Patents Assigned to Foundation
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Patent number: 9976940Abstract: The present invention relates to a composition for DNA staining, which can be safely used for researchers, can prevent DNA photocleavage, and can be applied to various fields. According to the present invention, when DNA is stained by using a fluorescent protein and a particular peptide bound to DNA, such a fluorescent protein-peptide is safe to researchers, suppresses DNA photocleavage, and allows reversible staining, thereby enabling efficient DNA staining. Therefore, the composition for DNA staining of the present invention can be variously used in DNA-related research.Type: GrantFiled: September 9, 2015Date of Patent: May 22, 2018Assignee: INDUSTRY-UNIVERSITY COOPERATION FOUNDATION SOGANG UNIVERSITYInventors: Kyu Bong Jo, Seong Hyun Lee, David C. Schwartz
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Patent number: 9975117Abstract: Provided is an apparatus and method for controlling a droplet. The apparatus for controlling the droplet does not contaminate/damage a sample, has a high degree of freedom in droplet control, and is capable of being repeatedly used for a long time. An apparatus (100) for controlling a droplet according to an embodiment includes a flexible substrate (120) having a hydrophobic or oleophobic surface, a dimple formation unit (140), which locally deforms a bottom surface of the flexible substrate (120) to form a dimple, and a driving unit (160), which moves the dimple formation unit (140) at a lower side of the flexible substrate.Type: GrantFiled: May 5, 2016Date of Patent: May 22, 2018Assignee: Industry-Academic Cooperation Foundation, Yonsei UniversityInventors: Taeyoon Lee, Jonghyun Ahn, Jungmok Seo, Seoung Ki Lee
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Patent number: 9979160Abstract: An optical circulator is a device that routes optical pulses from port to port in a predetermined manner, e.g. in a 3-port optical circulator, optical pulses entering port 1 are routed out of port 2, while optical pulses entering port 2 exit out of port 3 and optical pulses fed into port 3 exit out of port 3. Currently such an optical circulator is made of discrete components such as magnetooptic garnets, rare-earth magnets and optical polarizers that are packaged together with fiber optic elements. Disclosed herein is a different kind of optical circulator that is monolithically integrated on a single semiconductor substrate and that is applicable for the routing of optical pulses. The embodied invention will enable photonic integrated circuits to incorporate on-chip optical circulator functionality thereby allowing much more complex optical designs to be implemented monolithically.Type: GrantFiled: June 20, 2017Date of Patent: May 22, 2018Assignee: UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC.Inventors: Demetrios Christodoulides, Patrick L. LiKamWa, Parinaz Aleahmad, Ramy El-Ganainy
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Patent number: 9977109Abstract: Provided is a magnetic resonance imaging (MRI) apparatus.Type: GrantFiled: November 11, 2014Date of Patent: May 22, 2018Assignees: SAMSUNG ELECTRONICS CO., LTD., INDUSTRY-ACADEMIC COOPERATION FOUNDATION, YONSEI UNIVERSITYInventors: Young-woon Lee, Jin-seong Jang, Do-sik Hwang, Tae-joon Eo, Hae-kyung Jung, Dong-hyun Kim, Min-oh Kim, Na-rae Choi, Dong-yeob Han
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Patent number: 9979649Abstract: An associative memory that can be integrated with standard computer memory flexibly reduces its parallelism to match the memory bus speed thereby providing substantial increases in memory density possible by a multiplexing of sense amplifiers that otherwise dominate the memory structure. Apparent parallel operation is provided by an accumulator that reassembles the multiplex data. Higher memory density makes dual use of the associative memory as a content addressable memory and random-access memory possible.Type: GrantFiled: December 4, 2015Date of Patent: May 22, 2018Assignee: Wisconsin Alumin Research FoundationInventor: Jing Li
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Patent number: 9977112Abstract: Object localization with an radio-frequency identification (RFID) infrastructure is described. A plurality of transmission power levels established by an RFID reader can be searched to determine a measurement power level corresponding to a target. A region that includes the target can then be determined using information about a physical relationship between the RFID reader and a reference location via correlating the measurement power level to a reference power level corresponding to the reference location.Type: GrantFiled: September 23, 2011Date of Patent: May 22, 2018Assignee: University of Virginia Patent FoundationInventors: Kirti Chawla, Gabriel Robins
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Patent number: 9975933Abstract: A tumor tissue-penetrating peptide specifically binding to neuropilin, or a fusion protein, a small molecule drug, a nanoparticle, or a liposome having the peptide fused therein is provided, as well as a method for preparing the same and a pharmaceutical composition comprising the same for treating, diagnosing, or preventing cancer or angiogenesis-related diseases. The tumor tissue-penetrating peptide is fused to the C-terminus of an anticancer antibody heavy-chain constant region (Fc) and the fused antibody specifically binds to neuropilin, and specifically accumulates in tumor tissue, widens intercellular gaps between tumor vascular endothelial cells, promotes extravasation, increases infiltration within tumor tissue, and shows a remarkably increased in vivo tumor-suppressing activity.Type: GrantFiled: May 22, 2014Date of Patent: May 22, 2018Assignee: AJOU UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATIONInventors: Yong Sung Kim, Tae Hwan Shin, Yae Jin Kim, Eun Sil Sung
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Patent number: 9976939Abstract: A laser ablation tomography system includes a specimen stage for supporting a specimen. A specimen axis is defined such that a specimen disposed generally on the axis may be imaged. A laser system is operable to produce a laser sheet in a plane intersecting the specimen axis and generally perpendicular thereto. An imaging system is operable to image the area where the laser sheet intersects the specimen axis.Type: GrantFiled: July 29, 2016Date of Patent: May 22, 2018Assignee: The Penn State Research FoundationInventors: Benjamin Hall, Jonathan Lynch, Edward W. Reutzel, Galen Lynch
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Patent number: 9976974Abstract: Osmolarity-responsive hydrogel sensors, particularly biosensors, containing quaternary ammonium functionality, which are useful for, inter alia, continuous osmolarity monitoring with no pH interference, are disclosed. Methods of using the osmolarity-responsive hydrogels are also disclosed.Type: GrantFiled: January 26, 2016Date of Patent: May 22, 2018Assignee: University of Utah Research FoundationInventors: Tram Nguyen, Jules John Magda, Seung-Hei Cho, Prashant Tathireddy
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Patent number: 9976118Abstract: A method for inducing tailored pluripotent stem cells by reprogramming differentiated cells of an adult by using an extract of plant stem cells and plant dedifferentiated stem cells (callus); pluripotent stem cells produced by means of the method; and a cell therapy agent comprising the pluripotent stem cells are disclosed. It is possible to overcome ethical problems since eggs are not used in the making of pluripotent stem cells having abilities like embryonic stem cells. It is possible to produce pluripotent stem cells of ensured safety because a plant stem cell extract which above all has been verified to be harmless to the body is used. It is possible to develop an immunocompatible cell therapy agent tailored to different individuals.Type: GrantFiled: January 28, 2014Date of Patent: May 22, 2018Assignee: SNU R&DB FOUNDATIONInventors: Yoo-Wook Kwon, Young-Bae Park, Hyo-Soo Kim, Jae-Seung Paek
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Patent number: 9974957Abstract: Sensory information can be delivered to a subject mammal, for example, for restoring a sense of cutaneous touch and limb motion to the subject mammal. A biomimetic electrical signal is generated based on (a) a stimulation reference signal applied to a somatosensory region of a nervous system of a reference mammal, (b) a stimulated-response signal acquired from a sensory cortex of the reference mammal in response to application of the stimulation reference signal to the thalamic nucleus, and (c) a natural-response signal acquired from the sensory cortex in response to peripheral touch stimuli and/or peripheral nerve stimulation of the reference mammal. The biomimetic electrical signal is applied to a somatosensory region of a nervous system of the subject mammal to induce an activation response, in a sensory cortex of the subject mammal.Type: GrantFiled: April 14, 2015Date of Patent: May 22, 2018Assignee: THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORKInventors: John S. Choi, Joseph T. Francis
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Patent number: 9977806Abstract: A skyline query is a query on a set of tuples which are not dominated by other tuples. The skyline query system includes a sky quad tree generator that generates a quad tree from data, and marks a leaf node, which cannot include a local skyline, as being dominated; a local skyline calculator that computes a local skyline of each leaf node, which is not marked as being dominated, in the sky quad tree; and a global skyline calculator that computes a global skyline by using the local skyline. A quad tree is a tree where each internal node has exactly four children. The skyline query is a query for calculating a skyline, a dynamic skyline, or a reverse skyline from the data, where a dynamic skyline includes dynamic attributes and a reverse skyline identifies queries corresponding to certain skyline results.Type: GrantFiled: October 31, 2014Date of Patent: May 22, 2018Assignees: SNU R&DB Foundation, Korea University of Technology and Education Industry-University Cooperation FoundationInventors: Kyuseok Shim, Yoonjae Park, Jun-Ki Min
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Patent number: 9977652Abstract: Disclosed embodiments include systems, methods, and computer-readable media for generating pseudo-random numbers. Disclosed embodiments may receive, by the at least one processor, range data indicating a range of numbers. Disclosed embodiments may generate, based on the range data and by the at least one processor, a digitized finite state machine configured to produce pseudo-random output within the range of numbers. Further, disclosed embodiments may provide, by the at least one processor to a specialized pattern-matching device, programmable instructions to implement the digitized finite state machine on the specialized pattern-matching device. Disclosed embodiments may transmit, by the at least one processor to the specialized pattern-matching device, a pseudo-random bit stream for processing by the digitized finite state machine. Disclosed embodiments may receive, by the at least one processor from the specialized pattern-matching device, pseudo-random output from the digitized finite state machine.Type: GrantFiled: April 6, 2016Date of Patent: May 22, 2018Assignee: University of Virginia Patent FoundationInventors: John Pierson Wadden, Nathan James Brunelle
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Patent number: 9978911Abstract: Provided is a GaN light-emitting diode (LED) device. The LED device may include a substrate, an n-type GaN layer on the substrate, an active layer on the n-type GaN layer, a p-type GaN layer on the active layer, a current spreading layer including a transparent conductive metal oxide material on the p-type GaN layer, a plurality of upper current injection electrodes provided on the current spreading layer to be spaced apart from each other, an upper electrode pattern extending to cover the upper current injection electrodes, and an upper electrode pad electrically connected to the upper electrode pattern. The upper electrode pattern may include first and second upper electrode patterns, which are sequentially stacked and are a silver or silver alloy thin layer and a transparent conductive metal oxide thin layer, respectively.Type: GrantFiled: May 30, 2017Date of Patent: May 22, 2018Assignee: Korea University Research and Business FoundationInventors: Tae Yeon Seong, Jee-Yun Lee, Dae-Hyun Kim, Ki Seok Kim
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Patent number: 9977294Abstract: Provided are a liquid crystal display device and a method for driving same. The liquid crystal display device comprises the liquid crystal display device in a PVA mode, an LVA mode, an FFS mode, and in an IPS mode. The liquid crystal display device comprises 1 to 50 wt % of an achiral smectic liquid crystal, and a remainder of a nematic liquid crystal. The liquid crystal device comprises 3 to 50 wt % of a smectic liquid crystal and a remainder of the nematic liquid crystal, wherein the smectic liquid crystal comprises a liquid crystal layer, comprising 70 to 97 wt % of an achiral smectic liquid crystal, and 3 to 30 et % of a chiral smectic liquid crystal.Type: GrantFiled: June 25, 2013Date of Patent: May 22, 2018Assignee: INDUSTRY-UNIVERSITY COOPERATION FOUNDATION HANYANG UNIVERSITYInventors: Jae-Hoon Kim, You-Jin Lee
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Patent number: 9980150Abstract: A node device using a TV white space (TVWS) includes a decision unit for comparing energy levels of a first sub-channel and at least one second sub-channel adjacent to the first sub-channel among a plurality of sub-channels with respect to a digital TV (DTV) channel including the plurality of sub-channels and deciding whether the DTV channel is an available channel, and a discovery unit for, if the DTV channel is decided as the available channel, discovering a beacon by scanning the first sub-channel in the DTV channel.Type: GrantFiled: February 19, 2016Date of Patent: May 22, 2018Assignee: AJOU UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATIONInventors: Jae Bum Kim, Ji Na Han, Young Bae Ko
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Patent number: 9976315Abstract: An elongate member, reinforcement system and associated methods is disclosed. The system can include an elongate member, a structure associated with an end of the elongate member, a support member coupled to the structure and laterally offset from the elongate member extending about an end portion of the elongate member, a support layer surrounding the end portion of the elongate member such that at least a portion of the support member is between the support layer and the elongate member, and a structural filler disposed between the support layer and the elongate member. A load tending to cause relative movement of the end portion of the elongate member and the structure can be transferred through the structural filler and the support member to provide support for the elongate member.Type: GrantFiled: August 8, 2014Date of Patent: May 22, 2018Assignee: University of Utah Research FoundationInventors: Chris P. Pantelides, Lawrence D. Reaveley
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Patent number: 9977023Abstract: The present invention relates to a composition comprising a probe for detecting six representative causative viruses of acute enteritis (norovirus genogroup I and genogroup II, rotavirus, hepatitis A virus, coxsackievirus, astrovirus, and adenovirus), and a DNA microarray, a kit, and a detection method comprising the composition. The present invention is effective due to high specificity and sensitivity to viruses. In addition, since the causative viruses can simply be detected at low cost compared to conventional detection methods, without expensive diagnosis devices or specialists, the present invention may be effectively used as a method for diagnosing viruses causing acute enteritis.Type: GrantFiled: November 26, 2015Date of Patent: May 22, 2018Assignee: Catholic University Industry Academic Cooperation FoundationInventors: Soon-young Paik, Yu-jeong Won
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Patent number: 9975557Abstract: A method of controlling an electric vehicle transmission includes: a torque-securing step of securing a predetermined spare torque to be generated by a motor in accordance with a current motor torque when a controller determines that there is a need for downshift from an upper gear step to a lower gear step; a slip-controlling step of generating a friction force through a servo clutch applying a friction force between an input shaft and a servo driving gear of a pair of servo gears; a shifting-to-neutral step of shifting to a neutral gear by disengaging a synchronizer for the upper gear step; a motor-synchronizing step of synchronizing a rotational speed of the motor with a desired speed of a lower gear step using the spare torque of the motor secured in the torque-securing step; a gear-engaging step of engaging a synchronizer for the lower gear step; and a clutch-disengaging step of finishing shifting by disengaging the servo clutch.Type: GrantFiled: May 2, 2016Date of Patent: May 22, 2018Assignees: HYUNDAI MOTOR COMPANY, RESEARCH & BUSINESS FOUNDATION SUNGKYUNKWAN UNIVERSITYInventors: Jong Yun Park, Kyung Ha Kim, Jae Young Choi, Yeon Ho Kim, Sung Wha Hong
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Patent number: 9978458Abstract: A data read operation method of a memory device includes applying a read voltage having a first preparation level and a first target level to a word line of a selected cell in the memory device to read a program state of the selected cell, applying a first read pass voltage having a second preparation level and a second target level to at least one word line of first non-selected cells not adjacent to the selected cell and in the same string as the selected cell, and applying a second read pass voltage having a third target level to a word line of at least one second non-selected cell adjacent to the selected cell.Type: GrantFiled: December 19, 2016Date of Patent: May 22, 2018Assignees: Samsung Electronics Co., Ltd., Industry-Academic Cooperation Foundation, Yonsei UniversityInventors: Yo-han Lee, Ji-suk Kim, Chang-yeon Yu, Jin-young Chun, Se-heon Baek, Jun-young Ko, Seong-ook Jung, Ji-su Kim