Patents Assigned to Foundation
  • Patent number: 9006452
    Abstract: Provided is a two-photon fluorescent probe, and more particularly, a two-photon fluorescent probe which is one or more selected from compounds represented by Formulae 1 and 2, a method for manufacturing the same, and an imaging method of zinc ions within the mitochondrion using the same. Since two probes are introduced into one molecule, the two-photon fluorescent probe of the present invention can selectively dye the mitochondria, simultaneously with reacting with zinc ions, thereby generating intense fluorescence. Thus, the two-photon fluorescent probe of the present invention can be used for the imaging of zinc ion distribution and activation within the mitochondrion in living cells or intact biological tissues.
    Type: Grant
    Filed: October 18, 2011
    Date of Patent: April 14, 2015
    Assignee: AJOU University Industry-Academic Cooperation Foundation
    Inventor: Hwan Myung Kim
  • Patent number: 9005267
    Abstract: An endovascular delivery system includes an endovascular prosthetic device and a signal active guide wire engaging the endovascular prosthetic device. A rotary encoder is coupled with the guide wire and the endovascular prosthetic device to provide an encoder signal on the guide wire. The encoder signal is indicative of axial angular position of the endovascular prosthetic device during implantation of the endovascular prosthetic device in a body of a patient.
    Type: Grant
    Filed: April 24, 2012
    Date of Patent: April 14, 2015
    Assignee: Cleveland Clinic Foundation
    Inventors: Roy K. Greenberg, Karl J. West, Vikash Ravi Goel
  • Patent number: 9005917
    Abstract: The present invention relates to a two-photon fluorescent probe, more particularly a two-photon fluorescent probe represented by Formula 1, a method for preparing same and a method for imaging thiols in mitochondria using same. The two-photon fluorescent probe according to the present invention, having two probes introduced in one molecule, can selectively dye mitochondria and emit intense fluorescence by reacting with thiols. Accordingly, it can be used to image the distribution and activation of thiols in a living cell or an intact living tissue.
    Type: Grant
    Filed: October 17, 2011
    Date of Patent: April 14, 2015
    Assignee: Ajou University Industry-Academic Cooperation Foundation
    Inventor: Hwan Myung Kim
  • Patent number: 9007369
    Abstract: A method for photogrammetric texture mapping using casual images is provided. The method may include the following steps: estimating, for each vertex of at least a portion of a three dimensional (3D) mesh representing a model, projection parameters associated with a virtual camera that is unique for each vertex; mapping pixels from a two dimensional (2D) image to the vertices, such that each mapping of a pixel is based on the estimated respective virtual camera parameters; and texturing the portion of the mesh with corresponding mapped pixels wherein vertices on the textured portion are selected such that they are visible from a specified viewpoint associated with the 3D mesh.
    Type: Grant
    Filed: September 10, 2013
    Date of Patent: April 14, 2015
    Assignee: Technion Research and Development Foundation Ltd.
    Inventors: Yochay Tzur, Ayellet Tal
  • Patent number: 9008512
    Abstract: An Optical Access Network, a Optical Network Unit (ONU) and various methods for exchanging information are provided.
    Type: Grant
    Filed: June 22, 2011
    Date of Patent: April 14, 2015
    Assignees: Technion Research and Development Foundation Ltd., Yissum Research Development Company of the Hebrew University of Jerusalem Ltd
    Inventors: Moshe Nazarathy, Amos Agmon, Dan M. Marom
  • Patent number: 9007039
    Abstract: Provided is a single inductor multiple output (SIMO) direct current-to-direct current (DC/DC) converter that may perform DC/DC conversion by transferring, to output nodes, input current that is input and thereby stored in a single inductor. An output selection unit of the SIMO DC/DC converter may select, from output nodes, a first output node to be supplied with current from a driving unit, and provide output voltage of the first output node and reference voltage of the first output node to a hysteresis comparison unit. The hysteresis comparison unit may control on-time and/or inductor peak current by determining whether the output voltage of the first output node is higher than the reference voltage of the first output node by at least a first threshold, and whether the output voltage of the first output voltage is lower than the reference voltage of the first output voltage by at least a second threshold.
    Type: Grant
    Filed: June 13, 2012
    Date of Patent: April 14, 2015
    Assignee: Korea University Research and Business Foundation
    Inventors: Chul Woo Kim, Jung Moon Kim
  • Patent number: 9006394
    Abstract: The present invention relates to methods of growing and maintaining pluripotent cells on an insoluble substrate that presents a peptide that binds to glycosaminoglycans, such as heparin. Specifically, methods of growing and maintaining pluripotent cells on substrates having a chemically defined surface presenting at least one peptide having basic amino acid residues separated by one or two hydrophobic amino acid residues.
    Type: Grant
    Filed: January 23, 2014
    Date of Patent: April 14, 2015
    Assignee: Wisconsin Alumni Research Foundation
    Inventors: Laura Lee Kiessling, Joseph R. Klim, Lingyin Li
  • Patent number: 9007269
    Abstract: Embodiments of the invention provide a dielectric waveguide antenna including a dielectric waveguide transmitting a signal applied from a power feeder, a dielectric waveguide radiator radiating the signal transmitted from the dielectric waveguide to the air through a first aperture, and a matching unit formed in a portion of the dielectric waveguide and controlling a serial reactance and a parallel reactance to thereby perform impedance matching between the dielectric waveguide radiator and the air, in order to reduce reflection generated in the first aperture during the radiation of the signal through the first aperture. Reflection in the aperture is reduced through the matching unit having various structures, thereby making it possible to improve characteristics of the dielectric waveguide antenna.
    Type: Grant
    Filed: February 20, 2014
    Date of Patent: April 14, 2015
    Assignees: Samsung Electro-Mechanics Co., Ltd., Korea University Research and Business Foundation
    Inventors: Jung Aun Lee, Myeong Woo Han, Chul Gyun Park, Moonil Kim, Seung Ho Choi, Kook Joo Lee
  • Patent number: 9005662
    Abstract: An article comprising a polyelectrolyte complex comprising an interpenetrating network of at least one predominantly positively charged polyelectrolyte polymer and at least one predominantly negatively charged polyelectrolyte polymer, the polyelectrolyte complex further comprising a plurality of closed-shell pores, the plurality of pores having at least one average transverse dimension between about 100 nanometer and about 1000 micrometers.
    Type: Grant
    Filed: August 19, 2010
    Date of Patent: April 14, 2015
    Assignee: The Florida State University Research Foundation, Inc.
    Inventor: Joseph B. Schlenoff
  • Patent number: 9005540
    Abstract: Hollow conjugated polyelectrolyte (HCPE) microcapsules contain at least one conjugated polyelectrolyte and at least one other polyelectrolyte of complementary charge and the microcapsule has a hollow core. The conjugated polyelectrolyte is a polymer with a multiplicity of charged repeating units where a portion of the charged repeating units form a pi-conjugated sequence. The complementary polyelectrolyte is a polymer with a complementary charged repeating unit to the charged repeating units of the conjugated polyelectrolyte. The HCPE microcapsules can be formed by successively coating a sacrificial core with alternating layers of complementary polyelectrolytes, at least one of which is a conjugated polyelectrolyte. The sacrificial core can be removed to form the hollow center of a HCPE microcapsule.
    Type: Grant
    Filed: November 27, 2013
    Date of Patent: April 14, 2015
    Assignees: University of Florida Research Foundation, Inc., STC.UNM
    Inventors: Kirk S. Schanze, Motokatsu Ogawa, Jonathan Robert Sommer, David G. Whitten, Thomas S. Corbitt
  • Patent number: 9005665
    Abstract: Disclosed herein are methods and compositions for treating or preventing Porcine reproductive and respiratory syndrome (PRRS) infection in a subject.
    Type: Grant
    Filed: April 24, 2013
    Date of Patent: April 14, 2015
    Assignee: Ohio State Innovation Foundation
    Inventors: Renukaradhya Gourapura, Varun Dwivedi, Basavaraj Binjawadagi, Jordi Torrelles
  • Patent number: 9008781
    Abstract: Effective systems and methods for improving neural communication impairment of a vertebrate being and affecting motor activity of a peripheral body part including a first signal providing component configured to provide pulsed peripheral stimulation signals at the peripheral body part, a second signal providing component configured to provide a pulsed motor cortex stimulation signal to a motor cortex area, a substantially DC signal providing component configured to provide direct current spinal stimulation signal at a neural spinal junction and a controller component configured to control timing of the pulsed peripheral stimulation signals and the pulsed motor cortex stimulation signal.
    Type: Grant
    Filed: March 7, 2014
    Date of Patent: April 14, 2015
    Assignee: The Research Foundation of the City University of New York
    Inventor: Zaghloul Ahmed
  • Patent number: 9006173
    Abstract: This invention relates to the use of microcystins as agents for treatment of cancer. Also provided are methods of screening for microcystins with improved cytotoxicity.
    Type: Grant
    Filed: May 10, 2007
    Date of Patent: April 14, 2015
    Assignee: University of Kentucky Research Foundation
    Inventors: Noel R. Monks, Shuqian Liu, Jeffrey A. Moscow
  • Patent number: 9006183
    Abstract: The use of lipopeptides as inducers of NF-?B for the protection of mammals from the effects of apoptosis is described.
    Type: Grant
    Filed: July 15, 2013
    Date of Patent: April 14, 2015
    Assignees: Cleveland Clinic Foundation, Cleveland BioLabs, Inc.
    Inventors: Alexander Shakhov, Andrei Gudkov
  • Patent number: 9004752
    Abstract: A viable strategy to enhance the bioavailability of poorly soluble drugs is to use amorphous solids in place of the more commonly used crystalline solids in pharmaceutical formulations. However, amorphous solids are physically meta-stable and tend to revert back to their crystalline counterpart. An effective approach to stabilizing an amorphous drug against crystallization is to disperse it in a polymer matrix. The drug's solubility in the chosen polymer defines the upper limit of drug loading without any risk of crystallization. Measuring the solubility of a drug in a polymer has been a scientific and technological challenge because the high viscosity of polymers makes achieving solubility equilibrium difficult and because pharmaceutically important drug/polymer dispersions are glasses, which undergo structural relaxation over time. The invention provides a method based on Differential Scanning calorimetry (DSC) for measuring the solubility of crystalline drugs in polymeric matrices.
    Type: Grant
    Filed: April 29, 2009
    Date of Patent: April 14, 2015
    Assignees: Abbvie, Inc., Abbvie Deutschland GmbH & Co KG, Wisconsin Alumni Research Foundation
    Inventors: Geoff G. Zhang, Lian Yu, Jing Tao, Ye Sun, Markus Maegerlein
  • Patent number: 9006473
    Abstract: Described herein are nitrated lipids and methods of making and using the nitrated lipids.
    Type: Grant
    Filed: October 8, 2012
    Date of Patent: April 14, 2015
    Assignees: The UAB Research Foundation, The State of Oregon Acting By and Through the State Board of Higher Education on Behalf of The University of Oregon, University College Cardiff Consultants Limited, Morehouse School of Medicine, Inc.
    Inventors: Bruce A. Freeman, Francisco Schopfer, Valerie O'Donnell, Paul Baker, Yuqing E. Chen, Bruce Branchaud
  • Patent number: 9005425
    Abstract: Methods, systems, and compounds for detecting modified nucleic acid bases are disclosed and described. The methods provide for detecting a nucleic acid lesion and can include directing a nucleic acid adduct into a channel, wherein the nucleic acid adduct includes a nucleic acid having a lesion and a current modulating compound coupled to the nucleic acid at the lesion (110), and measuring a change in current through the channel in response to the current modulating compound to detect the lesion (112). The method can optionally include forming the nucleic acid adduct. Also provided is a method for identifying the number of repeat nucleotides in at least a portion of a nucleic acid strand, a method of assigning a registration marker within a nucleic acid, and a method of obtaining sequence information from a nucleic acid comprising assigning a registration marker on the nucleic acid.
    Type: Grant
    Filed: September 7, 2011
    Date of Patent: April 14, 2015
    Assignee: University of Utah Research Foundation
    Inventors: Cynthia J. Burrows, Henry S. White, Ryuji Kawano, Aaron M. Fleming, Na An
  • Patent number: 9005994
    Abstract: The present application pertains to improved methods of detecting biomolecules in a biological sample (or system), In particular, embodiments discussed herein allow for the detection of biomolecule complexes. The embodiments enable for the first time the elucidation of the significance of biomolecule complexes for certain disease states, which in turn enables the diagnosis of disease states based on the identity and complexing level of a biomolecule complex in a particular biological sample.
    Type: Grant
    Filed: January 12, 2011
    Date of Patent: April 14, 2015
    Assignee: University of Central Florida Research Foundation, Inc.
    Inventor: Qun Huo
  • Patent number: 9006428
    Abstract: The present invention relates to high transmission green dye for LCD, dye dispersion comprising the dye, coloring composite comprising the dye dispersion, color filter comprising the coloring composite, and synthetic method thereof.
    Type: Grant
    Filed: December 31, 2012
    Date of Patent: April 14, 2015
    Assignees: LG Display Co., Ltd., Seoul National University R&DB Foundation
    Inventors: YoungHoon Kim, JiChul Lim, ByungGun Ahn, SangHun Han, JaePil Kim, SeHun Kim, Jun Choi, JinWoong Namgoong
  • Patent number: 9006752
    Abstract: Embodiments of the invention pertain to a method and apparatus for sensing infrared (IR) radiation. In a specific embodiment, a night vision device can be fabricated by depositing a few layers of organic thin films. Embodiments of the subject device can operate at voltages in the range of 10-15 Volts and have lower manufacturing costs compared to conventional night vision devices. Embodiments of the device can incorporate an organic phototransistor in series with an organic light emitting device. In a specific embodiment, all electrodes are transparent to infrared light. An IR sensing layer can be incorporated with an OLED to provide IR-to-visible color up-conversion. Improved dark current characteristics can be achieved by incorporating a poor hole transport layer material as part of the IR sensing layer.
    Type: Grant
    Filed: February 10, 2014
    Date of Patent: April 14, 2015
    Assignee: University of Florida Research Foundation, Inc.
    Inventors: Franky So, Do Young Kim