Abstract: The present invention relates to an enhancer which functions only in human brain and/or spinal cord motor neurons, where the enhancer comprises a nucleotide sequence of SEQ ID NO: 5, SEQ ID NO: 10, or SEQ ID NO: 16. The enhancer can be utilized as part of a nucleic acid construct which also has a nucleic acid encoding a marker protein or a therapeutic protein, a 3? control region, and, optionally, a basal promoter, where these components are positioned with respect to one another to permit expression of the marker protein or the therapeutic protein. The enhancer of the present invention is useful in a method of isolating an enriched or purified population of motor neurons from a mixed population of human brain and/or spinal cells. In addition, the enhancer of the present invention can be used in a method of therapeutically targeting motor neurons.

Abstract: The present invention is directed to small interfering RNA molecules (siRNA) targeted against nucleic acid sequence that encodes huntingtin or ataxin-1, and methods of using these siRNA molecules.

Abstract: Deformation maps (e.g. deformation vector fields) used for correcting image-type data used in the treatment of patients in radiotherapy may be processed to eliminate inverse inconsistency and transitivity type errors which produce different results depending on the order or path of the calculation of deformation. The correction permits registration of a treatment plan with the changing patient image and accumulation of dose to a common reference frame without transformation dependent artifacts.

Abstract: A robot hand with a connection part that undergoes stretching deformation according to object shape. The robot hand includes a variable connection device that provides a contact face that enables pressing and contacting a moving target and has a connection part in contact with the moving target enables stretching deformation; a connection length controller that interfaces with a drive part to stretch and deform the connection part so that the connection part undergoes conversion between a closed-loop state wherein it is continuous with the surface of the moving target or divided into a plurality of sections to be pressed and contacted, and an open-loop state wherein it detaches from the moving target; and a shape retention device that retains the shape of the variable connection device consistently in a closed-loop state wherein the variable connection device is pressed and contacted with the moving target at a set pressure.

Abstract: A method is provided for detecting a target molecule in a biological sample. One step of the method includes immobilizing the biological sample on a membrane. Next, the membrane-bound biological sample is contacted with at least one detection moiety. The membrane-bound biological sample is then separately mated with a substrate and the target molecule detected. At least one step of the method is performed under positive pressure or a vacuum.

Abstract: Disclosed is an apparatus and method for ray-tracing using a path preprocess. The method for ray-tracing including launching a ray from a transmitting point at angles with regular intervals, setting a first side of an object where the launched ray is projected as a reference patch, and searching predetermined preprocessed path data for a counterpart patch corresponding to a second side of another object, the second side being exposed to the projected ray reflected or diffracted from the set reference patch, and tracing a transmission path of the reflected or diffracted ray.

Abstract: A sunroof mounting device is provided, which includes guide rails of which the entire width is reduced by a pair of first and second guiders arranged up and down such that a moving-connecting portion connected to a sunroof is vertically combined in an open space from a side, such that the space opened by the sunroof is not covered by guide rails and improved open feel.

Abstract: Disclosed is a BSLM method of generating U independent alternative symbol sequences by changing a phase of symbol sequences by phase sequences and transmitting the alternative symbol sequences with a PAPR to lower the PARR of a transmission signal of a transmitter in an OFDM system. The transmitter uses m-sequences as the phase sequence and a receiver uses an ML decoder to distinguish the phase sequence. The BSLM method includes rotating phases in blocks according to the m-sequences used in the respective symbol sequences, selecting a signal sequence with a minimum PAPR among U alternative signal sequences generated by the m-sequences in the transmitter, and partitioning U alternative symbol sequences into U/2 blocks in the transmitter. Block partitioning and predetermined phase rotation are used to embed side information in an alternative signal sequence, and the BSLM scheme may be extended to a BPTS.

Abstract: The invention involves methods and products related to the micronization of hydrophobic drugs. A method of micronizing hydrophobic drugs using a set of solutions including an aqueous solution is provided. The invention also relates to products of micronized hydrophobic drugs and related methods of use.

Abstract: A method and apparatus for enhanced THz radiation coupling to molecules, includes the steps of depositing a test material near the discontinuity edges of a slotted member, and enhancing the THz radiation by transmitting THz radiation through the slots. The molecules of the test material are illuminated by the enhanced THz radiation that has been transmitted through the slots, thereby producing an increased coupling of EM radiation in the THz spectral range to said material. The molecules can be bio-molecules, explosive materials, or species of organisms. The slotted member can be a semiconductor film, a metallic film, in particular InSb, or layers thereof. THz detectors sense near field THz radiation that has been transmitted through said slots and the test material.

Abstract: Disclosed is a noise suppression device capable of better noise suppression by means of a simpler structure and with a lighter computational load. A noise suppression device (100) has a noise suppression processor (150) to estimate the required information only from the observed information, which is the required information corrupted by noise. A correlator (154) calculates the correlation of the estimation error when the state quantity, which contains the required information, of the system at time n+1 was estimated from the information until time n or time n+1 for the observed information at only time n.

Abstract: Systems and methods for microwave tomography are described. According to various embodiments, signal strength values or other similar quality indications may be analyzed as they are received with packet data over a wireless network. The analysis may be used to determine the presence of a physical object substantially between communicating nodes in the wireless network. An output may be generated based on analyzed data. Other embodiments are described and claimed.

Abstract: Impedance matching between the RF probe and the spectrometer is a standard requirement for NMR probes. Both lumped element and branched transmission line methods are in wide use. Here we propose to use a segmented transmission line structure. It relies upon reflections between transmission lines of different impedances that are serially connected to match the impedance of a coil or resonator to the characteristic impedance of the NMR spectrometer. In an embodiment, two quarter-wave length dielectric slugs are placed within a coaxial transmission line. Adjustment of the positions of the slugs allows the variable tuning and matching needed for NMR probes, eliminating the need for variable capacitors and inductors.

Abstract: A computer-implemented sepsis alerting method is disclosed. The method involves automatically extracting with a computer system, from records maintained for a patient under care in a healthcare facility, information from a electronic medical record, and obtaining with the computer system information about real-time status of the patient. The method also involves using the information from the electronic medical record and the information about the real-time status to determine whether the patient is likely to be suffering from dangerous probability of sepsis, using information from the electronic medical record to determine whether treatment for sepsis is already being provided to the patient, and electronically alerting a caregiver over a network if it is determined that a potentially dangerous level of sepsis exists and that treatment for sepsis is not already being provided.

Abstract: Caps can be used to cover and disinfect medical connectors. Some caps can create a seal with the medical connectors to prevent antiseptic from entering a fluid paths defined by a connector. Support members can aid in creating or maintaining the seal.

Abstract: A method of fabricating a liquid for an oxide thin film is provided, which includes mixing at least two kinds of dispersoids selected from the group consisting of a Zinc compound, an Indium compound, a Gallium compound, a Tin compound and a Thallium compound, with dispersion media corresponding to the selected dispersoids to form a dispersion system, and stirring and aging the dispersion system at a predetermined temperature for a predetermined time, wherein a molar ratio of the Zinc compound to each of the Indium compound, Gallium compound, Tin compound and Thallium compound is 1:0.1 to 1:2. According to the present invention, the liquid for the oxide thin film may be fabricated by a sol-gel method making it capable of being implemented in mass production in a simple and low-cost manner as opposed to the conventional vacuum deposition method.

Abstract: This invention relates to altered forms of members of the RNase A superfamily. An RNase A can be modified to be cytotoxic by altering its amino acid sequence so that it is not bound easily by the ribonuclease inhibitor while still retaining catalytic properties. While earlier work had identified some modifications to RNase A that would result in cytotoxicity, the use of the FADE algorithm for molecular interaction analysis has led to several other locations that were candidates for modification. Some of those modifications did result in RNase A variants with increase cytotoxicity.

Abstract: Semi-supervised learning plays an important role in machine learning and data mining. The semi-supervised learning problem is approached by developing semiparametric regularization, which attempts to discover the marginal distribution of the data to learn the parametric function through exploiting the geometric distribution of the data. This learned parametric function can then be incorporated into the supervised learning on the available labeled data as the prior knowledge. A semi-supervised learning approach is provided which incorporates the unlabeled data into the supervised learning by a parametric function learned from the whole data including the labeled and unlabeled data. The parametric function reflects the geometric structure of the marginal distribution of the data. Furthermore, the proposed approach which naturally extends to the out-of-sample data is an inductive learning method in nature.

Abstract: A system for directly and instantaneously controlling the exciter of a generator. A voltage error calculator calculates a voltage error of output voltage of the generator which is regulated by an instruction voltage and a time constant. A switching signal generator generates switching signals in response to the voltage error. An exciter controller controls the exciter in response to the switching signals. Thus, the system can induce the maximum response characteristic of a power converter only by setting the time constant of a controller without a complicated design for determining gains of the controller. Further, the system can considerably inhibit overshoot from occurring in a transient response state.

Abstract: The present invention provides for methods and materials for diagnosing and treating neuromyelitis optica (NMO).