Patents Assigned to Ethicon, Inc.
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Patent number: 10736786Abstract: The present invention is directed to a flowable hemostatic paste comprising a crosslinked carboxymethyl cellulose and at least one non-toxic dispersant. More specifically the present invention relates to a hemostatic paste containing citric acid cross-linked CMC, which is suspended or dispersed as a powder in a mixture of a first non-toxic glycerol-containing hygroscopic dispersant and a second non-toxic alcohol functionalized dispersant comprising propylene glycol or 1,3-butanediol.Type: GrantFiled: August 6, 2018Date of Patent: August 11, 2020Assignees: Guangzhou Bioseal Biotech Co., Ltd., Johnson & Johnson China Ltd., Ethicon, Inc.Inventors: Dengmin Feng, Ling Teng, Yanhui Zhang, Guojun Ni, Yufu Li, Xiang Wan
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Patent number: 10729433Abstract: An applicator instrument for dispensing surgical fasteners includes a housing having an actuator and an elongated shaft extending from the housing. The applicator instrument includes a top stamping disposed within the elongated shaft, and a bottom stamping disposed within the elongated shaft that opposes the top stamping. The applicator instrument has a firing system for dispensing at least one surgical fastener from the distal end of the elongated shaft. An end cap is assembled with the distal ends of the top stamping, the bottom stamping, and the elongated shaft for stabilizing the distal end of the applicator instrument. The end cap has a distal end face with castling for engaging an opposing surface such as surgical mesh overlying tissue. The castling prevents the distal end of the applicator instrument from sliding or moving relative to the opposing surface.Type: GrantFiled: October 21, 2016Date of Patent: August 4, 2020Assignee: Ethicon, Inc.Inventors: Simon Cohn, Robert Nering, Anthony Miksza, Matthew Rohr Daniel, Jeremy David Jarrett, Richard P. Fuchs, Michael Cardinale
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Patent number: 10716548Abstract: The invention relates to syringes for storing and mixing components.Type: GrantFiled: December 1, 2016Date of Patent: July 21, 2020Assignees: Omrix Biopharmaceuticals Ltd., Ethicon, Inc.Inventors: Yair Pilpel, Sivan Doron, Yuri Zherdev, Lior Erez, Ashley DeAnglis
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Patent number: 10716558Abstract: A tissue anchor includes a plate having a top surface and a bottom surface, and an array of first pins coupled with the plate, whereby each first pin includes an elongated shaft having a lower end with a first barb facing away from the bottom surface of the plate. The plate has an array of second pin apertures that are offset from the first pins, whereby each second pin aperture has a diameter that extends from the top surface to the bottom surface of the plate. The tissue anchor includes an array of second pins extending through the second pin apertures, whereby each second pin has an elongated shaft having an upper end including a second barb facing away from the top surface of the plate and a lower end including a stop that is located below the bottom surface of the plate. The elongated shafts of the second pins have outer diameters that are smaller than the diameters of the second pin apertures for allowing the elongated shafts of the second pins to slide within the second pin apertures.Type: GrantFiled: August 4, 2017Date of Patent: July 21, 2020Assignee: Ethicon, Inc.Inventors: Julian Quintero, Leo Kriksunov
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Patent number: 10687804Abstract: An applicator instrument for dispensing surgical fasteners includes a housing, an elongated shaft, and an elongated conduit extending through the elongated shaft. A firing system is disposed within the housing. The firing system has an insertion tool having a top surface that extends proximal and distal ends thereof and a stripper ramp that projects above the top surface. An actuator activates the firing system to commence a firing cycle. During the firing cycle, the firing system drives the insertion tool toward the distal end of the elongated shaft. The elongated conduit has a top wall with a top notch formed therein. The stripper ramp slides through the top notch for guiding movement of the insertion tool as the firing system drives the insertion tool toward the distal end of the elongated shaft.Type: GrantFiled: April 21, 2017Date of Patent: June 23, 2020Assignee: Ethicon, Inc.Inventors: Mark D. Kenyon, Michael Nordmeyer, Michael Cardinale, Simon Cohn, Jianxin Guo, Doug Souls, Danial Paul Ferreira
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Patent number: 10687816Abstract: A dispensing device configured to operate with an adhesive backed mesh and backing film for tissue bonding is disclosed. The dispensing device provides for low-friction, low force pay-out of a desired length of an adhesive backed mesh to a wound site. The device prevents or eliminates distortion of the mesh prior to application to the wound site, and includes means for reducing or eliminating binding during use. The dispensing device is configured to operate in a “forward” mode (substrate to which mesh is applied passes beneath applicator after mesh is applied) to provide essentially an unobstructed view of the wound site during use.Type: GrantFiled: February 28, 2019Date of Patent: June 23, 2020Assignee: Ethicon, Inc.Inventors: John Goodman, Gregory Hake, Thomas Schoon
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Patent number: 10687986Abstract: A wound closure device and a method of its use are disclosed. The wound closure device comprises a wound closure strip, the wound closure strip comprising a wound-facing side and a top side, the wound-facing side comprises an adhesive applied over at least a portion of the wound facing side of the wound closure strip and a non-symmetric, two-part release liner assembly detachably adhered to the adhesive, the release liner assembly comprising a first section and a second section with the second section comprising a wound closure strip-free portion forming a tab. In an alternate embodiment, the device is multi-segmented and the wound closure strip may be coextensive with the release liner assembly.Type: GrantFiled: August 11, 2017Date of Patent: June 23, 2020Assignee: Ethicon, Inc.Inventor: Julian Quintero
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Patent number: 10675020Abstract: An applicator instrument for dispensing surgical fasteners includes a handle and an articulating shaft extending from the handle including proximal and distal shaft sections and an articulating joint interconnecting the proximal and distal shaft sections. The proximal shaft section has a proximal outer tube and a proximal inner member, and the distal shaft section includes a distal outer tube and a distal inner member. An incompressible member interconnects the proximal and distal inner members to form an inner shaft member having a fixed length. Distal movement of the proximal outer tube relative to the proximal inner member articulates the distal shaft section relative to the proximal shaft section via the articulating joint. As the articulating shaft moves between a straight configuration and an articulated configuration the distance between a distal-most end of the distal outer tube and the handle changes while the length of the inner shaft member remains fixed.Type: GrantFiled: June 11, 2018Date of Patent: June 9, 2020Assignee: Ethicon, Inc.Inventors: Michael Cardinale, Danial Paul Ferreira, Doug Souls, Simon Cohn, Jianxin Guo
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Patent number: 10675015Abstract: A system for deploying a suture implant includes a delivery device and a suture implant coupled with the distal end of the delivery device. The suture implant includes a suture and a slip knot that defines a suture loop, the slip knot defining a dynamic end of the suture loop that is located opposite a closed end of the suture loop. The suture implant includes a tissue anchor having first and second openings, whereby the closed end of the suture loop passes through the first and second openings for securing the tissue anchor to the suture loop. A tensioner is secured to the first end of the suture, and a pledget, located between the tensioner and the tissue anchor, is secured to the second end of the suture. Pulling the tensioner away from the tissue anchor slides the pledget and the slip knot toward the tissue anchor for shortening the length of the suture loop and reducing the distance between the pledget and the tissue anchor.Type: GrantFiled: July 12, 2017Date of Patent: June 9, 2020Assignee: Ethicon, Inc.Inventors: Jianxin Guo, Simon Cohn, Michael Cardinale
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Publication number: 20200171198Abstract: Novel, lubricious coatings for medical devices are disclosed. The coatings provide improved lubricity and durability and are readily applied in coating processes a low temperatures that do not deform the device. The present invention is also directed to a novel platinum catalyst for use in such coatings. The catalyst provides for rapid curing, while inhibiting cross-linking at ambient temperatures, thereby improving the production pot life of the coatings.Type: ApplicationFiled: November 27, 2019Publication date: June 4, 2020Applicant: Ethicon, Inc.Inventors: Duan Li Ou, Christophe Vailhe, Frank Richard Cichocki
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Publication number: 20200171520Abstract: A disposable coating applicator container for applying a coating of a therapeutic agent upon an object to be coated. The disposable coating applicator container includes a sealable container, the sealable container having a container bottom, the container bottom having upwardly extending walls, each upwardly extending wall terminating in an upper edge, and a closure for sealing a device compartment formed in part by the upwardly extending walls, the closure adjacent to the upper edges of the upwardly extending walls; and a therapeutic agent positioned in fluid communication with the device compartment, wherein the disposable coating applicator container comprises a flexible material and is in the form of a bag-like structure.Type: ApplicationFiled: November 27, 2019Publication date: June 4, 2020Applicant: Ethicon, Inc.Inventors: Frank Richard Cichocki, Robert J. Tannhauser, Leo B. Kriksunov
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Publication number: 20200172740Abstract: Novel, lubricious antimicrobial coatings for medical devices are disclosed. The coatings provide improved lubricity and durability and are readily applied in coating processes at low temperatures that do not deform the device and preserves the antimicrobial effectiveness of the antimicrobial agent. The present invention is also directed to a novel platinum catalyst for use in such coatings. The catalyst provides for rapid curing, while inhibiting cross-linking at ambient temperatures, thereby improving the production pot life of the coatings.Type: ApplicationFiled: November 27, 2019Publication date: June 4, 2020Applicant: Ethicon, Inc.Inventors: Duan Li Ou, Frank Richard Cichocki
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Publication number: 20200171209Abstract: The present disclosure provides a coating apparatus and method for applying a coating of a therapeutic agent, comprising an openable and sealable device compartment, a therapeutic agent positioned in communication with the device compartment, a thermal source for vaporizing the therapeutic agent, and a vacuum source in fluid communication with the device compartment.Type: ApplicationFiled: November 27, 2019Publication date: June 4, 2020Applicant: Ethicon, Inc.Inventors: Frank Richard Cichocki, Duan Li Ou
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Publication number: 20200171528Abstract: The present disclosure provides a coating applicator operable to apply a coating of a therapeutic agent upon an object comprising an openable and sealable device compartment, a therapeutic agent positioned in communication with the device compartment, an atomizer operable to atomize the therapeutic agent, and a source of vacuum in communication with the device compartment. The coating applicator may further comprise a drier, and the drier may comprise an arrangement to operate the source of vacuum for a time sufficient to promote drying of applied therapeutic agent. Deposition of the atomized therapeutic agent may be promoted by contacting the atomized therapeutic agent while the object is in a chilled condition and by contacting the object with atomized therapeutic agent while the atomized therapeutic agent is in a heated condition. Related methods are also disclosed.Type: ApplicationFiled: November 27, 2019Publication date: June 4, 2020Applicant: Ethicon, Inc.Inventors: Frank Richard Cichocki, Duan Li Ou
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Patent number: 10667806Abstract: An applicator instrument having a reconfigurable handle for dispensing surgical fasteners includes a housing having a proximal end and a distal end, an elongated shaft extending from the housing, a handle coupled with the proximal end of the housing, and a trigger coupled with the handle. The applicator instrument has a firing system including an energy storing assembly that is disposed within the housing, and a gear train disposed within the handle and coupled with the trigger. The trigger is squeezed for commencing a firing cycle and storing energy in the energy storing assembly. The applicator instrument includes a handle reconfiguration actuator having a first position for locking the handle in place relative to the housing and a second position for enabling the handle to rotate relative to the housing between a pistol configuration and an in-line configuration.Type: GrantFiled: April 21, 2017Date of Patent: June 2, 2020Assignee: Ethicon, Inc.Inventors: Jared Schneider, Jianxin Guo, Michael Cardinale, Simon Cohn, Mark D. Kenyon, Doug Souls, Danial Paul Ferreira, Xuelin Guo, Lindsay Epstein
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Patent number: 10667956Abstract: The invention relates to a transparent, absorbent device for the dressing of wounds and insertion sites of percutaneous and drug delivery devices. The device provides 360 degree or complete circumferential protection of a wound or insertion site of a percutaneous or drug delivery device and comprises a hydrogel center and at least one absorbent material. The hydrogel center can optionally comprise a bioactive agent(s).Type: GrantFiled: August 7, 2015Date of Patent: June 2, 2020Assignee: Ethicon, Inc.Inventors: Robert W. Van Holten, Xintian Ming, Jerome Riebman
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Patent number: 10625032Abstract: The present inventions are directed to spray tips for multidirectional or three-dimensional spraying of an unmixed two-part sealant and/or hemostat comprising a first biocompatible component and a biocompatible second component onto a tissue or wound comprising: a hollow body having inside a first component distribution compartment and a second component distribution compartment, said compartments not in fluid communication with each other. The first component can contain one or more biologic components, preferably fibrinogen and the second component can contain one or more biologic component different from the first biologic component, preferably thrombin and/or thrombin precursors. The present inventions are also directed to methods of spraying the unmixed two-part sealant or hemostat using the spray tip and associated components described above by simultaneously expressing the first component and the second component from the syringes.Type: GrantFiled: August 16, 2016Date of Patent: April 21, 2020Assignee: Ethicon, Inc.Inventors: Ashley DeAnglis, Sridevi Dhanaraj, John F. Goodman
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Patent number: 10624645Abstract: The present invention relates to surgical instruments and methods for enhancing properties of tissue repaired or joined by surgical staples and, more particularly to surgical instruments and methods designed to enhance the properties of repaired or adjoined tissue at a target surgical site, especially when sealing an anastomosis between adjacent intestinal sections so as to improve tissue viability, prevent tissue infection, and to prevent leakage. The present invention further relates to circular stapling instruments and elongated tubular hollow sleeves having compressible/expandable rings, deployed from such stapling instruments and establishing an isolated enclosure around the stapled and resected tissues at the anastomotic joint.Type: GrantFiled: September 20, 2016Date of Patent: April 21, 2020Assignee: Ethicon, Inc.Inventors: John P. Matonick, Leo B. Kriksunov, Robert J. Tannhauser
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Patent number: 10618950Abstract: Provided are methods and devices for dissolving solid protein compositions, such as solid compositions comprising fibrinogen, in an aqueous solvent. The methods comprise use of a closed container containing a volume of solid fibrinogen composition and a head space wherein the pressure within the headspace is sub-atmospheric. Aqueous solvent is introduced into the container while maintain the sub-atmospheric pressure, and subsequent to addition of the solvent, the size of the headspace is decreased to bring the pressure to atmospheric pressure. The devices are suitable for use in the disclosed method.Type: GrantFiled: December 20, 2012Date of Patent: April 14, 2020Assignees: Omrix Biopharmaceuticals Ltd., Ethicon, Inc.Inventors: Erez Ilan, Kfir Regev, Dana Leitman, Israel Nur, Moti Meron, John Goodman
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Patent number: 10610345Abstract: An applicator instrument for dispensing surgical fasteners includes an elongated shaft having a proximal shaft section and a distal shaft section. The proximal shaft section includes an outer sheath and the distal shaft section includes a segmented member moveable between straight and articulated configurations. A handle is secured to the proximal shaft section, and an actuator is provided on the handle that is coupled with the outer sheath. An articulation band is disposed within the outer sheath and extends from the handle to the segmented member. The articulation band has a proximal end coupled with the actuator and a distal end attached to the segmented member. The actuator is moveable in a first direction for retracting the outer sheath, exposing the segmented member, and applying tension to the articulation band for moving the segmented member into the articulated configuration.Type: GrantFiled: September 21, 2016Date of Patent: April 7, 2020Assignee: Ethicon, Inc.Inventors: Michael Cardinale, Simon Cohn, Jianxin Guo, Danial Paul Ferreira