Abstract: A method of making curcuminoids in a mammalian cell. The method of making a curcuminoid in a mammalian cell includes expressing one or more enzymes in the mammalian cell, the enzymes being selected from the group consisting of tyrosine ammonia lyase (TAL), 4-coumaroyl-CoA ligase (4CL1), curcuminoid synthase (CUS), diketide-CoA synthase (DCS), curcumin synthase (CURS1), 4-coumarate 3-hydroxylase (C3H), caffeoyl-CoA 3-O-methyltransferase (CCoAMT), and acetyl-CoA carboxylase (ACC). The expressing of the one or more enzymes converts a starting material, such as tyrosine or ferulic acid, to the curcuminoid. Also provided herein are therapeutic uses for the curcuminoid made in a mammalian cell.

Abstract: A condensed cyclic compound and an organic light-emitting device including the condensed cyclic compound are provided. The condensed cyclic compound is represented by Formula 1. The A3 ring of Formula 1 is a group represented by Formula 2A or a group represented by Formula 2B. The organic light-emitting device includes: a first electrode; a second electrode; and an organic layer between the first electrode and the second electrode and including an emission layer, the organic layer including at least one of the condensed cyclic compound represented by Formula 1.

Abstract: A tissue collection and processing system for collecting bone fragments and tissue aspirated from a bone. The tissue collection and processing system includes a collection vessel, a collection vessel cap, a processing piston, a first tubing and a fluid withdrawal mechanism. The collection vessel has an opening formed therein to receive bone fragments and tissue aspirated from the bone. The collection vessel cap is capable of engaging the collection vessel to substantially seal the opening. The collection vessel cap or the collection vessel has a first port. The processing piston has an upper surface and a lower surface. The processing piston has a connection port and a bore. The connection port is proximate the upper surface. The bore is fluidly connected to the connection port and extends toward the lower surface. The processing piston has a density that is less than a density of fluid in the aspirated bone fragments and tissue.

Abstract: According to the present exemplary embodiments, provided are a traffic signal system and a vehicle which estimate a position and a moving direction of a vehicle in accordance with a driving status of the vehicle at an intersection and improve a positioning accuracy based on wired or wireless communication.

Abstract: Disclosed are a method and apparatus for processing source data of a synthetic aperture radar in a satellite, including receiving source data generated based on a signal returned after an electronic device steers a beam from a synthetic aperture radar and backscatters, setting a plurality of subswaths after the electronic device parses the source data, storing based on the plurality of subswaths after the electronic device decodes the source data; and generating image data after the electronic device calls the decoded source data in the order of the plurality of subswaths.

Abstract: A method of evaluating quality of graphene using a confocal laser scanning microscope, the method comprising steps of: irradiating with laser light a graphene layer formed on a catalyst layer; detecting a signal of light reflected from the graphene layer; forming a planar image of the graphene layer using the detected optical signal; and analyzing a contrast between graphene and the catalyst layer in the planar image, wherein the graphene layer is continuously formed on the catalyst layer by a roll-to-roll process.

Abstract: The present invention relates to a method and apparatus for handling personal data in a machine-to-machine (M2M) system, and an operation method of an M2M device includes obtaining information related to consent of a user for personal data provided from an Internet of things (IoT) device and creating a consent-related resource based on the information. The resource includes at least one attribute related to the consent.

Abstract: A clock transfer circuit includes a first stage circuit configured to produce an output signal that uses a second signaling technology from an input signal that uses a first signaling technology; and a second stage circuit configured to produce a clock signal by delaying the output signal; wherein the first stage circuit includes a semiconductor device configured to compensate for delay fluctuation caused by fluctuation of power supply voltage between a first power source and a second power source.

Abstract: A locking device includes a lock body configured to be secured to a part of a bicycle, a cable within the lock body and having a first end accessible from an exterior of the lock body, a spring coil mechanism within the lock body for coiling the cable within the lock body and enabling the cable to be selectively extended from the lock body to lock the bicycle to a separate structure by wrapping the cable around the separate structure and then locking the first end of the cable to the lock body, and a communication and control unit incorporated into the lock body and configured to communicate with a remote device to allow the remote device to wirelessly unlock the first end of the cable from the lock body.

Abstract: This document provides methods and materials related to vesicular stomatitis viruses. For example, vesicular stomatitis viruses, nucleic acid molecules encoding VSV polypeptides, methods for making vesicular stomatitis viruses, and methods for using vesicular stomatitis viruses to treat cancer are provided.

Abstract: A method and device for a power saving operation in a communication system supporting multiple links includes a method of a first device including the steps of performing a PS setting procedure with a second device; generating a first frame including a first data unit, for initiating a transmission operation according to the PS setting procedure; and transmitting the first frame to the second device in a first link mapped to the first data unit among multiple links set between the first device and the second device.

Abstract: The disclosure relates to compounds of Formula (I), as well as compositions, methods, uses, and kits comprising the same. The compounds, compositions, methods, uses, and kits provided herein are useful in treating diseases or disorders including cancer, HIV, and angiogenesis-related disorders.

Abstract: Methods of treating the effects of disruption of normal blood flow in the CNS in an individual subject in need thereof are provided according to aspects of the present invention which include administering a therapeutically effective dose of exogenous NeuroD1 to an area where normal blood flow has been disrupted. Compositions are provided including 1) a recombinant adeno-associated adenovirus expression vector comprising a glial cell specific promoter operably linked to a nucleic acid encoding a site-specific recombinase and 2) a recombinant adeno-associated adenovirus expression vector comprising a ubiquitous promoter operably linked to a nucleic acid encoding NeuroD1, wherein the nucleic acid encoding NeuroD1 is inverted and flanked by two sets of site-specific recombinase recognition sites such that action of the recombinase irreversibly inverts the nucleic acid encoding NeuroD1 such that NeuroD1 is expressed in a mammalian cell.

Abstract: Disclosed is a wireless power transfer pairing method and apparatus for concurrently performing a pairing procedure in a V2G WPT fine positioning procedure. The wireless power transfer pairing method comprises a step of, when an LF signal indicating that a secondary device of an electric vehicle is positioned within an alignment tolerance area on a primary device of an electric vehicle power supply device is detected, parking the electric vehicle, transmitting, to a supply equipment communication controller (SECC), a fine positioning request message in which a result code parameter is configured as a success, and transmitting, immediately after receiving from the SECC, a fine positioning response message in which a response code parameter is configured as OK, a pairing request message in which an identifier code parameter is configured as a pairing identification code and an EV processing parameter is configured as termination, to the SECC.

Abstract: The present invention relates to a method of treatment for chronic pain, opioid dependence, alcohol use disorder or autism using a class of pyrimidinone compounds, an adenylyl cyclase 1 (AC1) inhibitor. The invention described herein also pertains to pharmaceutical compositions and methods for treating diseases in mammals using those compounds disclosed herein.

Abstract: A semiconductor system including a transmitter configured to output a plurality of data as a plurality of data input/output signals through a plurality of channels based on a matrix E, and a receiver configured to generate the plurality of data by differentially amplifying the plurality of data input/output signals received through the plurality of channels based on a matrix D, in which all components of the matrix E and the matrix D are integers, a product matrix of the matrix D and the matrix E is a diagonal matrix, a sum of the components of each row of the matrix D is 0, and a sum of absolute values of the components of each column of the matrix D is less than or equal to a threshold value.

Abstract: A display device according to an exemplary embodiment of the present disclosure includes a light emitting diode and a pixel driving circuit which drives the light emitting diode, the pixel driving circuit includes a driving transistor which applies a driving current to the light emitting diode, a first transistor which applies a first reference voltage to a gate electrode of the driving transistor, a second transistor which applies a data voltage to the gate electrode of the driving transistor, a third transistor which applies a second reference voltage to a source electrode of the driving transistor, and a storage capacitor connected to the gate electrode and the source electrode of the driving transistor. According to the present disclosure, the threshold voltage Vth and the mobility of the driving transistors are internally compensated to improve an image quality.

Abstract: Disclosed herein is an elevator landing control system according to various embodiments of the present disclosure for achieving the above-described objects. The elevator landing control system includes an upper frame provided in an upward direction of a cage and provided with a main rope connected thereto, a position adjusting device connecting the cage and the upper frame, and a sensor device configured to detect a landing error between a floor of the cage and a floor of a platform, wherein the position adjusting device may adjust a distance between the upper frame and the cage based on the landing error detected from the sensor device to correct a height of the cage.

Abstract: Provided are compositions and methods for treating and/or preventing seizure-induced death in subjects in need thereof. In some embodiments, the methods include methods for inducing an audiogenic seizure and/or seizure-induced death, treating and/or preventing death associated with seizures in subjects, preventing sudden unexpected death in epilepsy (SUDEP) in subjects, preventing and/or reducing the risk of death in subjects having SCN8A gain-of-function mutations, preventing or reducing the risk of death associated with tonic seizures in subjects, and preventing or reducing the risk of death associated with epileptic seizures in subjects. Also provided are animals that have been modified to carry gain-of-function SCN8A mutations and methods for using the same to identify compounds that have activity in treating and/or preventing seizures and/or seizure-induced death in subjects.

Abstract: Disclosed are a three-dimensional flash memory for improving contact resistance of IGZO channel layer and a method for manufacturing same. According to one embodiment, the three-dimensional flash memory may comprise: multiple word lines sequentially stacked and extending in a horizontal direction on a substrate; and at least one string extending in a vertical direction on the substrate through the multiple word lines, the at least one string comprising a channel layer extending in the vertical direction and a charge storage layer formed to surround the channel layer, wherein the at least one string comprises a drain junction formed in a dual structure and comprising an N+ doped first area on the channel layer and an N+ doped second area with a material having lower contact resistance than the channel layer.