Abstract: Disclosed is a method for the prevention or treatment of vascular leakage-induced diseases and diabetic retinopathy, using C-peptide. Found to prevent extravascular leakage by inhibiting VEGF-induced disassembly of VE-cadherin, C-peptide can be applied to the prevention or treatment of various diabetic complications accompanied by vascular leakage.
Type:
Application
Filed:
August 6, 2013
Publication date:
May 29, 2014
Applicants:
AMOGREENTECH CO., LTD., KANGWON NATIONAL UNIVERSITY UNIVERSITY- INDUSTRY COOPERATION FOUNDATION
Abstract: Provided is a method for managing a group key in a key distribution center. The method includes: receiving a key request from a mobile device; generating a private key for the mobile device using information about a withdrawal time included in the key request; generating a public key and a verification key for the mobile device; and transmitting at least one key including the generated key to the mobile device.
Abstract: Methods for the detection and screening of esophageal adenocarcinoma (EAC) patients and for the monitoring of EAC treatment using a panel or panels of small molecule metabolite biomarkers are disclosed. In other aspects, methods for detection and screening for the progression of high-risk conditions (BE and HGD) to EAC and to monitoring treatment using a panel or panels of small molecule metabolite biomarkers are disclosed. The biomarkers are sensitive and specific for the detection of EAC, and can also be used to classify Barrett's esophagus (BE) and high-grade dysplasia (HGD), which are widely regarded as precursors of EAC.
Type:
Application
Filed:
January 29, 2014
Publication date:
May 29, 2014
Applicant:
Purdue Research Foundation
Inventors:
M. Daniel Raftery, Jian Zhang, Zane Hammoud
Abstract: Disclosed is an apparatus and method for wave power generation of an underwater type, which can be float underwater and can efficiently generate wave power. The apparatus includes a housing formed to have an open bottom end and fixedly connected to the seafloor, a shaft extending from a bottom surface of a top end of the housing, a floater having a top end opened to surround the shaft, positioned at a lower portion of the housing and reciprocating in a perpendicular direction with respect to the housing, and a linear generation unit converting kinetic energy based on the reciprocating motion of the floater into electrical energy.
Type:
Application
Filed:
November 25, 2013
Publication date:
May 29, 2014
Applicant:
Industry-Academic Cooperation Foundation, Yonsei University
Inventors:
Jin Bae Park, Jae Man Kim, Min Kook Song, Seung Kwan Song, Jung Yoon Kim, Jae Seung Kim
Abstract: Disclosed is a power management system that performs power management of a graphic processing unit (GPU). The power management system includes a dynamic voltage and frequency scaling (DVFS) driver configured to include an interface that calls a device driver of the GPU or is called by the device driver, and control an operating voltage and/or an operating frequency of the GPU, and a DVFS governor interface module configured to provide an interface for the DVFS driver to a power management policy module of an operating system (OS). Therefore, in the power management system according to the present invention, a power management policy of the OS based on a change in a workload of the GPU may be applied to the GPU, independently of a hardware configuration of the GPU.
Abstract: The present invention relates to a fusion peptide comprising dhFas-1 domain and MMP substrate and use thereof. More specifically, the present invention relates to a fusion peptide, comprising a) a dhFas-1 domain which is the fourth fas-1 domain of ?ig-h3 lacking H1 and H2 regions; b) a MMP (Matrix metalloproteinase) substrate; and c) a peptide comprising RGD motif and an use thereof for preventing and treating inflammatory disease. The fusion peptide of the present invention inhibits expension of rheumatoid arthritis by adhesion and migration of sinoviocytes and may be used for preventing or treating inflammatory disease by inhibiting infiltration of immune cells.
Type:
Application
Filed:
May 31, 2013
Publication date:
May 29, 2014
Applicant:
Kyungpook National University Industry-Academic Cooperation Foundation
Inventors:
Young Mo Kang, In San Kim, Jin Hee Kang, Keum Hee Sa
Abstract: Highly active and stable platinum-copper (PtCu) electrocatalysts are provided. The PtCu catalysts can be in the form of discrete, spherical PtCu nanoparticles that include a particle interior comprising platinum and copper, and a surface layer comprising platinum surrounding the particle interior. The PtCu nanoparticles can exhibit enhanced oxygen reduction reaction (ORR) activity as compared to other Pt-based catalysts for ORR. The PtCu nanoparticles are also active as electrocatalysts for the oxidation of small molecule organic compounds, including alcohols such as methanol and ethanol.
Abstract: This disclosure examines using lead telluride nanocrystals as well as other materials suitable for thermoelectric conversion, particularly materials with high Figure of Merit values, as coatings on flexible substrates. This disclosure also examines using flexible substrates with lead telluride nanocrystal coatings as sensors.
Abstract: The present invention relates to, inter alia, a method for repressing transcription and/or gene expression from RpoN binding sites (or promoters) or cryptic promoters upstream of RpoN binding sites. The method comprises providing an agent that specifically and selectively binds to RpoN promoter sequences to inhibit or repress the expression of genes downstream of that promoter; and contacting the RpoN promoter with the agent. Agents for repressing transcription and/or gene expression from RpoN promoters are also provided. The agent can be a composition that binds specifically to the ?24, ?12, or ?24/?12 site(s) for RpoN promoter interference. Synthetic peptides, vectors, and host cells are also provided.
Type:
Application
Filed:
May 7, 2012
Publication date:
May 29, 2014
Applicant:
THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK
Inventors:
Christopher T. Nomura, Benjamin R. Lundgren
Abstract: A casting apparatus for a cylinder head and heat treatment method for a cylinder head manufactured by the apparatus is provided. The casting apparatus for a cylinder head is connected with a mold by a pressing unit and a connection pipe and casts a product by pressing and injecting molten metal into the mold. A heat treatment method for the cylinder head manufactured by the apparatus includes: a molten metal supply unit that stores and stabilizes supplied molten metal and a pressing unit that is separately formed from the molten metal supply unit, receives the stabilized molten metal from the molten metal supply unit, and supplies the molten metal to the mold. In addition, a stopper that is soaked in the molten metal in the molten metal supply unit controls the amount of molten metal sent to the pressing unit.
Type:
Application
Filed:
October 24, 2013
Publication date:
May 29, 2014
Applicants:
HYUNDAI MOTOR COMPANY, Kyungpook National University Industry-Academic Cooperation Foundation, KIA MOTORS CORPORATION
Inventors:
Hojae Shin, Byeungkwan Kim, Kyounghee Kim, Byung Joon Ye
Abstract: Provided are compounds for inhibiting Snail-p53 binding and therapeutic agents for cancer including the compounds as an effective component. The Snail-p53 binding inhibitors induce expression of p53 in K-Ras mutant cell lines, thereby enabling effective treatment or prevention of K-Ras mutant cancer, such as, pancreatic cancer, lung cancer, cholangioma, and colon cancer, of which diagnosis or treatment is not easy.
Type:
Application
Filed:
December 31, 2013
Publication date:
May 29, 2014
Applicants:
THE INDUSTRY & ACADEMIC COOPERATION IN CHUNGNAM NATIONAL UNIVERSITY, PUSAN NATIONAL UNIVERSITY INDUSTRY-UNIVERSITY COOPERATION FOUNDATION
Inventors:
Bum Joon PARK, Nam Chul Ha, Sun Hye Lee, Gyu Yong Song, Jee Hyun Lee
Abstract: The present disclosure relates to a light emitting device using a graphene quantum dot, and an organic light emitting device including the same.
Type:
Application
Filed:
November 27, 2013
Publication date:
May 29, 2014
Applicant:
RESEARCH & BUSINESS FOUNDATION SUNGKYUNKWAN UNIVERSITY
Inventors:
Hyoyoung Lee, Jung Hyun Lee, Yong Hun Shin
Abstract: A method of attaching reduced graphene oxide and/or graphene oxide to a polymer layer that includes: forming a polymer layer having a hydrophobic, exterior surface; subjecting the hydrophobic, exterior surface of the polymer layer to ultraviolet/ozone (UV/O3) exposure to change the hydrophobic, exterior surface to a hydrophilic, exterior surface; and applying reduced graphene oxide and/or graphene oxide to the hydrophilic surface of the polymer layer. The UV/O3 exposure reduces the contact angle of droplets on the exterior surface of the polymer layer so that greater amounts of reduced graphene oxide and/or graphene oxide can be applied to the surface.
Type:
Application
Filed:
November 27, 2013
Publication date:
May 29, 2014
Applicant:
The Research Foundation for The State University of New York
Inventors:
Miriam Rafailovich, Rebecca Isseroff, Andrew Chen, Sneha Chittabathini, Alexandra Tse
Abstract: The invention provides novel compositions based on a structure designated as “Honaucin A”, including Honaucin A variants and analogs, and pharmaceutical compositions, liposomes and nanoparticles comprising them, and methods of making and using them. In one embodiment these Honaucin A compounds, and variants and analogs thereof are used to ameliorate (including to treat or prevent) inflammation. In one embodiment, these Honaucin A compounds, and variants and analogs thereof are used to ameliorate (including to treat or prevent) inflammation. In one embodiment, these Honaucin A compounds, and variants and analogs thereof are used as bacterial quorumsensing inhibitors. Accordingly, in alternative embodiments the compositions of the invention are used as anti-bacterial agents.
Type:
Application
Filed:
June 3, 2011
Publication date:
May 29, 2014
Applicants:
UNIVERSITY OF RHODE ISLAND RESEARCH FOUNDATION, THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
Inventors:
William Gerwick, Lena Gerwick, Huykjae Choi, Francisco Villa, Jennifer Smith, David C Rowley
Abstract: The present invention relates to a novel use of a flavone-based compound or a Kaempferia parviflora extract comprising the same. More particularly, the present invention relates to a composition for wrinkle improvement, anti-aging and skin elasticity enhancement or a composition for skin moisturization, which comprises a flavone-based compound or a Kaempferia parviflora extract comprising the same as an active ingredient. The composition of the present invention is very effective in inhibiting the activity of Collagenase-1 (MMP-1) and promoting the synthesis of collagen. Therefore, the composition of the present invention is useful for wrinkle improvement, anti-aging, skin elasticity enhancement, and skin moisturization via the inhibition of moisture loss from the skin.
Type:
Application
Filed:
July 19, 2013
Publication date:
May 29, 2014
Applicant:
Industry-Academic Cooperation Foundation, Yonsei University
Abstract: We present a method for parallel axial imaging, or z-microscopy, utilizing an array of tilted micro mirrors arranged along the axial direction. Image signals emitted from different axial positions can be orthogonally reflected by the corresponding micro mirrors and spatially separated for parallel detection, essentially converting the more challenging axial imaging to a lateral imaging problem. Each micro mirror also provides optical sectioning capability due to its finite dimension.
Abstract: A network broadcast method using a MAC unicast and an MPR node allows a source node to transmit a data packet to at least one MPR node which is located within one-hop distance from the source node and allows the at least one MPR node to transmit the data packet to each next-ranked MPR nodes. At least one normal node, which is not an MPR node while being located within one-hop distance from the source node, receives the data packet of the source node, which is transferred from the source node to an MPR node or transferred between MPR nodes through overhearing. Although the source node and MPR nodes are in a hidden-node relationship, collision is prevented, thereby minimizing data packet loss to improve the transmission reliability, and enabling the data packet of the source node to be reliably broadcasted on a network.
Type:
Application
Filed:
November 1, 2011
Publication date:
May 29, 2014
Applicant:
Research & Business Foundation Sungkyunkwan University
Inventors:
Tae-Jin Lee, Chang-Yeong Oh, Pyeong Soo Mah, Ji Hyoung Ahn, Woo Suk Cha, Jongho Park, Mingyu Lee
Abstract: A scleral lens is provided with a sodium channel blocker or a sodium channel modulator disposed in the pre-corneal tear film between the scleral lens and the cornea. This system can be used to deliver sodium channel blockers or a sodium channel modulators not currently used because of poor bioavailability. Methods of using this sodium channel blocker delivery system or a sodium channel modulator delivery system are also disclosed.
Abstract: A brake drum is provided having an inner drum defining an outboard, radially inwardly extending flange. The flange defines a first plurality of apertures configured to receive fasteners for coupling the inner drum to a wheel. The inner drum further defines a braking surface. The brake drum further includes an outer drum configured to receive the inner drum therein. The outer drum defines an outboard, radially inwardly extending flange defining a second plurality of apertures aligned with the first plurality of apertures and configured to receive the fasteners for coupling the outer drum to the wheel. The inner drum is comprised of a first material such as iron while the outer drum is comprised of a second material such as aluminum.
Abstract: A field effect transistor using a channel layer including a phosphorus-doped graphene and a method of fabricating the same are provided. Further, a phosphorus-doped graphene and a method of producing the same are provided. The field effect transistor includes: a source electrode and a drain electrode formed on a substrate; and a channel layer comprising a phosphorus-doped graphene, the channel layer electrically connected to the source electrode and the drain electrode.
Type:
Application
Filed:
August 7, 2013
Publication date:
May 29, 2014
Applicant:
RESEARCH & BUSINESS FOUNDATION SUNGKYUNKWAN UNIVERSITY