Abstract: The invention provides a method of reducing or preventing mitochondrial permeability transitioning. The method comprises administering an effective amount of an aromatic-cationic peptide having at least one net positive charge; a minimum of four amino acids; a maximum of about twenty amino acids; a relationship between the minimum number of net positive charges (pm) and the total number of amino acid residues (r) wherein 3pm is the largest number that is less than or equal to r+1; and a relationship between the minimum number of aromatic groups (a) and the total number of net positive charges (pt) wherein 2 a is the largest number that is less than or equal to pt+1, except that when a is 1, pt may also be 1.

Abstract: A method of manufacturing a light emitting diode, includes a process of forming an n-type nitride semiconductor layer, a light emitting layer, and a p-type nitride semiconductor layer on a temporary substrate, a process of forming a p-type electrode on the p-type nitride semiconductor layer, a process of forming a conductive substrate on the p-type electrode, a process of removing the temporary substrate to expose the n-type nitride semiconductor layer, a process of forming a nanoimprint resist layer on the n-type nitride semiconductor layer, a process of pressing the nanoimprint mold on the nanoimprint resist layer to transfer the nano-pattern onto the nanoimprint resist layer, and a process of separating the nanoimprint mold from the nanoimprint resist layer having the nano-pattern and etching a portion of the nanoimprint resist layer having the nano-pattern to form an n-type electrode.

Abstract: Devices and methods are provided for combining the handle of a surgical instrument with a force feedback generator, able to create resistance to motion similar to that encountered in a real operating environment. The working end of the surgical instrument is recreated in a virtual environment and manipulated by the modified handle through the force feedback generator. Actions of the instrument handle modify a model and display of the virtual environment and transmit a haptic response back to the handle. The devices and methods provide a means for repeatedly performing maneuvers that accurately simulate the actual instrument, but in the virtual environment. The virtual environment is modeled to accurately simulate the use of the instrument including manipulation of and collisions with other virtual objects, such as surgical thread or internal tissues. Training and assessment tools are also provided that coach or assess a user's proficiency with the instrument.

Abstract: Systems and methods for depositing complex thin-film alloys on substrates are provided. In particular, systems and methods for the deposition of thin-film Cd1-xMxTe ternary alloys on substrates using a stacked-source sublimation system are provided, where M is a metal such as Mg, Zn, Mn, and Cu.

Abstract: An inner mold body includes a first pair of side walls opposite one another, each of the first pair of side walls having a pair of engagement members attached thereto, a second pair of side walls opposite one another; wherein each of the second pair of side walls is adjacent to each of the first pair of side walls, and a separation mechanism in contact with each of the second pair of side walls.

Abstract: A system for removing plant material from harvested crops includes a pinch roller conveyor including pairs of rotatable pinch rollers whose longitudinal axes are aligned with a length of the conveyor, the pinch rollers forming nips in which plant material can be caught and pulled down through the conveyor as the pinch rollers rotate, wherein first ends of the pinch rollers are laterally displaceable so that the pinch rollers can laterally separate from each other to facilitate passage of plant material.

Abstract: The present invention relates to devices and systems that alter intracranial compliance, cerebral blood flow and/or intracranial pressure pulsatility/waveform by oscillating the contraction and expansion of a compressible composition within the cranial or spinal cavities such that they increase intracranial capacity. The contraction and expansion of the compressible composition in the oscillating compliance devices can be due to an individual's intracranial pressure, the result of the expansion and compression of a reservoir which is mediated by the contractility of the heart or driven by a pump gaited to a biorhythm. The invention also relates to methods for protecting an individual's brain from abnormal arterial pulsations and for altering an individual's cerebral blood flow using the devices and systems of the invention.

Abstract: The present disclosure describes the isolation of extremophilic microorganisms from the Lakes of Schirmacher Oasis located in the East Antarctic Dronning Maud Land. The isolated organisms were characterized and certain pigments produced by these microorganisms were isolated. The present disclosure teaches that the isolated pigments exhibit anticancer and antimicrobial properties and can be used as new therapies for the treatment and prevention of cancer and microbially-mediated diseases.

Abstract: Various embodiments are directed to generating video data using temporally offset image data samples having disparate exposure times. Synthetic samples are generated for each of the pixels at a particular time period by computing, for each synthetic sample, a combined intensity of the captured samples that fall within the time period. Synthetic samples from adjacent pixels are grouped and image data in different groups is compared to identify matching groups. Video frames are constructed by combining image data from the captured samples based upon the matched images.

Abstract: Reliable, fast and inexpensive breath gas detector systems for medical diagnostics, including personal, handheld monitoring devices for a variety of diseases and conditions, including, for example, asthma, diabetes, blood cholesterol, and lung cancer. A sensor device (100) for detecting gases includes a sensing element (109) having an electrical resistance that changes in the presence of a target gas; a readout circuit, electrically coupled to the sensing element due to the presence of the target gas and converts the measurement to a digital signal; and a feedback loop (203) from a digital unit (205) to the readout circuit to compensate for variations in a baseline resistance of the sensing element.

Abstract: Methods are provided for producing biodegradable polyhydroxyalkanoates (PHAs) with desired geometry, molecular mass, mechanical and/or physical-chemical properties from glycerol, an inexpensive carbon source and byproduct of the biodiesel industry. Microorganisms capable of converting carbon to PHA can be used to convert biodiesel-glycerol to poly-3-hydroxybutyrate (PHB) or other monomer or copolymer PHAs via fermentation. The microorganisms are cultured in a medium comprising glycerol as a primary carbon source and one or more low molecular mass organic acids as a secondary carbon source. Biomass can be harvested from the culture medium and crude PHA extracted and purified, thereby recovering purified PHA with the desired property. After PHA isolation, a nucleating agent can be added to improve certain physical-chemical properties of the PHA, e.g., crystallization temperature, to enhance performance of the PHA during injection molding.

Abstract: A magnetic resonance imaging (“MRI”) system and method for producing an image of a subject with the MRI system in which signal contributions of water and fat are separated are provided. A plurality of in-phase echoes formed at a plurality of different echo times are sampled to acquire k-space data. The in-phase echoes include signal contributions from water and fat that are in-phase with each other. The signal contributions from water and fat are then separated by fitting only those echo signals that are in-phase echo signals to a signal model that models a fat spectrum as including multiple resonance peaks. From these signal contributions, an image of the subject depicting a desired amount of signal contribution from water and a desired amount of signal contribution is produced.

Abstract: Disclosed is a device for controlling a mouse pointer, providing a display unit; an image photographing unit for photographing images of a first object and a second object; and a controller for setting a point between the first object and the second object detected from the photographed images as a position of a mouse pointer on the display unit, and when a distance between the first object and the second object is less than a predetermined distance, determining that a user selection instruction for the point has been input. The device detects movement of fingers using differential images according to the movement of the fingers, so that even when a continuously changing surrounding lighting or a user face having the similar color with the finger is included in a background, it is possible to accurately identify the movement of the fingers.

Abstract: A cover is provided that is adapted to wrap around at least a portion of a child container such as a crib or play yard. The cover includes at least one fabric sheet having a surface area sufficient to cover substantially all of a top face of a mattress in the child container. The sheet includes at least one mattress fastener such as a sleeve or band that is operative to mount the sheet to the mattress. The cover also includes at least one panel connected to the sheet which wraps inner faces of the walls of the child container, which extends over the upper edges of the walls, and which extends over adjacent portions of the outer faces of the walls. The at least one panel includes at least one fastener component that is usable to fasten the cover adjacent the outer faces is of the child container.

Abstract: The disclosure describes alterations in ERG gene expression. ERG isoforms and promoter sequence of the ERG gene that are involved in, or associated with, prostate cancer are provided. The disclosure further provides therapeutic compositions and methods of detecting, diagnosing, prognosing, and treating prostate cancer, including biomarkers for detecting the expression of two or more of the following genes: PSA/KLK3, PMEPA1, NKX3.1, ODC1, AMD1, and ERG.

Abstract: A solar-energy module is disclosed. The module includes a first electrode configured to receive incident visible light with a different refractive index than the medium through which light travels prior to becoming incident on the first electrode, the first electrode having a first metasurface arrangement formed through the first electrode, and configured to selectively i) match the optical impedances of the first electrode and the medium, and ii) cause light to be refracted substantially away from normal refraction angle, a photon-absorbing material coupled to the first electrode on a first surface of the photon-absorbing material and configured to receive refracted light through the first electrode and adapted to produce an electrical current in response to the refracted light, length of the photon absorbing material substantially larger than thickness of the photon-absorbing material, and a second electrode coupled to the photon-absorbing material on a second surface of the photon-absorbing material.

Abstract: The present invention relates to a method for selective cell attachment/detachment, cell patternization and cell harvesting by means of near infrared rays. More particularly, conducting polymers or metal oxides having exothermic characteristics upon irradiation of near infrared light is used as a cell culture scaffold, thus selectively attaching/detaching cells without an enzyme treatment. The scaffold has an effect of promoting proliferation or differentiation of stem cells, and therefore, can be used as a stem cell culture scaffold. The scaffold enables cell attachment/detachment without temporal or spatial restrictions, thus enabling cell patternization.

Abstract: A precision densitometer for radiosensitive films and the like provides point-to-point scanning in which a laser source and collimated receiver are moved in tandem over the area of the film. The film may be supported only at its edges to remove scattering and interference caused by a glass support bed. Highly repeatable 25 ?m resolution density measurements may be obtained.

Abstract: A terminal apparatus included in a contents centric network and a communication method thereof are provided, the communication method including receiving an interest packet regarding a specific content from an external terminal apparatus, adjusting a window size of the interest packet based on at least one of a requesting frequency of the specific content corresponding to the interest packet and a communication status, and after adjusting the window size, transmitting the interest packet to surrounding terminal apparatuses.

Abstract: A tight confinement nanocrystal comprises a homogeneous center region having a first composition and a smoothly varying region having a second composition wherein a confining potential barrier monotonically increases and then monotonically decreases as the smoothly varying region extends from the surface of the homogeneous center region to an outer surface of the nanocrystal. A method of producing the nanocrystal comprises forming a first solution by combining a solvent and at most two nanocrystal precursors; heating the first solution to a nucleation temperature; adding to the first solution, a second solution having a solvent, at least one additional and different precursor to form the homogeneous center region and at most an initial portion of the smoothly varying region; and lowering the solution temperature to a growth temperature to complete growth of the smoothly varying region.