Patents Assigned to Euro-Celtique, S.A.
  • 1,2,5-thiadiazol-3-YL-piperazine therapeutic agents useful for treating pain
    Patent number: 6974818
    Abstract: A compound of formula: (wherein X is O or S and R1, R3, R4, and R5 are disclosed herein) or a pharmaceutically acceptable salt thereof (a “Thiadiazolylpiperazine Compound”), pharmaceutical compositions comprising a Thiadiazolylpiperazine Compound, and methods for treating or preventing pain in a patient comprising administering to a patient in need thereof an effective amount of a Thiadiazolylpiperazine Compound are disclosed.
    Type: Grant
    Filed: February 27, 2003
    Date of Patent: December 13, 2005
    Assignee: Euro-Celtique S.A.
    Inventors: Donald J. Kyle, Qun Sun
  • Pharmaceutical compositions
    Publication number: 20050266072
    Abstract: Pharmaceutical compositions containing a therapeutically active agent, a diffusion barrier coating and coating comprising a hydrophobic material.
    Type: Application
    Filed: August 15, 2003
    Publication date: December 1, 2005
    Applicant: Euro-Celtique S.A.
    Inventors: Benjamin Oshlack, Hua-Pin Huang, Rampurna Gullapalli, Meredith Machonis
  • Method and apparatus for three dimensional imaging using infrared radiation
    Patent number: 6965108
    Abstract: An infrared three-dimensional imaging system and method in which an object is irradiated by monochromatic radiation in the near-infrared or mid-infrared region of the spectrum. A spectral image is captured for each wavelength in a spectral range by a radiation detector to create a spectral image data block that is stored on a data storage device. The object is rotated by some predetermined angular increment until a complete three hundred and sixty degree view is obtained so that a spectral image data block is created for each angular position. Each spectral image data block is compressed to its most relevant spectral information and used to re-create a three dimensional image by a known computerized tomography algorithm.
    Type: Grant
    Filed: July 30, 2001
    Date of Patent: November 15, 2005
    Assignee: Euro-Celtique, S.A.
    Inventors: Kevin C. Bynum, Abe S. Kassis
  • Gastroretentive drug delivery system comprising an extruded hydratable polymer
    Publication number: 20050249798
    Abstract: According to the present invention there is provided a pharmaceutical product for retention in the stomach. The product is produced by extrusion. The use of extrusion enables the product to take many useful forms. The product may comprise a sheet of hydratable polymer, the hydrated sheet being of a size which will not pass out of the stomach, for example a shaped sheet or a roll. The product may also comprise a sealed hollow tubular extrudate, for example a tube sealed at both ends. The product may comprise a filled capsule.
    Type: Application
    Filed: June 18, 2003
    Publication date: November 10, 2005
    Applicant: Euro-Celtique, S.A.
    Inventor: Hassan Mohammad
  • Methods for making thebaine or its acid salts
    Patent number: 6958398
    Abstract: Methods for making thebaine and an acid salt of thebaine are disclosed herein. In one embodiment, an acid salt of thebaine is made from codeinone or an acid salt of one or more of the following: 8-methoxy-?6-dihydrothebaine, codeinone dimethyl ketal, and neopinone dimethyl ketal.
    Type: Grant
    Filed: November 25, 2003
    Date of Patent: October 25, 2005
    Assignee: Euro-Celtique S.A.
    Inventors: Robert J. Kupper, Arie Gutman, Igor Rukhman, Lev Yudovich, Gennady A. Nisnevich
  • Aryl substituted thiazolidinones and the use thereof
    Patent number: 6956038
    Abstract: This invention relates aryl substituted thiazolidinones of Formula I: or a pharmaceutically acceptable salt, or solvate thereof, wherein R1 and R2, are defined in the specification. The invention is also directed to the use of compounds of Formula I for the treatment of neuronal damage following global and focal ischemia, for the treatment or prevention of neurodegenerative conditions such as amyotrophic lateral sclerosis (ALS), and for the treatment, prevention or amelioration of both acute or chronic pain, as antitinnitus agents, as anticonvulsants, and as antimanic depressants, as local anesthetics, as antiarrhythmics and for the treatment or prevention of diabetic neuropathy.
    Type: Grant
    Filed: July 16, 2002
    Date of Patent: October 18, 2005
    Assignee: Euro-Celtique S.A.
    Inventors: Qun Sun, Donald J. Kyle
  • Process for preparing oxycodone hydrochloride having less than 25 PPM 14-hydroxycodeinone
    Publication number: 20050222188
    Abstract: In certain embodiments the invention is directed to a process for preparing an oxycodone hydrochloride composition having less than 25 ppm of 14-hydroxycodeinone.
    Type: Application
    Filed: March 30, 2005
    Publication date: October 6, 2005
    Applicant: Euro-Celtique S.A.
    Inventors: Robert Chapman, Lonn Rider, Qi Hong, Donald Kyle, Robert Kupper
  • Modulation of complement to treat pain
    Publication number: 20050222027
    Abstract: The present invention provides compositions and methods for treating pain, including neuropathic pain, by modulating the expression or activity of one or more components of the complement pathway. The present invention further provides screening methods to identify therapeutic agents for treating pain by screening for compounds capable of modulating the expression or activity of one or more components of the complement pathway.
    Type: Application
    Filed: November 12, 2004
    Publication date: October 6, 2005
    Applicant: Euro-Celtique S.A.
    Inventors: Lillian Chiang, Margaret Levin
  • Formulations and methods for providing prolonged local anesthesia
    Patent number: 6921541
    Abstract: A formulation and methods for inducing sustained regional local anesthesia in a patient comprising a substrate comprising a local anesthetic and an effective amount of a biocompatible, biodegradable, controlled release material prolonging the release of the local anesthetic from the substrate to obtain a reversible local anesthesia when implanted or injected in a patient, and a pharmaceutically acceptable, i.e., non-toxic, non-glucocorticoid augmenting agent effective to prolong the duration of the local anesthesia for a time period longer than that obtainable from the substrate without the augmenting agent.
    Type: Grant
    Filed: September 9, 2002
    Date of Patent: July 26, 2005
    Assignee: Euro-Celtique S.A.
    Inventors: Mark Chasin, Paul Goldenheim, Richard Sackler, Joseph Tigner, Ronald M Burch
  • Aryl substituted pyrazoles, triazoles and tetrazoles, and the use thereof
    Patent number: 6919363
    Abstract: This invention relates to compounds having the Formula I: or a pharmaceutically acceptable salt, prodrug or solvate thereof, wherein Het and R5-R8 are set in the specification. The invention also is directed to the use of compounds of Formula I for the treatment of neuronal damage following global and focal ischemia, for the treatment or prevention of neurodegenerative conditions such as amyotrophic lateral sclerosis (ALS), and for the treatment, prevention or amelioration of both acute or chronic pain, as antitinnitus agents, as anticonvulsants, and as antimanic depressants, as local anesthetics, as antiarrhythmics and for the treatment or prevention of diabetic neuropathy.
    Type: Grant
    Filed: June 9, 2003
    Date of Patent: July 19, 2005
    Assignee: Euro-Celtique S.A.
    Inventors: Derk J. Hogenkamp, Phong Nguyen, Ji Yang
  • Medical after sales support
    Publication number: 20050119941
    Abstract: A system of providing medical after sales support to a patient or other user associated with a patient having a packaged medical product with a product code identifying the product is disclosed, wherein the user remains anonymous. A product code and a user identifier or contact address are received at a medical information computer (3) over a communications link (2,5) from a user (1,4). The received code is verified to determine if it corresponds to a valid code stored in a product code database (3e). The received user identifier/contact address is verified to determine if it corresponds to a valid user identifier/contact address stored in a user identifier/contact address database (3f). Information related to the packaged medical product identified by the product code is retrieved from a user medication record database (3h) or product information database (3g), upon positive verification.
    Type: Application
    Filed: November 27, 2002
    Publication date: June 2, 2005
    Applicant: Euro-Celtique S.A.
    Inventor: Roger James
  • Benzimidazolone compounds
    Patent number: 6872733
    Abstract: Disclosed are compounds of the formula (I): wherein A, B, C, M1-M4, R, R1, R2 and n are as described herein.
    Type: Grant
    Filed: April 18, 2002
    Date of Patent: March 29, 2005
    Assignee: Euro-Celtique S.A.
    Inventors: R. Richard Goehring, Zhengming Chen, Sam Victory, Donald Kyle
  • Aryl substituted pyrimidines
    Patent number: 6867210
    Abstract: This invention relates aryl substituted pyridines, pyrimidines, pyrazines and triazines of Formula I: or a pharmaceutically acceptable salt, prodrug or solvate thereof, wherein A1, A2, A3, R1-R4, X and Y are set in the specification. The invention is also directed to the use of compounds of Formula I for the treatment of neuronal damage following global and focal ischemia, for the treatment or prevention of neurodegenerative conditions such as amyotrophic lateral sclerosis (ALS), and for the treatment, prevention or amelioration of both acute or chronic pain, as antitinnitus agents, as anticonvulsants, and as antimanic depressants, as local anesthetics, as antiarrhythmics and for the treatment or prevention of diabetic neuropathy.
    Type: Grant
    Filed: March 12, 2001
    Date of Patent: March 15, 2005
    Assignee: Euro-Celtique S.A.
    Inventors: Derk J. Hogenkamp, Phong Nguyen, Bin Shao
  • Nociceptin analogs
    Patent number: 6867222
    Abstract: A compound of the formula (I), (II), (III) or (IV) wherein Z, A, B, C, R, R1, R2, Q, and n are as described herein.
    Type: Grant
    Filed: April 18, 2002
    Date of Patent: March 15, 2005
    Assignee: Euro-Celtique, S.A.
    Inventors: Qun Sun, R. Richard Goehring, Donald Kyle, Zhengming Chen, Sam Victory, John Whitehead
  • Container and method for dispensing transdermal dosage forms
    Patent number: 6865444
    Abstract: The present invention provides a two compartment device (10), and method of use, for the disposal of used transdermal dosage forms (26) and the dispensing of unused transdermal dosage forms (28). The first compartment (12) has a dosage form inlet (16) and a detector (20), and the second compartment (14) has a dosage form outlet (22) in communication with the detector (20). The detector (20) permits the dispensing of an unused transdermal dosage (28) form from the outlet (22).
    Type: Grant
    Filed: November 24, 2003
    Date of Patent: March 8, 2005
    Assignee: Euro-Celtique S.A.
    Inventor: Stephen Howard
  • Therapeutic agents useful for treating pain
    Patent number: 6864261
    Abstract: A compound of formula (wherein A, R1, R2, R6, m and n are disclosed herein) or a pharmaceutically acceptable salt thereof (a “Piperazine Compound”); pharmaceutical compositions comprising a Piperazine Compound; and methods for treating pain, urinary incontinence (UI), an addictive disorder, Parkinson's disease, parkinsonism, anxiety, epilepsy, stroke, a seizure, a pruritic condition, psychosis, a cognitive disorder, a memory deficit, restricted brain function, Huntington's chorea, amyotrophic lateral sclerosis (ALS), dementia, retinopathy, a muscle spasm, a migraine, vomiting, dyskinesia and depression in an animal comprising administering to an animal in need thereof an effective amount of a Piperazine Compound are disclosed.
    Type: Grant
    Filed: May 2, 2003
    Date of Patent: March 8, 2005
    Assignee: Euro-Celtique S.A.
    Inventors: Parviz Gharagozloo, Khondaker Islam, Donald J. Kyle, Qun Sun, Laykea Tafesse, John William Frank Whitehead, Ji Yang, Xiaoming Zhou
  • Nociceptin analogs
    Patent number: 6861421
    Abstract: A compound of the having the general formula (I) or general formula (II): wherein Z, A, B, C, R1, R2, Q, W, and n are as described herein.
    Type: Grant
    Filed: April 18, 2002
    Date of Patent: March 1, 2005
    Assignee: Euro-Celtique S.A
    Inventors: R. Richard Goehring, Zhengming Chen, John Whitehead, Parviz Gharagozloo, Sam Victory, Donald Kyle
  • Aryl substituted pyridines, pyrimidines, pyrazines and triazines and the use thereof
    Publication number: 20050043305
    Abstract: This invention relates aryl substituted pyridines, pyrimidines, pyrazines and triazines of Formula I: or a pharmaceutically acceptable salt, prodrug or solvate thereof, wherein A1, A2, A3, R1—R4, X and Y are set in the specification. The invention is also directed to the use of compounds of Formula I for the treatment of neuronal damage following global and focal ischemia, for the treatment or prevention of neurodegenerative conditions such as amyotrophic lateral sclerosis (ALS), and for the treatment, prevention or amelioration of both acute or chronic pain, as antitinnitus agents, as anticonvulsants, and as antimanic depressants, as local anesthetics, as antiarrhythmics and for the treatment or prevention of diabetic neuropathy.
    Type: Application
    Filed: September 29, 2004
    Publication date: February 24, 2005
    Applicant: Euro-Celtique S.A.
    Inventors: Derk Hogenkamp, Phong Nguyen, Bin Shao
  • Terazosin transdermal device & methods
    Publication number: 20050031678
    Abstract: A method of effectively treating benign prostatic hypertension in humans is achieved by administering terazosin via a transdermal formulation. Preferably, the transdermal formulation is applied to the skin of the patient and maintained in contact with the skin for at least about 24 hours, and preferably for about 3 to about 8 days.
    Type: Application
    Filed: September 20, 2004
    Publication date: February 10, 2005
    Applicant: Euro-Celtique S.A
    Inventors: Lino Tavares, Ihor Shevchuk, Mark Alfonso, Geraldine Marcenyac, Kirti Valia
  • Wireless blood glucose monitoring system
    Publication number: 20050033127
    Abstract: A system for predicting blood glucose values in a patient includes a remote wireless non-invasive spectral device, the remote wireless non-invasive spectral device generating a spectral scan of a body part of the patient. Also included are a remote invasive device and a central processing device. The remote invasive device generates a constituent value for the patient, while the central processing device predicts a blood glucose value for the patient based upon the spectral scan and the constituent value.
    Type: Application
    Filed: January 27, 2004
    Publication date: February 10, 2005
    Applicant: Euro-Celtique, S.A.
    Inventors: Emil Ciurczak, Gary Ritchie, Howard Mark, Kevin Bynum