Abstract: A tissue thickness compensator may generally comprise a compressible core comprising a plurality of movable particles, and a wrap surrounding the compressible core. The plurality of movable particles may comprise at least one medicament. A tissue thickness compensator may generally comprise a compressible core comprising a plurality of crushable particles, and a wrap surrounding the compressible core. The plurality of crushable particles may comprise at least one medicament. The compressible core may comprise a material selected from a group consisting of a biocompatible material. The wrap may comprise a material selected from a group consisting of a biocompatible material. Articles of manufacture comprising the tissue thickness compensator and methods of making and using the tissue thickness compensator are also described.

Abstract: A surgical instrument is disclosed. The surgical instrument may include at least one drive system that is configured to generate control motions upon actuation thereof. At least one drive system defines an actuation axis. The surgical instrument may further include at least one interchangeable shaft assembly that is configured to be removably coupled to the at least one drive system in a direction that is substantially transverse to the actuation axis and transmit the control motions from the at least one drive system to a surgical end effector operably coupled thereto. A lockout assembly may interface with the at least one drive system for preventing actuation of the drive system unless the at least one interchangeable shaft assembly has been operably coupled to the at least one drive system.

Abstract: A surgical system includes a power supply, a connector, and a surgical instrument having a body assembly, a transmission assembly, a transducer, and a connection assembly. The connection assembly is configured to selectively electrically couple electrodes on the transducer with wires of the connector. The connection assembly may be operable in response to actuation of a trigger. Various connection assemblies include an extensible member that extends to contact an electrode, a rotatable member that rotates a contact into contact with an electrode, a solenoid that extends contacts coupled to each end of the solenoid into the electrodes, or a solenoid that translates a frame having contacts towards the electrodes. Alternatively, the surgical instrument may include a connection assembly having a slip ring and a weighted cable end. Still further, the connection assembly may include contacts on a coupleable member that may be decoupled from contacts on the transducer.

Abstract: An apparatus comprises a body, a shaft, and an end effector that is operable to compress, staple, and cut tissue. The end effector comprises and anvil and a cartridge. A longitudinal axis intersects the distal tip of the anvil when the anvil is in a closed position. The cartridge defines a sight line extending along a distal surface of the cartridge from a first side of the cartridge toward the anvil. The first side of the cartridge is opposite to the anvil. The distal surface of the cartridge is neither parallel to nor perpendicular to the longitudinal axis. The sight line intersects the longitudinal axis near the distal tip when the anvil is in the closed position. A segment of the sight line and a segment the longitudinal axis define an angle ?. The angle ? is larger than 90°.

Abstract: Various examples are directed to systems and methods comprising receiving a control signal at a control circuit of a surgical device. The control circuit may comprise a first circuit portion coupled to at least one switch operable between an open state and a closed state. The first circuit portion may be configured to communicate with a surgical generator over a conductor pair to receive the control signal and may comprise at least one resistor coupled to the at least one switch. Methods may also comprise determining the state of the at least one switch based on the value of the resistor.

Abstract: An apparatus includes a body and a shaft assembly. The shaft assembly is in communication with the body and includes an end effector, first cam gear, second cam gear, and a lock bar. The end effector has an articulation joint. The first cam gear is rotatably positioned within the shaft assembly. The second cam gear is in communication with the end effector at the articulation joint. The lock bar is distally biased to lock against the second cam gear. The first cam gear is rotatable through a first range of motion to unlock the lock bar relative to the second cam gear. The first cam gear is rotatable through a second range of motion to rotate the end effector at the articulation joint.

Abstract: Electrical surgical device comprising a handle shaped to be held within one hand, the handle having a self-contained power source, at least part of an end effector control assembly connected to the power source, a switch connected to the power source and operable to selectively power the end effector control assembly with the power source, and an articulation control device, wherein both the switch and the articulation control device are operated with the one hand holding the handle; an articulating connection operated by the articulation control device; and a surgical end effector connected to the handle by the articulating connection such that articulation of the surgical end effector is controlled by operation of the articulation control device and operatively connected to the end effector control assembly such that, upon operation of the end effector control assembly, the surgical end effector is operable to carry out at least one surgical procedure.

Abstract: In various embodiments, a staple cartridge for use with a surgical stapler is disclosed. The staple cartridge comprises a cartridge body comprising a deck, a row of first staple cavities defined in the deck, a plurality of first staples, wherein the first staples are positioned in the first staple cavities, a row of second staple cavities defined in the deck, and a plurality of second staples, wherein the second staples are positioned in the second staple cavities. The staple cartridge further comprises a first layer comprising a first portion positioned over the first staple cavities and configured to be captured within the first staples and a second portion positioned over the second staple cavities and configured to be captured within the second staples. The staple cartridge further comprises a second layer positioned over the second portion and not positioned over the first portion of the first layer.

Abstract: A surgical instrument comprising a surgical end effector, operable to effect a surgical procedure when actuated, and an actuation assembly operable to actuate said surgical end effector. The actuation assembly comprises a part operable to move between a starting position and an actuated position in which the part actuates the surgical end effector, an electrically-powered motor, a transmission mechanically connecting the motor to the part and being operable to selectively displace the part to the starting position, the actuated position, and at least one point between the starting position and the actuated position when the motor is operated, and a manual release mechanically coupled to the transmission to selectively interrupt the transmission and, during interruption, displace the part towards the starting position independent of operation of the motor.

Abstract: Methods and devices are provided for activating brown adipose tissue with targeted substance delivery. Generally, the methods and devices can activate BAT to increase thermogenesis, e.g., increase heat production in the patient, which over time can lead to weight loss and/or improved metabolic function. In one embodiment, a chemical configured to stimulate nerves that activate the BAT and/or to stimulate brown adipocytes directly can be delivered to a patient, thereby increasing thermogenesis in the BAT and inducing weight loss and/or improved metabolic function through energy expenditure. The chemical can be delivered to the patient locally and/or systemically to stimulate the nerves and/or the brown adipocytes.

Abstract: A surgical instrument comprising an end effector comprising a first jaw member defining a first longitudinal slot, a second jaw member defining a second longitudinal slot, and a first push rod member having a distally directed end pivotably coupled to the first jaw member and a proximally directed end pivotably coupled at a first pivot point. The surgical instrument additionally comprises a reciprocating member translatable distally and proximally through the first and second longitudinal slots, wherein the reciprocating member comprises a blade, a transverse element, and a first shoulder element coupled to and substantially perpendicular to the transverse element. Upon distal motion of the reciprocating member, the first shoulder element contacts the first push rod member to exert a force on at least the first jaw member causing the first jaw member to translate towards the second jaw member in a substantially parallel motion.

Abstract: An apparatus comprises a first jaw, a second jaw, a first handle, and a second handle. The second jaw is pivotally coupled with the first jaw. The first jaw and the second jaw are configured to grasp tissue. The jaws provide offset electrode surfaces that are operable to deliver bipolar RF energy to tissue grasped between the jaws. The apparatus is further operable to sever tissue. A lockout feature selectively prevents tissue severing, based on an energization state of the jaws.

Abstract: In various embodiments, an end effector for use with a surgical instrument is disclosed. The end effector comprises a first jaw and a second jaw moveable relative to the first jaw, wherein one of the first jaw and the second jaw comprises a plurality of staple cavities arranged in a plurality of curved staple cavity rows, and wherein at least one curved staple cavity row extends along a path. The path comprises a first curved portion comprising a first longitudinal vector component and a second curved portion comprising a second longitudinal vector component, wherein the second longitudinal vector component is opposite of the first longitudinal vector component. The end effector further comprises a firing member comprising a laterally-offset cutting edge, a first camming surface configured to engage the first jaw, and a second camming surface configured to engage the second jaw.

Abstract: In various embodiments, a surgical system is disclosed. The surgical system comprises a medicament and a surgical instrument comprising a plurality of staples, a cavity configured to store the medicament, a delivery passage configured to convey the medicament from the cavity to tissue, and a firing system. The firing system comprises a movable member and a firing member, wherein the firing system is configured to cooperatively move the movable member and the firing member to concurrently fire the plurality of staples and deliver at least a portion of the medicament to the tissue owing to advancement of the firing member.

Abstract: A surgical instrument can comprise a first jaw, a second jaw, and a firing system configured to be advanced relative to the first jaw and the second jaw. The firing system can comprise a firing member including a first portion configured to engage the first jaw and a second portion configured to engage the second jaw in order to position the first jaw and the second jaw relative to one another.

Abstract: A surgical instrument includes an anvil selectively coupleable to a stapling head assembly and a trigger operable to fire staples into tissue compressed between the anvil and the stapling head assembly. In some versions, a lockout member may engage a securing feature to prevent actuation of the anvil relative to the stapling head assembly. For instance, a tab may engage a slot on an actuator, a screen door lock may provide frictional resistance or engage teeth on the actuator, a door may actuate into engagement with one or more recesses, geared teeth may mesh with teeth on the actuator, the lockout member may include a ratcheting assembly to engage actuator, and/or a push button may actuate into a recess while disengaging the lockout member. Alternatively, in some versions, the trigger actuation assembly may be disengaged prior to firing. An anvil position indicator may restrict engagement of the trigger actuation assembly.

Abstract: A surgical stapler has a body, a shaft assembly extending distally from the body, and an end effector coupled with a distal end of the shaft assembly. The end effector has a stapling head assembly, an anvil, and a vacuum port. The vacuum port is operable to draw tissue between the stapling head assembly and the anvil. The anvil is operable to move toward and away from the stapling head assembly to thereby capture the tissue drawn between the stapling head assembly and the anvil. The stapling head assembly comprises a plurality of wheel assemblies and staple cartridges. At least one wheel assembly is operable to rotate to thereby move the anvil toward and away from the body. The remaining wheel assemblies are operable to rotate to thereby drive staples through the captured tissue. The body includes user input features operable to drive the wheel assemblies.

Abstract: A cuff is used to provide a form for curing fluid about the exterior of an end-to-end anastomosis site. The cuff includes a port through which fluid may be injected to reach an interior space defined between the exterior of tissue at the anastomosis site and the inner surface of the cuff. A circular stapler may be used as a mandrel for the cuff and fluid. Alternatively, inflatable balloons may be used as a mandrel. The curing fluid may comprise a mixture of fibrin and thrombin.

Abstract: A surgical stapling device comprises a handle assembly, a shaft assembly, and a stapling head assembly. The shaft assembly comprises a rotary drive shaft that translates between two longitudinal positions to alternate between a tissue clamping mode and a tissue cutting/stapling mode. The stapling head assembly includes a first set of rotary drive elements that convert rotary motion of the drive shaft into a tissue clamping action when the drive shaft is in a distal position. The stapling head assembly also includes a second set of rotary drive elements that convert rotary motion of the drive shaft into a tissue cutting/stapling action when the drive shaft is in a proximal position. The drive shaft may be driven manually or by a motor. The stapling head assembly may be provided in a cartridge form that is removable from the shaft assembly.

Abstract: In various embodiments, a surgical instrument is disclosed comprising a firing member, an anvil shaft assembly operably supported within an elongated shaft, and an anvil removably attachable to a distal connection portion of an anvil shaft assembly. The instrument further comprises a tissue acquisition shaft rotatably supported within the elongated shaft, tissue acquisition members pivotally attached to a distal end portion of the tissue acquisition shaft and being selectively pivotable between a retracted position to deployed positions, and at least one tissue acquisition pin corresponding to each one of the tissue acquisition members, each tissue acquisition pin radially protruding outward from the distal end portion of the tissue acquisition shaft to impale tissue drawn in towards the tissue acquisition shaft by the tissue acquisition members when the tissue acquisition members are moved from the deployed positions to the retracted position.