Abstract: Methods, systems, and compounds for detecting modified nucleic acid bases are disclosed and described. The methods provide for detecting a nucleic acid lesion and can include directing a nucleic acid adduct into a channel, wherein the nucleic acid adduct includes a nucleic acid having a lesion and a current modulating compound coupled to the nucleic acid at the lesion (110), and measuring a change in current through the channel in response to the current modulating compound to detect the lesion (112). The method can optionally include forming the nucleic acid adduct. Also provided is a method for identifying the number of repeat nucleotides in at least a portion of a nucleic acid strand, a method of assigning a registration marker within a nucleic acid, and a method of obtaining sequence information from a nucleic acid comprising assigning a registration marker on the nucleic acid.

Abstract: Described herein are nitrated lipids and methods of making and using the nitrated lipids.

Abstract: The methods and systems of the present invention is an algorithm which estimates motion inside objects that change during the scan. The algorithm is flexible and can be used for solving the misalignment correction problem and, more generally, for finding scan parameters that are not accurately known. The algorithm is based on Local Tomography so it is faster and is not limited to a source trajectory for which accurate and efficient inversion formulas exist.

Abstract: The present invention relates to a novel fusion protein comprising Staphylococcal protein A and mussel adhesive protein, a biochip comprising a solid substrate to which the fusion protein is attached, and a method for detecting a target antigen in a biological sample using the biochip. Furthermore, the present invention relates to a polynucleotide encoding the fusion protein, a recombinant vector comprising the polynucleotide, a transformed cell comprising the recombinant vector, and a method of preparing the fusion protein by transformed cell comprising the recombinant vector.

Abstract: Embodiments of the invention are directed to Ge comprising heterocyclic compounds which can be used for the preparation of homopolymers and copolymers. The copolymers can be donor-acceptor (DA) alternating copolymers where the donor unit is a Ge comprising heterocyclic unit. The polymers can be used as materials in solar cells and other photovoltaic devices, transistors, diodes, light emitting devices (LEDs), conductors, supercapacitors, batteries, and electrochromic devices.

Abstract: The invention relates to microRNA mimics, corresponding to the miR-15/107 family, and to methodology for using microRNA mimics to treat malignant pleural mesothelioma (MPM) by restoring regulation of the expression of target genes of the miR-15/107 family in MPM tumor cells.

Abstract: The invention provides methods, compositions, and devices for promoting adhesion or migration of endothelial cells.

Abstract: A capsule configured for in vivo refilling of a therapeutic agent. In certain embodiments, the capsule may contain methotrexate.

Abstract: This document provides methods and materials that can be used to replace a circumferential segment of an esophagus. For example, methods and materials that can be used to provide a tubular connection from one stump end of an esophagus to another stump end of the esophagus are provided.

Abstract: There is provided a capacitor sensor capable of controlling sensitivity, wherein the capacitor sensor measures the magnitude and direction of a shear force applied to the sensor, as well as the magnitude of a normal force applied on the surface of the sensor, and consists of a single cell including a pattern electrode capable of varying its shape to control the sensitivity of the sensor.

Abstract: A spring-type brake actuator for a pneumatically-operated vehicle brake is provided, in which the parking brake release piston is formed from at least one stamped actuator piston plate, preferably a stamped aluminum plate. Preferably the biasing force of the power spring of the spring brake actuator bears on a stamped spring seat cap element which is interposed between the power spring and the stamped actuator piston plate. In addition, the parking brake release piston flexible diaphragm may be captured between the stamped actuator piston plate and a stamped backing plate by affixing the backing plate to a joining member, where the joining member includes a threaded insert to receive a manually-actuated parking brake release actuation tool.

Abstract: Provided herein methods for determining whether a subject, particularly a human subject, is at risk of developing, having, or experiencing a complication of cardiovascular disease, and methods of treating subjects who are identified by the current methods of being at risk for cardiovascular disease. In one embodiment, the method comprises determining levels of one or more oxidized apolipoprotein A-I related biomolecules in a bodily sample from the subject. Also, provided are kits and reagents for use in the present methods. Also provided are methods for monitoring the status of cardiovascular disease in a subject or the effects of therapeutic agents on subjects with cardiovascular disease. Such method comprising determining levels of one or more oxidized apolipoprotein A-I related molecules in bodily samples taken from the subject over time or before and after therapy.

Abstract: An interference signal avoiding device of a frequency hopping spread system and a method thereof are disclosed. A method of transmitting/receiving an interference signal avoiding signal according to the present invention includes: determining a frequency hopping channel set and a parameter of an interference signal detector in consideration of characteristics of an interference signal; detecting whether there is an interference signal with respect to frequency hopping candidate channels that are to be used for the next frequency hopping by using the determined interference signal detector; transmitting a signal through a channel that is determined by the interference signal detector that there is no interference signal among the frequency hopping candidate channels; and searching a channel through which the signal is transmitted from the frequency hopping candidate channels in order to receive the transmitted signal.

Abstract: Disclosed is a method and apparatus for collision avoidance in a sensor network. The method includes transmitting data by a transmitter; comparing, by the transmitter, a remaining time between the data transmission and a backoff period with a turnaround time taken for the transmitter to switch from a transmit (Tx) mode to a receive (Rx) mode; selectively transmitting, by the transmitter, a busy signal indicating that a channel is in use, according to the comparison result; and receiving, by the transmitter, an acknowledgement (ACK) signal from a receiver after the turnaround time has elapsed.

Abstract: An apparatus and method for nanopatterning of substrates using the demagnified Talbot effect, wherein: (a) large arrays of nanostructures can rapidly be printed; (b) short extreme ultraviolet wavelengths permits sub-100 nm spatial resolution; (c) the de-magnification factor can be continuously adjusted, that is, continuously scaled; (d) the patterning is the effect of the collective diffraction of numerous tiled units that constitute the periodic array, giving rise to error resistance such that a defect in one unit is averaged over the area of the mask and the print does not show any defects; (e) the Talbot mask does not wear out since the method is non-contact; and (f) the feature sizes on the mask do not have to be as small as the feature sizes desired on the target, are described. The apparatus includes a source of coherent radiation having a chosen wavelength directed onto a focusing optic, the reflected converging light passing through a Talbot mask and impinging on a target substrate.

Abstract: The present invention relates to treating a tissue in a mammal from the effects of reperfusion using flagellin.

Abstract: The current invention is a capture-particle comprising: a) a molecular sieve portion; and b) an analyte binding portion; wherein the molecular sieve portion, analyte binding portion or both further comprise a cross-linked region having modified porosity. Capture particles wherein the molecular sieve portion, analyte binding portion or both comprise pore dimensions sufficient to exclude molecules larger than about 60 kDa. These particles are useful in purification and diagnostic methods. Kits comprising the capture particles are also described.

Abstract: An intensity modulator for controlling the intensity of ions, such as protons, controllably block a portion of sub-areas of an area beam to control the average intensity within that sub-area. A fan beam is then created by a focusing process that reforms the area beam while blurring intensity variations in each sub-area to a corresponding beamlet in the fan beam of uniform intensity.

Abstract: The present invention relates to preparation and application of a temperature-sensitive polyethylene glycol/polyester block copolymer having a bioactive functional group introduced into a side chain thereof. More specifically, it relates to a temperature-sensitive polyethylene glycol/polyester block copolymer including a lactide segment having a bioactive functional group introduced into a side chain thereof and a method for preparing same. The temperature-sensitive polyethylene glycol/polyester block copolymer according to the present invention having a bioactive functional group introduced into a side chain thereof can be widely used as a drug delivery system, a support for tissue engineering, an adhesion inhibitor, etc.

Abstract: This document provides methods and materials related to Prevotella histicola preparations. For example, Prevotella histicola preparations in the form of an oral medicament or dietary supplement (e.g., a pill, tablet, capsule) are provided. In addition, methods and materials for using a Prevotella histicola preparation provided herein as an anti-inflammatory agent are provided.