Patents Assigned to Foundation
  • Fused multi-layer amorphous selenium sensor
    Patent number: 12041796
    Abstract: A sensor including a layer of amorphous selenium (a-Se) and at least one charge blocking layer is formed by depositing the charge blocking layer over a substrate prior to depositing the amorphous selenium, enabling the charge blocking layer to be formed at elevated temperatures. Such a process is not limited by the crystallization temperature of a-Se, resulting in the formation of an efficient charge blocking layer, which enables improved signal amplification of the resulting device. The sensor can be fabricated by forming first and second amorphous selenium layers over separate substrates, and then fusing the a-Se layers at a relatively low temperature.
    Type: Grant
    Filed: January 22, 2021
    Date of Patent: July 16, 2024
    Assignee: THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK
    Inventors: James Scheuermann, Wei Zhao
  • Artificial intelligence-based methods for early drug discovery and related training methods
    Patent number: 12040094
    Abstract: An example method for training a graph convolutional neural network (GCNN) configured for virtual screening of molecules for drug discovery is described herein. The method can include receiving a first data set including a plurality of molecules, and training the GCNN to initialize one or more parameters of the GCNN using the first data set. The method can also include receiving a second data set including a plurality of molecules and respective inhibition rates for a disease, and training the GCNN to refine the one or more parameters of the GCNN using the second data set. The molecules in the first and second data sets can be expressed in a computer-readable format. An example method for virtually screening molecules on Plasmodium falciparum (P. falciparum) is also described herein.
    Type: Grant
    Filed: September 4, 2020
    Date of Patent: July 16, 2024
    Assignee: University of Central Florida Research Foundation, Inc.
    Inventors: Jiann-Shiun Yuan, Debopam Chakrabarti, Milad Salem, Arash Keshavarzi Arshadi
  • Methods for inducing a covert misclassification
    Patent number: 12039461
    Abstract: A method for inducing a covert misclassification performed on a non-transitory computer readable medium, the method includes identifying a target position. The method further includes creating a spectral perturbation tensor. The spectral perturbation tensor is configured to shift a projection of an initial spectrum towards the target position. Additionally, the method includes combining the spectral perturbation tensor to the initial spectrum. Further, the method includes classifying the combination of the spectral perturbation tensor and the initial spectrum with an established classifier, thereby designing the spectral perturbation tensor such that the combination is misclassified.
    Type: Grant
    Filed: September 10, 2019
    Date of Patent: July 16, 2024
    Assignee: Purdue Research Foundation
    Inventors: Garth Jason Simpson, James Ulcickas, Casey Smith, Alex Sherman
  • Particle-mediated delivery of biologics
    Patent number: 12036232
    Abstract: A composition for delivering a biologic to a subject generally includes a particulate substrate and an mRNA encapsulated by the particulate substrate. In some cases, the mRNA may be indirectly attached to the particulate substrate. The mRNA encodes at least one therapeutic polypeptide. The composition may be delivered to a tissue of a subject to provide a therapeutic benefit to the tissue.
    Type: Grant
    Filed: January 3, 2022
    Date of Patent: July 16, 2024
    Assignee: MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH
    Inventors: Atta Behfar, Andre Terzic
  • Image encoding/decoding method and apparatus, and recording medium for storing bitstream
    Patent number: 12041242
    Abstract: Disclosed herein is a method of decoding an image. The method includes determining a prediction mode of a current block as a merge mode with motion vector difference (MMVD), deriving a merge candidate list of the current block, deriving a motion vector predictor of the current block using the merge candidate list, deriving a motion vector difference of the current block, and deriving a motion vector of the current block using the motion vector predictor and the motion vector difference. Only some of candidates in the merge candidate list are used to derive the motion vector predictor.
    Type: Grant
    Filed: April 19, 2023
    Date of Patent: July 16, 2024
    Assignees: ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE, HANBAT NATIONAL UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION
    Inventors: Ha Hyun Lee, Jung Won Kang, Sung Chang Lim, Jin Ho Lee, Hui Yong Kim, Hae Chul Choi, Dae Hyeok Gwon, Jae Ryun Choi
  • Hybrid fluid film bearing
    Patent number: 12038047
    Abstract: Provided is a hybrid fluid film bearing. The hybrid fluid film bearing comprises: a bearing housing installed on an outer diameter surface of a rotary shaft in the form of being coupled via a ring; a sleeve ring installed between the rotary shaft and the bearing housing, having gaps respectively with the rotary shaft and the bearing housing, and having a side in the circumferential direction opened in the radial direction; and a fixing pin connected between the bearing housing and the sleeve ring, and supported by the bearing housing so as to restrict rotation of the sleeve ring when the rotary shaft rotates. Also, the hybrid fluid film bearing may further comprise a compliant spring damper which is provided in the gap between the bearing housing and the sleeve ring and is provided as one or more bump foils.
    Type: Grant
    Filed: May 17, 2022
    Date of Patent: July 16, 2024
    Assignee: INDUSTRY-UNIVERSITY COOPERATION FOUNDATION HANYANG UNIVERSITY ERICA CAMPUS
    Inventor: Keun Ryu
  • Heart valve therapeutic device
    Patent number: 12036121
    Abstract: A heart valve therapeutic device (1) comprises a coaptation assist valve (20) comprising a conduit (2) with an outer surface (3) for coaption with the native leaflets, and a prosthetic flow valve (5) mounted within the conduit (2) to allow one-way flow through the conduit (2). Support for the coaptation assist valve (20) is provided by a support (10) for positioning the conduit (2) across the native leaflets, and connectors (15) attaching the conduit (2) to the support (10).
    Type: Grant
    Filed: December 21, 2021
    Date of Patent: July 16, 2024
    Assignee: The Provost, Fellows, Foundation Scholars, and the Other Members Of Board, Of The College of the Holy and Undivided Trinity of Queen Elizabeth Near Dublin (TCD)
    Inventors: Paul Heneghan, Bruce Murphy, Lucy O'Keeffe, Martin Quinn, Conor Quinn
  • Method of synthesizing synchronized piezoelectric and luminescent material with piezoelectric ligands and light-emitting particles
    Patent number: 12037528
    Abstract: There is provided a method of preparing a synchronized piezoelectric and luminescence material. The method includes mixing a solution (a) including light-emitting particles or precursors thereof and a solution (b) including ligands having a piezoelectric property in a polar solvent; and optionally, mixing a solution (c) including ligands having a piezoelectric property in an antisolvent together with the solution (a) and the solution (b), if necessary.
    Type: Grant
    Filed: May 16, 2023
    Date of Patent: July 16, 2024
    Assignee: UIF (UNIVERSITY INDUSTRY FOUNDATION), YONSEI UNIVERSITY
    Inventors: Cheolmin Park, Seokyeong Lee, Joona Bang, Jaewan Ko, Taewoo Lee, Sungjin Kim
  • DNA-peptide composite comprising high-density functional group, DNA-peptide-nanomaterial composite and preparation method therefor, and DNA-metal nanowire and manufacturing method therefor
    Patent number: 12037580
    Abstract: The present invention relates to a DNA-peptide complex with a high-density functional group, a DNA-peptide-nanomaterial complex and a method for production of the same, a DNA-metal nanowire, and a method for production of the same. The DNA-peptide complex with a high-density functional group may include a DNA molecule; and a peptide containing an amino acid sequence capable of binding to the DNA molecule, wherein the peptide contains at least one functional group at a terminal thereof, wherein the peptide binds to the DNA molecule via at least one of electrostatic interaction, intercalation, and groove binding.
    Type: Grant
    Filed: October 31, 2017
    Date of Patent: July 16, 2024
    Assignees: Research & Business Foundation Sungkyunkwan University, Sogang University Research Foundation
    Inventors: Jung Heon Lee, Kyu Bong Jo, Kyung Il Kim, Seong Hyun Lee, Su Ji Kim, Xuelin Jin
  • Method, system and application for 3D molecular diffusion tensor measurement and structural imaging
    Patent number: 12038382
    Abstract: Herein are described data acquisition systems and methods applying such systems to determine three-dimensional (3D) diffusion tensors, and simultaneously, to perform 3D structure imaging. Example data acquisition systems can include computing systems in communication with modified light sheet microscopes that are configured for high-speed volumetric imaging to record 3D diffusion processes and high-resolution 3D structural imaging.
    Type: Grant
    Filed: July 16, 2021
    Date of Patent: July 16, 2024
    Assignee: CLEMSON UNIVERSITY RESEARCH FOUNDATION
    Inventors: Hai Yao, Tong Ye, Peng Chen, Xun Chen
  • Vehicle with non-physically coupled sections
    Patent number: 12037042
    Abstract: Systems and methods for a virtually coupled modular transportation system. A first module and a second module, in each for transporting a payload, comprise non-physically coupled vehicle sections. In an embodiment, a controller determines a target orientation between modules. In another embodiment, at least one position detection device determines an actual orientation between modules. A motor in at least one module may receive signals from the controller to position the modules in the target orientation. A plurality of wheels on each module may receive an independent amount of torque to position the modules. In another embodiment, at least one module comprises a rechargeable electric motor.
    Type: Grant
    Filed: August 16, 2017
    Date of Patent: July 16, 2024
    Assignee: Kennesaw State University Research and Service Foundation, Inc.
    Inventors: Billy M. Diong, Ying Wang, Jidong J. Yang
  • Methods and systems for crack detection using a fully convolutional network
    Patent number: 12039441
    Abstract: Systems and methods for detecting cracks in a surface by analyzing a video, including an full-HD video, of the surface. The video contains successive frames, wherein individual frames of overlapping consecutive pairs of the successive frames have overlapping areas and a crack that appears in a first individual frame of a consecutive pair of the successive frames also appears in at least a second individual frame of the consecutive pair. A fully convolutional network (FCN) architecture implemented on a processing device is then used to analyze at least some of the individual frames of the video to generate crack score maps for the individual frames, and a parametric data fusion scheme implemented on a processing device is used to fuse crack scores of the crack score maps of the individual frames to identify cracks in the individual frames.
    Type: Grant
    Filed: April 9, 2020
    Date of Patent: July 16, 2024
    Assignee: Purdue Research Foundation
    Inventors: Fu-Chen Chen, Mohammad R. Jahanshahi
  • Thin-film composite membrane and methods of making and using the same
    Patent number: 12036515
    Abstract: The present invention relates to a thin-film composite (TFC) membrane composition comprising macrocycles. The invention also relates in part to a method of fabricating a TFC membrane and to a method of using the TFC membrane to separate a desired liquid or gas from a liquid or gas mixture.
    Type: Grant
    Filed: October 2, 2019
    Date of Patent: July 16, 2024
    Assignee: THE PENN STATE RESEARCH FOUNDATION
    Inventors: Manish Kumar, Woochul Song, Yue-xiao Shen, Chao Lang
  • Purified exosome products, method of making, and methods of using
    Patent number: 12036325
    Abstract: A purified exosome product includes spherical or spheroid exosomes with a diameter no greater than 250 nm. In some embodiments, the purified exosome product has a moisture content of no more than 10%. The purified exosome product can be reconstituted to prepare an artificial blood product.
    Type: Grant
    Filed: December 14, 2018
    Date of Patent: July 16, 2024
    Assignee: MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH
    Inventors: Atta Behfar, Soulmaz Boroumand, Michael V. Callahan
  • Edible plant-derived nanoparticles for regulation of gut microbiota
    Patent number: 12036262
    Abstract: Provided are methods for modulating gut microbiota in subjects. In some embodiments, the methods include administering to a subject an effective amount of a composition that includes a first edible plant-derived nanoparticle encapsulating an effective amount of RNA. Also provided are methods for preventing and/or treating gut dysbiosis, methods for modulating bacterial growth, methods for modulating inflammatory cytokines, methods for reducing migration of bacterial from the gut to gut-associated bloodstream, and compositions for use in the presently disclosed methods, including pharmaceutical compositions.
    Type: Grant
    Filed: November 21, 2018
    Date of Patent: July 16, 2024
    Assignee: University of Louisville Research Foundation, Inc.
    Inventor: Huang-Ge Zhang
  • Heterobiaryl compounds and imaging agents for imaging huntingtin protein
    Patent number: 12036292
    Abstract: Provided herein are certain compounds and imaging agents useful for detecting a disease or condition associated with protein aggregation, compositions thereof, and methods of their use.
    Type: Grant
    Filed: August 5, 2021
    Date of Patent: July 16, 2024
    Assignee: CHDI Foundation, Inc.
    Inventors: Longbin Liu, Celia Dominguez, Xuemei Chen, John E. Mangette
  • Endoscope for tissue dissection and visualization
    Patent number: 12035882
    Abstract: One aspect of the present disclosure relates to an endoscope for facilitating a medical procedure by creating an anatomic space in or adjacent a target bodily tissue to be imaged. The endoscope can comprise a flexible, elongate tubular member defining a central lumen and an expandable dissecting member coupled to a distal end of the tubular member. The tubular member can further include at least one imaging channel extending longitudinally therethrough. The at least one imaging channel can include a visualization system for conveying an image from the distal end of the tubular member to a user. The expandable dissecting member can define a channel in fluid communication with the central lumen of the tubular member. The expandable dissecting member can extend beyond the distal end of the tubular member.
    Type: Grant
    Filed: March 3, 2022
    Date of Patent: July 16, 2024
    Assignee: THE CLEVELAND CLINIC FOUNDATION
    Inventor: Francis A. Papay
  • Method of producing hydrogen using biomass
    Patent number: 12037243
    Abstract: A method of producing hydrogen using biomass includes: pretreating the biomass using an ionic liquid; and extracting hydrogen by reacting the pretreated biomass with an alkaline substance.
    Type: Grant
    Filed: June 7, 2021
    Date of Patent: July 16, 2024
    Assignees: Hyundai Motor Company, Kia Corporation, EWHA University—Industry Collaboration Foundation
    Inventors: Dong Seok Ko, Woo Jae Kim, Hye Min Jung
  • Artificial intelligence-based oral CT automatic color conversion device and method for driving same
    Patent number: 12036060
    Abstract: The present disclosure relates to an artificial intelligence-based oral CT automatic color conversion device and a method for driving same. The artificial intelligence-based oral CT automatic color conversion device according to an embodiment of the present invention comprises: a storage unit which stores a color conversion image related to the bone density of an alveolar bone, which is previously prepared by a user; and a control unit which, when an oral CT input image of a patient is received, converts color of the received oral CT input image on the basis of a predetermined parameter value, and adjusts the predetermined parameter value by using an error value resulting from the converted oral CT input image and the (pre)stored color conversion image to automatically convert the color of an oral CT input image to be input later.
    Type: Grant
    Filed: October 8, 2020
    Date of Patent: July 16, 2024
    Assignees: MEGAGEN IMPLANT CO., LTD., KYUNGPOOK NATIONAL UNIVERSITY HOSPITAL, KYUNGPOOK NATIONAL UNIVERSITY INDUSTRY-ACADEMIC COOPERATION FOUNDATION
    Inventors: Kwang Bum Park, Keun Oh Park, Tae Gyoun Lee, Sung Moon Jeong, Dong Won Woo
  • Fibers having electrically conductive core and color-changing coating
    Patent number: 12037710
    Abstract: A method of manufacturing a color-changing fiber includes loading a polymeric material and a thermochromic pigment material into a fiber fabrication machine that comprises an extruder and a spinneret, operating the extruder to provide a molten mixture of the polymeric material and the thermochromic pigment material, providing a volume of the molten mixture to the spinneret, and operating the spinneret to coat an electrically conductive core with the molten mixture to form a coating layer around the electrically conductive core to produce the color-changing fiber. The polymeric material and the thermochromic pigment material are provided as (a) a first raw material comprising the polymeric material and a second raw material comprising the thermochromic pigment material or (b) a thermochromic pigment and polymer mixture.
    Type: Grant
    Filed: April 13, 2020
    Date of Patent: July 16, 2024
    Assignee: UNIVERSITY OF CENTRAL FLORIDA RESEARCH FOUNDATION, INC.
    Inventors: Ayman Abouraddy, Joshua Kaufman, Felix Tan, Morgan Monroe