Patents Assigned to Foundation
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Publication number: 20100066506Abstract: A system provides for remote monitoring using asynchronous code division multiple access (CDMA) communication techniques between a base station and one or more transponders. Each transponder is attached or otherwise associated with an object or an environment to be monitored. Upon receipt of an interrogation signal, a transponder generates and transmits a coded transponder signal containing the monitored data. The coded transponder signal is generated using a spreading code. Each transponder is associated with a unique, mutually exclusive set of spreading codes. Each spreading code is based on a unique transponder address and the monitored data to be sent. A detector asynchronously monitors received signals for any of the available spreading codes. Once the detector detects a particular spreading code, the base station can identify the source transponder and extract the monitored data.Type: ApplicationFiled: November 20, 2009Publication date: March 18, 2010Applicant: Mayo Foundation for Medical Education and ResearchInventors: Timothy Michael Schaefer, Jonathan Darrel Coker, Rick Allen Philpott, Edward Brian Welch, David R. Holmes, III
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Publication number: 20100067997Abstract: An apparatus for drilling a workpiece has a shaft portion including a holder to hold a drilling tool rotating around a first axis. A reduction gear is connected to the shaft portion. A cylindrical member, including an outer cylinder and an inner cylinder, rotatably contains the shaft portion at an eccentric position. The cylindrical member is connected to the output shaft of the reduction gear and rotated around a second axis parallel to the first axis. A slide containing cylinder contains the shaft portion, the reduction gear and the cylindrical member. The slide containing cylinder has a sliding structure for axially moving the shaft portion, the reduction gear and the cylindrical member. A drilling tool is simultaneously rotated around the first axis, revolved around the second axis and is axially moved.Type: ApplicationFiled: November 18, 2009Publication date: March 18, 2010Applicant: Hamamatsu Foundation for Science and Technology FoundationInventor: Hukuzo Yagishita
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Patent number: 7680526Abstract: This document discusses, among other things, brain stimulation models, systems, devices, and methods, such as for deep brain stimulation (DBS) or other electrical stimulation. A model computes a volume of influence region for a simulated electrical stimulation using certain stimulation parameters, such as amplitude, pulsewidth, frequency, pulse morphology, electrode contact selection or location, return path electrode selection, pulse polarity, etc. The model uses a non-uniform tissue conductivity. This accurately represents brain tissue, which has highly directionally conductive neuron pathways yielding a non-homogeneous and anisotropic tissue medium. In one example, the non-uniform tissue conductivity is obtained from diffusion tensor imaging (DTI) data. In one example, a second difference of an electric potential distribution is used to define a volume of activation (VOA) or similar volume of influence.Type: GrantFiled: January 14, 2008Date of Patent: March 16, 2010Assignee: The Cleveland Clinic FoundationInventors: Cameron C. McIntyre, Christopher R. Butson, John D. Hall, Jaimie M. Henderson
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Patent number: 7680200Abstract: Disclosed is a transceiving apparatus and method in which a space frequency block coding (SFBC) technique is applied to the SC-FDE technique. The transceiving method encodes an input signal into frequency-domain blocks so as to output at least two signal blocks in parallel to each other, inserts a cyclic prefix (CP) into the output signal blocks, and outputs the signal blocks through the same sub-channel using a corresponding antenna.Type: GrantFiled: March 23, 2006Date of Patent: March 16, 2010Assignees: Samsung Electronics Co., Ltd, Postech FoundationInventors: Jong-Hyung Kwun, Eung-Sun Kim, Jong-Hyeuk Lee, Gi-Hong Im, Hui-Chul Won, Jin-Ho Jang
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Patent number: 7678838Abstract: A method of preparing nanothin polymer films having uniform and selectively sized pores utilizing pore forming templates. Lipids and pore forming templates are dissolved into a first solution. The solvent is removed thereby creating a lipid bilayer with pore forming templates dispersed throughout. The bilayer is hydrated and monomers and crosslinkers are added to create a second solution. A nanothin film with pore forming templates is created through polymerization of said second solution. The pore forming templates are dissolved into a third solution by addition of a chemical in which the pore forming template is soluble, but the lipid bilayer is insoluble. This third solution is separated from the mixture leaving a nanothin polymer film with pores of a uniform thickness and surface area.Type: GrantFiled: August 2, 2007Date of Patent: March 16, 2010Assignee: University of Memphis Research FoundationInventors: Evgueni Pinkhassik, Delia Cesara Danila, Larry Todd Banner
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Patent number: 7678570Abstract: A novel human cell strain enabling the continuous production of a desired protein with high efficiency, comprising a novel human cell strain established by transforming a human cell strain whose total intracellular protein weight is 0.1 to 1 mg per 1,000,000 cells; with the novel human cell strain being further characterized in that after a gene encoding a desired protein is transfected into it, the transfected cell is subsequently cultured.Type: GrantFiled: October 27, 2004Date of Patent: March 16, 2010Assignee: Kitakyushu Foundation for the Advancement of Industry, Science and TechnologyInventor: Hiroharu Kawahara
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Patent number: 7679867Abstract: A magnetic flux coupling-type superconducting current limiter is capable of protecting lines more effectively by winding reactors of a primary coil and a secondary coil in series in the structure where the primary coil and the secondary coils are wound in parallel in the conventional magnetic flux-lock type current limiter to increase a linked flux generated from an iron core. An electric conducting current which rapidly increases when a fault occurs is divided into the secondary coil and a superconducting coil to decrease a load on the superconducting element and it is opened more rapidly than the existing superconducting current limiter during a quench time such that it better limits a fault current.Type: GrantFiled: March 30, 2007Date of Patent: March 16, 2010Assignee: Industry-Academic Cooperation Foundation, Chosun UniversityInventors: Hyo-Sang Choi, Hyoung-Min Park, Yong-Sun Cho, Gueng-Hyun Nam, Na-Young Lee, Tae-Hee Han, Sung-Hun Lim, Dong-Chul Chung
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Patent number: 7678556Abstract: The present invention relates to an isolated ?-mannanase protein having an amino acid sequence which is 90% similar to the amino acid sequence of SEQ ID NO:1, as well as isolated polynucleotides encoding the ?-mannanase protein, and isolated expression systems and host cells containing the polynucleotides. The present invention also relates to a method of recombinantly producing ?-mannanase protein. Also disclosed is a method of degrading mannans and polysaccharides in plant material, which involves providing plant material and contacting the plant material with the ?-mannanase protein of the present invention under conditions effective to degrade mannans and polysaccharides in the plant material.Type: GrantFiled: November 20, 2007Date of Patent: March 16, 2010Assignees: Cornell Research Foundation, Inc., Federacion Nacional de Cafeteros de ColombiaInventors: Jocelyn Rose, Ricardo Acuña
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Patent number: 7678064Abstract: An apparatus for helping to determine tactile sensitivity of a patient includes a housing and a probe supported by the housing and having a probe tip. The probe is adapted for selective longitudinal movement relative to the housing between a first probe position, wherein the probe tip is substantially extended from the housing, and a second probe position, wherein the probe tip is substantially retracted into the housing. A first biasing means is adapted to urge the probe toward the first probe position. A predetermined motive force is selectively exerted between the probe tip and the patient to move the probe from the first probe position to the second probe position. The motive force is indicative of tactile sensitivity of the patient. A method for helping to determine tactile sensitivity of a patient is also described.Type: GrantFiled: October 18, 2007Date of Patent: March 16, 2010Assignee: The Cleveland Clinic FoundationInventor: Barry D. Kuban
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Patent number: 7678549Abstract: Aggressive human tumor cells from disparate tissues were found to secrete nucleoside diphosphate kinase-B (NDPK-B) as a phosphoprotein into the extracellular environment. The secreted enzyme was capable of trasphosphorylation activity in the absence of a phosphoryl donor, thereby producing elevated level of extracellular ATP that plays a significant role in angiogenesis required for the growth of cancer cells and cancer metastasis. A series of structurally related non-nucleotide anticancer compounds such as ellagic acid (EA), epigallocatechin gallate (EGCG), and epicatechin gallate (ECG) were found to inhibit the activity of secreted nucleoside diphosphate kinase-B as well as angiogenesis. The nucleoside diphosphate kinase-B inhibition data disclosed herein can be used in predicative models to design novel inhibitors of nucleoside diphosphate kinase-B activity.Type: GrantFiled: December 30, 2002Date of Patent: March 16, 2010Assignee: Research Development FoundationInventor: Iain Buxton
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Patent number: 7678063Abstract: A bellows-based patient breath-hold monitoring and feedback system for use in intermittent mode CT fluoroscopy-guided biopsies of the lung or upper abdomen where respiratory motion is a problem. Breath-hold monitoring and feedback with the bellows system allows a patient to perform consistent breath-holds at a preselected level, which in turn, optimizes intermittent mode CT fluoroscopy-guided biopsies of the lung or upper abdomen by allowing target lesions to be reliably visualized.Type: GrantFiled: December 13, 2006Date of Patent: March 16, 2010Assignee: Mayo Foundation for Medical Education and ResearchInventors: Joel P. Felmlee, Russell E. Bruhnke, Phillip Rossman, James P. Potter, Sr., Stephanie K. Carlson
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Patent number: 7678946Abstract: Trisubstituted phenol compounds and methods of using the compounds, e.g., for anesthetizing a subject, are disclosed.Type: GrantFiled: July 13, 2007Date of Patent: March 16, 2010Assignee: University of Iowa Research FoundationInventor: Max T. Baker
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Patent number: 7679884Abstract: Disclosed are electrolytes that are organosilicon phosphorus-based, and supercapacitors which incorporate them. These electrolytes are cationic salts with a phosphorous containing organosilicon moiety. They appear particularly suitable for use in applications such as electric and hybrid electric vehicles.Type: GrantFiled: July 29, 2008Date of Patent: March 16, 2010Assignee: Wisconsin Alumni Research FoundationInventors: Robert C. West, Lingzhi Zhang
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Patent number: 7678545Abstract: The present invention is directed to methods for providing a polyelectrolyte multilayer film at a liquid-liquid interface. Such methods include steps of sequentially-depositing layers of cationic and anionic polyelectrolytes at a liquid-liquid interface that is formed between immiscible first and second liquids whereby a polyelectrolyte multilayer film is provided at the liquid-liquid interface. In certain preferred embodiments, the first liquid is an aqueous solution and the second liquid is a liquid crystal. In alternative embodiments, the first liquid is an aqueous solution and the second liquid is an oil. The invention further encompasses polyelectrolyte multilayer films provided by the disclosed methods as well as applications utilizing such materials.Type: GrantFiled: July 10, 2006Date of Patent: March 16, 2010Assignee: Wisconsin Alumni Research FoundationInventors: Nicholas Abbott, Nathan A. Lockwood, Katie D. Cadwell, Frank Caruso, Elvira Tjipto
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Patent number: 7678546Abstract: Disclosed is a method for detection of ligand-cell membrane protein binding by solid state NMR spectroscopy. The method starts by forming a lipid bilayer inside nanopores of an anodic aluminum oxide (AAO) substrate, the lipid bilayer containing a membrane protein sample. The AAO substrate is treated with multiple candidate ligands having potential binding affinity for the membrane protein. Solid-state NMR analysis is performed on the treated AAO/lipid preparation so as to generate an NMR spectrum for the treated membrane protein. The solid-state NMR spectrum of the treated membrane protein is compared with the spectrum of the same preparation of membrane protein in the absence of the ligands. It is then determined whether the solid-state NMR spectrum of the treated membrane protein has shifted from the NMR spectrum of the untreated membrane protein, a shift being indicative of protein binding by the candidate ligand.Type: GrantFiled: October 1, 2007Date of Patent: March 16, 2010Assignee: The Florida State University Research Foundation, Inc.Inventors: Timothy Cross, William W. Brey, Alexej Smirnov, Eduard Y Chekmenev
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Patent number: 7679615Abstract: Systems and methods for computing three-dimensional (3D) Euclidean Voronoi diagrams are disclosed. For some embodiments, a set of 3D objects is accessed, in which each 3D object is mathematically defined. Thereafter, a Voronoi region associated with each of the 3D objects is computed, thereby resulting in a complete Euclidean Voronoi diagram of the set of 3D objects. In some embodiments, the 3D objects are spheres, each of which is defined by a center and a radius. For other embodiments, the 3D objects are convex objects, each of which is mathematically-definable (e.g., cylinders, sphero-cylinders, etc.). Unlike prior approaches that suggested using a numerical approach to computing the Voronoi diagram, the present disclosure employs mathematical approaches for computing the Euclidean Voronoi diagram, thereby improving efficiency in the computation of the Euclidean Voronoi diagram.Type: GrantFiled: May 3, 2005Date of Patent: March 16, 2010Assignee: IUCF-HYU (Industry-University Cooperation Foundation Hanyang University)Inventors: Deok-Soo Kim, Youngsong Cho, Donguk Kim
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Patent number: 7679058Abstract: Methods and systems related to soil testing are disclosed. One exemplary embodiment of a system of the present disclosure includes a calibrated near-infrared (NIR) spectrophotometer and a soil sample with an unknown value of at least one of pH and b disposed in proximity to the calibrated NIR spectrophotometer, the NIR spectrophotometer configured to produce a spectrum from a reading of the sample.Type: GrantFiled: December 15, 2005Date of Patent: March 16, 2010Assignee: The University of Georgia Research Foundation, Inc.Inventors: David E. Kissel, Miguel L. Cabrera
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Patent number: 7678760Abstract: Methods for the production of purified, catalytically active, recombinant memapsin 2 have been developed. The substrate and subsite specificity of the catalytically active enzyme have been determined. The substrate and subsite specificity information was used to design substrate analogs of the natural memapsin 2 substrate that can inhibit the function of memapsin 2. The substrate analogs are based on peptide sequences, shown to be related to the natural peptide substrates for memapsin 2. The substrate analogs contain at least one analog of an amide bond which is not capable of being cleaved by memapsin 2. Processes for the synthesis of two substrate analogues including isosteres at the sites of the critical amino acid residues were developed and the substrate analogues, OMR99-1 and OM99-2, were synthesized. OM99-2 is based on an octapeptide Glu-Val-Asn-Leu-Ala-Ala-Glu-Phe (SEQ ID NO:28) with the Leu-Ala peptide bond substituted by a transition-state isostere hydroxyethylene group (FIG. 1).Type: GrantFiled: June 14, 2007Date of Patent: March 16, 2010Assignees: The Board of Trustees of the University of Illinois, Oklahoma Medical Research FoundationInventors: Jordan J. N. Tang, Arun K. Ghosh
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Patent number: 7679563Abstract: An improved frequency selective surface (FSS) comprises a periodically replicated unit cell, the unit cell including a material having a first electrical conductivity in the presence of an external condition, and a second electrical conductivity in the absence of an external condition, or in the presence of a modified external condition. For example, the material may be a chemoresistive material, having an electrical conductivity that changes in the presence of a chemical or biological analyte, i.e. having a first value of electrical conductivity in the presence of the analyte, and a second value of electrical conductivity in the absence of the analyte.Type: GrantFiled: January 14, 2005Date of Patent: March 16, 2010Assignee: The Penn State Research FoundationInventors: Douglas H. Werner, Theresa S. Mayer, Jeremy A. Bossard, Robert P. Drupp, Xiaotao Liang, Ling Li
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Patent number: 7680757Abstract: A method for discovering association rules in a distributed database that includes a plurality of partitions associated with respective computing nodes includes generating a candidate association rule defining an association relationship between itemsets in the distributed database. At each node among at least a subset of the nodes, an asynchronous fully-distributed majority voting process is applied to assess a correctness of the candidate association rule.Type: GrantFiled: November 9, 2005Date of Patent: March 16, 2010Assignee: Technion Research & Development Foundation Ltd.Inventors: Ran Wolff, Assaf Schuster