Abstract: [Problem] The present invention provides a novel pathological marker of angiitis which serves as an alternative to MPO-ANCAs. [Means for Solution] According to one embodiment of the present invention, a method for testing angiitis which includes a step of detecting an antibody specifically recognizing a moesin in a biological sample is provided. In addition, according to another embodiment of the present invention, a reagent for testing angiitis which contains a substance that detects an antibody specifically recognizing a moesin in a biological sample is provided.

Abstract: Methods and compositions involving miR-122, miR-15b, miR-21, and miR-155, which are useful for the treatment of various diseases, such as cancers, are described. Further described are methods and compositions useful for increasing, activating, or regulating NK cells and surface antigens.

Abstract: Disclosed is a dual aperture camera which includes a dual band filter and a CMOS image sensor (CIS). The dual band filter is adapted to filter light signals to receive a light signal of a first wavelength range and receive a light signal of a second wavelength range through a pin hole included therein. The CIS is adapted to process the light signal of the first wavelength range and the light signal of the second wavelength range received through the dual band filter.

Abstract: The present invention provides methods and compositions for treating and/or preventing age related macular degeneration and other conditions involving macular degeneration, ocular neovascularization, or ocular inflammation. In an exemplary embodiment, a method is disclosed that involves administering an expression vector that delivers a secretable and cell penetrating CARD to a subject in need of treatment or prevention of age-related macular degeneration or another condition involving macular degeneration or ocular neovascularization.

Abstract: The present invention relates to pharmaceutical compositions for treating cancer comprising BRAF inhibitors, (e.g. vemurafenib) and/or MEK inhibitor, (e.g. trametinib, RO5068760), in combination with anti-tubulin compounds of the invention or other known tubulin inhibitors, and using such compositions for treating cancer such as melanoma, drug-resistant cancer, and cancer metastasis.

Abstract: A method for controlling flow localization in machining process is disclosed. By application of a constraint of sufficient level in the deformation zone and modifying the surface boundary conditions, suppression of unsteady flow and flow instabilities is achieved. The method enhances machined component quality by ensuring a uniform deformation state on the machined surface. Machined components are produced by ensuing uniform deformation by adopting constrained-cutting process for suppressing the instabilities and unsteady flow through a pre-determined location of the constraint of the constrained machining process relative to the machining tool.

Abstract: An electronic element is provided. The electronic element may include a hybrid electrode having a high work function and conductivity which has a conductivity of at least 1 S/cm and includes: a work function-tuning layer; and a conductivity-tuning layer which is in contact with the first surface of the work function-tuning layer. Accordingly, the electronic element which employs the hybrid electrode having a high work function and conductivity may have excellent light-emitting efficiency and/or photoelectric conversion efficiency even if a hole injection layer for work function adjustment is omitted.

Abstract: A mechanochemical oxidation process that allows relatively benign oxidizers to be used for the production of at least partially oxidized graphite, and a method of preparing a carbon fiber using oxidized graphite and a fiber component. Partially oxidized graphite is fully dispersible in water and can be used to prepare thin films with conductivities rivaling pure graphite. This offers the potential for improved electronic displays, solar cells, and lithium ion batteries. A carbon nanotube and a method of making the same is also provided.

Abstract: The present invention relates to a HSP27 mutation (S135F) mediated Charcot-Marie-Tooth disease (CMT) animal model. Particularly, the vector expressing mutant HSP27 protein wherein the 135th serine is substituted with phenylalanine has been injected in the mouse zygote and then the mouse harboring the expression vector was selected. The selected mouse was confirmed to display Charcot-Marie-Tooth disease phenotype, so that the animal model was expected to be efficiently used for the evaluation of the effect of Charcot-Marie-Tooth disease treating material candidates.

Abstract: An electronic shelf label gateway may include a data storing unit storing original data, a signal processing unit generating an encoded data packet by encoding the original data, a controlling unit controlling transmission of the encoded data packet so as to sequentially perform a first multicast, a second multicast, and a unicast of the encoded data packet until all of a plurality of connected electronic shelf label devices successfully receive the encoded data packet, and a communicating unit wirelessly transmitting the encoded data packet according to controlling by the controlling unit.

Abstract: The present invention relates to a marker which can be used to diagnose a diabetic retinopathy patient and determine the progression of diabetic retinopathy, a composition for diagnosing diabetic retinopathy, which comprises an agent for measuring the level of a gene or protein associated with the marker, and the use thereof.

Abstract: Various examples are provided for operational control of fuel cells. In one example, among others, a system for controlling a fuel cell includes a stack temperature controller in cascade with a liquid level controller. The liquid level controller can provide a control output based at least in part upon an indication of a liquid level of a liquid fuel tank and a level reference. The stack temperature controller can provide a fan speed control output based at least in part upon an indication of a stack temperature of the fuel cell and the control output of the liquid level controller. In another example, a system for estimating methanol concentration of a fuel cell system includes a state observer that generates an estimate of the methanol concentration of fuel provided to a direct methanol fuel cell based upon a plurality of states of the fuel cell system.

Abstract: Disclosed herein are methods and materials that may be implemented to scavenge a potentially destructive free radical, peroxynitrite. Specifically exemplified are cerium based nanoparticles that react with and reduce peroxynitrite. The discoveries disclosed herein reveal several therapeutic uses of such peroxynitrite reactive particles.

Abstract: Provided is a ramp tag capable of solving instability in translation rate resulting from poor compatibility between codons in a foreign gene and a host when expressing a recombinant protein in E. coli. Unlike the conventional codon optimization or codon deoptimization method for solving the problem of rare codons, the present invention increases an expression efficiency of a target protein by merely having the ramp tag be fused with a target gene or independently expressed, without changing the original codon sequence, thereby allowing tRNA to be reused. Thus, the present invention provides a novel method for increasing recombinant protein expression which is capable of reducing costs and time in comparison to the codon optimization method that artificially synthesizes DNA sequences. Therefore, it is expected that the method of the present invention will be able to be used in production of high value-added pharmaceuticals or industrial enzymes.

Abstract: A system for extraction of cells from a sample of tissue comprises a main device (1) and a disposable kit (4) for use with said main device; said main device (1) is configured to host at least one disposable kit and to execute at least one preset program; said disposable kit (4) comprises a work chamber (11) for the sample of tissue and a plurality of solution bags (12), the disposable kit comprises also fluid transfer means (14, 19) operating between the work chamber and the solution bags (12) and controlled by the main device via suitable interface means; in a preferred embodiment the disposable kit (4) is mounted on a drum and contained in an active capsule carried by a rotary carousel; claims are also directed to the disposable kit for use in said system.

Abstract: An anion exchange method using an anion exchange precursor based on a metal-chalcogenide compound is provided. The anion exchange method includes exchanging an anionic element of a nanoparticle with an element X of an anion exchange precursor represented by Na2Xn via a reaction between the anion exchange precursor and the nanoparticle in the presence of a reaction medium, wherein X is at least one element selected from the group consisting of Se, S, and Te, and n is an integer from 2 to 10.

Abstract: The subject invention provides therapeutic compositions and uses thereof for improving pulmonary function. In one embodiment, the therapeutic composition comprises one or more free amino acids selected from lysine, glycine, threonine, valine, tyrosine, aspartic acid, isoleucine, tryptophan, asparagine, and serine; and electrolytes. In one embodiment, the subject invention can be used to prevent or treat long-term lung complications induced by radiation.

Abstract: A compound, an organic light-emitting device, and a flat display apparatus, the compound being represented by Formula 1, below:

Abstract: Lipid nanoparticle formulations, methods of making, and methods of using same are disclosed.

Abstract: An apparatus configured to control a heat flow is provided. The apparatus may include a semiconductor device region formed in a matrix; a heat rectifier region formed adjacent to the semiconductor device region; and a heat flow blocker formed in at least one region contacting the semiconductor device region and the heat rectifier region.