Patents Assigned to Foundation
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Patent number: 8951741Abstract: Embodiments of the presently-disclosed subject matter provide an isolated polypeptide comprising the sequence of SEQ ID NO: 1, fragments thereof, and/or epitopes thereof. Embodiments of the presently-disclosed subject matter also provide methods for diagnosing a Strongylus vulgaris infection in a subject that comprises providing a biological sample from the subject and contacting the sample with the present isolated polypeptide, fragment thereof, and/or epitope thereof. In some embodiments the Strongylus vulgaris infection can be detected during a prepatent period. In further embodiments the subject is a horse.Type: GrantFiled: October 29, 2013Date of Patent: February 10, 2015Assignee: University of Kentucky Research FoundationInventors: Martin Nielsen, Ulla Anderson, Daniel Howe
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Patent number: 8951737Abstract: Use of antibodies or binding portions thereof, probes, ligands, or other biological agents which either recognize an extracellular domain of prostate specific membrane antigen (PSMA) or bind to and are internalized with PSMA. These biological agents can be labeled and used for detection of cancerous tissues, particularly cancerous tissues proximate to or containing vascular endothelial cells, which express an extracellular domain of PSMA. The labeled biological agents can also be used to detect normal, benign hyperplastic, and cancerous prostate epithelial cells or portions thereof. They also can be used alone or bound to a substance effective to ablate or kill such cells as a therapy for prostate or other cancers. Also disclosed are four hybridoma cells lines, each of which produces a monoclonal antibody recognizing extracellular domains of PSMA of normal, benign hyperplastic, and cancerous prostate epithelial cells or portions thereof.Type: GrantFiled: November 13, 2007Date of Patent: February 10, 2015Assignee: Cornell Research Foundation, Inc.Inventor: Neil H. Bander
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Patent number: 8951762Abstract: A method of increasing production of fatty acids comprising introducing into a host cell or organism and expressing therein an acyl-acyl carrier protein (ACP) thioesterase (TE) from Bryantella formatexigens or a mutant thereof; a method of making a mutant B. formatexigens acyl-ACP TE; a method of making a chimeric Cuphea viscosissima acyl-ACP TE; a nucleic acid encoding a mutant acyl-ACP TE or a chimeric C. viscosissima acyl-ACP TE; a host cell or organism comprising the nucleic acid; a mutant acyl-ACP TE or chimeric C. viscosissima acyl-ACP TE; a method of altering the specificity of a plant acyl-ACP TE; and a method of altering the level of activity of a plant acyl-ACP TE.Type: GrantFiled: July 25, 2012Date of Patent: February 10, 2015Assignee: Iowa State University Research Foundation, Inc.Inventors: Basil J. Nikolau, Marna Yandeau-Nelson, Fuyuan Jing
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Patent number: 8953157Abstract: A remote sensor element for spectrographic measurements employs a monolithic assembly of one or two fiber optics to two optical elements separated by a supporting structure to allow the flow of gases or particulates therebetween. In a preferred embodiment, the sensor element components are fused ceramic to resist high temperatures and failure from large temperature changes.Type: GrantFiled: February 1, 2012Date of Patent: February 10, 2015Assignee: Wisconsin Alumni Research FoundationInventor: Scott Sanders
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Patent number: 8952132Abstract: Methods and compositions involving polypeptides having an aglycosylated antibody Fc domain. In certain embodiments, polypeptides have an aglycosylated Fc domain that contains one or more substitutions compared to a native Fc domain. Additionally, some embodiments involve an Fc domain that is binds some Fc receptors but not others. For example, polypeptides are provided with an aglycosylated Fc domain that selectively binds Fc?RIIa, but that is significantly reduced for binding to the highly homologous Fc?RIIb receptors. Furthermore, methods and compositions are provided for promoting antibody-dependent cell-mediated toxicity (ADCC) using a polypeptide having a modified aglycosylated Fc domain and a second non-Fc binding domain, which can be an antigen binding region of an antibody or a non-antigen binding region. Some embodiments concern antibodies with such polypeptides, which may have the same or different non-Fc binding domain.Type: GrantFiled: February 6, 2012Date of Patent: February 10, 2015Assignee: Research Development FoundationInventors: George Georgiou, Sang Taek Jung, William Kelton, Tae Hyun Kang
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Patent number: 8951563Abstract: Disclosed are compositions-of-matter comprising polymer-mediated cochleates, which are formed from a calcium-free mixture of a wide variety of phospholipids that are atypical for forming cochleates. Further disclosed are compositions-of-matter comprising these cochleates which co-encapsulate another bioactive agent. The polymer mediating the formation of these cochleates exhibits a plurality of positively charged amino acid residues and omega-amino-fatty acid moieties, and may further exhibit antimicrobial, anticancerous and drug-potentiating activity. Further disclosed are pharmaceutical compositions and methods using the compositions-of-matter disclosed herein, and processes of preparing same.Type: GrantFiled: August 5, 2010Date of Patent: February 10, 2015Assignee: Technion Research & Development Foundation LimitedInventors: Amram Mor, Richard M. Epand, Raquel F. Epand, Brigitte Papahadjopoulos-Sternberg
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Patent number: 8953725Abstract: Provided is a MIMO repeater system including a plurality of repeaters. Each of the repeaters includes: an Rx antenna; a receiver configured to convert a signal received through the Rx antenna into a digital signal; an interference cancellation unit configured to cancel interference from an output signal of the receiver; a transmitter configured to convert an output signal of the interference cancellation unit into an analog signal; and a Tx antenna configured to transmit an output signal of the transmitter, and the interference cancellation to unit provided in each of the repeaters receives the output signal of the receiver as an input signal, receives reference signals provided from the plurality of repeaters as a reference signal vector, outputs a prediction signal according to a current filter coefficient vector generated in response to the input signal and the reference signal vector, and cancels the prediction signal from the input signal.Type: GrantFiled: October 30, 2013Date of Patent: February 10, 2015Assignee: SNU R&DB FoundationInventor: Jung Woo Lee
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Patent number: 8952140Abstract: A compound having a structure expressed by the following General Formula (1) or a salt thereof where “R” denotes a hydrogen atom or an alkyl group.Type: GrantFiled: February 23, 2012Date of Patent: February 10, 2015Assignee: Microbial Chemistry Research FoundationInventor: Shigehiro Tohyama
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Patent number: 8953411Abstract: Provided are an apparatus and method for imaging a subsurface using frequency-domain reverse-time migration in elastic medium. The subsurface imaging method represents a frequency-domain imaging condition as convolution of measured data and a partial derivative wavefield. That is, the subsurface imaging method applies a back-propagation algorithm to represent an imaging condition as convolution of a virtual source and a back-propagated wavefield. Then, the subsurface imaging method divides a virtual source vector and the back-propagated wavefield represented by a displacement vector into P- and S-wave potentials through Helmholtz decomposition, thereby providing a new imaging condition.Type: GrantFiled: June 15, 2011Date of Patent: February 10, 2015Assignee: SNU R&DB FoundationInventor: Changsoo Shin
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Patent number: 8952706Abstract: A conduit survey apparatus having a carriage capable of movement axially down a conduit. The carrier includes a radio frequency (RF) signal generator and an RF signal detector positioned on the carriage along with a controller controlling the signal generator and signal detector. The carrier further includes a waveguide with an open throat transmitting signals from the signal generator and directing received signals to the signal detector. Finally, the carrier includes a waveguide positioner mounted on the carrier and adapted to selectively engage an interior wall of the conduit, wherein the waveguide guide is connected to the positioner such that the open throat of the waveguide is within about 1 inch of the interior wall when the positioner engages the interior wall.Type: GrantFiled: March 29, 2012Date of Patent: February 10, 2015Assignee: Louisiana Tech University Research FoundationInventors: Erez Allouche, Arun Prakash Jaganathan
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Patent number: 8953707Abstract: A code word selection method performed by a User Equipment (UE) in a wireless communication system is provided. The method includes generating a rotation matrix using previously selected codeword; generating a new differential code book using the rotation matrix and a differential code book; selecting a code word from the new differential code book; and performing data transmission using the selected code word.Type: GrantFiled: October 19, 2012Date of Patent: February 10, 2015Assignees: Samsung Electronics Co., Ltd, Purdue Research FoundationInventors: Sangmin Ro, Junil Choi, David J. Love, Juho Lee
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Patent number: 8954321Abstract: A Unified Speech and Audio Codec (USAC) that may process a window sequence based on mode switching is provided. The USAC may perform encoding or decoding by overlapping between frames based on a folding point when mode switching occurs. The USAC may process different window sequences for each situation to perform encoding or decoding, and thereby may improve a coding efficiency.Type: GrantFiled: November 26, 2009Date of Patent: February 10, 2015Assignees: Electronics and Telecommunications Research Institute, Kwangwoon University Industry-Academic Collaboration FoundationInventors: Seungkwon Beack, Tae Jin Lee, Min Je Kim, Kyeongok Kang, Dae Young Jang, Jeongil Seo, Jin Woo Hong, Chieteuk Ahn, Ho Chong Park, Young-cheol Park
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Patent number: 8951462Abstract: Provided is a method of manufacturing porous ceramic bodies with gradient of porosity, in which a gradient that is continuous to a pore size and porosity is precisely controlled in a simple way. The method includes the steps of: obtaining molded bodies by pressurizing and molding a mixture of powder obtained by mixing ceramic powder and polymer powder at a weight ratio of 1:1 to 100:1; and obtaining sintered bodies with gradient of porosity by sintering the molded bodies while applying a gradient pressure to the molded bodies.Type: GrantFiled: June 19, 2012Date of Patent: February 10, 2015Assignee: SNU R&DB FoundationInventors: Kug Sun Hong, Ki Tae Nam, Hae Lin Jang, Kyoung Suk Jin, Jingming Xu, Tae-Youl Yang, Jimin Park, Hui-Yun Jeong
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Patent number: 8954087Abstract: Disclosed herein are an apparatus and method for providing communication services. The apparatus includes a location information acquisition unit, a radio station information acquisition unit, and an offloading unit. The location information acquisition unit acquires information about the current location of the user terminal by sending a location information request message to the user terminal. The radio station information acquisition unit requests information about a white space radio station from which the user terminal can receive the communication services by sending the information about the current location of the user terminal to a white space server, and acquires, from the white space server, information about an available white space radio station. The offloading unit sends the information about the available white space radio station to the user terminal, and also sends information about the user terminal to the available white space radio station.Type: GrantFiled: August 22, 2012Date of Patent: February 10, 2015Assignee: Foundation of Soongsil University-Industry CooperationInventors: Won-Cheol Lee, Hyung-Min Chang, Joo-Pyoung Choi, Han-Nah Choi
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Patent number: 8950362Abstract: An otter habitation section, an overland section, an inclined-surface section, a first spawning section, a second spawning section and a roost are all provided. Accordingly, otters and birds can sufficiently obtain preys, and fishes secure a spawning ground suitable for spawning characteristics. Therefore, the otters, the fishes and the birds can inhabit together. Further, since frames are made of wood for providing buoyant force or the frames are made of stainless steel for reinforcing strength and wood for providing buoyant force, a small amount of polyethylene foam is required. Accordingly, it is possible to obtain floating wetland equipment with a simple structure. Furthermore, the wooden frames itself provide a spawning ground of fishes.Type: GrantFiled: April 6, 2012Date of Patent: February 10, 2015Assignees: Kangwon National University University-Industry Cooperation Foundation, Korea Water Resources Corporation, Halla Engineering & Construction Corp.Inventors: Woo Myung Heo, Gil Son Hwang, Dong Oug Kim, Ho Joon Kim, Dong Seop Kim, Sun Hee Lee, Haeng Seop Song
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Patent number: 8950886Abstract: A solar-powered lighting module is provided, including a solar cell for generating electricity when exposed to light, a battery for storing charge from the generated electricity, and a light generating device powered by the stored charge. In an embodiment, the module further includes a controller that regulates the current transmitted between the components of the module. In a further embodiment, the module is incorporated into an interface to an environmentally controlled space and can be positioned to light an interior portion of the space. In another embodiment, the solar cell and light generating device are transparent to allow light to pass through the interface. In a further embodiment, tinted-color conjugated polymers incorporated into the module limit the spectrum of light that can pass through the interface. In yet another embodiment, a method of modifying an existing interface with such a module is provided.Type: GrantFiled: June 2, 2010Date of Patent: February 10, 2015Assignee: University of Florida Research Foundation, Inc.Inventors: Ying S. Meng, Karl R. Zawoy, Jiangeng Xue, Franky So, John R. Reynolds
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Patent number: 8951990Abstract: Described herein are methods for treating a dental disorder in a subject comprising administering to the subject an effective amount of a modified hyaluronan or a pharmaceutically acceptable salt or ester thereof, wherein said hyaluronan or its pharmaceutically acceptable salt or ester comprises at least one sulfate group and the primary C-6 hydroxyl proton of at least one N-acetyl-glucosamine residue is substituted with a C1-C10 unsubstituted alkyl group or fluoroalkyl group.Type: GrantFiled: January 7, 2013Date of Patent: February 10, 2015Assignee: University of Utah Research FoundationInventors: Glenn Prestwich, Jianxing Zhang, Sr., Thomas P. Kennedy, Narayanam Rao
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Patent number: 8953239Abstract: A method of designing a nanophotonic scattering structure can include establishing an initial design having an array of discrete pixels variable between at least two pixel height levels. A performance metric for the structure can be a function of the heights of the pixels. The height of a pixel can be varied, and then the performance metric can be calculated. The steps of varying the pixel height and calculating the performance metric can be repeated to increase the performance metric. The above steps can be repeated for each pixel within the array and then the method can be iterated until the performance metric reaches an optimized value. Nanophotonic scattering structures can be produced from designs obtained through this process.Type: GrantFiled: September 5, 2013Date of Patent: February 10, 2015Assignee: University of Utah Research FoundationInventors: Rajesh Menon, Peng Wang
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Patent number: 8952693Abstract: A method for calculating a mechanical property of a material using a magnetic resonance imaging (“MRI”) system is provided. The method is particularly robust to image data having low signal-to-noise ratio (“SNR”). An MRI system is used to acquire magnetic resonance elastography (“MRE”) data from a subject containing the material. Exemplary materials include lung tissue. Images are reconstructed from the MRE data and used to produce a wave image from which a spatial frequency spectrum is produced. A principal frequency of the spatial frequency spectrum is produced and used to calculate a mechanical property of the material. For example, shear stiffness may be calculated.Type: GrantFiled: April 23, 2012Date of Patent: February 10, 2015Assignee: Mayo Foundation for Medical Education and ResearchInventors: David S Lake, Kiaran P McGee, Armando Manduca, Yogesh K Mariappan, Richard L Ehman
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Patent number: 8952319Abstract: Downhole deployable tools for measuring tracer concentrations are disclosed. According to one embodiment, an apparatus comprises a support cable configured to allow the apparatus to be lowered into and raised from a wellbore. A housing is attached to the support cable. The housing includes a detector window on the exterior of the housing. A detector system within the housing includes a detector that measures tracer concentrations. The detector is operably connected to the detector window to direct energy or particles from the detector window to the detector.Type: GrantFiled: March 4, 2011Date of Patent: February 10, 2015Assignee: University of Utah Research FoundationInventor: Peter E. Rose