Patents Assigned to Foundation
  • IMPLANTABLE MEDICAL DEVICE CHARGERS AND CHARGER POSITIONING SUPPORTS FOR USE WITH SAME
    Publication number: 20230293896
    Abstract: An implantable medical device (IMD) charger apparatus may include an IMD charger including a housing defining a bottom surface, a primary coil located within the housing, and a fastener on the bottom surface of the housing, and a charger support, mounted on the IMD charger, including a bottom surface, and movable between a first state and a second state. The IMD charger and the charger support may be respectively configured such that the IMD charger fastener is above the charger support bottom surface when the charger support is in the first state and the IMD charger fastener is at or below the charger support bottom surface when the charger support is in the second state.
    Type: Application
    Filed: February 27, 2023
    Publication date: September 21, 2023
    Applicant: The Alfred E. Mann Foundation for Scientific Research
    Inventors: Joseph L. Calderon, Edward Hillery, Susanna M. Lin
  • CHIMERIC ANTIGEN RECEPTORS AND USES THEREOF
    Publication number: 20230295319
    Abstract: Aspects of the disclosure relate to chimeric antigen receptors (CARs) comprising an antigen binding domain (e.g., anti-TSHR), transmembrane domain (e.g., CD28), and a cytoplasmic domain (e.g., CD27, CD-137, etc.) and a safety mechanism comprising an inducible apoptosis trigger. In some aspects, the disclosure relates to use of the CARs in T cells, compositions, kits and methods for the treatment of thyroid cancers.
    Type: Application
    Filed: March 6, 2023
    Publication date: September 21, 2023
    Applicant: University of Florida Research Foundation, Incorporated
    Inventors: Scott A. Rivkees, Christopher Wendler, Lung-Ji Chang
  • NEURAL NETWORK BASED METHOD AND DEVICE
    Publication number: 20230298663
    Abstract: A neural network method and device are included, A neural network circuit includes a synaptic memory cell including a resistive memory element, which is disposed along an output line and which can have a first resistance value and a second resistance value as a resistance value, the synaptic memory cell generates a column signal, based on the resistance value of the resistive memory element and an input signal received via an input line, a reference memory cell including a reference memory element, which is disposed along a reference line and which has a resistance value that is a ratio of the first and second resistance values, the reference memory cell generates a reference signal, based on the resistance value of the reference memory element and the input signal, and an output circuit generates an output signal for the output line based on the column signal and the reference signal.
    Type: Application
    Filed: August 8, 2022
    Publication date: September 21, 2023
    Applicants: SAMSUNG ELECTRONICS CO., LTD., Research & Business Foundation SUNGKYUNKWAN UNIVERSITY
    Inventors: Jung Hoon CHUN, Ji Ho SONG, Yoonmyung LEE, Ju A LEE
  • OHPP-FORMULATED NICLOSAMIDE TO TREAT SARS-COV-2, OTHER VIRAL DISEASES, AND CANCERS
    Publication number: 20230293573
    Abstract: The present invention generally relates to a pharmaceutical formulation that substantially increases the bioavailability of niclosamide or a pharmaceutically acceptable salt thereof for a variety of routes of delivery for therapeutic purposes. The newly enhanced formulation also substantially expands the potential therapeutic applications of niclosamide. Pharmaceutical compositions and methods of uses thereof are within the scope of this disclosure.
    Type: Application
    Filed: July 23, 2021
    Publication date: September 21, 2023
    Applicant: Purdue Research Foundation
    Inventors: Yuan Yao, Jingmin Joanne Zhang
  • PYRAZOLYL PYRIMIDINONE COMPOUNDS AND THE USES THEREOF
    Publication number: 20230293523
    Abstract: The present invention relates to a method of treatment for chronic pain, opioid dependence, alcohol use disorder or autism using a class of pyrimidinone compounds, an adenylyl cyclase 1 (AC1) inhibitor. The invention described herein also pertains to pharmaceutical compositions and methods for treating diseases in mammals using those compounds disclosed herein.
    Type: Application
    Filed: May 22, 2023
    Publication date: September 21, 2023
    Applicant: Purdue Research Foundation
    Inventors: Daniel P. Flaherty, Richard M. van Rijn, Val J. Watts, Jason A. Scott
  • BCOR REARRANGEMENTS AND USES THEREOF
    Publication number: 20230295734
    Abstract: Provided herein are methods related to detecting rearrangements in the B-cell lymphoma 6 (BCL6) corepressor (BCOR) or BCL6 corepressor-like protein I (BCORL1) gene, as well as methods of treatment, uses, and kits related thereto. As demonstrated herein, detection of BCOR rearrangements can be used to identify individuals that may benefit from treatment with a targeted therapeutic, such as a CDK inhibitor, an MDM2 inhibitor, a tyrosine kinase inhibitor, a MEK inhibitor, an mTOR inhibitor, or a Hh inhibitor. In some embodiments, the BCOR rearrangement is a fusion gene between BCOR and L3MBTL2, EP300, NUTM2G, MAP7D2, RALGPS1 RGAG1, CREBBP, ING3, NUGGC, or KMT 2D.
    Type: Application
    Filed: March 3, 2021
    Publication date: September 21, 2023
    Applicant: Foundation Medicine, Inc.
    Inventor: Douglas I. LIN
  • APPARATUS FOR CLASSIFYING SOUNDS BASED ON NEURAL CODE IN SPIKING NEURAL NETWORK AND METHOD THEREOF
    Publication number: 20230298573
    Abstract: The present invention relates to an apparatus for classifying sounds based on a neural code in a spiking neural network and a method thereof. A method of classifying sounds based on a neural code in a spiking neural network includes: receiving sounds to be classified and digitally converting the received sounds into sound data; preprocessing the sound data using a multiple neural code-based encoding method including rate code encoding and synchrony code encoding; inputting the preprocessed sound data to a biological spiking neural network to extract features; performing biological spike timing-dependent plasticity (STDP) rule-based learning using the extracted features; and performing classification of the sounds according to neural code propagation characteristics using a test dataset according to a result of the performing of the learning.
    Type: Application
    Filed: April 26, 2023
    Publication date: September 21, 2023
    Applicant: Korea University Research and Business Foundation
    Inventors: Jee hyun KWAG, Ki sung SHIN
  • ENDOLUMINAL PROSTHESIS HAVING MULTIPLE BRANCHES OR FENESTRATIONS AND METHODS OF DEPLOYMENT
    Publication number: 20230293284
    Abstract: A branched and fenestrated prosthesis may include a main tubular graft body including a proximal end opening, a distal end opening, a lumen, and a sidewall. A branch may extend from the sidewall and may include a first end opening, a second end opening, and a lumen. A fenestration may be disposed in the sidewall and positioned distal of the second end opening of the branch. The branched and fenestrated prosthesis may include a plurality of branches and a plurality of fenestrations.
    Type: Application
    Filed: March 17, 2023
    Publication date: September 21, 2023
    Applicants: Cook Medical Technologies LLC, The Cleveland Clinic Foundation
    Inventors: Roy K. Greenberg, Karl J. West, Timothy A. Resch, Blayne A. Roeder
  • MULTISCALE OBJECT DETECTION DEVICE AND METHOD
    Publication number: 20230298309
    Abstract: There is provided a multi-scale object detection device. The device includes an image frame acquisition unit for acquiring a plurality of consecutive image frames, a critical region extractor for extracting at least one second critical region from a current image frame based on at least one first critical region extracted from a previous image frame among the consecutive image frames, a multi-scale object detector whose operation involves a first object detection process for the current image frame and a second object detection process for the at least one second critical region, and an object detection integration unit for integrating the results of the first and second object detection processes.
    Type: Application
    Filed: December 29, 2022
    Publication date: September 21, 2023
    Applicant: University Industry Foundation, Yonsei University
    Inventors: Han Jun KIM, Seon Yeong HEO, Dong Kwan KIM
  • METHOD AND APPARATUS FOR ESTIMATING EXECUTION TIME OF NEURAL NETWORK
    Publication number: 20230297487
    Abstract: A method and apparatus for estimating execution time of a neural network are provided, the method of estimating execution time of a neural network in a multi-core accelerator, the method including generating trace information including operation timing information for each core of the multi-core accelerator, and calculating the execution time of the neural network reflecting communication overhead between cores of the multi-core accelerator and memory access time for each core of the cores, based on the trace information.
    Type: Application
    Filed: August 16, 2022
    Publication date: September 21, 2023
    Applicants: Samsung Electronics Co., Ltd., Industry-Academic Cooperation Foundation, Yonsei University
    Inventors: Myeong Woo KIM, Kunwoo KIM, Changsu KIM, Hanjun KIM
  • INTERMOLECULARLY-FABRICATED COMPOSITION FOR ENCAPSULATING PLANT MATERIALS, AGROCHEMICALS AND PHARMACEUTICALS
    Publication number: 20230295436
    Abstract: This disclosure relates to an intermolecularly-fabricated composition for capturing plant materials, agrochemicals and pharmaceuticals which can simultaneously capture inorganic particulates and organic compounds in which the capture materials have mutual chemical affinity with the composition matrix thereby exhibiting an adhesive property.
    Type: Application
    Filed: March 14, 2023
    Publication date: September 21, 2023
    Applicant: University of Central Florida Research Foundation, Inc.
    Inventors: Jorge Pereira, Giuliana Gan Giannelli, Edwin Davidson, Swadeshmukul Santra, Sebastian Leon
  • DRUG INJECTION ADJUSTING APPARATUS AND METHOD USING REINFORCEMENT LEARNING
    Publication number: 20230293099
    Abstract: A drug injection control device generates a policy model by learning a change in anesthetic state information due to a drug injection rate set so that anesthetic state information of a patient follows target anesthetic state information, generates a prediction model by learning a change in the anesthetic state information according to a change in the drug injection rate, sets the drug injection rate from the anesthetic state information based on the policy model, and predicts expected anesthetic state information from the set drug injection rate and a previously set drug injection rate based on the prediction model.
    Type: Application
    Filed: June 2, 2021
    Publication date: September 21, 2023
    Applicants: Korea University Research and Business Foundation, Seoul National University R&DB Foundation
    Inventors: Joongheon KIM, Myung Jae SHIN, Hyung-Chul LEE
  • METHODS FOR PREVENTING OR TREATING MITOCHONDRIAL PERMEABILITY TRANSITION
    Publication number: 20230293624
    Abstract: The invention provides a method of reducing or preventing mitochondrial permeability transitioning. The method comprises administering an effective amount of an aromatic-cationic peptide having at least one net positive charge; a minimum of four amino acids; a maximum of about twenty amino acids; a relationship between the minimum number of net positive charges (pm) and the total number of amino acid residues (r) wherein 3pm is the largest number that is less than or equal to r+1; and a relationship between the minimum number of aromatic groups (a) and the total number of net positive charges (pt) wherein 2 a is the largest number that is less than or equal to pt+1, except that when a is 1, pt may also be 1.
    Type: Application
    Filed: February 10, 2022
    Publication date: September 21, 2023
    Applicants: Cornell Research Foundation, Inc., Institut De Recherches Cliniques De Montreal
    Inventors: Hazel H. Szeto, Peter W. Schiller, Kesheng Zhao
  • MOLTEN SALT-METAL REACTOR FOR IMPLEMENTING MICRO-REACTOR
    Publication number: 20230298773
    Abstract: The present invention relates to a molten salt-metal reactor for implementing a micro-reactor, and more specifically, to a molten salt-metal reactor including a liquid metal nuclear fuel and a molten salt coolant, wherein the molten salt coolant is disposed in an upper portion of the liquid metal nuclear fuel such that the heat generated from the nuclear fuel is transferred to the molten salt coolant and cooled.
    Type: Application
    Filed: July 13, 2022
    Publication date: September 21, 2023
    Applicants: Korea Advanced Institute of Science and Technology, IUCF-HYU (Industry-University Cooperation Foundation Hanyang University)
    Inventors: Yong Hee KIM, Sung Joong KIM, Won Jun CHOI, Juhyeong LEE, Seongdong JANG, Taesuk OH, Eunhyug LEE
  • PROGRAMMED CELLS FOR TARGETED ARTICULAR CARTILAGE AND BONE REGENERATION
    Publication number: 20230295262
    Abstract: The disclosure describes engineered cells for the treatment of joint and bone disease. The cells are engineered to sense signals only found in diseased compartments and in turn produce therapeutic molecules that are secreted into the local environment.
    Type: Application
    Filed: March 10, 2023
    Publication date: September 21, 2023
    Applicants: Vanderbilt University, University of Tennessee Research Foundation
    Inventors: Jonathan M. Brunger, Karen A. Hasty, Bonnie L. Walton, Craig L. Duvall
  • Systems and methods for processing echocardiogram images
    Patent number: 11763456
    Abstract: The present application includes a method and a software architecture for measuring global longitudinal strain (GLS) and global longitudinal strain rate (GLSr) from 2D echocardiograms. In contrast to conventional GLS computation methods, this approach does not require boundary segmentation and regularization.
    Type: Grant
    Filed: March 11, 2021
    Date of Patent: September 19, 2023
    Assignee: Purdue Research Foundation
    Inventors: Brett Albert Meyers, Pavlos P. Vlachos
  • Method and system for energy aware scheduling for sensors
    Patent number: 11762446
    Abstract: The present invention relates to a method and system energy aware scheduling for sensors (Internet of Things (IoT)). More specifically, the method and system relates to energy scheduling of battery powered sensors or sensors powered using energy harvesters such that accurate and up to date information may be received from said sensors and at the same time minimizing the power utilized by said battery powered or energy harvester powered sensors.
    Type: Grant
    Filed: December 21, 2020
    Date of Patent: September 19, 2023
    Assignee: The Provost, Fellows, Foundation Scholars and the other members of Board, of the College of the Holy and Undivided Trinity of Queen Elizabeth near Dublin
    Inventors: Luiz Da Silva, Jernej Hribar
  • Aluminum alloys with improved intergranular corrosion resistance properties and methods of making and using the same
    Patent number: 11761061
    Abstract: Disclosed herein are embodiments of aluminum-based alloys having improved intergranular corrosion resistance. Methods of making and using the disclosed alloy embodiments also are disclosed herein.
    Type: Grant
    Filed: September 14, 2018
    Date of Patent: September 19, 2023
    Assignees: UT-Battelle, LLC, University of Tennessee Research Foundation, Eck Industries Incorporated, Lawrence Livermore National Security, LLC, Iowa State University Research Foundation, Inc.
    Inventors: Orlando Rios, Hunter B. Henderson, David Weiss, Scott McCall, Eric Thomas Stromme, Zachary Cole Sims, Ryan Ott, Fanqiang Meng, Michael Kesler, Kevin Anderson
  • Quantitative chemical sensors with radio frequency communication
    Patent number: 11761919
    Abstract: A system for low power chemical sensing can include a voltage shift unit which receives a voltage signal from a chemical sensor unit. The voltage signal can be determined by a concentration of an analyte. The voltage shift unit can transform the voltage signal to an input voltage signal, and send the input voltage signal to a plurality of frequency selective surface (FSS) units of an FSS array. The FSS array can communicate a radio frequency (RF) signal in an Institute of Electrical and Electronics Engineers (IEEE) S band with a resonant frequency based on the input voltage to provide the concentration of the analyte.
    Type: Grant
    Filed: July 12, 2019
    Date of Patent: September 19, 2023
    Assignees: University of Utah Research Foundation, The Penn State Research Foundation
    Inventors: Benjamin R. Bunes, Leonard Cardillo, Douglas Later, Ling Zang, Douglas H. Werner, Ronald Jenkins, Micah D. Gregory
  • Method and system of profiling display power
    Patent number: 11763742
    Abstract: A method of determining a model for pixel power consumption for each pixel in a display of a device displaying each color in a color space is disclosed which includes establishing a color space for the display, decomposing the color space into a plurality of subgrids, measuring the pixel power associated with a selected set of colors in each subgrid of the plurality of subgrids, establishing a pixel power model for each subgrid of the plurality of subgrids by applying a function to the power values at the selected set of colors in that subgrid, and deriving a piecewise pixel power model for the entire color space which includes pixel power models for the plurality of subgrids.
    Type: Grant
    Filed: December 12, 2022
    Date of Patent: September 19, 2023
    Assignee: Purdue Research Foundation
    Inventors: Yu Charlie Hu, Pranab Dash