Patents Assigned to Factor Bioscience Inc.
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Patent number: 9879228Abstract: The present invention relates in part to methods for producing tissue-specific cells from patient samples, and to tissue-specific cells produced using these methods. Methods for reprogramming cells using RNA are disclosed. Therapeutics comprising cells produced using these methods are also disclosed.Type: GrantFiled: May 25, 2017Date of Patent: January 30, 2018Assignee: FACTOR BIOSCIENCE INC.Inventors: Matthew Angel, Christopher Rohde
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Patent number: 9770489Abstract: The present invention relates in part to nucleic acids, including nucleic acids encoding proteins, therapeutics and cosmetics comprising nucleic acids, methods for delivering nucleic acids to cells, tissues, organs, and patients, methods for inducing cells to express proteins using nucleic acids, methods, kits and devices for transfecting, gene editing, and reprogramming cells, and cells, organisms, therapeutics, and cosmetics produced using these methods, kits, and devices. Methods and products for altering the DNA sequence of a cell are described, as are methods and products for inducing cells to express proteins using synthetic RNA molecules, including cells present in vivo. Therapeutics comprising nucleic acids encoding gene-editing proteins are also described.Type: GrantFiled: January 30, 2015Date of Patent: September 26, 2017Assignee: FACTOR BIOSCIENCE INC.Inventors: Matthew Angel, Christopher Rohde
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Patent number: 9758797Abstract: The present invention relates in part to nucleic acids encoding proteins, therapeutics comprising nucleic acids encoding proteins, methods for inducing cells to express proteins using nucleic acids, methods, kits and devices for transfecting, gene editing, and reprogramming cells, and cells, organisms, and therapeutics produced using these methods, kits, and devices. Methods and products for altering the DNA sequence of a cell are described, as are methods and products for inducing cells to express proteins using synthetic RNA molecules. Therapeutics comprising nucleic acids encoding gene-editing proteins are also described.Type: GrantFiled: April 13, 2017Date of Patent: September 12, 2017Assignee: FACTOR BIOSCIENCE, INC.Inventors: Matthew Angel, Christopher Rohde
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Patent number: 9695401Abstract: The present invention relates in part to methods for producing tissue-specific cells from patient samples, and to tissue-specific cells produced using these methods. Methods for reprogramming cells using RNA are disclosed. Therapeutics comprising cells produced using these methods are also disclosed.Type: GrantFiled: November 22, 2016Date of Patent: July 4, 2017Assignee: FACTOR BIOSCIENCE INC.Inventors: Matthew Angel, Christopher Rohde
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Patent number: 9657282Abstract: The present invention relates in part to nucleic acids encoding proteins, therapeutics comprising nucleic acids encoding proteins, methods for inducing cells to express proteins using nucleic acids, methods, kits and devices for transfecting, gene editing, and reprogramming cells, and cells, organisms, and therapeutics produced using these methods, kits, and devices. Methods and products for altering the DNA sequence of a cell are described, as are methods and products for inducing cells to express proteins using synthetic RNA molecules. Therapeutics comprising nucleic acids encoding gene-editing proteins are also described.Type: GrantFiled: September 20, 2016Date of Patent: May 23, 2017Assignee: FACTOR BIOSCIENCE, INC.Inventors: Matthew Angel, Christopher Rohde
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Patent number: 9605277Abstract: The present invention relates in part to nucleic acids encoding proteins, nucleic acids containing non-canonical nucleotides, therapeutics comprising nucleic acids, methods, kits, and devices for inducing cells to express proteins, methods, kits, and devices for transfecting, gene editing, and reprogramming cells, and cells, organisms, and therapeutics produced using these methods, kits, and devices. Methods for inducing cells to express proteins and for reprogramming and gene-editing cells using RNA are disclosed. Methods for producing cells from patient samples, cells produced using these methods, and therapeutics comprising cells produced using these methods are also disclosed.Type: GrantFiled: July 11, 2016Date of Patent: March 28, 2017Assignee: FACTOR BIOSCIENCE, INC.Inventors: Matthew Angel, Christopher Rohde
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Patent number: 9605278Abstract: The present invention relates in part to nucleic acids encoding proteins, nucleic acids containing non-canonical nucleotides, therapeutics comprising nucleic acids, methods, kits, and devices for inducing cells to express proteins, methods, kits, and devices for transfecting, gene editing, and reprogramming cells, and cells, organisms, and therapeutics produced using these methods, kits, and devices. Methods for inducing cells to express proteins and for reprogramming and gene-editing cells using RNA are disclosed. Methods for producing cells from patient samples, cells produced using these methods, and therapeutics comprising cells produced using these methods are also disclosed.Type: GrantFiled: July 28, 2016Date of Patent: March 28, 2017Assignee: FACTOR BIOSCIENCE INC.Inventors: Matthew Angel, Christopher Rohde
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Patent number: 9562218Abstract: The present invention relates in part to methods for producing tissue-specific cells from patient samples, and to tissue-specific cells produced using these methods. Methods for reprogramming cells using RNA are disclosed. Therapeutics comprising cells produced using these methods are also disclosed.Type: GrantFiled: June 9, 2016Date of Patent: February 7, 2017Assignee: FACTOR BIOSCIENCE INC.Inventors: Matthew Angel, Christopher Rohde
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Patent number: 9487768Abstract: The present invention relates in part to nucleic acids encoding proteins, therapeutics comprising nucleic acids encoding proteins, methods for inducing cells to express proteins using nucleic acids, methods, kits and devices for transfecting, gene editing, and reprogramming cells, and cells, organisms, and therapeutics produced using these methods, kits, and devices. Methods and products for altering the DNA sequence of a cell are described, as are methods and products for inducing cells to express proteins using synthetic RNA molecules. Therapeutics comprising nucleic acids encoding gene-editing proteins are also described.Type: GrantFiled: May 17, 2016Date of Patent: November 8, 2016Assignee: Factor Bioscience Inc.Inventors: Matthew Angel, Christopher Rohde
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Patent number: 9464285Abstract: The present invention relates in part to nucleic acids encoding proteins, therapeutics comprising nucleic acids encoding proteins, methods for inducing cells to express proteins using nucleic acids, methods, kits and devices for transfecting, gene editing, and reprogramming cells, and cells, organisms, and therapeutics produced using these methods, kits, and devices. Methods and products for altering the DNA sequence of a cell are described, as are methods and products for inducing cells to express proteins using synthetic RNA molecules. Therapeutics comprising nucleic acids encoding gene-editing proteins are also described.Type: GrantFiled: May 17, 2016Date of Patent: October 11, 2016Assignee: FACTOR BIOSCIENCE INC.Inventors: Matthew Angel, Christopher Rohde
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Patent number: 9447395Abstract: The present invention relates in part to nucleic acids encoding proteins, therapeutics comprising nucleic acids encoding proteins, methods for inducing cells to express proteins using nucleic acids, methods, kits and devices for transfecting, gene editing, and reprogramming cells, and cells, organisms, and therapeutics produced using these methods, kits, and devices. Methods and products for altering the DNA sequence of a cell are described, as are methods and products for inducing cells to express proteins using synthetic RNA molecules. Therapeutics comprising nucleic acids encoding gene-editing proteins are also described.Type: GrantFiled: April 30, 2015Date of Patent: September 20, 2016Assignee: FACTOR BIOSCIENCE INC.Inventors: Matthew Angel, Christopher Rohde
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Patent number: 9422577Abstract: The present invention relates in part to nucleic acids encoding proteins, nucleic acids containing non-canonical nucleotides, therapeutics comprising nucleic acids, methods, kits, and devices for inducing cells to express proteins, methods, kits, and devices for transfecting, gene editing, and reprogramming cells, and cells, organisms, and therapeutics produced using these methods, kits, and devices. Methods for inducing cells to express proteins and for reprogramming and gene-editing cells using RNA are disclosed. Methods for producing cells from patient samples, cells produced using these methods, and therapeutics comprising cells produced using these methods are also disclosed.Type: GrantFiled: June 4, 2014Date of Patent: August 23, 2016Assignee: FACTOR BIOSCIENCE INC.Inventors: Matthew Angel, Christopher Rohde
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Patent number: 9399761Abstract: The present invention relates in part to methods for producing tissue-specific cells from patient samples, and to tissue-specific cells produced using these methods. Methods for reprogramming cells using RNA are disclosed. Therapeutics comprising cells produced using these methods are also disclosed.Type: GrantFiled: July 27, 2015Date of Patent: July 26, 2016Assignee: FACTOR BIOSCIENCE INC.Inventors: Matthew Angel, Christopher Rohde
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Patent number: 9376669Abstract: The present invention relates in part to nucleic acids encoding proteins, therapeutics comprising nucleic acids encoding proteins, methods for inducing cells to express proteins using nucleic acids, methods, kits and devices for transfecting, gene editing, and reprogramming cells, and cells, organisms, and therapeutics produced using these methods, kits, and devices. Methods and products for altering the DNA sequence of a cell are described, as are methods and products for inducing cells to express proteins using synthetic RNA molecules. Therapeutics comprising nucleic acids encoding gene-editing proteins are also described.Type: GrantFiled: June 10, 2015Date of Patent: June 28, 2016Assignee: FACTOR BIOSCIENCE INC.Inventors: Matthew Angel, Christopher Rohde
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Patent number: 9127248Abstract: The present invention relates in part to methods for producing tissue-specific cells from patient samples, and to tissue-specific cells produced using these methods. Methods for reprogramming cells using RNA are disclosed. Therapeutics comprising cells produced using these methods are also disclosed.Type: GrantFiled: June 28, 2013Date of Patent: September 8, 2015Assignee: Factor Bioscience Inc.Inventors: Matthew Angel, Christopher Rohde
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Publication number: 20140356906Abstract: The present invention relates in part to nucleic acids encoding proteins, nucleic acids containing non-canonical nucleotides, therapeutics comprising nucleic acids, methods, kits, and devices for inducing cells to express proteins, methods, kits, and devices for transfecting, gene editing, and reprogramming cells, and cells, organisms, and therapeutics produced using these methods, kits, and devices. Methods for inducing cells to express proteins and for reprogramming and gene-editing cells using RNA are disclosed. Methods for producing cells from patient samples, cells produced using these methods, and therapeutics comprising cells produced using these methods are also disclosed.Type: ApplicationFiled: June 4, 2014Publication date: December 4, 2014Applicant: FACTOR BIOSCIENCE INC.Inventors: Matthew Angel, Christopher Rohde
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Publication number: 20130344602Abstract: The present invention relates in part to methods for producing tissue-specific cells from patient samples, and to tissue-specific cells produced using these methods. Methods for reprogramming cells using RNA are disclosed. Therapeutics comprising cells produced using these methods are also disclosed.Type: ApplicationFiled: June 28, 2013Publication date: December 26, 2013Applicant: Factor Bioscience, Inc.Inventors: Matthew Angel, Christopher Rohde
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Patent number: 8497124Abstract: The present invention relates in part to methods for producing tissue-specific cells from patient samples, and to tissue-specific cells produced using these methods. Methods for reprogramming cells using RNA are disclosed. Therapeutics comprising cells produced using these methods are also disclosed.Type: GrantFiled: May 7, 2012Date of Patent: July 30, 2013Assignee: Factor Bioscience Inc.Inventors: Matthew Angel, Christopher Rohde