20) so as to cause the rotation of said plates (31, 32) about a central axis (ZZ?) parallel to said axial direction, at least one ring-shaped propeller (33) defined by its outer periphery and its inner

Abstract: A method for performing a post processing pattern on a diced chip having a foot-print, comprises the steps of providing a support wafer; applying a first dry film photoresist to the support wafer; positioning a mask corresponding to the footprint of the diced chip on the first dry film photoresist; expose the mask and the first dry film photoresist to UV radiation; remove the mask; photoresist develop the exposed first dry film photoresist to obtain a cavity corresponding to the diced chip; positioning the diced chip inside the cavity; applying a second dry film photoresist to the first film photoresist and the diced chip; and expose and develop the second dry film photoresist applied to the diced chip in accordance with the post processing pattern.

Abstract: The present invention relates to 4-pyrimidinylamino-benzenesulfonamide derivatives of general formula (I) and pharmaceutically acceptable salts, solvates, hydrates, regioisomeric and polymorphic forms thereof, processes for manufacturing of them, the use of them, as well as pharmaceutical compositions containing at least one of them as pharmaceutically active agent(s) together with pharmaceutically acceptable carrier, excipient and/or diluents, especially for the inhibition of polo-like kinases (PLKs) and the treatment of cancer. Said 4-pyrimidinylamino-benzenesulfonamide compounds have been also identified as new drug candidates for the prevention and/or treatment of infectious diseases like bacterial diseases e.g. tuberculosis, including the currently multidrug-resistant tuberculosis (MDR-TB), extensively drug-resistant tuberculosis (XDR-TB) as well as for preventing tuberculosis.

Abstract: A system for capturing solar light of the sun, whereby the solar light comprises a short wavelength light component and a long wavelength light component. The system comprises at least a lens (101), a light-guide (102), and a self-adaptive coupling feature (103). The at least one lens is arranged adjacent to the light-guide in order to focus the long wavelength component onto the self-adaptive coupling feature, and the self-adaptive coupling feature is configured to couple the short wavelength light component into the light-guide.

Abstract: An event-driven tracking analog to digital converter (ADC) architecture is proposed. The proposed architecture has less sensitivity to amplifier and DAC non-linearity, reduces the swing and dynamic common-mode range requirement of the operational transconductance amplifier (OTA) and comparators, respectively.